IL143226A0 - Pyrrolidine derivatives-ccr-3 receptor antagonists - Google Patents

Pyrrolidine derivatives-ccr-3 receptor antagonists

Info

Publication number: IL143226A0
Authority: IL; Israel
Prior art keywords: ccr; receptor antagonists; pyrrolidine derivatives; pyrrolidine; derivatives
Prior art date: 1998-11-20

Application number

IL14322699A

Other languages

English (en)

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-11-20

Filing date

1999-11-11

Publication date

2002-04-21

1999-11-11 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2002-04-21 Publication of IL143226A0 publication Critical patent/IL143226A0/xx

Links

RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical class C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 title 3
239000002464 receptor antagonist Substances 0.000 title 1
229940044551 receptor antagonist Drugs 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrrole Compounds (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

IL14322699A 1998-11-20 1999-11-11 Pyrrolidine derivatives-ccr-3 receptor antagonists IL143226A0 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10929798P	1998-11-20	1998-11-20
PCT/EP1999/008665 WO2000031032A1 (en)	1998-11-20	1999-11-11	Pyrrolidine derivatives-ccr-3 receptor antagonists

Publications (1)

Publication Number	Publication Date
IL143226A0 true IL143226A0 (en)	2002-04-21

Family

ID=22326918

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
IL14322699A IL143226A0 (en)	1998-11-20	1999-11-11	Pyrrolidine derivatives-ccr-3 receptor antagonists

Country Status (27)

