DK0468257T3 - Multimer form af human rhinovirusreceptorprotein - Google Patents

Multimer form af human rhinovirusreceptorprotein

Info

Publication number
DK0468257T3
DK0468257T3 DK91111272T DK91111272T DK0468257T3 DK 0468257 T3 DK0468257 T3 DK 0468257T3 DK 91111272 T DK91111272 T DK 91111272T DK 91111272 T DK91111272 T DK 91111272T DK 0468257 T3 DK0468257 T3 DK 0468257T3
Authority
DK
Denmark
Prior art keywords
human rhinovirus
infectivity
hrv
receptor protein
rhinovirus receptor
Prior art date
Application number
DK91111272T
Other languages
Danish (da)
English (en)
Inventor
Jeffrey M Greve
Alan Mcclelland
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0468257T3 publication Critical patent/DK0468257T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70525ICAM molecules, e.g. CD50, CD54, CD102
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DK91111272T 1990-07-20 1991-07-06 Multimer form af human rhinovirusreceptorprotein DK0468257T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US55623890A 1990-07-20 1990-07-20

Publications (1)

Publication Number Publication Date
DK0468257T3 true DK0468257T3 (da) 2000-03-27

Family

ID=24220489

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91111272T DK0468257T3 (da) 1990-07-20 1991-07-06 Multimer form af human rhinovirusreceptorprotein

Country Status (14)

Country Link
US (1) US6096862A (fr)
EP (2) EP0987329A3 (fr)
JP (1) JP3091527B2 (fr)
KR (1) KR100208847B1 (fr)
AT (1) ATE184049T1 (fr)
DE (1) DE69131564T2 (fr)
DK (1) DK0468257T3 (fr)
ES (1) ES2134762T3 (fr)
FI (1) FI105687B (fr)
GR (1) GR3031768T3 (fr)
IE (1) IE912552A1 (fr)
IL (1) IL98866A0 (fr)
PT (1) PT98394B (fr)
ZA (1) ZA915678B (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143298A (en) * 1988-09-01 2000-11-07 Bayer Corporation Soluble truncated forms of ICAM-1
US6514936B1 (en) 1988-09-01 2003-02-04 Bayer Corporation Antiviral methods using human rhinovirus receptor (ICAM-1)
US6051231A (en) * 1988-09-01 2000-04-18 Bayer Corporation Antiviral methods and prepations
ES2141076T3 (es) 1988-09-01 2000-03-16 Bayer Ag Proteina del receptor de rinovirus humano que inhibe la infectividad del virus.
ES2134762T3 (es) * 1990-07-20 1999-10-16 Bayer Ag Formas multimericas de proteinas receptoras de rinovirus humanos.
US6107461A (en) * 1990-07-20 2000-08-22 Bayer Corporation Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
US6130202A (en) * 1990-07-20 2000-10-10 Bayer Corporation Antiviral methods
US5629162A (en) * 1991-06-11 1997-05-13 The Center For Blood Research Method of identifying agents which modulate ICAM-3 binding to LFA-1
US5852170A (en) * 1992-01-27 1998-12-22 Icos Corporation ICAM-4 materials and methods
US5837822A (en) * 1992-01-27 1998-11-17 Icos Corporation Humanized antibodies specific for ICAM related protein
US6818743B1 (en) 1992-01-27 2004-11-16 Icos Corporation I-CAM related protein
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US5989843A (en) * 1992-01-27 1999-11-23 Icos Corporation Methods for identifying modulators of protein kinase C phosphorylation of ICAM-related protein
US5702917A (en) * 1992-01-27 1997-12-30 Icos Corporation Polynucleotides encoding human ICAM-4
US5700658A (en) * 1992-01-27 1997-12-23 Icos Corporation ICAM-4 materials and methods
US5773293A (en) * 1992-01-27 1998-06-30 Icos Corporation Anti-ICAM-4 antibodies and hybridomas
US5753502A (en) * 1993-08-05 1998-05-19 Icos Corporation Neuron-specific ICAM-4 promoter
WO1993014776A1 (fr) * 1992-01-27 1993-08-05 Icos Corporation Proteine apparentee a icam
US6100383A (en) * 1992-01-27 2000-08-08 Icos Corporation Fusion proteins comprising ICAM-R polypeptides and immunoglobulin constant regions
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
US6153395A (en) * 1992-01-27 2000-11-28 Icos Corporation ICAM-related protein
US5811517A (en) * 1992-01-27 1998-09-22 Icos Corporation ICAM-related protein variants
JPH06510208A (ja) * 1992-06-22 1994-11-17 マイルス・インコーポレーテツド 多量体形態のヒトライノウイルスレセプタ蛋白質
US5879712A (en) 1995-06-07 1999-03-09 Sri International Method for producing drug-loaded microparticles and an ICAM-1 dosage form so produced
US6867203B2 (en) 1998-12-29 2005-03-15 Abbott Laboratories Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds
CA2407426A1 (fr) * 2000-04-28 2001-11-08 Planet Biotechnology, Inc. Nouvelle immunoadhesine destinee a la prevention d'infections a rhinovirus
US20020168367A1 (en) 2000-04-28 2002-11-14 Planet Biotechnology Incorporated Novel immunoadhesins for treating and preventing viral and bacterial diseases
EP2007401A2 (fr) * 2006-04-04 2008-12-31 Marinomed Biotechnologie GmbH Polymère anti-inflammatoire
US20080131454A1 (en) * 2006-12-05 2008-06-05 Marinomed Biotechnologie Gmbh Methods and Compositions for the Treatment of Rhinovirus Infections with Carrageenan

