ID29777A - S-nitrosotiol sebagai zat-zat untuk pengobatan gangguan fungsi peredaran darah - Google Patents

S-nitrosotiol sebagai zat-zat untuk pengobatan gangguan fungsi peredaran darah

Info

Publication number
ID29777A
ID29777A IDW00200101662A ID20011662A ID29777A ID 29777 A ID29777 A ID 29777A ID W00200101662 A IDW00200101662 A ID W00200101662A ID 20011662 A ID20011662 A ID 20011662A ID 29777 A ID29777 A ID 29777A
Authority
ID
Indonesia
Prior art keywords
nitrosotiol
substance
treatment
blood circulation
circulation function
Prior art date
Application number
IDW00200101662A
Other languages
English (en)
Indonesian (id)
Inventor
Repolles Moliner Jose
Salas Perez Rasilla Eduardo
Pubill Coy Francisco
Cerda Riudavets Juan Antonio
Negrie Rofes Cristina
Cabeza Llorente Lydia
Ferrer Siso Alicia
Trias Adroher Nuria
Cardo Banus Marcel Li
Murat Moreno Jesus
Michelena Llaguno Pedro
Original Assignee
Lacer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lacer Sa filed Critical Lacer Sa
Publication of ID29777A publication Critical patent/ID29777A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C381/00—Compounds containing carbon and sulfur and having functional groups not covered by groups C07C301/00 - C07C337/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/54—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/56—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
IDW00200101662A 1999-01-27 2000-01-19 S-nitrosotiol sebagai zat-zat untuk pengobatan gangguan fungsi peredaran darah ID29777A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES009900159A ES2147162B1 (es) 1999-01-27 1999-01-27 "s-nitrosotioles como agentes para el tratamiento de disfunciones circulatorias".

Publications (1)

Publication Number Publication Date
ID29777A true ID29777A (id) 2001-10-11

Family

ID=8307080

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW00200101662A ID29777A (id) 1999-01-27 2000-01-19 S-nitrosotiol sebagai zat-zat untuk pengobatan gangguan fungsi peredaran darah

Country Status (37)

Country Link
US (1) US6800612B2 (is)
EP (1) EP1157987B1 (is)
JP (1) JP3795330B2 (is)
KR (1) KR100671878B1 (is)
CN (1) CN1166631C (is)
AP (1) AP1439A (is)
AT (1) ATE249428T1 (is)
AU (1) AU764725B2 (is)
BG (1) BG64983B1 (is)
BR (1) BR0007395B1 (is)
CA (1) CA2359027C (is)
CU (1) CU23098A3 (is)
CZ (1) CZ298871B6 (is)
DE (2) DE60005154T2 (is)
DK (1) DK1157987T3 (is)
EA (1) EA003577B1 (is)
EE (1) EE04524B1 (is)
ES (2) ES2147162B1 (is)
GB (1) GB2363604B (is)
GE (1) GEP20043220B (is)
HK (1) HK1043586A1 (is)
HR (1) HRP20010562B1 (is)
HU (1) HUP0105203A3 (is)
ID (1) ID29777A (is)
IL (1) IL144381A (is)
IS (1) IS2153B (is)
MX (1) MXPA01007570A (is)
NO (1) NO326806B1 (is)
NZ (1) NZ513162A (is)
OA (1) OA11823A (is)
PL (1) PL202372B1 (is)
PT (1) PT1157987E (is)
RS (1) RS50072B (is)
SI (1) SI1157987T1 (is)
TR (1) TR200102003T2 (is)
WO (1) WO2000044714A1 (is)
ZA (1) ZA200106182B (is)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2173044B1 (es) * 2001-03-13 2004-01-16 Lacer Sa Derivados de glicina, n-(n-l-gamma-glutamil-3-(nitrosotio)-l-valil) y sus aplicaciones.
EP1673384A4 (en) * 2003-09-26 2007-02-07 Nitromed Inc NITROSED GLUTAMINE ACID COMPOUNDS, COMPOSITIONS AND USE METHOD
EP1939179A1 (en) * 2006-12-28 2008-07-02 Lacer, S.A. Stable S-nitrosothiols, method of synthesis and use
WO2009050527A1 (en) 2007-10-17 2009-04-23 Biotech Hungary Kutató És Fejlesztési Kft. Pharmaceutical composition comprising s-nitrosoglutathione and polysaccharide

