CR9462A - Inhibidores de la dipeptidil peptidasa-iv - Google Patents

Inhibidores de la dipeptidil peptidasa-iv

Info

Publication number
CR9462A
CR9462A CR9462A CR9462A CR9462A CR 9462 A CR9462 A CR 9462A CR 9462 A CR9462 A CR 9462A CR 9462 A CR9462 A CR 9462A CR 9462 A CR9462 A CR 9462A
Authority
CR
Costa Rica
Prior art keywords
inhibitors
dpp
compounds
present
peptidasa
Prior art date
Application number
CR9462A
Other languages
English (en)
Inventor
Kroth Heiko
Feuerstein Tim
Richter Frank
Boer Jurgen
Essers Michael
Nolte Bert
Hochguertel Matthias
Frickel Fritz-Frieder
Taveras Arthur
Steeneck Christoph
Schneider Matthias
Original Assignee
Alantos Pharmaceuticals Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36694223&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CR9462(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Alantos Pharmaceuticals Holdings Inc filed Critical Alantos Pharmaceuticals Holdings Inc
Publication of CR9462A publication Critical patent/CR9462A/es

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    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
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    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Ophthalmology & Optometry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Reproductive Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Psychology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gynecology & Obstetrics (AREA)
  • AIDS & HIV (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

La presente invencion se refiere en general a compuestos inhibidores de la DPP-IV de pirrolidina y tiazolidina. La presente invencion tambien provee metodos de sintesis para la preparacion de tales compuestos, metodos para inhibir la DPP-IV usando tales compuestos y formulaciones farmaceuticas que los contienen para el tratamiento de enfermedades mediadas por DPP-IV, en particular, la diabetes tipo 2.
CR9462A 2005-04-22 2007-10-22 Inhibidores de la dipeptidil peptidasa-iv CR9462A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US67415105P 2005-04-22 2005-04-22

Publications (1)

Publication Number Publication Date
CR9462A true CR9462A (es) 2008-04-16

Family

ID=36694223

Family Applications (1)

Application Number Title Priority Date Filing Date
CR9462A CR9462A (es) 2005-04-22 2007-10-22 Inhibidores de la dipeptidil peptidasa-iv

Country Status (19)

Country Link
US (3) US7553861B2 (es)
EP (1) EP1888562B1 (es)
JP (2) JP4568361B2 (es)
KR (1) KR20080000665A (es)
CN (1) CN101277949A (es)
AP (1) AP2007004234A0 (es)
AU (2) AU2006239929B2 (es)
BR (1) BRPI0608469A2 (es)
CA (1) CA2599419A1 (es)
CR (1) CR9462A (es)
EA (1) EA200702208A1 (es)
ES (1) ES2477868T3 (es)
IL (1) IL186607A0 (es)
MA (1) MA29387B1 (es)
MX (1) MX2007011453A (es)
NO (1) NO20075973L (es)
TN (1) TNSN07244A1 (es)
WO (1) WO2006116157A2 (es)
ZA (1) ZA200708179B (es)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
EP1888562B1 (en) * 2005-04-22 2014-06-18 Alantos Pharmaceuticals Holding, Inc. Dipeptidyl peptidase-iv inhibitors
WO2007050485A2 (en) * 2005-10-25 2007-05-03 Merck & Co., Inc. Combination of a dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension
US8414921B2 (en) * 2005-12-16 2013-04-09 Merck Sharp & Dohme Corp. Pharmaceutical compositions of combinations of dipeptidyl peptidase-4 inhibitors with metformin
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