Family Cites Families (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171365A (en) * 1977-08-05 1979-10-16 Sterling Drug Inc. Antiviral aryloxyalkylpyrazoles
US4261928A (en) * 1977-08-05 1981-04-14 Sterling Drug Inc. 2-Benzoyl-8-(2-chloro-4-methoxyphenoxy)-1-phenyl-1-octanone
US4209526A (en) * 1977-08-05 1980-06-24 Sterling Drug Inc. Antiviral arylenedioxyalkyl substituted pyrazoles
FR2432170A1 (fr) * 1978-06-12 1980-02-22 Corning Glass Works Procede de mesure de recepteurs d'antigene sur des membranes de cellules
US4234725A (en) * 1979-10-24 1980-11-18 Sterling Drug Inc. 4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-[4-(4-morpholinyl)-1-oxobutyl]-1H-pyrazole
US4232161A (en) * 1979-10-24 1980-11-04 Sterling Drug Inc. 4-[6-(2-Chloro-4-methoxyphenoxy)hexyl]-3,5-diethyl-1-(2-pyridinyl)-1H-pyrazole
US5179017A (en) * 1980-02-25 1993-01-12 The Trustees Of Columbia University In The City Of New York Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials
US4427653A (en) * 1981-01-26 1984-01-24 President And Fellows Of Harvard College Method of making monoclonal antibodies
US4372976A (en) * 1981-08-07 1983-02-08 Sterling Drug Inc. Novel aryl-aliphatic ketone and its use as an antiviral agent
US4451476A (en) * 1982-12-13 1984-05-29 Sterling Drug Inc. Isoxazoles as antiviral agents
US4843087A (en) * 1983-08-29 1989-06-27 Sterling Drug Inc. Di-heterocyclic compounds and their use as antiviral agents
EP0169146A3 (fr) * 1984-07-20 1988-07-20 Merck & Co. Inc. Anticoprs monoclonaux dirigés contre le récepteur cellulaire du rhinovirus humain
JPS6181798A (ja) * 1984-07-23 1986-04-25 ベクトン・デイツキンソン・アンド・カンパニ− 細胞リセプタ−の回収
DE3505148A1 (de) * 1985-02-15 1986-10-30 Boehringer Ingelheim International GmbH, 6507 Ingelheim Polypeptide des rhinovirusstammes hrv2 sowie die hierfuer codierenden dna-molekuele
CA1280753C (fr) * 1985-07-02 1991-02-26 Philip Michael Carabateas Methode de preparation de derives de substitution heterocycliques de phenoxyalkylisoxasoles et de phenoxyalkylfuranes
EP0227604A3 (fr) * 1985-12-23 1989-01-18 Sandoz Ag Emploi d'oligopeptides dans le traitement d'infections virales
EP0261403A3 (fr) * 1986-08-23 1988-04-13 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Polypeptide de rhinovirus souche HRV89, et molécule d'ADN qui l'encode
EP0303692A4 (en) * 1987-02-26 1990-12-05 Dana Farber Cancer Institute Cloning of lfa-1
DE3886237T2 (de) * 1987-02-26 1994-05-05 Dana Farber Cancer Inst Inc Reinigung von LFA-3.
DE3712678A1 (de) * 1987-04-14 1988-10-27 Boehringer Ingelheim Int Rezeptor der kleinen rhinovirus rezeptor gruppe
US5304636A (en) * 1987-04-14 1994-04-19 Boehringer Ingelheim International Gmbh Receptor for the human rhinovirus minor group
US5603932A (en) * 1987-04-14 1997-02-18 Boehringer Ingelheim International Gmbh Receptor of the minor human rhinovirus receptor group
