IES20180250A2 - Butyraldehyde oxime drug itermediates synthesis method - Google Patents
Butyraldehyde oxime drug itermediates synthesis methodInfo
- Publication number
- IES20180250A2 IES20180250A2 IES20180250A IES20180250A2 IE S20180250 A2 IES20180250 A2 IE S20180250A2 IE S20180250 A IES20180250 A IE S20180250A IE S20180250 A2 IES20180250 A2 IE S20180250A2
- Authority
- IE
- Ireland
- Prior art keywords
- solution
- added
- synthesis method
- butyraldehyde oxime
- itermediates
- Prior art date
Links
- DMJZWFZICOEEAJ-UHFFFAOYSA-N 2-(4-bromothiophen-3-yl)sulfanylpropanoic acid Chemical compound OC(=O)C(C)SC1=CSC=C1Br DMJZWFZICOEEAJ-UHFFFAOYSA-N 0.000 title abstract 3
- 239000003814 drug Substances 0.000 title abstract 3
- 229940079593 drug Drugs 0.000 title abstract 3
- 238000001308 synthesis method Methods 0.000 title abstract 2
- 239000000243 solution Substances 0.000 abstract 7
- FJKIXWOMBXYWOQ-UHFFFAOYSA-N ethenoxyethane Chemical compound CCOC=C FJKIXWOMBXYWOQ-UHFFFAOYSA-N 0.000 abstract 2
- 239000000543 intermediate Substances 0.000 abstract 2
- IOLCXVTUBQKXJR-UHFFFAOYSA-M potassium bromide Chemical compound [K+].[Br-] IOLCXVTUBQKXJR-UHFFFAOYSA-M 0.000 abstract 2
- OWXJKYNZGFSVRC-NSCUHMNNSA-N (e)-1-chloroprop-1-ene Chemical compound C\C=C\Cl OWXJKYNZGFSVRC-NSCUHMNNSA-N 0.000 abstract 1
- VFWCMGCRMGJXDK-UHFFFAOYSA-N 1-chlorobutane Chemical compound CCCCCl VFWCMGCRMGJXDK-UHFFFAOYSA-N 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- -1 bromosuccinic acid imide Chemical class 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- WYYQVWLEPYFFLP-UHFFFAOYSA-K chromium(3+);triacetate Chemical compound [Cr+3].CC([O-])=O.CC([O-])=O.CC([O-])=O WYYQVWLEPYFFLP-UHFFFAOYSA-K 0.000 abstract 1
- 230000018044 dehydration Effects 0.000 abstract 1
- 238000006297 dehydration reaction Methods 0.000 abstract 1
- WMIYKQLTONQJES-UHFFFAOYSA-N hexafluoroethane Chemical compound FC(F)(F)C(F)(F)F WMIYKQLTONQJES-UHFFFAOYSA-N 0.000 abstract 1
- OTYBMLCTZGSZBG-UHFFFAOYSA-L potassium sulfate Chemical compound [K+].[K+].[O-]S([O-])(=O)=O OTYBMLCTZGSZBG-UHFFFAOYSA-L 0.000 abstract 1
- 229910052939 potassium sulfate Inorganic materials 0.000 abstract 1
- 235000011151 potassium sulphates Nutrition 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 238000003756 stirring Methods 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
The present invention discloses drug intermediates butyraldehyde oxime drug intermediates synthesis method, comprises the following steps: 1-chlorobutane and potassium sulfate solution were added to the reaction vessel, raised the temperature of the solution, controlled the stirring speed, added aqueous solution and ethyl vinyl ether solution, added bromosuccinic acid imide in batches, continued to react; then added chromium acetate powder, raised the temperature of the solution, continued to react, washed with potassium bromide solution, washed with hexafluoroethane solution, recrystallized in chloropropene solution, dehydrated with dehydration, got the finished product butyraldehyde oxime.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IES20180250 IES87060B2 (en) | 2018-08-16 | 2018-08-16 | Butyraldehyde oxime drug itermediates synthesis method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IES20180250 IES87060B2 (en) | 2018-08-16 | 2018-08-16 | Butyraldehyde oxime drug itermediates synthesis method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IES20180250A2 true IES20180250A2 (en) | 2019-10-30 |
| IES87060B2 IES87060B2 (en) | 2019-10-30 |
Family
ID=68535959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IES20180250 IES87060B2 (en) | 2018-08-16 | 2018-08-16 | Butyraldehyde oxime drug itermediates synthesis method |
Country Status (1)
| Country | Link |
|---|---|
| IE (1) | IES87060B2 (en) |
-
2018
- 2018-08-16 IE IES20180250 patent/IES87060B2/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IES87060B2 (en) | 2019-10-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PH12016502334A1 (en) | Method for producing fused heterocyclic compound | |
| IES20180250A2 (en) | Butyraldehyde oxime drug itermediates synthesis method | |
| IE20180280U1 (en) | Methylchloroperoxybenzoic acid drug intermediates synthesis method | |
| IE20180281U1 (en) | Benzoyl peroxide organic intermediates synthesis method | |
| IES20180267U1 (en) | Aminoquinone drug intermediates tetrachlorobenzoquinone synthesis method | |
| IE20180290U1 (en) | P-aminobenzaldehyde drug intermediates synthesis method | |
| IES20180253U1 (en) | Tert-butyl hydroperoxide drug intermediates synthesis method | |
| IES20180086A2 (en) | Drug intermediates isovaleric acid synthesis method | |
| IES20180293A2 (en) | 1,2-naphthoquinone drug intermediates synthesis method | |
| IES20180251U1 (en) | Nicotinamide-n-oxide drug intermediates synthesis method | |
| IES20180107A2 (en) | Drug intermediates parachlorobenzoic-acid synthesis method | |
| IES20180195A2 (en) | Pharmaceutical hormone intermediates 11-ketone-16α, 17α-epoxy progesterone synthesis method | |
| IE20180288U1 (en) | P-methoxphenylacetic acid drug intermediates synthesis method | |
| IE20180284U1 (en) | 2,3-dihydroxy-succinic acid drug intermediates synthesis method | |
| IE20180282U1 (en) | Dodecanoyl peroxide organic intermediates synthesis method | |
| IES20180096A2 (en) | Organic synthesis intermediates m-aminobenzenesulfonic acid synthesis method | |
| IES20180244U1 (en) | Rubber cross-linking agent cyclohexanone peroxide synthesis method | |
| IE20180283U1 (en) | O-toluene formamide organic intermediates synthesis method | |
| IES20180291A2 (en) | Acetone dicarboxylic acid drug intermediates synthesis method | |
| IES20180262A2 (en) | Drug intermediates 3,5-dimethoxybenzaldehyde synthesis method | |
| IES20180198A2 (en) | Pharmaceutical intermediates 2-acetamido-5-sulfonyl chloride-1,3,4-thiadiazole synthesis method | |
| IES20180117A2 (en) | Drug synthesis intermediates p-carboxybenzenesulfonic amide synthesis method | |
| IES20180113A2 (en) | Drug intermediates p-benzoylbenzoic acid synthesis method | |
| IES20180257U1 (en) | Double hydroxyethyl sulfone organicintermediates synthesis method | |
| IES20180204A2 (en) | Organic intermediates oxalic acid aldehydes synthesis method |