DK51686A - Fremstilling af 2-alkoxy-n-(1-azabicyclo(2,2,2)octan-3-yl)-aminobenzamider - Google Patents

Fremstilling af 2-alkoxy-n-(1-azabicyclo(2,2,2)octan-3-yl)-aminobenzamider Download PDF

Info

Publication number: DK51686A
Authority: DK; Denmark
Prior art keywords: aminobenzamides; octan; azabicyclo; alkoxy; preparation
Prior art date: 1985-02-04

Application number

DK51686A

Other languages

English (en)

Other versions

DK170098B1 (da

DK51686D0 (da

Inventor

Young Sek Lo

Original Assignee

Robins Co Inc A H

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-02-04

Filing date

1986-02-03

Publication date

1986-08-05

1986-02-03 Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H

1986-02-03 Publication of DK51686D0 publication Critical patent/DK51686D0/da

1986-08-05 Publication of DK51686A publication Critical patent/DK51686A/da

1995-05-22 Application granted granted Critical

1995-05-22 Publication of DK170098B1 publication Critical patent/DK170098B1/da

Links

238000002360 preparation method Methods 0.000 title abstract 2
-1 1-AZABICYCLO (2,2,2) OCTAN-3-YL Chemical class 0.000 title 1
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
REUAXQZIRFXQML-UHFFFAOYSA-N 1-azabicyclo[2.2.2]octan-3-amine Chemical class C1CC2C(N)CN1CC2 REUAXQZIRFXQML-UHFFFAOYSA-N 0.000 abstract 1
ALYNCZNDIQEVRV-UHFFFAOYSA-N 4-aminobenzoic acid Chemical compound NC1=CC=C(C(O)=O)C=C1 ALYNCZNDIQEVRV-UHFFFAOYSA-N 0.000 abstract 1
XVMSFILGAMDHEY-UHFFFAOYSA-N 6-(4-aminophenyl)sulfonylpyridin-3-amine Chemical compound C1=CC(N)=CC=C1S(=O)(=O)C1=CC=C(N)C=N1 XVMSFILGAMDHEY-UHFFFAOYSA-N 0.000 abstract 1
241001465754 Metazoa Species 0.000 abstract 1
239000002253 acid Substances 0.000 abstract 1
229960004050 aminobenzoic acid Drugs 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000012458 free base Substances 0.000 abstract 1
230000002496 gastric effect Effects 0.000 abstract 1
125000001475 halogen functional group Chemical group 0.000 abstract 1
239000000203 mixture Substances 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
238000000746 purification Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Indole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

DK051686A 1985-02-04 1986-02-03 Fremgangsmåde til fremstilling af en blanding indeholdende pyridin, vand, et N,N'-dialkyl- eller N,N'-dicyclohexylurinstof og et 2-alkoxy-N-(1-azabicyclo(2,2,2)octan-3-yl)-aminobenzamid-syreadditionssalt, fremgangsmåde til fremstilling af et sådant aminobenzamid, fremgangsmåde til fremstilling af en pyridin/vand-opløsning af et sådant syreadditionssalt samt mellemproduktopløsning indeholdende DK170098B1 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US69794385		1985-02-04
US06/697,943 US4870181A (en)	1985-02-04	1985-02-04	Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides

Publications (3)

Publication Number	Publication Date
DK51686D0 DK51686D0 (da)	1986-02-03
DK51686A true DK51686A (da)	1986-08-05
DK170098B1 DK170098B1 (da)	1995-05-22

Family

ID=24803230

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK051686A DK170098B1 (da)	1985-02-04	1986-02-03	Fremgangsmåde til fremstilling af en blanding indeholdende pyridin, vand, et N,N'-dialkyl- eller N,N'-dicyclohexylurinstof og et 2-alkoxy-N-(1-azabicyclo(2,2,2)octan-3-yl)-aminobenzamid-syreadditionssalt, fremgangsmåde til fremstilling af et sådant aminobenzamid, fremgangsmåde til fremstilling af en pyridin/vand-opløsning af et sådant syreadditionssalt samt mellemproduktopløsning indeholdende

Country Status (21)

