CU24275B1 - Derivados de cicloalquilo pirrolo [2,3-d] pirimidina-4-il amino útiles como inhibidores de quinasas janus relacionadas y composiciones farmacéuticas que contienen tales compuestos - Google Patents

Derivados de cicloalquilo pirrolo [2,3-d] pirimidina-4-il amino útiles como inhibidores de quinasas janus relacionadas y composiciones farmacéuticas que contienen tales compuestos

Info

Publication number: CU24275B1
Authority: CU; Cuba
Prior art keywords: derivatives; inhibitors; cyclalquylcal; pirimidina; pirrolo
Prior art date: 2013-02-22

Application number

CUP2015000078A

Other languages

English (en)

Spanish (es)

Other versions

CU20150078A7 (es

Inventor

Matthew Frank Brown

Ashley Edward Fenwick

Mark Edward Flanagan

Andrea Gonzales

Timothy Allan Johnson

Neelu Kaila

Mark J Mitton-Fry

Mihir D Parikh

Joseph Walter Strohbach

Ruth E Tenbrink

John David Trzupek

Rayomand Jal Unwalla

Michael L Vazquez

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-02-22

Filing date

2014-02-11

Publication date

2017-10-05

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50151346&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CU24275(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2014-02-11 Application filed by Pfizer filed Critical Pfizer

2016-01-29 Publication of CU20150078A7 publication Critical patent/CU20150078A7/es

2017-10-05 Publication of CU24275B1 publication Critical patent/CU24275B1/xx

Links

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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
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- A61K31/5386—1,4-Oxazines, e.g. morpholine spiro-condensed or forming part of bridged ring systems
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
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- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member

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Organic Chemistry (AREA)
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Animal Behavior & Ethology (AREA)
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Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
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CUP2015000078A 2013-02-22 2014-02-11 Derivados de cicloalquilo pirrolo [2,3-d] pirimidina-4-il amino útiles como inhibidores de quinasas janus relacionadas y composiciones farmacéuticas que contienen tales compuestos CU24275B1 (es)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201361767947P	2013-02-22	2013-02-22
PCT/IB2014/058889 WO2014128591A1 (fr)	2013-02-22	2014-02-11	Dérivés de pyrrolo[2,3-d]pyrimidine en tant qu'inhibiteurs de janus kinases (jak)

Publications (2)

Publication Number	Publication Date
CU20150078A7 CU20150078A7 (es)	2016-01-29
CU24275B1 true CU24275B1 (es)	2017-10-05

Family

ID=50151346

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CUP2015000078A CU24275B1 (es)	2013-02-22	2014-02-11	Derivados de cicloalquilo pirrolo [2,3-d] pirimidina-4-il amino útiles como inhibidores de quinasas janus relacionadas y composiciones farmacéuticas que contienen tales compuestos

Country Status (48)

Country	Link
US (3)	US9035074B2 (fr)
EP (2)	EP2958921B1 (fr)
JP (2)	JP6145179B2 (fr)
KR (1)	KR101787858B1 (fr)
CN (2)	CN105008362B (fr)
AP (1)	AP2015008664A0 (fr)
AR (1)	AR094857A1 (fr)
AU (1)	AU2014220357B2 (fr)
BR (1)	BR112015019634B1 (fr)
CA (1)	CA2900703C (fr)
CL (1)	CL2015002303A1 (fr)
CR (1)	CR20150395A (fr)
CU (1)	CU24275B1 (fr)
CY (3)	CY1119502T1 (fr)
DK (2)	DK3290421T3 (fr)
DO (1)	DOP2015000206A (fr)
EA (1)	EA027879B1 (fr)
ES (2)	ES2647525T3 (fr)
FR (1)	FR22C1006I2 (fr)
GE (1)	GEP201606600B (fr)
HR (2)	HRP20171599T2 (fr)
HU (3)	HUE041778T2 (fr)
IL (1)	IL240132B (fr)
LT (3)	LT3290421T (fr)
LU (1)	LUC00261I2 (fr)
MA (1)	MA38347A1 (fr)
MD (1)	MD4735C1 (fr)
ME (2)	ME03301B (fr)
MX (1)	MX374338B (fr)
MY (1)	MY177476A (fr)
NL (1)	NL301155I2 (fr)
NO (2)	NO3052752T3 (fr)
NZ (1)	NZ710411A (fr)
PE (1)	PE20151764A1 (fr)
PH (1)	PH12015501779B1 (fr)
PL (2)	PL2958921T3 (fr)
PT (2)	PT2958921T (fr)
PY (1)	PY1407086A (fr)
RS (2)	RS58245B1 (fr)
SG (1)	SG11201505816UA (fr)
SI (2)	SI2958921T1 (fr)
TN (1)	TN2015000355A1 (fr)
TR (1)	TR201902525T4 (fr)
TW (1)	TWI507408B (fr)
UA (1)	UA111804C2 (fr)
UY (1)	UY35337A (fr)
WO (1)	WO2014128591A1 (fr)
ZA (1)	ZA201505454B (fr)

