EG19361A - A process for the preparation of piperidine compound having local anaesthetica and analgetic - Google Patents

A process for the preparation of piperidine compound having local anaesthetica and analgetic

Info

Publication number
EG19361A
EG19361A EG74690A EG74690A EG19361A EG 19361 A EG19361 A EG 19361A EG 74690 A EG74690 A EG 74690A EG 74690 A EG74690 A EG 74690A EG 19361 A EG19361 A EG 19361A
Authority
EG
Egypt
Prior art keywords
anaesthetica
local
preparation
analgetic
piperidine compound
Prior art date
Application number
EG74690A
Other languages
English (en)
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Application granted granted Critical
Publication of EG19361A publication Critical patent/EG19361A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cosmetics (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
EG74690A 1989-12-21 1990-12-20 A process for the preparation of piperidine compound having local anaesthetica and analgetic EG19361A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8904298A SE8904298D0 (sv) 1989-12-21 1989-12-21 New compounds

Publications (1)

Publication Number Publication Date
EG19361A true EG19361A (en) 1994-12-30

Family

ID=20377821

Family Applications (1)

Application Number Title Priority Date Filing Date
EG74690A EG19361A (en) 1989-12-21 1990-12-20 A process for the preparation of piperidine compound having local anaesthetica and analgetic

Country Status (40)

Country Link
US (2) US5227389A (fr)
EP (1) EP0506778B1 (fr)
JP (1) JP2656152B2 (fr)
KR (1) KR0179382B1 (fr)
CN (1) CN1037841C (fr)
AT (1) ATE138650T1 (fr)
AU (1) AU647068B2 (fr)
BG (1) BG60912B1 (fr)
BR (1) BR1100379A (fr)
CA (1) CA2069608C (fr)
CZ (1) CZ278035B6 (fr)
DE (1) DE69027221T2 (fr)
DK (1) DK0506778T3 (fr)
DZ (1) DZ1468A1 (fr)
EG (1) EG19361A (fr)
ES (1) ES2087280T3 (fr)
FI (1) FI100881B (fr)
HK (1) HK22997A (fr)
HR (1) HRP920591B1 (fr)
HU (1) HU213110B (fr)
IE (1) IE74855B1 (fr)
IL (1) IL96636A (fr)
IS (1) IS1664B (fr)
LT (1) LT4005B (fr)
LV (2) LV10949B (fr)
NO (1) NO178858C (fr)
NZ (1) NZ236293A (fr)
PL (1) PL163591B1 (fr)
PT (1) PT96303B (fr)
RO (1) RO112864B1 (fr)
RU (1) RU2039043C1 (fr)
SA (1) SA91110209B1 (fr)
SE (1) SE8904298D0 (fr)
SG (1) SG46413A1 (fr)
SI (1) SI9012346B (fr)
SK (1) SK278283B6 (fr)
UA (1) UA26403A (fr)
WO (1) WO1991009845A1 (fr)
YU (1) YU48086B (fr)
ZA (1) ZA909903B (fr)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3916092B2 (ja) * 1993-09-17 2007-05-16 杏林製薬株式会社 イミダゾリジノン誘導体とその酸付加塩及び老年性痴呆症の治療薬
SE9400447D0 (sv) * 1994-02-11 1994-02-11 Astra Ab New compounds
SE9404438D0 (sv) * 1994-12-21 1994-12-21 Astra Ab New process
US5931809A (en) 1995-07-14 1999-08-03 Depotech Corporation Epidural administration of therapeutic compounds with sustained rate of release
GB9600235D0 (en) * 1996-01-05 1996-03-06 Pfizer Ltd Therapeutic agents
DE19642591A1 (de) * 1996-10-15 1998-04-16 Basf Ag Neue Piperidin-Ketocarbonsäure-Derivate, deren Herstellung und Anwendung
TW548271B (en) * 1996-12-20 2003-08-21 Astra Pharma Inc Novel piperidine derivatives having an exocyclic double bond with analgesic effects
SE9604786D0 (sv) * 1996-12-20 1996-12-20 Astra Pharma Inc New compounds
RU2125878C1 (ru) * 1996-12-26 1999-02-10 Новокузнецкий научно-исследовательский химико-фармацевтический институт Анальгетическое средство
RU2117481C1 (ru) * 1997-07-15 1998-08-20 Государственный научно-исследовательский институт органической химии и технологии Анальгетическое средство и способ его приготовления
US7799337B2 (en) 1997-07-21 2010-09-21 Levin Bruce H Method for directed intranasal administration of a composition
US20020102291A1 (en) * 1997-12-15 2002-08-01 Noven Pharmaceuticals, Inc. Compositions and method for treatment of attention deficit disorder and attention deficit/hyperactivity disorder with methylphenidate
SE9803240D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab A pharmaceutical composition having a rapid action
SE9803239D0 (sv) * 1998-09-24 1998-09-24 Diabact Ab Composition for the treatment of acute pain
CA2443672C (fr) * 2001-04-12 2011-03-29 Pharmacopeia, Inc. Aryl et biaryl piperidines utilisees en tant qu'antagonistes de la mch
RU2203041C1 (ru) * 2001-12-27 2003-04-27 Закрытое акционерное общество "Брынцалов-А" Спазмолитические таблетки бралангин
ATE496028T1 (de) * 2002-02-08 2011-02-15 Ono Pharmaceutical Co Piperidinderivatverbindungen und arzneimittel, die diese verbindungen als wirkstoff enthalten
CN1744899A (zh) * 2002-12-13 2006-03-08 史密丝克莱恩比彻姆公司 作为ccr5拮抗剂的哌啶衍生物
US20100210633A1 (en) * 2006-10-12 2010-08-19 Epix Delaware, Inc. Carboxamide compounds and their use
AU2008335135A1 (en) 2007-12-11 2009-06-18 Cytopathfinder, Inc. Carboxamide compounds and their use as chemokine receptor agonists
US8473062B2 (en) 2008-05-01 2013-06-25 Autonomic Technologies, Inc. Method and device for the treatment of headache
US8412336B2 (en) 2008-12-29 2013-04-02 Autonomic Technologies, Inc. Integrated delivery and visualization tool for a neuromodulation system
US9320908B2 (en) 2009-01-15 2016-04-26 Autonomic Technologies, Inc. Approval per use implanted neurostimulator
US8494641B2 (en) 2009-04-22 2013-07-23 Autonomic Technologies, Inc. Implantable neurostimulator with integral hermetic electronic enclosure, circuit substrate, monolithic feed-through, lead assembly and anchoring mechanism
EP3914246A1 (fr) 2019-01-22 2021-12-01 ICM (Institut du Cerveau et de la Moelle Épinière) Anesthésique local pour le traitement de symptômes neurologiques résultant de dysfonctionnements cérébraux

