DK1137768T3 - Human hybrid værtscelle til pattedyrgenekspression - Google Patents

Human hybrid værtscelle til pattedyrgenekspression

Info

Publication number
DK1137768T3
DK1137768T3 DK99963067T DK99963067T DK1137768T3 DK 1137768 T3 DK1137768 T3 DK 1137768T3 DK 99963067 T DK99963067 T DK 99963067T DK 99963067 T DK99963067 T DK 99963067T DK 1137768 T3 DK1137768 T3 DK 1137768T3
Authority
DK
Denmark
Prior art keywords
cells
human
recombinant
gene expression
mammalian gene
Prior art date
Application number
DK99963067T
Other languages
English (en)
Inventor
Myung-Sam Cho
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK1137768T3 publication Critical patent/DK1137768T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/10—Cells modified by introduction of foreign genetic material
    • C12N5/12—Fused cells, e.g. hybridomas
    • C12N5/16—Animal cells
    • C12N5/163—Animal cells one of the fusion partners being a B or a T lymphocyte
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
DK99963067T 1998-12-10 1999-12-08 Human hybrid værtscelle til pattedyrgenekspression DK1137768T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/209,920 US6136599A (en) 1998-12-10 1998-12-10 Human hybrid host cell for mammalian gene expression
PCT/US1999/029332 WO2000034462A1 (en) 1998-12-10 1999-12-08 Human hybrid host cell for mammalian gene expression

Publications (1)

Publication Number Publication Date
DK1137768T3 true DK1137768T3 (da) 2005-12-19

Family

ID=22780882

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99963067T DK1137768T3 (da) 1998-12-10 1999-12-08 Human hybrid værtscelle til pattedyrgenekspression

Country Status (27)

Country Link
US (1) US6136599A (da)
EP (1) EP1137768B1 (da)
JP (3) JP4332300B2 (da)
KR (1) KR100627753B1 (da)
CN (1) CN1230532C (da)
AT (1) ATE306547T1 (da)
AU (1) AU757188B2 (da)
BG (1) BG65263B1 (da)
BR (1) BRPI9916095B8 (da)
CA (1) CA2353698C (da)
CU (2) CU23382A3 (da)
CZ (1) CZ302677B6 (da)
DE (1) DE69927707T2 (da)
DK (1) DK1137768T3 (da)
ES (1) ES2249929T3 (da)
HU (1) HU229775B1 (da)
ID (1) ID30448A (da)
IL (2) IL143351A0 (da)
NO (1) NO330548B1 (da)
PL (1) PL205549B1 (da)
RO (1) RO121563B1 (da)
RU (1) RU2228355C2 (da)
SI (1) SI20693B (da)
SK (1) SK287888B6 (da)
TR (1) TR200101642T2 (da)
UA (1) UA77642C2 (da)
WO (1) WO2000034462A1 (da)

Families Citing this family (26)