Country	Link
US (1)	US4870181A (da)
EP (1)	EP0190915B1 (da)
JP (1)	JPH0676407B2 (da)
KR (1)	KR930005446B1 (da)
AT (1)	ATE81856T1 (da)
AU (1)	AU589592B2 (da)
CA (1)	CA1288776C (da)
DE (1)	DE3687006T2 (da)
DK (1)	DK170098B1 (da)
FI (1)	FI84913C (da)
GR (1)	GR860320B (da)
HU (1)	HU196796B (da)
IE (1)	IE59396B1 (da)
IL (1)	IL77612A (da)
NO (1)	NO163367C (da)
NZ (1)	NZ215016A (da)
PH (1)	PH21990A (da)
PL (1)	PL148515B1 (da)
PT (1)	PT81956B (da)
YU (1)	YU45763B (da)
ZA (1)	ZA86411B (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH23937A (en) *	1986-12-16	1990-01-23	Robins Co Inc A H	Anxiolytic-n-(1-azabicyclo(2.2.2.)oct-3-yl)benzamides and thiobenzamides
FR2610323B1 (fr) *	1987-02-04	1989-06-23	Delalande Sa	Enantiomeres de configuration absolue s de derives amide de l'amino-3 quinuclidine, leur procede de preparation et leur application en therapeutique
GB8718345D0 (en) *	1987-08-03	1987-09-09	Fordonal Sa	N-substituted benzamides
EP0311724A1 (en) *	1987-10-16	1989-04-19	Synthelabo	Anxiolytic-R-N-(1-azabicyclo[2.2.2]oct-3-yl) benzamides and thiobenzamides
US4863919A (en) *	1988-02-01	1989-09-05	A. H. Robins Company, Incorporated	Method of enhancing memory or correcting memory deficiency with arylamido(and arylthiomido)-azabicycloalkanes
US4892205A (en) *	1988-07-15	1990-01-09	Hoover Universal, Inc.	Concentric ribbed preform and bottle made from same
EP0423805B1 (en)	1989-10-20	2000-08-23	Kyowa Hakko Kogyo Kabushiki Kaisha	Condensed purine derivatives
US6479510B2 (en)	2000-08-18	2002-11-12	Pharmacia & Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
AU2001282873A1 (en)	2000-08-18	2002-03-04	Pharmacia And Upjohn Company	Quinuclidine-substituted aryl compounds for treatment of disease
PE20021019A1 (es)	2001-04-19	2002-11-13	Upjohn Co	Grupos azabiciclicos sustituidos
CA2455773A1 (en) *	2001-08-24	2003-03-06	Pharmacia & Upjohn Company	Substituted-aryl 7-aza¬2.2.1\|bicycloheptanes for the treatment of disease
US6852716B2 (en)	2002-02-15	2005-02-08	Pfizer Inc	Substituted-aryl compounds for treatment of disease
EP1478646A1 (en) *	2002-02-20	2004-11-24	PHARMACIA & UPJOHN COMPANY	Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3859443A (en) *	1973-11-15	1975-01-07	Merck & Co Inc	Composition and methods of treatment employing acrylanilides as anticoccidial agents
IT1046849B (it) *	1974-06-12	1980-07-31	Snam Progetti	Processo per la preparazione di derivati adeninici macromolecola rizzati e prodotti cosi ottenuti
US4093734A (en) *	1975-11-03	1978-06-06	Boehringer Ingelheim Gmbh	Amino-benzoic acid amides
FR2529548A1 (fr) *	1982-07-02	1984-01-06	Delalande Sa	Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
JPS5936675A (ja) *	1982-07-13	1984-02-28	サンド・アクチエンゲゼルシヤフト	二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
US4593034A (en) *	1984-04-06	1986-06-03	A. H. Robins Company, Inc.	2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides

