DD261154A5 - Verfahren zur herstellung einer hypoglykaemisch wirksamen thiozolidindion-verbindung - Google Patents

Verfahren zur herstellung einer hypoglykaemisch wirksamen thiozolidindion-verbindung Download PDF

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Publication number
DD261154A5
DD261154A5 DD86290390A DD29039086A DD261154A5 DD 261154 A5 DD261154 A5 DD 261154A5 DD 86290390 A DD86290390 A DD 86290390A DD 29039086 A DD29039086 A DD 29039086A DD 261154 A5 DD261154 A5 DD 261154A5
Authority
DD
German Democratic Republic
Prior art keywords
mixture
compound
mmol
benzyl
oil
Prior art date
Application number
DD86290390A
Other languages
German (de)
English (en)
Inventor
James F Eggler
Gerald F Holland
Michael R Johnson
Robert A Volkmann
Original Assignee
������@���Kk��
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ������@���Kk�� filed Critical ������@���Kk��
Publication of DD261154A5 publication Critical patent/DD261154A5/de

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Emergency Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Pyrane Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Soil Working Implements (AREA)
  • Saccharide Compounds (AREA)
  • Detergent Compositions (AREA)
DD86290390A 1985-05-21 1986-05-20 Verfahren zur herstellung einer hypoglykaemisch wirksamen thiozolidindion-verbindung DD261154A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1985/000962 WO1986007056A1 (fr) 1985-05-21 1985-05-21 Diones de thiazolidine hypoglycemique

Publications (1)

Publication Number Publication Date
DD261154A5 true DD261154A5 (de) 1988-10-19

Family

ID=22188690

Family Applications (1)

Application Number Title Priority Date Filing Date
DD86290390A DD261154A5 (de) 1985-05-21 1986-05-20 Verfahren zur herstellung einer hypoglykaemisch wirksamen thiozolidindion-verbindung

Country Status (26)

Country Link
US (1) US4703052A (fr)
EP (1) EP0207605B1 (fr)
JP (1) JPS61271287A (fr)
KR (1) KR870000903B1 (fr)
CN (1) CN1007248B (fr)
AT (1) ATE50256T1 (fr)
AU (2) AU560179B2 (fr)
CA (1) CA1279320C (fr)
DD (1) DD261154A5 (fr)
DE (1) DE3668892D1 (fr)
DK (1) DK233586A (fr)
EG (1) EG18043A (fr)
ES (1) ES8707210A1 (fr)
FI (1) FI89268C (fr)
GR (1) GR861297B (fr)
HU (1) HU210339B (fr)
IE (1) IE58674B1 (fr)
IL (1) IL78831A (fr)
MY (1) MY108496A (fr)
NO (1) NO166448C (fr)
PH (2) PH22313A (fr)
PL (1) PL147479B1 (fr)
PT (1) PT82610B (fr)
WO (1) WO1986007056A1 (fr)
YU (1) YU44573B (fr)
ZA (1) ZA863762B (fr)