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Publication number Priority date Publication date Assignee Title
US6136599A (en) * 1998-12-10 2000-10-24 Bayer Corporation Human hybrid host cell for mammalian gene expression
US6358703B1 (en) 1998-12-10 2002-03-19 Bayer Corporation Expression system for factor VIII
US6348192B1 (en) * 1999-05-11 2002-02-19 Bayer Corporation Interleukin-2 mutein expressed from mammalian cells
US20040235715A1 (en) * 1999-11-12 2004-11-25 Bayer Corporation Method of producing glycosylated bikunin
US7094587B2 (en) * 2000-06-27 2006-08-22 Millennium Pharmaceuticals, Inc. 16002 Molecules and uses therefor
US6569657B1 (en) * 2000-06-27 2003-05-27 Millennium Pharmaceuticals, Inc. 32140, a novel human aldehyde dehydrogenase and uses therefor
US7723102B2 (en) * 2000-09-28 2010-05-25 Bayer Corporation Enhanced transfection system
MY139948A (en) * 2000-09-28 2009-11-30 Bayer Corp Enhanced transfection system
US20060073141A1 (en) * 2001-06-28 2006-04-06 Domantis Limited Compositions and methods for treating inflammatory disorders
KR100496861B1 (ko) 2002-09-26 2005-06-22 삼성전자주식회사 하나의 핸들러에 2개 이상의 테스트 보드를 갖는 테스트장비 및 그 테스트 방법
DE60333228D1 (de) 2002-12-02 2010-08-12 Amgen Fremont Inc Gegen den tumor nekrose faktor gerichtete antikörper und deren verwendungen
US7244616B2 (en) 2003-06-27 2007-07-17 Bayer Pharmaceuticals Corporation Use of molecular chaperones for the enhanced production of secreted, recombinant proteins in mammalian cells
KR101468345B1 (ko) 2004-11-12 2014-12-03 바이엘 헬스케어 엘엘씨 Ｆｖｉｉｉ의 부위 지향 변형
WO2008149147A2 (en) 2007-06-06 2008-12-11 Domantis Limited Polypeptides, antibody variable domains and antagonists
JP5628790B2 (ja) 2008-04-07 2014-11-19 バイエル・ヘルスケア・エルエルシー 糖タンパク質の組換え生産の方法
KR101005967B1 (ko) * 2008-04-12 2011-01-05 (주)셀트리온 우수한 재조합 단백질을 생산하기 위한 인간 숙주 세포
US9090948B2 (en) 2008-09-30 2015-07-28 Abbott Molecular Inc. Primers and probes for detecting human papillomavirus and human beta globin sequences in test samples
EP2440653B1 (en) * 2009-06-10 2018-12-05 BTS Research International Pty Ltd Methods of generating hybrid/chimeric cells, and uses thereof
US11649449B2 (en) 2015-09-03 2023-05-16 CHO Plus, Inc. Hybrid cell lines for high level production of a target protein
EP3487998B1 (en) 2016-07-19 2023-07-12 Brandeis University Compositions and methods for identifying rna binding polypeptide targets
KR20210013090A (ko) 2018-05-16 2021-02-03 모르포시스 아게 당단백질 vi를 표적으로 하는 항체
CA3125527A1 (en) 2018-12-20 2020-06-25 Orionis Biosciences, Inc. Particle based small molecule-protein complex trap
MA55285A (fr) 2019-03-14 2022-01-19 Morphosys Ag Anticorps ciblant c5ar
BR112021024923A2 (pt) * 2019-06-10 2022-02-15 Cho Plus Inc Métodos de preparação de uma linha celular, de produção de um produto farmacêutico, de obtenção de uma linha celular e de produção de uma proteína, linhas celulares produtora e híbrida, sistema para produção de alto nível de produtos farmacêuticos, e, produto farmacêutico
US20230357398A1 (en) 2020-09-24 2023-11-09 Morphosys Ag Novel human antibodies binding to human cd3 epsilon
CN113604425B (zh) * 2021-06-22 2022-10-18 中山康天晟合生物技术有限公司 一种适应无血清培养基环境的wayne293 lvpro细胞及其应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6045849B2 (ja) * 1980-08-25 1985-10-12 林原 健 ヒトエリトロポエチンの製造方法
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
US6136599A (en) * 1998-12-10 2000-10-24 Bayer Corporation Human hybrid host cell for mammalian gene expression

Also Published As

Publication number Publication date
SK7912001A3 (en) 2002-03-05
ES2249929T3 (es) 2006-04-01
HUP0104681A2 (hu) 2002-04-29
JP2014131513A (ja) 2014-07-17
EP1137768A4 (en) 2002-09-18
JP4332300B2 (ja) 2009-09-16
AU757188B2 (en) 2003-02-06
BRPI9916095B1 (pt) 2015-10-13
BRPI9916095B8 (pt) 2021-05-25
CA2353698A1 (en) 2000-06-15
PL205549B1 (pl) 2010-04-30
EP1137768A1 (en) 2001-10-04
CZ20012023A3 (cs) 2001-10-17
CN1230532C (zh) 2005-12-07
JP2009148295A (ja) 2009-07-09
CU23382A3 (es) 2009-06-25
CU23238A1 (es) 2007-09-26
RU2228355C2 (ru) 2004-05-10
JP2002531125A (ja) 2002-09-24
KR20020002360A (ko) 2002-01-09
CA2353698C (en) 2012-02-21
US6136599A (en) 2000-10-24
BG65263B1 (bg) 2007-10-31
NO20012806L (no) 2001-06-07
BR9916095A (pt) 2001-09-04
SI20693B (sl) 2008-12-31
TR200101642T2 (tr) 2001-11-21
HUP0104681A3 (en) 2005-10-28
JP5508740B2 (ja) 2014-06-04
DE69927707D1 (de) 2006-02-23
WO2000034462A1 (en) 2000-06-15
RO121563B1 (ro) 2007-11-30
AU1938300A (en) 2000-06-26
KR100627753B1 (ko) 2006-09-26
ATE306547T1 (de) 2005-10-15
CN1339063A (zh) 2002-03-06
SI20693A (sl) 2002-04-30
ID30448A (id) 2001-12-06
DE69927707T2 (de) 2006-07-13
HU229775B1 (en) 2014-07-28
EP1137768B1 (en) 2005-10-12
IL143351A0 (en) 2002-04-21
NO20012806D0 (no) 2001-06-07
SK287888B6 (sk) 2012-03-02
NO330548B1 (no) 2011-05-16
BG105566A (en) 2002-03-29
UA77642C2 (en) 2007-01-15
CZ302677B6 (cs) 2011-08-31
JP5826311B2 (ja) 2015-12-02
IL143351A (en) 2009-12-24

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