DK164407B - Modificerede nucleotider og fremgangsmaader til deres fremstilling, fremgangsmaade til paavisning af et dobbeltstrenget polynucleotidduplex indeholdende et modificeret nucleotid, fremgangsmaade til bestemmelse af tilstedevaerelsen af et deoxyribonucleinsyremolekyle eller et ribonucleinsyremolekyle, fremgangsmaade til test af en bakterie, fremgangsmaade til diagnosticering af en genetisk forstyrrelse, fre - Google Patents
Modificerede nucleotider og fremgangsmaader til deres fremstilling, fremgangsmaade til paavisning af et dobbeltstrenget polynucleotidduplex indeholdende et modificeret nucleotid, fremgangsmaade til bestemmelse af tilstedevaerelsen af et deoxyribonucleinsyremolekyle eller et ribonucleinsyremolekyle, fremgangsmaade til test af en bakterie, fremgangsmaade til diagnosticering af en genetisk forstyrrelse, fre Download PDFInfo
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- DK164407B DK164407B DK171382A DK171382A DK164407B DK 164407 B DK164407 B DK 164407B DK 171382 A DK171382 A DK 171382A DK 171382 A DK171382 A DK 171382A DK 164407 B DK164407 B DK 164407B
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
- C12Q1/18—Testing for antimicrobial activity of a material
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/26—Preparation of nitrogen-containing carbohydrates
- C12P19/28—N-glycosides
- C12P19/30—Nucleotides
- C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6804—Nucleic acid analysis using immunogens
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Pathology (AREA)
- Saccharide Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US25522381A | 1981-04-17 | 1981-04-17 | |
| US25522381 | 1981-04-17 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK171382A DK171382A (da) | 1982-10-18 |
| DK164407B true DK164407B (da) | 1992-06-22 |
Family
ID=22967380
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK171382A DK164407B (da) | 1981-04-17 | 1982-04-16 | Modificerede nucleotider og fremgangsmaader til deres fremstilling, fremgangsmaade til paavisning af et dobbeltstrenget polynucleotidduplex indeholdende et modificeret nucleotid, fremgangsmaade til bestemmelse af tilstedevaerelsen af et deoxyribonucleinsyremolekyle eller et ribonucleinsyremolekyle, fremgangsmaade til test af en bakterie, fremgangsmaade til diagnosticering af en genetisk forstyrrelse, fre |
| DK160591A DK171822B1 (da) | 1981-04-17 | 1991-09-16 | Modificerede nucleotider og fremgangsmåder til deres fremstilling og påvisning |
| DK046797A DK46797A (da) | 1981-04-17 | 1997-04-28 | Modificerede oligo- og polynucleotider og fremgangsmåder til deres fremstilling og påvisning |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK160591A DK171822B1 (da) | 1981-04-17 | 1991-09-16 | Modificerede nucleotider og fremgangsmåder til deres fremstilling og påvisning |
| DK046797A DK46797A (da) | 1981-04-17 | 1997-04-28 | Modificerede oligo- og polynucleotider og fremgangsmåder til deres fremstilling og påvisning |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP0063879B1 (de) |
| JP (6) | JPS57209297A (de) |
| AT (1) | ATE167189T1 (de) |
| AU (1) | AU560651B2 (de) |
| CA (1) | CA1219824A (de) |
| DE (2) | DE3280032D1 (de) |
| DK (3) | DK164407B (de) |
| IL (1) | IL65447A (de) |
Families Citing this family (190)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1219824A (en) * | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
| FI63596C (fi) * | 1981-10-16 | 1983-07-11 | Orion Yhtymae Oy | Mikrobdiagnostiskt foerfarande som grundar sig pao skiktshybridisering av nukleinsyror och vid foerfarandet anvaenda kombinationer av reagenser |
