ES2128668T3 - Agonistas del receptor de 5-ht4. - Google Patents

Agonistas del receptor de 5-ht4.

Info

Publication number
ES2128668T3
ES2128668T3 ES95307480T ES95307480T ES2128668T3 ES 2128668 T3 ES2128668 T3 ES 2128668T3 ES 95307480 T ES95307480 T ES 95307480T ES 95307480 T ES95307480 T ES 95307480T ES 2128668 T3 ES2128668 T3 ES 2128668T3
Authority
ES
Spain
Prior art keywords
sub
group
receptor agonists
renting
alkylmetile
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95307480T
Other languages
English (en)
Inventor
Haruhiko Kikuchi
Hiroaki Satoh
Masashi Suzuki
Ruta Fukutomi
Masahiro Ueno
Koichiro Hagihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nisshin Seifun Group Inc
Original Assignee
Nisshin Seifun Group Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nisshin Seifun Group Inc filed Critical Nisshin Seifun Group Inc
Application granted granted Critical
Publication of ES2128668T3 publication Critical patent/ES2128668T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

COMPUESTOS DE FORMULA (I) Y SALES FARMACEUTICAMENTE ACEPTABLES DE ESTOS SON AGONISTAS SELECTIVOS PARA RECEPTORES 5-HT{SUB,4} DONDE AK ES UN GRUPO ALQUILO C{SUB,3-6} Y R ES UN GRUPO ALQUIL C{SUB,3-6}, UN GRUPO ALKENILO C{SUB,3-6}, UN GRUPO ALKINILO C{SUB,3-6}, UN GRUPO CICLOALQUILO C{SUB,3-7} O UN GRUPO CICLOALQUILMETILO C{SUB,3-6}.
ES95307480T 1994-10-20 1995-10-20 Agonistas del receptor de 5-ht4. Expired - Lifetime ES2128668T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP25490794 1994-10-20

Publications (1)

Publication Number Publication Date
ES2128668T3 true ES2128668T3 (es) 1999-05-16

Family

ID=17271511

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95307480T Expired - Lifetime ES2128668T3 (es) 1994-10-20 1995-10-20 Agonistas del receptor de 5-ht4.

Country Status (8)

Country Link
US (1) US5684003A (es)
EP (1) EP0708105B1 (es)
KR (1) KR960014128A (es)
CA (1) CA2160420A1 (es)
DE (1) DE69506826T2 (es)
DK (1) DK0708105T3 (es)
ES (1) ES2128668T3 (es)
TW (1) TW403747B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996038420A1 (en) * 1995-05-31 1996-12-05 Nisshin Flour Milling Co., Ltd. Indazole derivatives having monocyclic amino group
US5914405A (en) * 1997-10-07 1999-06-22 Eli Lilly And Company Process for preparing 3-substituted indazoles
US6069152A (en) * 1997-10-07 2000-05-30 Eli Lilly And Company 5-HT4 agonists and antagonists
FR2792318B1 (fr) * 1999-04-16 2001-06-15 Synthelabo Derives d'indazole, leur preparation et leur application en therapeutique
US7671097B2 (en) * 2005-05-24 2010-03-02 Georgia-Pacific Chemicals Llc Stable phenolic resin polymer dispersions having low free aldehyde content
WO2003035005A2 (en) 2001-10-26 2003-05-01 University Of Connecticut Heteroindanes: a new class of potent cannabimimetic ligands
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
DE602005014566D1 (de) * 2004-11-05 2009-07-02 Theravance Inc Chinolinon-carboxamid-verbindungen
DE602005016446D1 (de) * 2004-11-05 2009-10-15 Theravance Inc 5-HT4-Rezeptoragonistenverbindungen
ATE469897T1 (de) * 2004-12-22 2010-06-15 Theravance Inc Indazolcarbonsäureamidverbindungen
BRPI0608392A2 (pt) * 2005-03-02 2009-12-29 Theravance Inc compostos de quinolinona como agonistas do receptor 5-ht4
JOP20130213B1 (ar) * 2012-07-17 2021-08-17 Takeda Pharmaceuticals Co معارضات لمستقبلht3-5
JP7055017B2 (ja) 2014-09-29 2022-04-15 武田薬品工業株式会社 結晶形の１－（１－メチル－１ｈ－ピラゾール－４－イル）－ｎ－（（１ｒ，５ｓ，７ｓ）－９－メチル－３－オキサ－９－アザビシクロ［３．３．１］ノナン－７－イル）－１ｈ－インドール－３－カルボキサミド
GB201511382D0 (en) 2015-06-29 2015-08-12 Imp Innovations Ltd Novel compounds and their use in therapy
TW202412782A (zh) * 2022-05-25 2024-04-01 天主教魯汶大學 用於治療ｔｒｐｍ３介導之病症的吲唑衍生物
CN119997982A (zh) 2022-09-09 2025-05-13 迈里克斯制药有限公司 包含nmt抑制剂的抗体药物偶联物及其用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8829079D0 (en) * 1988-12-13 1989-01-25 Beecham Group Plc Novel compounds
GB9009389D0 (en) * 1990-04-26 1990-06-20 Smith Kline French Lab Treatment
US5187166A (en) * 1990-07-31 1993-02-16 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives and their use as antiemetics
US5256656A (en) * 1990-07-31 1993-10-26 Nisshin Flour Milling Co., Ltd. Azabicyclo derivatives
TW251287B (es) * 1993-04-30 1995-07-11 Nissei Co Ltd

