DK0979237T3 - Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltrering - Google Patents
Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltreringInfo
- Publication number
- DK0979237T3 DK0979237T3 DK98908308T DK98908308T DK0979237T3 DK 0979237 T3 DK0979237 T3 DK 0979237T3 DK 98908308 T DK98908308 T DK 98908308T DK 98908308 T DK98908308 T DK 98908308T DK 0979237 T3 DK0979237 T3 DK 0979237T3
- Authority
- DK
- Denmark
- Prior art keywords
- nanofiltration
- protein solution
- log
- removing virus
- virus
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 241000700605 Viruses Species 0.000 title abstract 2
- 238000001728 nano-filtration Methods 0.000 title abstract 2
- 239000012460 protein solution Substances 0.000 title 1
- 241000701931 Canine parvovirus Species 0.000 abstract 1
- 241000709721 Hepatovirus A Species 0.000 abstract 1
- 239000012528 membrane Substances 0.000 abstract 1
- 244000309711 non-enveloped viruses Species 0.000 abstract 1
- 239000011148 porous material Substances 0.000 abstract 1
- 238000011045 prefiltration Methods 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 229940024790 prothrombin complex concentrate Drugs 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/145—Ultrafiltration
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6429—Thrombin (3.4.21.5)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21005—Thrombin (3.4.21.5)
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Water Supply & Treatment (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL1005332 | 1997-02-24 | ||
| EP97200533A EP0860444A1 (fr) | 1997-02-24 | 1997-02-24 | Méthode pour l'élimination de virus des solutions protéiques |
| EP98908308A EP0979237B1 (fr) | 1997-02-24 | 1998-02-23 | Procede d'elimination par nanofiltration des virus des solutions de proteine |
| PCT/NL1998/000108 WO1998037086A1 (fr) | 1997-02-24 | 1998-02-23 | Procede d'elimination par nanofiltration des virus d'une solution de proteine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0979237T3 true DK0979237T3 (da) | 2005-04-04 |
Family
ID=26146172
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98908308T DK0979237T3 (da) | 1997-02-24 | 1998-02-23 | Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltrering |
Country Status (6)
| Country | Link |
|---|---|
| EP (2) | EP0860444A1 (fr) |
| AT (1) | ATE283277T1 (fr) |
| DE (1) | DE69827787T2 (fr) |
| DK (1) | DK0979237T3 (fr) |
| ES (1) | ES2229481T3 (fr) |
| WO (1) | WO1998037086A1 (fr) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2772381B1 (fr) * | 1997-12-15 | 2001-06-08 | Lab Francais Du Fractionnement | Procede de preparation par filtration d'une solution de facteur viii securisee viralement |
| US7544500B2 (en) | 1999-11-13 | 2009-06-09 | Talecris Biotherapeutics, Inc. | Process for the production of a reversibly inactive acidified plasmin composition |
| US6355243B1 (en) | 1999-11-13 | 2002-03-12 | Bayer Corporation | Method of thrombolysis by local delivery of active plasmin |
| CN1192781C (zh) * | 1999-12-20 | 2005-03-16 | 三菱制药株式会社 | 用多孔膜处理的无病毒血浆蛋白组合物及其生产方法 |
| ES2214967B1 (es) | 2003-03-06 | 2005-06-16 | Probitas Pharma, S.A | Procedimiento para la eliminacion de virus en soluciones de fibrinogeno y fibrinogeno obtenido por dicho procedimiento. |
| US8258264B2 (en) | 2003-04-09 | 2012-09-04 | Juridical Foundation The Chemo-Sero-Therapeutic Research Institute | Process for producing albumin preparation |
| FR2861395B1 (fr) * | 2003-10-23 | 2006-02-17 | Lab Francais Du Fractionnement | Facteur viii viralement securise a faible teneur en multimeres superieurs |
| AU2012201036B2 (en) * | 2003-12-01 | 2014-12-04 | Novo Nordisk Health Care Ag | Virus filtration of liquid factor VII compositions |
| JP4874806B2 (ja) | 2003-12-01 | 2012-02-15 | ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト | 液体因子vii組成物のウイルス濾過 |
| EP1888208B1 (fr) * | 2004-10-21 | 2012-11-14 | Statens Serum Institut | Procede incluant la nanofiltration permettant d'obtenir un produit mbl resistant aux agents infectieux |
| ES2775974T3 (es) * | 2006-06-26 | 2020-07-28 | Omrix Biopharmaceuticals Inc | Eliminación de virus por nanofiltración |
| ES2298096B1 (es) | 2008-01-08 | 2009-01-01 | Grifols, S.A. | Procedimiento para la obtencion de un concentrado de factor von willebrand o del complejo de factor viii/factor von willebrand y utilizacionde los mismos. |