| DK105582A (da) * | 1982-03-11 | 1983-09-12 | Nordisk Insulinlab | Fremgangsmaade til bestemmelse af humane hla-d(r) vaevstyper og gensonde til brug ved fremgangsmaaden |
| US7220854B1 (en) | 1982-06-23 | 2007-05-22 | Enzo Life Sciences, Inc. C/O Enzo Biochem, Inc. | Sugar moiety labeled nucleotide, and an oligo- or polynucleotide, and other compositions comprising such sugar moiety labeled nucleotides |
| US5241060A (en) * | 1982-06-23 | 1993-08-31 | Enzo Diagnostics, Inc. | Base moiety-labeled detectable nucleatide |
| CA1223831A (en) | 1982-06-23 | 1987-07-07 | Dean Engelhardt | Modified nucleotides, methods of preparing and utilizing and compositions containing the same |
| US5260433A (en) * | 1982-06-23 | 1993-11-09 | Enzo Diagnostics, Inc. | Saccharide specific binding system labeled nucleotides |
| EP0148356B1 (de) * | 1982-09-30 | 1990-12-05 | Aktiebolaget Iro | Garnspeicher- und Zuführvorrichtung |
| US4689295A (en) * | 1983-01-20 | 1987-08-25 | Integrated Genetics, Inc. | Test for Salmonella |
| US4994373A (en) | 1983-01-27 | 1991-02-19 | Enzo Biochem, Inc. | Method and structures employing chemically-labelled polynucleotide probes |
| FR2540122B1 (fr) * | 1983-01-27 | 1985-11-29 | Centre Nat Rech Scient | Nouveaux composes comportant une sequence d'oligonucleotide liee a un agent d'intercalation, leur procede de synthese et leur application |
| CA1309672C (en) * | 1983-01-27 | 1992-11-03 | Jannis G. Stavrianopoulos | Methods and structures employing non-radioactive chemically-labeled polynucleotide probes |
| US4605735A (en) * | 1983-02-14 | 1986-08-12 | Wakunaga Seiyaku Kabushiki Kaisha | Oligonucleotide derivatives |
| JPS59148798A (ja) * | 1983-02-14 | 1984-08-25 | Wakunaga Seiyaku Kk | ビオチンヌクレオチド誘導体 |
| US4948882A (en) * | 1983-02-22 | 1990-08-14 | Syngene, Inc. | Single-stranded labelled oligonucleotides, reactive monomers and methods of synthesis |
| EP0135587B2 (de) * | 1983-02-22 | 2002-12-18 | Syngene, Inc. | Einzelstrang-oligonukleotide bestimmter sequenz, markergruppen enthaltend, verfahren zu deren chemischer synthese und nukleotide zur verwendung darin |
| CA1254525A (en) * | 1983-04-13 | 1989-05-23 | Christine L. Brakel | Kit for terminally chemically labeling dna |
| ES8600404A1 (es) * | 1983-05-02 | 1985-10-01 | Enzo Biochem Inc | Un metodo para detectar una secuencia seleccionada de acido nucleico en un material biologico. |
| CA1228811A (en) * | 1983-05-05 | 1987-11-03 | Robert G. Pergolizzi | Assay method utilizing polynucleotide sequences |
| DE3485811T2 (de) * | 1983-05-31 | 1993-01-07 | Orgenics Ltd | Molekulare genetische sonde und verfahren zu ihrer herstellung, testmethode und satz in denen diese molekulare genetische sonde gebraucht wird. |
| US5221609A (en) * | 1983-05-31 | 1993-06-22 | Orgenics Ltd. | Molecular genetic probe, and method of forming same, assay technique and kit using said molecular genetic probe |
| CA1222705A (en) * | 1983-07-14 | 1987-06-09 | Molecular Diagnostics, Inc. | Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays |
| US4959309A (en) * | 1983-07-14 | 1990-09-25 | Molecular Diagnostics, Inc. | Fast photochemical method of labelling nucleic acids for detection purposes in hybridization assays |
| US4623627A (en) | 1983-08-19 | 1986-11-18 | Cetus Corporation | Monoclonal antibody having specificity for the double-stranded conformation of native DNA and diagnostic methods using same |
| NO843838L (no) * | 1983-09-26 | 1985-03-27 | Ortho Diagnostic Systems Inc | Fremgangsmaate for detektering av nukleinsyre |
