ECSP11010980A - Compuestos heteroaromáticos espirocíclicos fusionados para el tratamiento de infecciones bacterianas - Google Patents

Compuestos heteroaromáticos espirocíclicos fusionados para el tratamiento de infecciones bacterianas

Info

Publication number
ECSP11010980A
ECSP11010980A EC2011010980A ECSP11010980A ECSP11010980A EC SP11010980 A ECSP11010980 A EC SP11010980A EC 2011010980 A EC2011010980 A EC 2011010980A EC SP11010980 A ECSP11010980 A EC SP11010980A EC SP11010980 A ECSP11010980 A EC SP11010980A
Authority
EC
Ecuador
Prior art keywords
bacterial infections
fusioned
treatment
heteroaromatic compounds
spirocyclic
Prior art date
Application number
EC2011010980A
Other languages
English (en)
Inventor
Sheila Irene Hauck
Fei Zhou
Gregory Steven Basarab
Kevin Barvian
Madhusudhan Reddy Gowravaram
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ECSP11010980A publication Critical patent/ECSP11010980A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/22—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains four or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

La presente invención se refiere a compuestos de Fórmula (I); a sales farmacéuticamente aceptables de estos, a métodos de utilización de estos para tratar infecciones bacterianas y a métodos para su preparación.
EC2011010980A 2008-10-14 2011-04-14 Compuestos heteroaromáticos espirocíclicos fusionados para el tratamiento de infecciones bacterianas ECSP11010980A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10518908P 2008-10-14 2008-10-14

Publications (1)

Publication Number Publication Date
ECSP11010980A true ECSP11010980A (es) 2011-05-31

Family

ID=41668347

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011010980A ECSP11010980A (es) 2008-10-14 2011-04-14 Compuestos heteroaromáticos espirocíclicos fusionados para el tratamiento de infecciones bacterianas

Country Status (24)

Country Link
US (1) US8658641B2 (es)
EP (1) EP2350077B1 (es)
JP (2) JP5749169B2 (es)
KR (1) KR101676886B1 (es)
CN (2) CN104086565A (es)
AR (1) AR073862A1 (es)
AU (1) AU2009305203B2 (es)
BR (1) BRPI0920180B1 (es)
CA (1) CA2736335C (es)
CL (1) CL2011000838A1 (es)
CO (1) CO6382126A2 (es)
CR (1) CR20110195A (es)
CU (1) CU20110083A7 (es)
DO (1) DOP2011000102A (es)
EA (1) EA201100613A1 (es)
EC (1) ECSP11010980A (es)
ES (1) ES2565611T3 (es)
HK (1) HK1203483A1 (es)
IL (1) IL211728A0 (es)
MX (1) MX2011003598A (es)
TW (1) TW201020258A (es)
UY (1) UY32174A (es)
WO (1) WO2010043893A1 (es)
ZA (1) ZA201103533B (es)

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EA033459B1 (ru) 2014-05-29 2019-10-31 Entasis Therapeutics Ltd Конденсированные спироциклические гетероароматические соединения для лечения бактериальных инфекций
CN106575090B (zh) * 2014-08-25 2020-02-07 日产化学工业株式会社 用于soc图案上的图案反转的被覆用组合物
US20170333435A1 (en) 2014-11-06 2017-11-23 Lysosomal Therapeutics Inc. Substituted imidazo[1,5-a]pyrimidines and their use in the treatment of medical disorders
EP4406616A3 (en) 2014-11-06 2024-11-06 Bial-R&D Investments, S.A. Substituted pyrazolo(1,5-a)pyrimidines and their use in the treatment of medical disorders
US20180185368A1 (en) 2014-11-06 2018-07-05 Lysosomal Therapeutics Inc. Substituted pyrrolo[1,2-a]pyrimidines and their use in the treatment of medical disorders
PL3292116T3 (pl) 2015-02-02 2022-02-21 Valo Health, Inc. 3-arylo-4-amidobicykliczne kwasy [4,5,0]hydroksamowe jako inhibitory hdac
TW201636329A (zh) 2015-02-02 2016-10-16 佛瑪治療公司 作為ｈｄａｃ抑制劑之雙環［４，６，０］異羥肟酸
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WO2017024455A1 (zh) * 2015-08-07 2017-02-16 苏州大学张家港工业技术研究院 一种螺环羟吲哚咪唑啉并氧氮杂卓化合物及其合成方法
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US10435478B2 (en) 2015-12-17 2019-10-08 Janssen Pharmaceutica Nv Antibodies to quetiapine and use thereof
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Also Published As

Publication number Publication date
HK1160127A1 (zh) 2012-08-10
KR20110090895A (ko) 2011-08-10
US20110245224A1 (en) 2011-10-06
EA201100613A1 (ru) 2011-12-30
AR073862A1 (es) 2010-12-09
CN102245605B (zh) 2016-01-27
BRPI0920180A2 (pt) 2020-12-29
JP5749169B2 (ja) 2015-07-15
IL211728A0 (en) 2011-06-30
CL2011000838A1 (es) 2011-10-21
CN102245605A (zh) 2011-11-16
EP2350077B1 (en) 2016-01-27
TW201020258A (en) 2010-06-01
AU2009305203B2 (en) 2013-03-07
CN104086565A (zh) 2014-10-08
US8658641B2 (en) 2014-02-25
KR101676886B1 (ko) 2016-11-16
WO2010043893A1 (en) 2010-04-22
CA2736335C (en) 2017-05-09
DOP2011000102A (es) 2011-05-15
ZA201103533B (en) 2012-01-25
BRPI0920180B1 (pt) 2021-10-26
AU2009305203A1 (en) 2010-04-22
CA2736335A1 (en) 2010-04-22
JP2015178510A (ja) 2015-10-08
CU20110083A7 (es) 2013-05-31
EP2350077A1 (en) 2011-08-03
ES2565611T3 (es) 2016-04-05
CO6382126A2 (es) 2012-02-15
MX2011003598A (es) 2011-04-27
JP2012505261A (ja) 2012-03-01
UY32174A (es) 2010-05-31
CR20110195A (es) 2011-06-08
HK1203483A1 (en) 2015-10-30

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