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US37839A (en) * 1863-03-03 Improved spoke-machine
GB1567561A (en) 1977-01-18 1980-05-14 Ucb Sa Amino-spiro(oxa-(orthia)cycloalkane-penam) - carboxylic acids
GB2052497B (en) 1979-06-25 1983-06-29 Ucb Sa 6 - amino - spiro - (penam - 2,4' - piperidine) - 3 - carboxylic acid derivatives
DE3805965A1 (de) 1988-02-25 1989-09-07 Tamas Geb Szenasi Eszter Verwendung der pflanze euphorbia hirta l. und ihrer extrakte sowie ihrer wirkstoffe
US5025001A (en) 1988-06-15 1991-06-18 Brigham And Women's Hospital S-nitroso derivatives of ACE inhibitors and the use thereof
DE69008454T2 (de) * 1989-08-07 1994-08-25 Takeda Chemical Industries Ltd Nitrolsothiolderivate, ihre Herstellung und Verwendung.
ES2095317T3 (es) 1990-04-26 1997-02-16 Senju Pharma Co Inhibidor de enfermedades hepaticas.
US5187305A (en) * 1990-11-26 1993-02-16 Glaxo Inc. S-nitroso-N-alkonoylpenicillamines
AU3071592A (en) 1991-11-14 1993-06-15 Brigham And Women's Hospital Nitrosylation of protein sh groups and amino acid residues as a therapeutic modality
IL106600A (en) 1992-08-07 1997-09-30 Sankyo Co Peptides, pharmaceutical compositions containing the same and processes for the preparation thereof
DE69433478T2 (de) * 1993-09-17 2004-11-25 Brigham And Women's Hospital, Boston Verwendung von stickoxid-addukten zur verhütung von thrombosen auf artifiziellen und vaskulären oberflächen
US5728705A (en) 1993-10-04 1998-03-17 The Trustees Of Columbia University In The City Of New York Method of inducing vasorelaxation to treat pulmonary hypertension
ATE192922T1 (de) 1993-11-02 2000-06-15 Us Health Verwendung von stickstoffoxid freisetzenden verbindungen zur herstellung eines arzneimittels zum schutz gegen die ischämischen reperfusionsschäden
GB9423868D0 (en) 1994-11-25 1995-01-11 Wellcome Found Compounds for use in medicine
US6627738B2 (en) 1995-09-15 2003-09-30 Duke University No-modified hemoglobins and uses therefor
AU6782198A (en) 1997-03-27 1998-10-20 Trustees Of Boston University Novel antiplatelet agent

Also Published As

Publication number Publication date
GB2363604B (en) 2003-09-10
IL144381A (en) 2005-08-31
DE10083902T1 (de) 2002-01-10
CZ298871B6 (cs) 2008-02-27
BG105824A (en) 2002-06-28
CU23098A3 (es) 2005-11-18
BG64983B1 (bg) 2006-11-30
NZ513162A (en) 2003-01-31
ES2206178T3 (es) 2004-05-16
KR20010101767A (ko) 2001-11-14
NO20013385D0 (no) 2001-07-06
YU53601A (sh) 2004-03-12
CN1337946A (zh) 2002-02-27
NO326806B1 (no) 2009-02-16
CZ20012678A3 (cs) 2001-10-17
AU764725B2 (en) 2003-08-28
DK1157987T3 (da) 2003-11-24
JP2002535385A (ja) 2002-10-22
GB0120581D0 (en) 2001-10-17
BR0007395B1 (pt) 2010-11-16
SI1157987T1 (en) 2004-02-29
EA200100823A1 (ru) 2002-02-28
EP1157987B1 (en) 2003-09-10
HRP20010562B1 (en) 2010-08-31
ES2147162B1 (es) 2001-03-16
ZA200106182B (en) 2002-10-28
HUP0105203A3 (en) 2002-08-28
KR100671878B1 (ko) 2007-01-19
AP1439A (en) 2005-06-27
AU3046000A (en) 2000-08-18
HRP20010562A2 (en) 2002-08-31
CN1166631C (zh) 2004-09-15
GEP20043220B (en) 2004-04-26
ES2147162A1 (es) 2000-08-16
US6800612B2 (en) 2004-10-05
GB2363604A (en) 2002-01-02
PL202372B1 (pl) 2009-06-30
EE200100389A (et) 2002-12-16
EP1157987A1 (en) 2001-11-28
IS6020A (is) 2001-07-23
WO2000044714A1 (es) 2000-08-03
CA2359027C (en) 2008-10-28
PT1157987E (pt) 2004-01-30
AP2001002247A0 (en) 2001-09-30
HUP0105203A2 (en) 2002-06-29
US20020058629A1 (en) 2002-05-16
CA2359027A1 (en) 2000-08-03
PL349006A1 (en) 2002-06-17
IS2153B (is) 2006-10-13
HK1043586A1 (en) 2002-09-20
OA11823A (en) 2005-08-16
DE60005154T2 (de) 2004-07-08
JP3795330B2 (ja) 2006-07-12
MXPA01007570A (es) 2003-05-14
EA003577B1 (ru) 2003-06-26
IL144381A0 (en) 2002-05-23
RS50072B (sr) 2009-01-22
EE04524B1 (et) 2005-08-15
NO20013385L (no) 2001-09-17
BR0007395A (pt) 2001-10-30
ATE249428T1 (de) 2003-09-15
DE60005154D1 (de) 2003-10-16
TR200102003T2 (tr) 2001-12-21

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