| WO2009149199A2 (fr) | 2008-06-04 | 2009-12-10 | Talecris Biotherapeutics, Inc. | Composition, méthode et nécessaire pour la préparation de plasmine |
| US8546127B2 (en) | 2008-06-30 | 2013-10-01 | General Electric Company | Bacteria/RNA extraction device |
| US8158405B2 (en) | 2008-06-30 | 2012-04-17 | General Electric Company | Process for concentrating and processing fluid samples |
| PT2403865E (pt) | 2009-03-03 | 2015-11-18 | Grifols Therapeutics Inc | Métodos de preparação de plasminogénio |
| AU2012304763A1 (en) | 2011-09-06 | 2014-03-06 | Medimmune Llc | Methods for processing coagulation factors |
| CN112978859A (zh) * | 2021-04-13 | 2021-06-18 | 莱特莱德(上海)技术有限公司 | 一种提取肝素加工废水中肠膜肽的方法 |
| CN116983835B (zh) * | 2023-09-28 | 2024-01-09 | 杭州华玮生物科技有限公司 | 一种高强度纤维素除病毒过滤膜及其制备方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9500724D0 (sv) * | 1994-06-23 | 1995-02-24 | Pharmacia Ab | Filtrering |
| US5677162A (en) * | 1995-05-01 | 1997-10-14 | New York Blood Center, Inc. | Method for activating prothrombin to thrombin |
-
1997
- 1997-02-24 EP EP97200533A patent/EP0860444A1/fr not_active Withdrawn
-
1998
- 1998-02-23 ES ES98908308T patent/ES2229481T3/es not_active Expired - Lifetime
- 1998-02-23 WO PCT/NL1998/000108 patent/WO1998037086A1/fr not_active Ceased
- 1998-02-23 DK DK98908308T patent/DK0979237T3/da active
- 1998-02-23 EP EP98908308A patent/EP0979237B1/fr not_active Revoked
- 1998-02-23 DE DE69827787T patent/DE69827787T2/de not_active Revoked
- 1998-02-23 AT AT98908308T patent/ATE283277T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0979237A1 (fr) | 2000-02-16 |
| WO1998037086A1 (fr) | 1998-08-27 |
| DE69827787T2 (de) | 2006-03-02 |
| EP0860444A1 (fr) | 1998-08-26 |
| EP0979237B1 (fr) | 2004-11-24 |
| ES2229481T3 (es) | 2005-04-16 |
| DE69827787D1 (de) | 2004-12-30 |
| ATE283277T1 (de) | 2004-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0979237T3 (da) | Fremgangsmåde til fjernelse af virus fra proteinoplösning ved nanofiltrering | |
| MX9701183A (es) | Procedimiento de preparacion del virus gripal, antigenos obtenidos y sus aplicaciones. | |
| ATE346861T1 (de) | Verfahren zur reinigung und isolierung von viren, aus pflanzenquellen | |
| DK0891420T3 (da) | Fremgangsmåde til replikation af influenzavirus i cellekultur samt de ved fremgangsmåden opnåelige influenzavirus | |
| AU696246B2 (en) | Process for the sterilization of biological compositions and the product produced thereby | |
| AU5370598A (en) | Methods for purifying viruses | |
| SG156673A1 (en) | Improved viral purification methods | |
| JP4495404B2 (ja) | ナノろ過によってタンパク溶液からウイルスを分離する方法 | |
| DE50109784D1 (de) | Stabilisiertes Protein-Präparat und Verfahren zu seiner Herstellung | |
| DK0702085T3 (da) | Rekombinant infektiøs ikke-segmenteret negativ-strenget RNA-virus | |
| ES2101077T3 (es) | Procedimiento para la inactivacion de priones. | |
| PT88178A (pt) | Metodo para a purificacao de virus da hepatite a | |
| DE69721840D1 (en) | Zuckerrohr bacilliformviruspromotor | |
| Schlegel et al. | Virus inactivation of plasma‐derived proteins by pasteurization in the presence of guanidine hydrochloride | |
| DK0480949T3 (da) | Fremstilling af virus og oprensning af virale kappeproteiner til vaccineanvendelse | |
| CA2169122A1 (fr) | Elimination des virus dans des solutions proteiniques, par ultrafiltration | |
| JPH11286453A (ja) | 紫外線照射によるタンパク質含有組成物のウイルス不活化処理方法 | |
| ES2196870T3 (es) | Procedimiento para la purificacion o aislamiento de acidos nucleicos virales. | |
| DE60229805D1 (de) | Nukleinsäurereinigung | |
| ATE179428T1 (de) | Verfahren zur herstellung von hepatitis antigenen und impfstoffen | |
| Van Holten et al. | Incorporation of an additional viral‐clearance step into a human immunoglobulin manufacturing process | |
| DE69125066D1 (de) | cDNS-Sequenz und Detektion des Hepatitis C-Virus | |
| DK0776212T3 (da) | Fremgangsmåde til fremstilling af infektionsfri farmaceutiske præparater og/eller næringsmidler ud fra infektiøst materiale | |
| DE59813486D1 (de) | Verfahren zur Herstellung von Blutplasmaprodukten durch Ausschluss von Spenden mit hohen Parvo-B19-Virenkonzentrationen | |
| US20040000482A1 (en) | Viral removal |