US5831036A (en) * 1987-05-04 1998-11-03 Dana Farber Cancer Institute Soluble fragments of human intercellular adhesion molecule-1
US5284931A (en) * 1987-05-04 1994-02-08 Dana Farber Cancer Institute Intercellular adhesion molecules, and their binding ligands
ES2080044T3 (es) * 1987-05-04 1996-02-01 Dana Farber Cancer Inst Inc Moleculas de adhesion intercelular y sus ligandos de fijacion.
AU629189B2 (en) * 1987-05-04 1992-10-01 Dana-Farber Cancer Institute Intercellular adhesion molecules and their binding ligands
US4956281A (en) * 1987-06-03 1990-09-11 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing lymphocyte function associated antigen-3
US5109123A (en) * 1988-06-14 1992-04-28 Dana Farber Cancer Institute Alteration of ability of soluble CD4 fragments to bind HIV
DE3852374T2 (de) * 1987-11-02 1995-05-04 Baylor College Medicine Verwendung von ICAM-1 oder ihre funktionelle Derivate zur Behandlung unspezifischer Entzündungen.
US5081228A (en) * 1988-02-25 1992-01-14 Immunex Corporation Interleukin-1 receptors
CA1341055C (fr) * 1987-12-08 2000-07-18 Alan Mcclelland Lignees cellulaires transfectantes exprimant le recepteur majeur du rhinovirus chez l'homme
US5395929A (en) * 1987-12-15 1995-03-07 Dana Farber Cancer Institute Isolated nucleic acid encoding the alpha subunit of the human leukocyte adhesion receptor
EP0372056A4 (en) * 1988-05-04 1991-05-15 Dana Farber Cancer Institute Protein micelles
EP0364690A3 (fr) * 1988-08-23 1990-07-18 Dana Farber Cancer Institute Sous-unité du récepteur d'adhésion de leukocyte Mac-1
DE68923048T2 (de) * 1988-08-23 1995-11-16 Dana Farber Cancer Inst Inc Alpha-Subeinheit des LFA-1-Leukocyt-Adhäsions-Rezeptors.
ZA896668B (en) * 1988-09-01 1990-06-27 Molecular Therapeutics Inc A human rhinovirus receptor protein that inhibits virus infectivity
ES2141076T3 (es) * 1988-09-01 2000-03-16 Bayer Ag Proteina del receptor de rinovirus humano que inhibe la infectividad del virus.
ES2201052T3 (es) * 1988-09-28 2004-03-16 Dana Farber Cancer Institute Moleculas de adhesion intercelular y sus ligandos de union.
US5372933A (en) * 1988-10-03 1994-12-13 The Scripps Research Institute Polypeptides that mimic receptor-induced binding sites, and methods of using same
NO900155L (no) * 1989-01-24 1990-07-25 Molecular Therapeutics Inc Et opploeselig molekyl som er relatert til, men forskjellig fra icam-1.
US5235049A (en) * 1989-01-24 1993-08-10 Molecular Therapeutics, Inc. Nucleic acid sequences encoding a soluble molecule (SICAM-1) related to but distinct from ICAM-1
PT92900A (pt) * 1989-01-24 1990-07-31 Sistema de vectores de expressao para a producao de anticorpos monoclonais quimericos
CA2008368C (fr) * 1989-01-24 2003-04-08 Jeffrey Greve Molecule soluble apparentee a l'icam-i mais distincte
ES2035668T3 (es) * 1989-03-09 1993-04-16 Boehringer Ingelheim Pharmaceuticals Inc. Uso de moleculas de adherencia intercelular y sus ligandos de union en el tratamiento del asma.