| FR2555606B1 (fr) * | 1983-11-24 | 1986-10-24 | Pasteur Institut | Sonde non radio-active et procede pour la caracterisation d'une sequence nucleotidique determinee et moyens pour la production de cette sonde non radio-active |
| WO1985002415A1 (fr) * | 1983-11-24 | 1985-06-06 | Institut Pasteur | Sonde non radioactive et procede pour la caracterisation d'une sequence nucleotidique determinee et moyens pour la production de cette sonde non radioactive |
| IL73580A0 (en) * | 1983-12-12 | 1985-02-28 | Miles Lab | Hybridization assay employing labeled pairs of hybrid binding reagents |
| EP0144913A3 (de) * | 1983-12-12 | 1986-08-20 | Miles Inc. | Hybridisierungstest mittels einer markierten Probe und Anti-Hybrid |
| IL73578A (en) * | 1983-12-12 | 1989-09-28 | Miles Lab | Method and reagent for the detection of polynucleotide sequence in sample of dna or rna by using a nucleic acid probe and contact of duplexes with immobilizing antibody |
| EP0144914A3 (de) * | 1983-12-12 | 1986-08-13 | Miles Inc. | Hybridisierungstest mittels markierter Paare von hybridbindenden Reagenzien |
| EP0146039A3 (de) * | 1983-12-12 | 1986-08-27 | Miles Inc. | Hybridisierungstest mit Immobilisierung von Hybriden mittels Antihybridbindung |
| US4743535A (en) * | 1984-11-07 | 1988-05-10 | Miles Inc. | Hybridization assay employing labeled probe and anti-hybrid |
| EP0149339B1 (de) * | 1983-12-16 | 1989-08-23 | MediSense, Inc. | Test für Nukleinsäuren |
| US4849513A (en) * | 1983-12-20 | 1989-07-18 | California Institute Of Technology | Deoxyribonucleoside phosphoramidites in which an aliphatic amino group is attached to the sugar ring and their use for the preparation of oligonucleotides containing aliphatic amino groups |
| JPH0690200B2 (ja) * | 1984-01-16 | 1994-11-14 | カリフオルニア・インステイテユ−ト・オブ・テクノロジ− | オリゴヌクレオチドの分析法 |
| US5821058A (en) * | 1984-01-16 | 1998-10-13 | California Institute Of Technology | Automated DNA sequencing technique |
| USRE43096E1 (en) | 1984-01-16 | 2012-01-10 | California Institute Of Technology | Tagged extendable primers and extension products |
| US4699876A (en) * | 1984-01-27 | 1987-10-13 | E. I. Du Pont De Nemours And Company | Nonradiometric polynucleotide probes |
| EP0170652A4 (de) * | 1984-01-27 | 1988-08-23 | Molecular Biosystems Inc | Test für immobilisierte reportergruppen. |
| US4849505A (en) * | 1984-01-30 | 1989-07-18 | Enzo Biochem, Inc. | Detectable molecules, method of preparation and use |
| US4849208A (en) * | 1984-01-30 | 1989-07-18 | Enzo Biochem, Inc. | Detectable molecules, method of preparation and use |
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| US4843122A (en) * | 1984-01-30 | 1989-06-27 | Enzo Biochem, Inc. | Detectable molecules, method of preparation and use |
| AU3844485A (en) * | 1984-02-09 | 1985-08-15 | Enzo Biochem Inc. | Heterologous detection of cabeled dna |
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| US4582789A (en) * | 1984-03-21 | 1986-04-15 | Cetus Corporation | Process for labeling nucleic acids using psoralen derivatives |
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| US4803297A (en) * | 1984-03-21 | 1989-02-07 | Cetus Corporation | Carbamic acid ester useful for preparing a nucleic acid probe |
| CA1260372A (en) * | 1984-04-27 | 1989-09-26 | Elazar Rabbani | Hybridization method for the detection of genetic materials |
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| CA1253777A (en) * | 1984-06-01 | 1989-05-09 | Robert J. Carrico | Nucleic acid hybridization assay employing immobilized rna probes |
