FI105687B - Menetelmä terapeuttisesti käyttökelpoisen rhinoviruksen reseptoriproteiinin multimeerin valmistamiseksi - Google Patents

Menetelmä terapeuttisesti käyttökelpoisen rhinoviruksen reseptoriproteiinin multimeerin valmistamiseksi Download PDF

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Publication number: FI105687B
Authority: FI; Finland
Prior art keywords: icam; ticam; binding; multimeric; cell
Prior art date: 1990-07-20

Application number

FI913470A

Other languages

English (en)

Finnish (fi)

Swedish (sv)

Other versions

FI913470A0 (fi

FI913470L (fi

Inventor

Jeffrey M Greve

Alan Mcclelland

Original Assignee

Bayer Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-07-20

Filing date

1991-07-18

Publication date

2000-09-29

1991-07-18 Application filed by Bayer Ag filed Critical Bayer Ag

1991-07-18 Publication of FI913470A0 publication Critical patent/FI913470A0/fi

1992-01-21 Publication of FI913470L publication Critical patent/FI913470L/fi

2000-09-29 Application granted granted Critical

2000-09-29 Publication of FI105687B publication Critical patent/FI105687B/fi

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HEGSGKPQLMEBJL-RKQHYHRCSA-N octyl beta-D-glucopyranoside Chemical compound CCCCCCCCO[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O HEGSGKPQLMEBJL-RKQHYHRCSA-N 0.000 description 1
210000001672 ovary Anatomy 0.000 description 1
230000036961 partial effect Effects 0.000 description 1
239000002245 particle Substances 0.000 description 1
238000003359 percent control normalization Methods 0.000 description 1
230000035699 permeability Effects 0.000 description 1
239000008194 pharmaceutical composition Substances 0.000 description 1
COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 description 1
229920003023 plastic Polymers 0.000 description 1
239000004033 plastic Substances 0.000 description 1
238000002264 polyacrylamide gel electrophoresis Methods 0.000 description 1
229920001223 polyethylene glycol Polymers 0.000 description 1
229920001184 polypeptide Polymers 0.000 description 1
239000013641 positive control Substances 0.000 description 1
238000011533 pre-incubation Methods 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
230000037452 priming Effects 0.000 description 1
230000002285 radioactive effect Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
230000002441 reversible effect Effects 0.000 description 1
239000000523 sample Substances 0.000 description 1
238000003345 scintillation counting Methods 0.000 description 1
238000012216 screening Methods 0.000 description 1
230000003248 secreting effect Effects 0.000 description 1
238000004062 sedimentation Methods 0.000 description 1
230000035945 sensitivity Effects 0.000 description 1
238000001179 sorption measurement Methods 0.000 description 1
125000006850 spacer group Chemical group 0.000 description 1
210000004989 spleen cell Anatomy 0.000 description 1
238000007447 staining method Methods 0.000 description 1
239000005720 sucrose Substances 0.000 description 1
238000012360 testing method Methods 0.000 description 1
238000002560 therapeutic procedure Methods 0.000 description 1
238000009482 thermal adhesion granulation Methods 0.000 description 1
229910052719 titanium Inorganic materials 0.000 description 1
238000000844 transformation Methods 0.000 description 1
230000009466 transformation Effects 0.000 description 1
108091005703 transmembrane proteins Proteins 0.000 description 1
102000035160 transmembrane proteins Human genes 0.000 description 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 1
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210000002845 virion Anatomy 0.000 description 1
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Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70525—ICAM molecules, e.g. CD50, CD54, CD102
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Immunology (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Biophysics (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Toxicology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Plant Pathology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Physics & Mathematics (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
Communicable Diseases (AREA)
Microbiology (AREA)
Virology (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

FI913470A 1990-07-20 1991-07-18 Menetelmä terapeuttisesti käyttökelpoisen rhinoviruksen reseptoriproteiinin multimeerin valmistamiseksi FI105687B (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US55623890A	1990-07-20	1990-07-20
US55623890		1990-07-20

Publications (3)

Publication Number	Publication Date
FI913470A0 FI913470A0 (fi)	1991-07-18
FI913470L FI913470L (fi)	1992-01-21
FI105687B true FI105687B (fi)	2000-09-29

Family

ID=24220489

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI913470A FI105687B (fi)	1990-07-20	1991-07-18	Menetelmä terapeuttisesti käyttökelpoisen rhinoviruksen reseptoriproteiinin multimeerin valmistamiseksi

Country Status (14)

Country	Link
US (1)	US6096862A (fr)
EP (2)	EP0987329A3 (fr)
JP (1)	JP3091527B2 (fr)
KR (1)	KR100208847B1 (fr)
AT (1)	ATE184049T1 (fr)
DE (1)	DE69131564T2 (fr)
DK (1)	DK0468257T3 (fr)
ES (1)	ES2134762T3 (fr)
FI (1)	FI105687B (fr)
GR (1)	GR3031768T3 (fr)
IE (1)	IE912552A1 (fr)
IL (1)	IL98866A0 (fr)
PT (1)	PT98394B (fr)
ZA (1)	ZA915678B (fr)