ATE146222T1 (de) * 1989-03-09 1996-12-15 Blood Res Center Interzellulares adhäsions-molekül-2 und seine bindungsliganden
ATE219838T1 (de) * 1989-03-16 2002-07-15 Blood Res Center Verwendung von funktionellen derivaten des interzellulär-adhäsions-moleküls icam-1 in einer antivirus-therapie
HU217792B (hu) * 1989-03-16 2000-04-28 Dana Farber Cancer Institute Eljárás intercelluláris adhéziós molekula (ICAM-1) oldható származékai és ezeket tartalmazó gyógyszerkészítmények előállítására
US5324510A (en) * 1989-09-01 1994-06-28 Boehringer Ingelheim Pharmaceuticals, Inc. Use of antibodies to intercellular adhesion molecule-1 (ICAM-1) in the treatment of asthma
EP0459577A3 (en) * 1990-06-01 1992-08-05 Merck & Co. Inc. Microbially expressed portions of a monoclonal antibody block rhinovirus attachment to cell receptors
US5349053A (en) * 1990-06-01 1994-09-20 Protein Design Labs, Inc. Chimeric ligand/immunoglobulin molecules and their uses
US5686581A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric form of human rhinovirus receptor protein
US5686582A (en) * 1990-07-20 1997-11-11 Bayer Corporation Multimeric forms of human rhinovirus receptor protein
ES2134762T3 (es) * 1990-07-20 1999-10-16 Bayer Ag Formas multimericas de proteinas receptoras de rinovirus humanos.
WO1992003473A1 (fr) * 1990-08-27 1992-03-05 Cetus Corporation Medicaments peptidiques a base de cd18 utilises dans le traitement d'affections
US5288854A (en) * 1990-11-28 1994-02-22 Center For Blood Research, Inc. Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1
WO1992010591A1 (fr) * 1990-12-14 1992-06-25 Cell Genesys, Inc. Chaines chimeriques utilisees comme voies de transduction de signal associe a un recepteur
EP0510483A1 (fr) * 1991-04-22 1992-10-28 Boehringer Ingelheim Pharmaceuticals Inc. Procédé pour la détection des virus
US5223396A (en) * 1991-05-03 1993-06-29 Boehringer Ingelheim Pharmaceuticals, Inc. Method for detecting organ transplant rejection
US5240694A (en) * 1991-09-23 1993-08-31 University Of Virginia Combined antiviral and antimediator treatment of common colds
DE69229275T2 (de) * 1991-10-04 1999-12-30 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Rockville Herstellung eines arzneimittels zur behandlung von augenentzündung durch blockierung von zelladhäsionsmolekulen
US5525487A (en) * 1992-01-27 1996-06-11 Icos Corporation DNA encoding I-CAM related protein
US5532127A (en) * 1992-01-27 1996-07-02 Icos Corporation Assay for 1-CAM related protein expression
WO1993014776A1 (fr) * 1992-01-27 1993-08-05 Icos Corporation Proteine apparentee a icam
DK0566554T3 (da) * 1992-03-13 2000-08-07 Monsanto Co Fremstilling af rekombinante proteiner ved anvendelse af herpesviruspromotorer og VP16-transaktivatorer
US5580969A (en) * 1992-07-24 1996-12-03 The United States Of America As Represented By The Secretary Of The Navy Antisense oligonucleotides directed against human ICAM-I RNA