| JP2648082B2 (ja) * | 1984-06-28 | 1997-08-27 | 株式会社日立製作所 | 核酸塩基検出方法 |
| JPH0658368B2 (ja) * | 1984-06-28 | 1994-08-03 | 株式会社日立製作所 | 核酸塩基検出装置 |
| FR2567523B1 (fr) * | 1984-07-12 | 1987-11-13 | Pasteur Institut | Polynucleotides lies de facon covalente a un support solide, et procede pour leur obtention |
| DE3431536A1 (de) * | 1984-08-28 | 1986-03-13 | Boehringer Mannheim Gmbh, 6800 Mannheim | Derivatisierte nucleinsaeure-sequenz, verfahren zu deren herstellung sowie deren verwendung zum nachweis von nucleinsaeuren |
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| US4828979A (en) * | 1984-11-08 | 1989-05-09 | Life Technologies, Inc. | Nucleotide analogs for nucleic acid labeling and detection |
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Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN142734B (de) * | 1975-04-28 | 1977-08-20 | Miles Lab | |
| CA1219824A (en) * | 1981-04-17 | 1987-03-31 | David C. Ward | Modified nucleotides and methods of preparing and using same |
| FR2519004B1 (fr) * | 1981-12-29 | 1985-09-27 | Pasteur Institut | Acide adenosine 5'-triphosphorique modifie et procede de dosage de substances biologiques susceptibles de fixer des produits de degradation de l'acide adenosine 5'-triphosphorique |
| FR2519005B1 (fr) * | 1981-12-29 | 1985-10-25 | Pasteur Institut | Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn |
-
1982
- 1982-03-15 CA CA000398359A patent/CA1219824A/en not_active Expired
- 1982-04-06 IL IL65447A patent/IL65447A/xx unknown
- 1982-04-06 DE DE8282301804T patent/DE3280032D1/de not_active Expired
- 1982-04-06 EP EP82301804A patent/EP0063879B1/de not_active Expired
- 1982-04-06 DE DE3280478T patent/DE3280478T2/de not_active Expired - Lifetime
- 1982-04-06 AT AT89106206T patent/ATE167189T1/de not_active IP Right Cessation
- 1982-04-13 AU AU82573/82A patent/AU560651B2/en not_active Expired
- 1982-04-16 DK DK171382A patent/DK164407B/da not_active IP Right Cessation
- 1982-04-16 JP JP57064611A patent/JPS57209297A/ja active Granted
-
1987
- 1987-04-03 JP JP62083703A patent/JPH0694474B2/ja not_active Expired - Lifetime
-
1990
- 1990-01-18 JP JP2010469A patent/JPH03261798A/ja active Pending
-
1991
- 1991-09-16 DK DK160591A patent/DK171822B1/da not_active IP Right Cessation
-
1992
- 1992-06-24 JP JP4166268A patent/JPH0880B2/ja not_active Expired - Lifetime
-
1997
- 1997-04-28 DK DK046797A patent/DK46797A/da not_active Application Discontinuation
- 1997-04-28 JP JP11100397A patent/JP3279503B2/ja not_active Expired - Lifetime
- 1997-04-28 JP JP11100297A patent/JP3279502B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS57209297A (en) | 1982-12-22 |
| AU8257382A (en) | 1982-10-21 |
| JP3279502B2 (ja) | 2002-04-30 |
| IL65447A (en) | 1987-01-30 |
| JPS6399093A (ja) | 1988-04-30 |
| CA1219824A (en) | 1987-03-31 |
| DK46797A (da) | 1997-04-28 |
| AU560651B2 (en) | 1987-04-16 |
| DE3280032D1 (en) | 1989-12-28 |
| DK171822B1 (da) | 1997-06-23 |
| JPH07107998A (ja) | 1995-04-25 |
| JP3279503B2 (ja) | 2002-04-30 |
| JPH03261798A (ja) | 1991-11-21 |
| JPH0375559B2 (de) | 1991-12-02 |
| DK160591A (da) | 1991-09-16 |
| DE3280478D1 (de) | 1998-07-16 |
| DK171382A (da) | 1982-10-18 |
| JPH1033199A (ja) | 1998-02-10 |
| JPH0880B2 (ja) | 1996-01-10 |
| IL65447A0 (en) | 1982-07-30 |
| EP0063879B1 (de) | 1989-11-23 |
| JPH0694474B2 (ja) | 1994-11-24 |
| JPH1052271A (ja) | 1998-02-24 |
| ATE167189T1 (de) | 1998-06-15 |
| DK160591D0 (da) | 1991-09-16 |
| EP0063879A2 (de) | 1982-11-03 |
| EP0063879A3 (en) | 1983-08-10 |
| DE3280478T2 (de) | 1999-02-18 |
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