Also Published As

Publication number Publication date
DK0708105T3 (da) 1999-08-23
US5684003A (en) 1997-11-04
DE69506826D1 (de) 1999-02-04
DE69506826T2 (de) 1999-08-05
KR960014128A (ko) 1996-05-22
TW403747B (en) 2000-09-01
CA2160420A1 (en) 1996-04-21
EP0708105B1 (en) 1998-12-23
EP0708105A1 (en) 1996-04-24

Similar Documents

Publication Publication Date Title
ES2132580T3 (es) Derivados de aroil-piperidina.
ES2031513T3 (es) Quinazolindionas y piridopirimidinadionas.
DK0776893T3 (da) Azaheterocykliske forbindelser med tachykininreceptorantagonistaktivitet; NK1 og NK2
EA199700156A1 (ru) Производные индола как антагонисты рецептора 5-нт
ES2029812T3 (es) Un procedimiento para preparar alfa-alquil-4-amino-3-quinolina-metanoles y 1-(4-aralquilamino-3-quinolil)alcanonas.
ATE35506T1 (de) Selektive methode zum blockieren von 5ht2 rezeptoren.
ES538418A0 (es) Un derivado de indol-3-carboxamida
ES2091963T3 (es) Indoles 3-piperidinilmetilcarboxilato sustituidos.
ES2127789T3 (es) Derivados de 1,2,4-triazol 4-sustituidos.
TR200000025T2 (tr) Azetidinilpropilpiperidin türevleri, ara bağlarıyla tacikinin antagonistleri olarak kullanımları.
GB8904551D0 (en) Chemical compounds
SE8505715D0 (sv) Indolderivat
ES2164881T3 (es) Derivados de 6-carboxamido dihidropirano.
EA199700242A1 (ru) Индазолкарбоксамиды, способ их получения, фармкомпозиция и способ ингибирования 5-нтрецептора
AU547319B2 (en) 1-(3-halo-2-pyridinyl) piperazine
DK0708105T3 (da) 5-HT4-receptoragonister
ATE253045T1 (de) Phenylsulfonamid-phenylethylamine nützlich als dopamin-rezeptoren
ES2133767T3 (es) N-(2-(pirrolidinil-1)-1-feniletil)acetamidas como agonistas de receptores kappa.
PT1204658E (pt) Agonistas benzofurilpiperazina de serotonina
MX9700080A (es) Derivados de aril y heteroaril alcoxinaftaleno.
EA200100182A1 (ru) Лечение состояний тревожности
PT96422A (pt) Processo para a preparacao de derivados de piperidina e de pirrolidina uteis como agentes anticolinergicos
FI943872A0 (fi) 2,6-metano-2H-kinditsiinijohdannainen 5-HT3-reseptoriantagonistina
ES2042395B1 (es) Procedimiento para la obtencion de derivados de 2-ciano-3-piperacinilquinoxalinas.
ATE243695T1 (de) 5-bicycloindolverbindungen

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 708105

Country of ref document: ES