Also Published As

Publication number Publication date
ZA915678B (en) 1992-05-27
IE912552A1 (en) 1992-01-29
ES2134762T3 (es) 1999-10-16
AU652567B2 (en) 1994-09-01
KR930002511A (ko) 1993-02-23
FI105687B (fi) 2000-09-29
EP0468257A1 (fr) 1992-01-29
EP0468257B1 (fr) 1999-09-01
JP3091527B2 (ja) 2000-09-25
DE69131564T2 (de) 2000-01-13
EP0987329A3 (fr) 2004-03-03
IL98866A0 (en) 1992-07-15
PT98394A (pt) 1992-06-30
AU8117691A (en) 1992-01-23
FI913470A0 (fi) 1991-07-18
DE69131564D1 (de) 1999-10-07
PT98394B (pt) 1999-01-29
GR3031768T3 (en) 2000-02-29
FI913470L (fi) 1992-01-21
ATE184049T1 (de) 1999-09-15
US6096862A (en) 2000-08-01
JPH04297499A (ja) 1992-10-21
EP0987329A2 (fr) 2000-03-22
KR100208847B1 (ko) 1999-07-15

Similar Documents

Publication Publication Date Title
DK0468257T3 (da) Multimer form af human rhinovirusreceptorprotein
NZ230474A (en) Detergent-complexed human rhinovirus receptor: (intercellular adhesion molecule-1 (icam-1) fragments)
AR059902A2 (es) Complejo de factor viii/vwf o factor viii:c
EA199700359A1 (ru) Пептиды и соединения, связывающиеся с тромбопоэтиновым рецептором
DK0488061T3 (da) MAC-1-bindingsposition for ICAM-1
DE69231135D1 (de) CD2 bindender Bereich für das Lymphocyten-Funktion assoziierte Antigen-3
DE69535575D1 (de) Verknüpfte peptid-nukleinsäuren
DK0705846T4 (da) Höjmolekylære og lavmolekylære fraktioner af von Wille-brand-faktor
EP0528931A4 (en) Humanized chimeric anti-icam-1 antibodies, methods of preparation and use
ES2087091T3 (es) Una molecula soluble relacionada pero distinta de la icam-1.
DK0387701T3 (da) Anvendelse af intercellulære adhæsionsmolekyler samt deres bindende ligander ved behandling af astma
DK258789A (da) Peptider, der blokerer bindingen af hiv-1 til cd4 receptorproteinet
RU94046450A (ru) Мультимерная icam-i, способ усиления связывания icam-i с лигандом, фармацевтическая композиция, способ индукции декансидации, способ необратимого ингибирования заражения клеток
MX9206960A (es) Alboagreginas:agonistas de las plaquetas que se ligan a la glicoproteina ib de la membrana de las plaquetas
ATE304054T1 (de) Rekombinante hetero-multimerische proteine von dem alpha-beta c4 bp typ
Natta Failure of the α-thalassemia gene to decrease the severity of sickle cell anemia
KR890002388A (ko) 트롬빈 결합물질 및 그의 제조방법
Tegos et al. Glycosylated hemoglobin A2 components
Petersen et al. Functional properties of the two major hemoglobin components from Leporinus friderici (Pisces)
ES1011118U (es) Senalizador, marcador y separador multiple.
RU92016375A (ru) Днк, содержащая iсам-1, и производные усам-1
ES1003427U (es) Broche para pendientes y similares perfeccionado.
ATE105148T1 (de) Verwendung von naehroelen um nahrungsmittel zu wuerzen.
ES1010310U (es) Mesa para informatica.