EG19251A - Process for preparing of azabicyclo qiunolone carboxlic acids. - Google Patents

Process for preparing of azabicyclo qiunolone carboxlic acids.

Info

Publication number: EG19251A
Authority: EG; Egypt
Prior art keywords: azabicyclo; qiunolone; preparing; alkyl; methyl
Prior art date: 1989-08-16

Application number

EG48390A

Other languages

English (en)

Inventor

Katherine Elizabeth Brighty

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-16

Filing date

1990-08-14

Publication date

1994-09-29

1990-08-14 Application filed by Pfizer filed Critical Pfizer

1994-09-29 Application granted granted Critical

1994-09-29 Publication of EG19251A publication Critical patent/EG19251A/xx

Links

239000002253 acid Substances 0.000 title 1
150000007513 acids Chemical class 0.000 title 1
238000004519 manufacturing process Methods 0.000 title 1
125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 3
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052799 carbon Inorganic materials 0.000 abstract 2
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
-1 quinolone carboxylic acids Chemical class 0.000 abstract 2
XXJGBENTLXFVFI-UHFFFAOYSA-N 1-amino-methylene Chemical compound N[CH2] XXJGBENTLXFVFI-UHFFFAOYSA-N 0.000 abstract 1
125000004777 2-fluoroethyl group Chemical group [H]C([H])(F)C([H])([H])* 0.000 abstract 1
125000001255 4-fluorophenyl group Chemical group [H]C1=C([H])C(*)=C([H])C([H])=C1F 0.000 abstract 1
125000006519 CCH3 Chemical group 0.000 abstract 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004202 aminomethyl group Chemical group [H]N([H])C([H])([H])* 0.000 abstract 1
150000001768 cations Chemical class 0.000 abstract 1
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
AQIAIZBHFAKICS-UHFFFAOYSA-N methylaminomethyl Chemical compound [CH2]NC AQIAIZBHFAKICS-UHFFFAOYSA-N 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
229940002612 prodrug Drugs 0.000 abstract 1
239000000651 prodrug Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
General Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Oncology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Indole Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Quinoline Compounds (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

EG48390A 1989-08-16 1990-08-14 Process for preparing of azabicyclo qiunolone carboxlic acids. EG19251A (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
PCT/US1989/003489 WO1991002526A1 (en)	1989-08-16	1989-08-16	Azabicyclo quinolone carboxylic acids

Publications (1)

Publication Number	Publication Date
EG19251A true EG19251A (en)	1994-09-29

Family

ID=22215165

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EG48390A EG19251A (en)	1989-08-16	1990-08-14	Process for preparing of azabicyclo qiunolone carboxlic acids.

Country Status (30)

