DK1051500T3 - Diagnose og behandling af AUR1- og/eller AUR2-relaterede sygdomme - Google Patents
Diagnose og behandling af AUR1- og/eller AUR2-relaterede sygdommeInfo
- Publication number
- DK1051500T3 DK1051500T3 DK99905450T DK99905450T DK1051500T3 DK 1051500 T3 DK1051500 T3 DK 1051500T3 DK 99905450 T DK99905450 T DK 99905450T DK 99905450 T DK99905450 T DK 99905450T DK 1051500 T3 DK1051500 T3 DK 1051500T3
- Authority
- DK
- Denmark
- Prior art keywords
- aur1
- aur2
- polypeptides
- diagnosis
- treatment
- Prior art date
Links
- 101150064299 AUR1 gene Proteins 0.000 title abstract 5
- 101100381333 Arabidopsis thaliana AUR2 gene Proteins 0.000 title abstract 5
- 101100297762 Gibberella zeae (strain ATCC MYA-4620 / CBS 123657 / FGSC 9075 / NRRL 31084 / PH-1) PKS12 gene Proteins 0.000 title abstract 5
- 238000003745 diagnosis Methods 0.000 title abstract 2
- 201000010099 disease Diseases 0.000 title abstract 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 2
- 238000011282 treatment Methods 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 102000039446 nucleic acids Human genes 0.000 abstract 2
- 108020004707 nucleic acids Proteins 0.000 abstract 2
- 150000007523 nucleic acids Chemical class 0.000 abstract 2
- 241001465754 Metazoa Species 0.000 abstract 1
- 230000002159 abnormal effect Effects 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/48—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
- C12Q1/485—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase involving kinase
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
- G01N2500/10—Screening for compounds of potential therapeutic value involving cells
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/012,135 US6716575B2 (en) | 1995-12-18 | 1998-01-22 | Diagnosis and treatment of AUR1 and/or AUR2 related disorders |
| PCT/US1999/001283 WO1999037788A2 (en) | 1998-01-22 | 1999-01-21 | Diagnosis and treatment of aur1 and/or aur2 related disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1051500T3 true DK1051500T3 (da) | 2005-12-19 |
Family
ID=21753554
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK99905450T DK1051500T3 (da) | 1998-01-22 | 1999-01-21 | Diagnose og behandling af AUR1- og/eller AUR2-relaterede sygdomme |
Country Status (11)
| Country | Link |
|---|---|
| US (3) | US6716575B2 (de) |
| EP (1) | EP1051500B1 (de) |
| JP (1) | JP2002508937A (de) |
| AT (1) | ATE302278T1 (de) |
| AU (1) | AU2560599A (de) |
| CA (1) | CA2318352A1 (de) |
| CY (1) | CY1105446T1 (de) |
| DE (1) | DE69926731T2 (de) |
| DK (1) | DK1051500T3 (de) |
| ES (1) | ES2247783T3 (de) |
| WO (1) | WO1999037788A2 (de) |
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| EP0586608A1 (de) | 1991-05-29 | 1994-03-16 | Pfizer Inc. | Tricyclische polyhydroxy tyrosin-kinase-inhibitoren |
| NZ243082A (en) | 1991-06-28 | 1995-02-24 | Ici Plc | 4-anilino-quinazoline derivatives; pharmaceutical compositions, preparatory processes, and use thereof |
| US5298422A (en) | 1991-11-06 | 1994-03-29 | Baylor College Of Medicine | Myogenic vector systems |
| AU661533B2 (en) | 1992-01-20 | 1995-07-27 | Astrazeneca Ab | Quinazoline derivatives |
| GB9205320D0 (en) | 1992-03-11 | 1992-04-22 | Ici Plc | Anti-tumour compounds |
| WO1994003427A1 (en) | 1992-08-06 | 1994-02-17 | Warner-Lambert Company | 2-thioindoles (selenoindoles) and related disulfides (selenides) which inhibit protein tyrosine kinases and which have antitumor properties |
| US5330992A (en) | 1992-10-23 | 1994-07-19 | Sterling Winthrop Inc. | 1-cyclopropyl-4-pyridyl-quinolinones |
| GB9226855D0 (en) | 1992-12-23 | 1993-02-17 | Erba Carlo Spa | Vinylene-azaindole derivatives and process for their preparation |
| US5958721A (en) | 1993-04-07 | 1999-09-28 | Cancer Research Campaign Technology, Ltd. | Methods for screening of substances for therapeutic activity and yeast for use therein |
| GB9501567D0 (en) | 1995-01-26 | 1995-03-15 | Pharmacia Spa | Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors |
| US5830648A (en) | 1995-05-05 | 1998-11-03 | Sugen, Inc. | Assay and method for transcript imaging |
| EP1655369A1 (de) | 1995-12-18 | 2006-05-10 | Sugen, Inc. | Diagnose und Behandlung von mit AUR-1 und/oder AUR-2 assoziierten Krankeheiten |
-
1998
- 1998-01-22 US US09/012,135 patent/US6716575B2/en not_active Expired - Lifetime
-
1999
- 1999-01-21 JP JP2000528695A patent/JP2002508937A/ja active Pending
- 1999-01-21 DE DE69926731T patent/DE69926731T2/de not_active Expired - Lifetime
- 1999-01-21 AU AU25605/99A patent/AU2560599A/en not_active Abandoned
- 1999-01-21 AT AT99905450T patent/ATE302278T1/de active
- 1999-01-21 EP EP99905450A patent/EP1051500B1/de not_active Expired - Lifetime
- 1999-01-21 WO PCT/US1999/001283 patent/WO1999037788A2/en not_active Ceased
- 1999-01-21 CA CA002318352A patent/CA2318352A1/en not_active Abandoned
- 1999-01-21 ES ES99905450T patent/ES2247783T3/es not_active Expired - Lifetime
- 1999-01-21 DK DK99905450T patent/DK1051500T3/da active
- 1999-03-31 US US09/283,011 patent/US6207401B1/en not_active Expired - Lifetime
-
2001
- 2001-02-16 US US09/784,332 patent/US6841579B1/en not_active Expired - Lifetime
-
2005
- 2005-11-15 CY CY20051101394T patent/CY1105446T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| US20050002938A1 (en) | 2005-01-06 |
| EP1051500A2 (de) | 2000-11-15 |
| CY1105446T1 (el) | 2010-04-28 |
| CA2318352A1 (en) | 1999-07-29 |
| US6207401B1 (en) | 2001-03-27 |
| US20020081578A1 (en) | 2002-06-27 |
| JP2002508937A (ja) | 2002-03-26 |
| WO1999037788A3 (en) | 1999-09-30 |
| WO1999037788A9 (en) | 1999-11-04 |
| EP1051500B1 (de) | 2005-08-17 |
| US6716575B2 (en) | 2004-04-06 |
| WO1999037788A2 (en) | 1999-07-29 |
| DE69926731D1 (de) | 2005-09-22 |
| ES2247783T3 (es) | 2006-03-01 |
| ATE302278T1 (de) | 2005-09-15 |
| AU2560599A (en) | 1999-08-09 |
| DE69926731T2 (de) | 2006-05-18 |
| US6841579B1 (en) | 2005-01-11 |
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