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WO1989008650A1 (fr) * 1988-03-08 1989-09-21 Pfizer Inc. Agents hypoglycemiques de thiazolidinedione
WO1989008652A1 (fr) * 1988-03-08 1989-09-21 Pfizer Inc. Derives de thiazolidinedione comme agents hypoglycemiques
US5120754A (en) * 1988-03-08 1992-06-09 Pfizer Inc. Thiazolidinedione hypoglycemic agents
US5330998A (en) * 1988-03-08 1994-07-19 Pfizer Inc. Thiazolidinedione derivatives as hypoglycemic agents
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WO1991007107A1 (fr) * 1989-11-13 1991-05-30 Pfizer Inc. Agents d'oxazolidinedione hypoglycemiques
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ATE205206T1 (de) * 1990-04-27 2001-09-15 Sankyo Co Benzylidenthiazolidinderivate, ihre herstellung und ihre anwendung als lipidperoxid-inhibitoren
US5037842A (en) * 1990-06-05 1991-08-06 Pfizer Inc. Oxa- and thiazolidinedione hypoglycemic and hypocholesterolemic agents
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WO1992003425A1 (fr) * 1990-08-23 1992-03-05 Pfizer Inc. Derives d'hydroxy-uree hypoglycemique
US5158966A (en) * 1991-02-22 1992-10-27 The University Of Colorado Foundation, Inc. Method of treating type i diabetes
TW222626B (fr) 1991-07-22 1994-04-21 Pfizer
FR2680512B1 (fr) * 1991-08-20 1995-01-20 Adir Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
DE4142190A1 (de) * 1991-12-20 1993-06-24 Bayer Ag Verfahren zur herstellung von optisch aktiven (alpha)-hydroxycarbonsaeuren
FR2688220A1 (fr) * 1992-03-06 1993-09-10 Adir Nouveaux derives de thiazolidine-2,4-dione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
US5498621A (en) * 1992-05-01 1996-03-12 Pfizer Inc. Oxazolidinedione hypoglycemic agents
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US5594016A (en) * 1992-12-28 1997-01-14 Mitsubishi Chemical Corporation Naphthalene derivatives
JP2845743B2 (ja) * 1992-12-28 1999-01-13 三菱化学株式会社 新規なナフタレン誘導体
JP3195455B2 (ja) * 1993-01-06 2001-08-06 ウェルファイド株式会社 キノリン−３−酢酸誘導体、その製造法と用途
DE4317320A1 (de) * 1993-05-25 1994-12-01 Boehringer Mannheim Gmbh Neue Thiazolidindione und diese enthaltende Arzneimittel
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US5478852C1 (en) * 1993-09-15 2001-03-13 Sankyo Co Use of thiazolidinedione derivatives and related antihyperglycemic agents in the treatment of impaired glucose tolerance in order to prevent or delay the onset of noninsulin-dependent diabetes mellitus
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US5594015A (en) * 1994-06-22 1997-01-14 Regents Of The University Of California Thiazolidine derivatives for the treatment of psoriasis
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WO1999018066A1 (fr) 1997-10-02 1999-04-15 Sankyo Company, Limited Derives d'acide amidocarboxylique
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Also Published As

Publication number Publication date
NO166448C (no) 1991-07-24
KR860009010A (ko) 1986-12-19
ZA863762B (en) 1988-05-25
HU210339B (en) 1995-03-28
JPH0586953B2 (fr) 1993-12-14
EP0207605A1 (fr) 1987-01-07
JPS61271287A (ja) 1986-12-01
NO870241D0 (no) 1987-01-20
NO166448B (no) 1991-04-15
DK233586D0 (da) 1986-05-20
CN86104075A (zh) 1987-03-11
FI870219L (fi) 1987-01-20
MY108496A (en) 1996-10-31
IE58674B1 (en) 1993-11-03
NO870241L (no) 1987-03-20
KR870000903B1 (ko) 1987-05-04
ATE50256T1 (de) 1990-02-15
WO1986007056A1 (fr) 1986-12-04
PH25226A (en) 1991-03-27
PT82610B (pt) 1988-11-30
EP0207605B1 (fr) 1990-02-07
GR861297B (en) 1986-09-16
CA1279320C (fr) 1991-01-22
EG18043A (en) 1992-11-30
FI89268C (fi) 1993-09-10
IL78831A (en) 1990-11-29
IL78831A0 (en) 1986-09-30
AU5758086A (en) 1987-01-08
DE3668892D1 (en) 1990-03-15
YU83786A (en) 1987-12-31
AU7507487A (en) 1987-10-15
ES555147A0 (es) 1987-07-16
HUT45247A (en) 1988-06-28
IE861336L (en) 1986-11-21
US4703052A (en) 1987-10-27
FI89268B (fi) 1993-05-31
PT82610A (en) 1986-06-01
PL147479B1 (en) 1989-06-30
AU560179B2 (en) 1987-04-02
DK233586A (da) 1986-11-22
CN1007248B (zh) 1990-03-21
PH22313A (en) 1988-07-29
AU583991B2 (en) 1989-05-11
ES8707210A1 (es) 1987-07-16
FI870219A0 (fi) 1987-01-20
YU44573B (en) 1990-10-31

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ENJ Ceased due to non-payment of renewal fee