Country	Link
EP (1)	EP0413455B1 (de)
JP (2)	JPH072734B2 (de)
KR (1)	KR930004844B1 (de)
CN (1)	CN1025192C (de)
AT (1)	ATE124040T1 (de)
AU (1)	AU623801B2 (de)
BA (1)	BA98299A (de)
CA (2)	CA2127561C (de)
CY (2)	CY1969A (de)
CZ (1)	CZ281127B6 (de)
DD (1)	DD298399A5 (de)
DE (3)	DE19875050I2 (de)
DK (1)	DK0413455T3 (de)
EG (1)	EG19251A (de)
ES (1)	ES2074131T4 (de)
FI (2)	FI108228B (de)
GR (1)	GR3017072T3 (de)
HK (1)	HK1000207A1 (de)
HU (2)	HU219403B (de)
IE (1)	IE66202B1 (de)
IL (1)	IL95331A (de)
LU (2)	LU90310I2 (de)
NL (2)	NL980032I2 (de)
NO (1)	NO300214B1 (de)
NZ (1)	NZ234920A (de)
PL (1)	PL166381B1 (de)
PT (1)	PT94998B (de)
RU (1)	RU2049777C1 (de)
WO (1)	WO1991002526A1 (de)
ZA (1)	ZA906450B (de)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0449445A3 (en) *	1990-03-27	1993-08-25	Pfizer Inc.	Preparation of beta-ketoesters useful in preparing quinolone antibiotics
FR2675144B1 (fr) *	1991-04-10	1995-06-16	Bouchara Sa	Nouvelles quinolones difluorees - leur procede de preparation et les compositions pharmaceutiques en renfermant.
CA2111463C (en) *	1991-06-19	1997-08-26	Bingwei V. Yang	Azaspiro quinolone antibacterial agents
US5256791A (en) *	1992-03-02	1993-10-26	Pfizer Inc.	Preparation of intermediates in the synthesis of quinoline antibiotics
EG20543A (en) *	1992-10-30	1999-07-31	Procter & Gamble	Process for preparing of novel antimicrobial -5- (n-heterosubstituted amino) quinolones
US5527910A (en) *	1992-12-30	1996-06-18	Cheil Foods & Chemicals, Inc.	Pyridone carboxylic acid compounds and their uses for treating infectious diseases caused by bacteria
US5591766A (en) *	1993-12-03	1997-01-07	Cheil Foods & Chemicals, Inc.	Solid oral formulations of pyridone carboxylic acids
PT812838E (pt) *	1994-02-04	2002-10-31	Dainippon Pharmaceutical Co	Derivado de acido piridonacarboxilico substituido com o grupo amino biciclico seu ester seu sal e amina biciclica como seu intermediario
PT807630E (pt) *	1995-02-02	2003-08-29	Daiichi Seiyaku Co	Compostos heterociclicos
JPH08213881A (ja) *	1995-02-02	1996-08-20	Fujitsu Ltd	周波数制御回路
WO1996024593A1 (en) *	1995-02-07	1996-08-15	Daiichi Pharmaceutical Co., Ltd.	Heterocyclic spiro derivatives
DE69503066T2 (de) *	1995-06-06	1998-10-15	Pfizer Inc., New York, N.Y.	KRISTALLFORM VON WASSERFREIEN 7-((1a,5a,6a)-6-AMINO-3-AZABICYCLO (3.1.0.) HEX-3-YL)-6-FLUORO-1-(2,4-DIFLUOROPHENYL)-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDIN-CARBONSÄURE METHANESULFONSÄURE SALZ
DE69622715T2 (de) *	1995-06-15	2002-11-14	Pfizer Inc., New York	Verfahren zur herstellung von derivaten der ein peptid enthaltenden azabizylo-naphtyridin-carbonsäure
KR100276477B1 (ko) *	1996-02-09	2000-12-15	나카노 가쓰히코	퀴놀론카복실산유도체또는그의염
AP788A (en) *	1996-08-26	1999-12-03	Pfizer	Novel crystal form of anhydrous 7-(1a, 5a, 6a)-6-Amino-3-Azabicyclo(3.1.0) hex-3-YI)-6-Fluoro-1-(2,4- Difluorophenyl)-1,4-Dihydro-4-Oxo-1, 8-Naphthyridine-3-Carboxylic Acid, Methanesulfonic acid salt.
TW519542B (en) *	1996-09-27	2003-02-01	Daiichi Seiyaku Co	Bicyclic amine derivative
ATE267191T1 (de)	1996-10-25	2004-06-15	Daiichi Seiyaku Co	Tricyclische aminderivate
US20020032216A1 (en)	1997-03-21	2002-03-14	Lg Chemical Ltd.	Salt of naphthyridine carboxylic acid derivative