1985
- 1985-02-04 US US06/697,943 patent/US4870181A/en not_active Expired - Fee Related
1986
- 1986-01-15 IL IL77612A patent/IL77612A/xx not_active IP Right Cessation
- 1986-01-20 ZA ZA86411A patent/ZA86411B/xx unknown
- 1986-01-21 AU AU52589/86A patent/AU589592B2/en not_active Ceased
- 1986-01-24 YU YU9586A patent/YU45763B/sh unknown
- 1986-01-31 PH PH33362A patent/PH21990A/en unknown
- 1986-02-03 KR KR1019860000706A patent/KR930005446B1/ko not_active Expired - Fee Related
- 1986-02-03 CA CA000500991A patent/CA1288776C/en not_active Expired - Lifetime
- 1986-02-03 DK DK051686A patent/DK170098B1/da active
- 1986-02-03 FI FI860489A patent/FI84913C/fi not_active IP Right Cessation
- 1986-02-03 HU HU86469A patent/HU196796B/hu not_active IP Right Cessation
- 1986-02-03 IE IE28886A patent/IE59396B1/en not_active IP Right Cessation
- 1986-02-03 NO NO860373A patent/NO163367C/no unknown
- 1986-02-03 GR GR860320A patent/GR860320B/el unknown
- 1986-02-03 PL PL1986257773A patent/PL148515B1/pl unknown
- 1986-02-03 PT PT81956A patent/PT81956B/pt not_active IP Right Cessation
- 1986-02-03 NZ NZ215016A patent/NZ215016A/xx unknown
- 1986-02-04 EP EP86300728A patent/EP0190915B1/en not_active Expired - Lifetime
- 1986-02-04 JP JP61022818A patent/JPH0676407B2/ja not_active Expired - Lifetime
- 1986-02-04 DE DE8686300728T patent/DE3687006T2/de not_active Expired - Fee Related
- 1986-02-04 AT AT86300728T patent/ATE81856T1/de not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR860006463A (ko)	1986-09-11
PT81956A (en)	1986-03-01
NZ215016A (en)	1989-08-29
DK170098B1 (da)	1995-05-22
CA1288776C (en)	1991-09-10
EP0190915A2 (en)	1986-08-13
FI84913C (fi)	1992-02-10
FI860489L (fi)	1986-08-05
PL148515B1 (en)	1989-10-31
IE59396B1 (en)	1994-02-23
KR930005446B1 (ko)	1993-06-22
PT81956B (pt)	1988-01-22
JPH0676407B2 (ja)	1994-09-28
US4870181A (en)	1989-09-26
FI84913B (fi)	1991-10-31
EP0190915B1 (en)	1992-10-28
HU196796B (en)	1989-01-30
FI860489A0 (fi)	1986-02-03
NO163367C (no)	1990-05-16
YU45763B (sh)	1992-07-20
IE860288L (en)	1986-08-04
ATE81856T1 (de)	1992-11-15
YU9586A (en)	1987-12-31
IL77612A (en)	1989-09-10
AU589592B2 (en)	1989-10-19
HUT40119A (en)	1986-11-28
PH21990A (en)	1988-05-02
GR860320B (en)	1986-06-04
ZA86411B (en)	1986-09-24
EP0190915A3 (en)	1988-12-14
JPS61183286A (ja)	1986-08-15
NO163367B (no)	1990-02-05
DE3687006D1 (de)	1992-12-03
NO860373L (no)	1986-08-05
DE3687006T2 (de)	1993-04-22
AU5258986A (en)	1986-08-07
PL257773A1 (en)	1987-10-19
DK51686D0 (da)	1986-02-03

Publication	Publication Date	Title
DK51686A (da)	1986-08-05	Fremstilling af 2-alkoxy-n-(1-azabicyclo(2,2,2)octan-3-yl)-aminobenzamider
NO952869D0 (no)	1995-07-19	Aminosyrederivater, medikamenter inneholdende disse forbindelser og fremgangsmåter for fremstilling derav
DE3260543D1 (en)	1984-09-13	Processes for preparation, isolation and purification of dipeptide sweeteners
DK492989D0 (da)	1989-10-06	Aminopyrrolidinon, farmaceutisk praeparat indeholdende en saadan forbindelse og fremgangsmaade til fremstilling deraf
NO165393C (no)	1991-02-06	Fremgansmaate for fremstilling av aryloksypropanolaminer og salter av disse med difenyleddiksyre.
IT1230796B (it)	1991-10-29	Procedimento per la preparazione di acido tauroursodesossicolico biidrato.
EP0306592A3 (en)	1989-10-11	Process for concentration of an aqeous solution of amino acid
GB1470747A (en)	1977-04-21	Pyridazine derivative
FR2615510B1 (fr)	1991-09-06	Procede de preparation d'imides halogenes
SE8305362D0 (sv)	1983-09-30	Novel substituted phenylazacycloalkanes, processes for preparation and pharmaceutical preparations for such compounds
FI913161A7 (fi)	1991-06-28	Menetelmä N-(3',4'-dimetoksikinnamoyyli)antraniilihapon valmistamiseks i
ES8301230A1 (es)	1982-12-01	Un procedimiento para la preparacion de 1-fenil-5-amidotetrazoles.
ES2007387A6 (es)	1989-06-16	Procedimiento para la obtencion de un derivado del acido cromoglicico