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CN108794480A (zh) *	2017-04-28	2018-11-13	天津药物研究院有限公司	吡咯并嘧啶类化合物、其制备方法和用途
BR112020018094A2 (pt)	2018-03-08	2020-12-22	Incyte Corporation	Compostos de aminopirazina diol como inibidores de pi3k-¿
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Publication number	Publication date
LT2958921T (lt)	2017-11-27
WO2014128591A1 (fr)	2014-08-28
CA2900703C (fr)	2017-11-28
UA111804C2 (uk)	2016-06-10
BR112015019634B1 (pt)	2022-09-20
FR22C1006I1 (fr)	2022-03-25
JP6145179B2 (ja)	2017-06-07
SI3290421T1 (sl)	2019-03-29
EP2958921B1 (fr)	2017-09-20
IL240132A0 (en)	2015-09-24
SI2958921T1 (sl)	2017-12-29
HRP20171599T2 (hr)	2018-11-16
ME03301B (fr)	2019-07-20
CA2900703A1 (fr)	2014-08-28
UY35337A (es)	2014-09-30
CR20150395A (es)	2015-09-23
AR094857A1 (es)	2015-09-02
EP3290421A1 (fr)	2018-03-07
CU20150078A7 (es)	2016-01-29
US9545405B2 (en)	2017-01-17
LUC00261I2 (fr)	2025-04-25
DK3290421T3 (en)	2019-03-18
DOP2015000206A (es)	2016-02-15
AU2014220357A1 (en)	2015-08-06
KR101787858B1 (ko)	2017-10-18
GEP201606600B (en)	2017-01-10
HRP20190152T1 (hr)	2019-03-22
IL240132B (en)	2020-09-30
JP2017165762A (ja)	2017-09-21
EP3290421B1 (fr)	2019-01-02
EP2958921A1 (fr)	2015-12-30
PY1407086A (es)	2017-10-02
PH12015501779A1 (en)	2015-12-02
HK1213881A1 (zh)	2016-07-15
US9035074B2 (en)	2015-05-19
MD4735C1 (ro)	2021-07-31
TWI507408B (zh)	2015-11-11
NO3052752T3 (fr)	2018-06-16
US20150225408A1 (en)	2015-08-13
TR201902525T4 (tr)	2019-03-21
RS56503B1 (sr)	2018-02-28
MX374338B (es)	2025-03-06
CY1119502T1 (el)	2018-03-07
HUE041778T2 (hu)	2019-05-28
HUS2200003I1 (hu)	2022-02-28
MX2015010928A (es)	2015-10-29
EA027879B1 (ru)	2017-09-29
PE20151764A1 (es)	2015-12-03
US9549929B2 (en)	2017-01-24
PL3290421T3 (pl)	2019-05-31
ZA201505454B (en)	2016-07-27
NO2022004I1 (no)	2022-02-01
JP2016509049A (ja)	2016-03-24
PT3290421T (pt)	2019-03-01
CL2015002303A1 (es)	2015-12-18
BR112015019634A2 (pt)	2019-12-17
PH12015501779B1 (en)	2015-12-02
DK2958921T3 (da)	2017-11-06
US20150246048A1 (en)	2015-09-03
HUE037192T2 (hu)	2018-08-28
CN105008362A (zh)	2015-10-28
CY1121468T1 (el)	2020-05-29
AP2015008664A0 (en)	2015-08-31
LT3290421T (lt)	2019-02-25
SG11201505816UA (en)	2015-09-29
FR22C1006I2 (fr)	2023-01-27
CN105008362B (zh)	2017-06-06
US20140243312A1 (en)	2014-08-28
CN107089985B (zh)	2019-06-07
MY177476A (en)	2020-09-16
CN107089985A (zh)	2017-08-25
PL2958921T3 (pl)	2018-01-31
AU2014220357B2 (en)	2017-04-27
ES2647525T3 (es)	2017-12-22
NL301155I2 (nl)	2022-02-23
PT2958921T (pt)	2017-11-20
MD4735B1 (ro)	2020-12-31
LTC2958921I2 (fr)	2024-03-25
RS58245B1 (sr)	2019-03-29
NL301155I1 (fr)	2021-12-22
HRP20171599T1 (hr)	2017-12-01
TN2015000355A1 (fr)	2017-01-03
KR20150109434A (ko)	2015-10-01
MD20150073A2 (ro)	2016-01-31
NZ710411A (en)	2017-11-24
CY2022003I1 (el)	2022-03-24
CY2022003I2 (el)	2022-03-24
ES2713052T3 (es)	2019-05-17
MA38347A1 (fr)	2017-10-31
LTPA2022502I1 (fr)	2022-03-10
TW201443055A (zh)	2014-11-16
ME02904B (fr)	2018-04-20
EA201591255A1 (ru)	2016-03-31

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