MA24500A1 (fr)	1997-03-21	1998-10-01	Lg Life Sciences Ltd	Derive du sel d'acide carboxylique de naphthyridine .
DE19733439A1 (de) *	1997-08-02	1999-02-04	Bayer Ag	Neue 6-endo-Amino-3-azabicyclo(3.1.0)hexande, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung von Chinolon- und Naphthyridincarbonsäure-Derviaten mit verbesserten Eigenschaften
CN1264837C (zh)	1997-09-15	2006-07-19	普罗克特和甘保尔公司	喹诺酮抗微生物剂、其组合物和应用
US6184380B1 (en) *	1999-01-25	2001-02-06	Pfizer Inc.	Process for preparing naphthyridones and intermediates
PA8464701A1 (es) *	1998-01-16	2000-09-29	Pfizer Prod Inc	Procedimiento e intermedios para preparar naftiridonas
US7019142B2 (en)	1998-01-16	2006-03-28	Pfizer Inc.	Process for preparing naphthyridones and intermediates
GB9820405D0 (en) *	1998-09-18	1998-11-11	Smithkline Beecham Plc	Process
HK1044476B (zh)	1999-03-17	2010-09-17	第一制药株式会社	药物组合物
GB9920919D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel compound
GB9920917D0 (en)	1999-09-03	1999-11-10	Sb Pharmco Inc	Novel process
ATE304539T1 (de)	2000-12-14	2005-09-15	Procter & Gamble	Antimikrobielle chinolone
AU2002230893B2 (en)	2000-12-14	2005-06-09	The Procter & Gamble Company	Antimicrobial 2-pyridones, their compositions and uses
KR100517638B1 (ko)	2002-04-08	2005-09-28	주식회사 엘지생명과학	게미플록사신 산염의 새로운 제조방법
EA200500173A1 (ru)	2002-07-08	2005-08-25	Рэнбакси Лабораториз Лимитед	Производные 3,6-дизамещенного азабицикло[3.1.0]гексана в качестве антагонистов мускариновых рецепторов
EP1534675B1 (de)	2002-08-23	2009-02-25	Ranbaxy Laboratories, Ltd.	Fluor- und sulfonylaminohaltige, 3,6-disubstituierte azabicyclo¬3.1.0 hexanderivate als muscarinrezeptorantagonisten
EP1618091A1 (de)	2003-04-09	2006-01-25	Ranbaxy Laboratories, Ltd.	Substituierte azabicyclohexanderivate als antagonisten von muscarinrezeptoren
EP1615634B1 (de)	2003-04-10	2007-05-16	Ranbaxy Laboratories, Ltd.	Substituierte azabicyclo hexane derivate als muscarin rezeptor antagonisten
WO2004089900A1 (en)	2003-04-11	2004-10-21	Ranbaxy Laboratories Limited	Azabicyclo derivatives as muscarinic receptor antagonists
PL1666477T3 (pl)	2003-09-10	2013-11-29	Kyorin Seiyaku Kk	Pochodna kwasu 7-(4-podstawionego-3-cyklopropyloaminometylo-1- pirolidynylo)chinolonokarboksylowego
WO2005026121A1 (en) *	2003-09-18	2005-03-24	Ranbaxy Laboratories Limited	PROCESS FOR THE PREPARATION OF (1α, 5α, 6α)-6-AMINOMETHYL-3-BENZYL-3-AZABICYCLO[3.1.0]HEXANE
TWI391378B (zh) *	2006-03-16	2013-04-01	Astellas Pharma Inc	喹啉酮衍生物或其製藥學上可被容許之鹽
CA2647454A1 (en)	2006-03-28	2007-10-04	The Procter & Gamble Company	A coupling process for preparing quinolone intermediates
ES2366150T3 (es)	2006-03-28	2011-10-17	Warner Chilcott Company, Llc	Malatos de polimorfos de ácido (3s,5s)-7-[3-amino-5-metil-piperidinil]-1-ciclopropil-1,4-dihidro-8-metoxi-4-oxo-3-quinolinocarboxílico.
US7902227B2 (en) *	2007-07-27	2011-03-08	Janssen Pharmaceutica Nv.	C-7 isoxazolinyl quinolone / naphthyridine derivatives useful as antibacterial agents
BR112013007566A2 (pt)	2010-09-28	2016-08-02	Panacea Biotec Ltd	novos compostos bicíclicos
US12421210B2 (en) *	2018-10-05	2025-09-23	New York University	Fused bicyclic heterocycles as therapeutic agents
CN112442084B (zh) *	2020-12-03	2022-09-09	国药集团致君（深圳）制药有限公司	一种抗菌药中间体的制备方法
CN113307768B (zh) *	2021-04-29	2023-12-12	中国农业科学院兰州畜牧与兽药研究所	喹诺酮类衍生物及其制备方法和用途

