ES2020357A6 - Metodo para solubilizar yno estabilizar polipetidos, especialmente proteinas. - Google Patents

Metodo para solubilizar yno estabilizar polipetidos, especialmente proteinas.

Info

Publication number
ES2020357A6
ES2020357A6 ES8903338A ES8903338A ES2020357A6 ES 2020357 A6 ES2020357 A6 ES 2020357A6 ES 8903338 A ES8903338 A ES 8903338A ES 8903338 A ES8903338 A ES 8903338A ES 2020357 A6 ES2020357 A6 ES 2020357A6
Authority
ES
Spain
Prior art keywords
cyclodextrin
peptide complexes
maltosyl
glucosyl
solubilization
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
ES8903338A
Other languages
English (en)
Inventor
Maninder S Hora
Warren Stern
Joseph Rubinfeld
Gregory J Wong
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cetus Oncology Corp
Original Assignee
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26943506&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2020357(A6) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cetus Corp filed Critical Cetus Corp
Publication of ES2020357A6 publication Critical patent/ES2020357A6/es
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nanotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

UN METODO PARA SOLUBILIZAR Y/O ESTABILIZAR POLIPEPTIDOS, ESPECIALMENTE PROTEINAS, QUE COMPRENDE COMBINAR EL POLIPEPTIDO CON UNA CICLODEXTRINA SELECCIONADA DEL GRUPO QUE CONSISTE EN DERIVADOS DE HIDROXIPROPILO, HIDROXIETILO, GLUCOSILO, MALTOSILO Y MALTOTRIOSILO DE CICLODEXTRINA, EN UNA RELACION EN PESO DE CICLODEXTRINA A POLIPEPTIDO DE APROXIMADAMENTE 1:1 A APROXIMADAMENTE 200:1.
ES8903338A 1988-10-05 1989-10-04 Metodo para solubilizar yno estabilizar polipetidos, especialmente proteinas. Expired - Fee Related ES2020357A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25372088A 1988-10-05 1988-10-05
US07/373,928 US5997856A (en) 1988-10-05 1989-06-29 Method and compositions for solubilization and stabilization of polypeptides, especially proteins

Publications (1)

Publication Number Publication Date
ES2020357A6 true ES2020357A6 (es) 1991-08-01

Family

ID=26943506

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8903338A Expired - Fee Related ES2020357A6 (es) 1988-10-05 1989-10-04 Metodo para solubilizar yno estabilizar polipetidos, especialmente proteinas.

Country Status (9)

Country Link
US (2) US5997856A (es)
EP (1) EP0437478B1 (es)
JP (1) JP3120987B2 (es)
AU (1) AU620926B2 (es)
CA (1) CA1328634C (es)
DK (1) DK175923B1 (es)
ES (1) ES2020357A6 (es)
IE (1) IE63649B1 (es)
WO (1) WO1990003784A1 (es)

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US5730969A (en) 1998-03-24
AU620926B2 (en) 1992-02-27
IE893201L (en) 1990-04-05
DK60691D0 (da) 1991-04-05
EP0437478B1 (en) 1993-04-14
JP3120987B2 (ja) 2000-12-25
DK60691A (da) 1991-06-04
AU4338289A (en) 1990-05-01
DK175923B1 (da) 2005-07-04
US5997856A (en) 1999-12-07
JPH11500404A (ja) 1999-01-12
CA1328634C (en) 1994-04-19
EP0437478A1 (en) 1991-07-24
WO1990003784A1 (en) 1990-04-19
IE63649B1 (en) 1995-05-31

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