ES2128668T3 - Agonistas del receptor de 5-ht4. - Google Patents

Agonistas del receptor de 5-ht4.

Info

Publication number
ES2128668T3
ES2128668T3 ES95307480T ES95307480T ES2128668T3 ES 2128668 T3 ES2128668 T3 ES 2128668T3 ES 95307480 T ES95307480 T ES 95307480T ES 95307480 T ES95307480 T ES 95307480T ES 2128668 T3 ES2128668 T3 ES 2128668T3
Authority
ES
Spain
Prior art keywords
sub
group
receptor agonists
renting
alkylmetile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95307480T
Other languages
English (en)
Inventor
Haruhiko Kikuchi
Hiroaki Satoh
Masashi Suzuki
Ruta Fukutomi
Masahiro Ueno
Koichiro Hagihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Application granted granted Critical
Publication of ES2128668T3 publication Critical patent/ES2128668T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

COMPUESTOS DE FORMULA (I) Y SALES FARMACEUTICAMENTE ACEPTABLES DE ESTOS SON AGONISTAS SELECTIVOS PARA RECEPTORES 5-HT{SUB,4} DONDE AK ES UN GRUPO ALQUILO C{SUB,3-6} Y R ES UN GRUPO ALQUIL C{SUB,3-6}, UN GRUPO ALKENILO C{SUB,3-6}, UN GRUPO ALKINILO C{SUB,3-6}, UN GRUPO CICLOALQUILO C{SUB,3-7} O UN GRUPO CICLOALQUILMETILO C{SUB,3-6}.
ES95307480T 1994-10-20 1995-10-20 Agonistas del receptor de 5-ht4. Expired - Lifetime ES2128668T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25490794 1994-10-20

Publications (1)

Publication Number Publication Date
ES2128668T3 true ES2128668T3 (es) 1999-05-16

Family

ID=17271511

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95307480T Expired - Lifetime ES2128668T3 (es) 1994-10-20 1995-10-20 Agonistas del receptor de 5-ht4.

Country Status (8)

Country Link
US (1) US5684003A (es)
EP (1) EP0708105B1 (es)
KR (1) KR960014128A (es)
CA (1) CA2160420A1 (es)
DE (1) DE69506826T2 (es)
DK (1) DK0708105T3 (es)
ES (1) ES2128668T3 (es)
TW (1) TW403747B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0829474B1 (en) * 1995-05-31 2003-04-09 Nisshin Seifun Group Inc. Indazole derivatives having monocyclic amino group
US6069152A (en) * 1997-10-07 2000-05-30 Eli Lilly And Company 5-HT4 agonists and antagonists
US5914405A (en) * 1997-10-07 1999-06-22 Eli Lilly And Company Process for preparing 3-substituted indazoles
FR2792318B1 (fr) * 1999-04-16 2001-06-15 Synthelabo Derives d'indazole, leur preparation et leur application en therapeutique
US7671097B2 (en) * 2005-05-24 2010-03-02 Georgia-Pacific Chemicals Llc Stable phenolic resin polymer dispersions having low free aldehyde content
CN1589269A (zh) 2001-10-26 2005-03-02 康涅狄格大学 杂1,2－二氢化茚:一类新型有效的大麻配体
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
DE602005014566D1 (de) * 2004-11-05 2009-07-02 Theravance Inc Chinolinon-carboxamid-verbindungen
DE602005016446D1 (de) * 2004-11-05 2009-10-15 Theravance Inc 5-HT4-Rezeptoragonistenverbindungen
CA2588037A1 (en) * 2004-12-22 2006-06-29 Theravance, Inc. Indazole-carboxamide compounds
US7446114B2 (en) * 2005-03-02 2008-11-04 Theravance, Inc. Quinolinone compounds as 5-HT4 receptor agonists
JOP20130213B1 (ar) * 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
MA40771B1 (fr) 2014-09-29 2021-09-30 Takeda Pharmaceuticals Co Forme cristalline de 1-(1-méthyl-1h-pyrazol -4-yl)-n- ((1r,5s,7s) -9-méthyl-3-oxa-9-azabicyclo[3.3.1]nonan-7-yl)-1h-indole-3-carboxamide
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
TW202412782A (zh) * 2022-05-25 2024-04-01 天主教魯汶大學 用於治療ｔｒｐｍ３介導之病症的吲唑衍生物

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8829079D0 (en) * 1988-12-13 1989-01-25 Beecham Group Plc Novel compounds
GB9009389D0 (en) * 1990-04-26 1990-06-20 Smith Kline French Lab Treatment
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
US5256656A (en) * 1990-07-31 1993-10-26 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives
TW251287B (es) * 1993-04-30 1995-07-11 Nissei Co Ltd

Also Published As

Publication number Publication date
TW403747B (en) 2000-09-01
EP0708105A1 (en) 1996-04-24
EP0708105B1 (en) 1998-12-23
CA2160420A1 (en) 1996-04-21
DE69506826D1 (de) 1999-02-04
US5684003A (en) 1997-11-04
DE69506826T2 (de) 1999-08-05
DK0708105T3 (da) 1999-08-23
KR960014128A (ko) 1996-05-22

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