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JPH0676400B2 (ja) *	1987-08-25	1994-09-28	大日本製薬株式会社	新規ピリドンカルボン酸誘導体、そのエステルおよびその塩
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US4973091A (en) *	1989-09-20	1990-11-27	Truth Incorporated	Sliding patio door dual point latch and lock

1989
- 1989-08-16 PL PL90286484A patent/PL166381B1/pl unknown
- 1989-08-16 HU HU9200460A patent/HU219403B/hu not_active IP Right Cessation
- 1989-08-16 RU SU5011662/04A patent/RU2049777C1/ru not_active IP Right Cessation
- 1989-08-16 WO PCT/US1989/003489 patent/WO1991002526A1/en not_active Ceased
- 1989-08-16 IE IE295090A patent/IE66202B1/en not_active IP Right Cessation
1990
- 1990-07-30 AT AT90308331T patent/ATE124040T1/de active
- 1990-07-30 ES ES90308331T patent/ES2074131T4/es not_active Expired - Lifetime
- 1990-07-30 DE DE19875050C patent/DE19875050I2/de active Active
- 1990-07-30 EP EP90308331A patent/EP0413455B1/de not_active Expired - Lifetime
- 1990-07-30 DK DK90308331.9T patent/DK0413455T3/da active
- 1990-07-30 DE DE69020262T patent/DE69020262T2/de not_active Expired - Fee Related
- 1990-07-30 DE DE19875052C patent/DE19875052I2/de active Active
- 1990-08-09 IL IL9533190A patent/IL95331A/en not_active IP Right Cessation
- 1990-08-14 KR KR1019900012528A patent/KR930004844B1/ko not_active Expired - Fee Related
- 1990-08-14 PT PT94998A patent/PT94998B/pt not_active IP Right Cessation
- 1990-08-14 EG EG48390A patent/EG19251A/xx active
- 1990-08-14 CA CA002127561A patent/CA2127561C/en not_active Expired - Lifetime
- 1990-08-14 CA CA002023217A patent/CA2023217C/en not_active Expired - Lifetime
- 1990-08-15 CN CN90106794A patent/CN1025192C/zh not_active Expired - Fee Related
- 1990-08-15 AU AU61042/90A patent/AU623801B2/en not_active Expired
- 1990-08-15 NZ NZ234920A patent/NZ234920A/en unknown
- 1990-08-15 ZA ZA906450A patent/ZA906450B/xx unknown
- 1990-08-15 DD DD90343474A patent/DD298399A5/de unknown
- 1990-08-16 JP JP2216461A patent/JPH072734B2/ja not_active Expired - Fee Related
- 1990-08-16 CZ CS904027A patent/CZ281127B6/cs not_active IP Right Cessation
1992
- 1992-02-14 NO NO920599A patent/NO300214B1/no not_active IP Right Cessation
- 1992-02-14 FI FI920632A patent/FI108228B/fi active Protection Beyond IP Right Term
1994
- 1994-07-08 JP JP6157008A patent/JPH0819099B2/ja not_active Expired - Fee Related
1995
- 1995-06-22 HU HU95P/P00380P patent/HU211681A9/hu unknown
- 1995-08-09 GR GR950402200T patent/GR3017072T3/el unknown
1996
- 1996-11-11 FI FI964520A patent/FI103879B/fi active
1997
- 1997-09-05 CY CY196997A patent/CY1969A/xx unknown
- 1997-09-12 HK HK97101767A patent/HK1000207A1/en not_active IP Right Cessation
1998
- 1998-03-30 BA BA980299A patent/BA98299A/bs unknown
- 1998-11-04 LU LU90310C patent/LU90310I2/xx unknown
- 1998-11-04 LU LU90311C patent/LU90311I2/xx unknown
- 1998-11-17 NL NL980032C patent/NL980032I2/nl unknown
- 1998-11-17 NL NL980033C patent/NL980033I2/nl unknown
1999
- 1999-05-24 CY CY1999010C patent/CY99010I2/el unknown