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE96980C1 (fr)
US2486796A (en) * 1943-06-25 1949-11-01 Ciba Pharm Prod Inc Esters of 1-alkyl-4-hydroxyphenylpiperidyl-4-ketones
US3334106A (en) * 1964-10-20 1967-08-01 Aldrich Chem Co Inc N(aryl)n(hydrocarbyl)-omega-(4-phenyl-4-piperidinocarbonylheteroamine) alkanoamide
US3539580A (en) * 1967-06-26 1970-11-10 Janssen Pharm 4-aryl-4-aminoalkoxy-piperidines
CH498836A (de) * 1968-12-20 1970-11-15 Geigy Ag J R Verfahren zur Herstellung von neuen Piperidinderivaten
US3737538A (en) * 1968-12-30 1973-06-05 Ciba Geigy Corp Antitussive compositions and method with isonipecotic acid derivatives
FR2156470A2 (en) * 1971-10-21 1973-06-01 Synthelabo 1-(3,3-diphenyl-1-propyl)-4-aryl-piperidines - as analgesics spasmolytic and anti-tussive agents
ZA899436B (en) * 1988-12-12 1990-08-29 Ciba Geigy Piperidine derivatives
US5100903A (en) * 1989-05-12 1992-03-31 Anaquest, Inc. N-aryl-n-(1-substituted-3-alkoxy-4-piperidinyl)amides and pharmaceutical compositions and methods employing such compounds

Also Published As

Publication number Publication date
DK0506778T3 (da) 1996-10-07
EP0506778B1 (fr) 1996-05-29
HU9202044D0 (en) 1992-09-28
LV10949A (lv) 1995-12-20
SK658190A3 (en) 1996-08-07
PT96303A (pt) 1991-09-30
HU213110B (en) 1997-02-28
SK278283B6 (en) 1996-08-07
LTIP1731A (en) 1995-07-25
KR927003531A (ko) 1992-12-18
FI922806L (fi) 1992-06-17
JPH05502869A (ja) 1993-05-20
SA91110209B1 (ar) 2004-05-08
IE74855B1 (en) 1997-08-13
LT4005B (en) 1996-07-25
IL96636A (en) 1994-11-28
NO922380D0 (no) 1992-06-17
YU234690A (sh) 1993-10-20
CZ278035B6 (en) 1993-07-14
CZ658190A3 (en) 1993-01-13
DE69027221T2 (de) 1996-10-10
UA26403A (uk) 1999-08-30
LV5766B4 (lv) 1997-06-20
YU48086B (sh) 1997-01-08
RU2039043C1 (ru) 1995-07-09
SI9012346A (sl) 1998-08-31
FI922806A0 (fi) 1992-06-17
HRP920591A2 (en) 1997-08-31
SI9012346B (sl) 1999-08-31
BG96513A (bg) 1993-12-24
AU647068B2 (en) 1994-03-17
ATE138650T1 (de) 1996-06-15
NZ236293A (en) 1992-10-28
BR1100379A (pt) 1999-12-07
WO1991009845A1 (fr) 1991-07-11
HRP920591B1 (en) 1998-12-31
BG60912B1 (bg) 1996-06-28
JP2656152B2 (ja) 1997-09-24
DZ1468A1 (fr) 2004-09-13
IS1664B (is) 1997-07-04
IL96636A0 (en) 1991-09-16
CA2069608C (fr) 2001-07-10
PL288409A1 (en) 1991-12-02
SG46413A1 (en) 1998-02-20
CN1053605A (zh) 1991-08-07
HK22997A (en) 1997-02-27
US5227389A (en) 1993-07-13
LV5766A4 (lv) 1996-12-20
CN1037841C (zh) 1998-03-25
CA2069608A1 (fr) 1991-06-22
PL163591B1 (pl) 1994-04-29
ES2087280T3 (es) 1996-07-16
PT96303B (pt) 1998-07-31
NO178858C (no) 1996-06-19
LV10949B (en) 1996-06-20
EP0506778A1 (fr) 1992-10-07
NO922380L (no) 1992-06-17
NO178858B (no) 1996-03-11
SE8904298D0 (sv) 1989-12-21
RO112864B1 (ro) 1998-01-30
FI100881B (fi) 1998-03-13
DE69027221D1 (de) 1996-07-04
IE904534A1 (en) 1991-07-03
IS3659A7 (is) 1991-06-22
KR0179382B1 (ko) 1999-03-20
AU6978391A (en) 1991-07-24
HUT64518A (en) 1994-01-28
US5360805A (en) 1994-11-01
ZA909903B (en) 1991-08-28

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