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1991
- 1991-07-06 ES ES91111272T patent/ES2134762T3/es not_active Expired - Lifetime
- 1991-07-06 DE DE69131564T patent/DE69131564T2/de not_active Expired - Lifetime
- 1991-07-06 AT AT91111272T patent/ATE184049T1/de not_active IP Right Cessation
- 1991-07-06 DK DK91111272T patent/DK0468257T3/da active
- 1991-07-06 EP EP98124642A patent/EP0987329A3/fr not_active Withdrawn
- 1991-07-06 EP EP91111272A patent/EP0468257B1/fr not_active Expired - Lifetime
- 1991-07-17 IL IL98866A patent/IL98866A0/xx unknown
- 1991-07-18 FI FI913470A patent/FI105687B/fi not_active IP Right Cessation
- 1991-07-18 JP JP03202211A patent/JP3091527B2/ja not_active Expired - Lifetime
- 1991-07-19 PT PT98394A patent/PT98394B/pt not_active IP Right Cessation
- 1991-07-19 ZA ZA915678A patent/ZA915678B/xx unknown
- 1991-07-19 IE IE255291A patent/IE912552A1/en not_active IP Right Cessation
- 1991-07-20 KR KR1019910012433A patent/KR100208847B1/ko not_active Expired - Lifetime
1994
- 1994-10-04 US US08/318,039 patent/US6096862A/en not_active Expired - Lifetime
1999
- 1999-11-05 GR GR990402859T patent/GR3031768T3/el unknown

Also Published As

Publication number	Publication date
ZA915678B (en)	1992-05-27
IE912552A1 (en)	1992-01-29
ES2134762T3 (es)	1999-10-16
AU652567B2 (en)	1994-09-01
KR930002511A (ko)	1993-02-23
EP0468257A1 (fr)	1992-01-29
EP0468257B1 (fr)	1999-09-01
JP3091527B2 (ja)	2000-09-25
DE69131564T2 (de)	2000-01-13
DK0468257T3 (da)	2000-03-27
EP0987329A3 (fr)	2004-03-03
IL98866A0 (en)	1992-07-15
PT98394A (pt)	1992-06-30
AU8117691A (en)	1992-01-23
FI913470A0 (fi)	1991-07-18
DE69131564D1 (de)	1999-10-07
PT98394B (pt)	1999-01-29
GR3031768T3 (en)	2000-02-29
FI913470L (fi)	1992-01-21
ATE184049T1 (de)	1999-09-15
US6096862A (en)	2000-08-01
JPH04297499A (ja)	1992-10-21
EP0987329A2 (fr)	2000-03-22
KR100208847B1 (ko)	1999-07-15

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Date	Code	Title	Description
1995-09-27	GB	Transfer or assigment of application	Owner name: BAYER CORPORATION
2006-01-31	MA	Patent expired

Publication	Publication Date	Title
FI105687B (fi)	2000-09-29	Menetelmä terapeuttisesti käyttökelpoisen rhinoviruksen reseptoriproteiinin multimeerin valmistamiseksi
JP3520272B2 (ja)	2004-04-19	リンパ球機能関連抗原３のｃｄ２結合ドメイン
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US6458360B1 (en)	2002-10-01	Soluble complement regulatory molecules
JP3134874B2 (ja)	2001-02-13	Ｔ細胞表面タンパク質ｔ４をコードするｄｎａ並びにｔ４フラグメントのａｉｄｓ治療への使用
EP0391088B1 (fr)	1997-01-02	Utilisation de dérivés fonctionnels de la molécule d'adhésion intercellulaire ICAM-1 dans une thérapie anti-virale
US5686581A (en)	1997-11-11	Multimeric form of human rhinovirus receptor protein
JPH02503269A (ja)	1990-10-11	可溶性ｔ４の誘導体
AU2001278662A1 (en)	2002-05-02	NK cells activating receptors and their therapeutic and diagnostic uses
EP1301605A2 (fr)	2003-04-16	Recepteurs activant les cellules nk et leurs emplois therapeutiques et diagnostiques
JP3670276B2 (ja)	2005-07-13	ＣＤ４― ガンマ・２キメラ及びＣＤ４ ― ＩｇＧ２・キメラ
CA2122266A1 (fr)	1993-05-13	Peptides se liant au domaine de liaison cd8
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US6326004B1 (en)	2001-12-04	Antiviral methods using fragments of human rhinovirus receptor (ICAM-1)
US6107461A (en)	2000-08-22	Multimeric forms of human rhinovirus receptor and fragments thereof, and method of use
AU675441B2 (en)	1997-02-06	Multimeric forms of human rhinovirus receptor protein
US6143298A (en)	2000-11-07	Soluble truncated forms of ICAM-1
US6130202A (en)	2000-10-10	Antiviral methods
JPH02481A (ja)	1990-01-05	可溶性ｔ４の精製方法
AU710965B2 (en)	1999-09-30	Multimeric forms of human rhinovirus receptor protein
WO1995004756A1 (fr)	1995-02-16	Proteines inhibitrices complementaires de primates non humains
US20030211470A1 (en)	2003-11-13	CD4-IgG2-based salvage therapy of HIV-1 infection
JPH03504802A (ja)	1991-10-24	特定のウイルス感染に対する細胞毒性剤
HK1003104B (en)	1998-10-09	Use of functional derivatives of the intercellular adhesion molecule icam-1 in anti-viral therapy