Also Published As

Publication number	Publication date
FI964520A0 (fi)	1996-11-11
DE19875052I2 (de)	2009-05-28
HU211681A9 (en)	1995-12-28
CY99010I2 (en)	2010-07-28
HU219403B (hu)	2001-04-28
FI920632A0 (fi)	1992-02-14
NO920599L (no)	1992-04-14
PT94998B (pt)	1997-05-28
KR910004572A (ko)	1991-03-28
NO920599D0 (no)	1992-02-14
KR930004844B1 (ko)	1993-06-09
NL980033I2 (nl)	1999-05-03
EP0413455A2 (de)	1991-02-20
LU90311I2 (fr)	1999-01-25
FI103879B1 (fi)	1999-10-15
BA98299A (bs)	2001-09-14
EP0413455A3 (en)	1991-10-09
PL286484A1 (en)	1991-05-20
DE69020262D1 (de)	1995-07-27
DE19875050I2 (de)	2009-05-28
ZA906450B (en)	1992-03-25
CA2127561C (en)	1998-07-28
FI964520L (fi)	1996-11-11
WO1991002526A1 (en)	1991-03-07
IL95331A (en)	1995-07-31
AU623801B2 (en)	1992-05-21
FI108228B (fi)	2001-12-14
PL166381B1 (pl)	1995-05-31
EP0413455B1 (de)	1995-06-21
HK1000207A1 (en)	1998-02-06
AU6104290A (en)	1991-02-21
NL980032I2 (nl)	1999-05-03
CN1025192C (zh)	1994-06-29
NZ234920A (en)	1992-06-25
JPH0386875A (ja)	1991-04-11
CN1049501A (zh)	1991-02-27
NL980033I1 (nl)	1999-02-01
IE66202B1 (en)	1995-12-13
JPH072734B2 (ja)	1995-01-18
CZ402790A3 (en)	1996-04-17
IE902950A1 (en)	1991-02-27
CZ281127B6 (cs)	1996-06-12
CA2023217A1 (en)	1991-02-17
ATE124040T1 (de)	1995-07-15
NO300214B1 (no)	1997-04-28
NL980032I1 (nl)	1999-02-01
DD298399A5 (de)	1992-02-20
ES2074131T3 (es)	1995-09-01
CA2127561A1 (en)	1991-02-17
ES2074131T4 (es)	1996-05-01
JPH07149758A (ja)	1995-06-13
LU90310I2 (fr)	1999-01-25
GR3017072T3 (en)	1995-11-30
RU2049777C1 (ru)	1995-12-10
CY1969A (en)	1997-09-05
DE69020262T2 (de)	1995-10-26
PT94998A (pt)	1991-04-18
CA2023217C (en)	1996-12-10
DK0413455T3 (da)	1995-08-14
JPH0819099B2 (ja)	1996-02-28
IL95331A0 (en)	1991-06-30
FI103879B (fi)	1999-10-15

Publication	Publication Date	Title
AU623801B2 (en)	1992-05-21	Azabicyclo quinolone carboxylic acids
JPS5452096A (en)	1979-04-24	Cephem compound, its preparation and bacteriostatic agent containing the same
FI944169A0 (fi)	1994-09-09	Menetelmä beta-fenyyli-isoseriinin ja sen analogien valmistamiseksi
HUT59919A (en)	1992-07-28	Process for producing azabicyclo-quinolon and naphtiridone derivatives and pharmaceutical compositions containing them
JPS55111463A (en)	1980-08-28	Beta-lactam compound and its preparation
AU576530B2 (en)	1988-09-01	1,3-dioxan-4-yl alkenoic acids
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