Country	Link
US (1)	US6166015A (cs)
EP (1)	EP1131288A1 (cs)
JP (1)	JP3593037B2 (cs)
KR (1)	KR20010086045A (cs)
CN (1)	CN1158256C (cs)
AR (1)	AR023707A1 (cs)
AU (1)	AU763960B2 (cs)
BR (1)	BR9915520A (cs)
CA (1)	CA2350903A1 (cs)
CO (1)	CO5140119A1 (cs)
CZ (1)	CZ20011760A3 (cs)
DE (1)	DE19955794A1 (cs)
ES (1)	ES2158814B1 (cs)
FR (1)	FR2786185A1 (cs)
GB (1)	GB2343893B (cs)
HU (1)	HUP0104364A2 (cs)
ID (1)	ID29067A (cs)
IL (1)	IL143226A0 (cs)
IT (1)	IT1307900B1 (cs)
MA (1)	MA26762A1 (cs)
NO (1)	NO20012411D0 (cs)
PE (1)	PE20001403A1 (cs)
PL (1)	PL348375A1 (cs)
TR (1)	TR200101398T2 (cs)
UY (1)	UY25811A1 (cs)
WO (1)	WO2000031032A1 (cs)
ZA (1)	ZA200103942B (cs)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6339087B1 (en)	1997-08-18	2002-01-15	Syntex (U.S.A.) Llc	Cyclic amine derivatives-CCR-3 receptor antagonists
IL125658A0 (en)	1997-08-18	1999-04-11	Hoffmann La Roche	Ccr-3 receptor antagonists
US6316623B1 (en) *	1998-08-21	2001-11-13	Isis Pharmaceuticals, Inc.	Ethylenediamine compound libraries
JP3421323B2 (ja)	1998-11-20	2003-06-30	エフ．ホフマン−ラロシュアーゲー	ピペリジンｃｃｒ−３受容体拮抗薬
CA2373942A1 (en) *	1999-05-18	2000-11-23	Teijin Limited	Remedies or prophylactis for diseases in association with chemokines
CA2378499A1 (en) *	1999-08-04	2001-02-15	Teijin Limited	Cyclic amine ccr3 antagonists
ES2276706T3 (es) *	1999-12-08	2007-07-01	Teijin Limited	Antagonistas del receptor ccr5 de aminas ciclicas.
BR0114321A (pt) *	2000-09-29	2003-07-01	Glaxo Group Ltd	Composto, composição farmacêutica, uso de um composto, método de tratamento ou profilaxia de doenças inflamatórias, e, processo para preparar um composto
EP1324990B1 (en)	2000-09-29	2014-10-29	Glaxo Group Limited	Morpholin-acetamide derivatives for the treatment of inflammatory diseases
ES2292530T3 (es)	2000-12-19	2008-03-16	F. Hoffmann-La Roche Ag	Pirrolidinas sustituidas como antagonistas del receptor ccr-3.
FR2821356A1 (fr) *	2001-02-23	2002-08-30	Cerep	Nouveaux derives d'arylcarbamates et d'arylurees, preparations et utilisations
GB0117387D0 (en) *	2001-07-17	2001-09-05	Novartis Ag	Organic compounds
JP2005502700A (ja) *	2001-09-13	2005-01-27	エフ．ホフマン−ラ　ロシュ　アーゲー	Ｃｃｒ−３受容体アンタゴニストｖ
US7067549B2 (en) *	2001-12-31	2006-06-27	Actelion Pharmaceuticals Ag	Pyrrolidone carboxamides
GB0207432D0 (en) *	2002-03-28	2002-05-08	Glaxo Group Ltd	Novel compounds
GB0207443D0 (en) *	2002-03-28	2002-05-08	Glaxo Group Ltd	Novel compounds
GB0207436D0 (en) *	2002-03-28	2002-05-08	Glaxo Group Ltd	Novel compounds
GB0207439D0 (en) *	2002-03-28	2002-05-08	Glaxo Group Ltd	Novel compounds
GB0212355D0 (en) *	2002-05-29	2002-07-10	Glaxo Group Ltd	Novel compounds
EP1531822B1 (en)	2002-06-12	2009-08-05	ChemoCentryx Inc	1-aryl-4-substituted piperazine derivatives for use as ccr1 antagonists for the treatment of inflammation and immune disorders
US7589199B2 (en)	2002-06-12	2009-09-15	Chemocentryx, Inc.	Substituted piperazines
US7842693B2 (en)	2002-06-12	2010-11-30	Chemocentryx, Inc.	Substituted piperazines
CN1665506A (zh)	2002-07-02	2005-09-07	霍夫曼-拉罗奇有限公司	作为ccr－3受体拮抗剂ⅸ的2,5－取代的嘧啶衍生物
WO2004028530A1 (en) *	2002-09-26	2004-04-08	Bristol-Myers Squibb Company	N-substituted heterocyclic amines as modulators of chemokine receptor activity
ATE440835T1 (de)	2003-03-06	2009-09-15	Glaxo Group Ltd	Heterozyklische harnstoff-derivate für die behandlung von schmerzen.
EP1601665A2 (en)	2003-03-07	2005-12-07	Glaxo Group Limited	Urea derivatives
GB0305426D0 (en) *	2003-03-08	2003-04-16	Glaxo Group Ltd	Novel compounds
RU2366655C2 (ru)	2003-03-14	2009-09-10	Оно Фармасьютикал Ко., Лтд.	Азотсодержащие гетероциклические производные и лекарственные средства, содержащие их в качестве активного ингредиента
WO2004092169A1 (ja)	2003-04-18	2004-10-28	Ono Pharmaceutical Co., Ltd.	スピロピペリジン化合物およびその医薬用途
EP1680408A2 (en) *	2003-10-24	2006-07-19	F. Hoffmann-La Roche Ag	Ccr3 receptor antagonists
US7435830B2 (en)	2004-03-03	2008-10-14	Chemocentryx, Inc.	Bicyclic and bridged nitrogen heterocycles
US7435831B2 (en)	2004-03-03	2008-10-14	Chemocentryx, Inc.	Bicyclic and bridged nitrogen heterocycles
RU2403237C2 (ru) *	2004-05-14	2010-11-10	Эмисфире Текнолоджис, Инк.	Составы и смеси для доставки активных агентов
MXPA06013252A (es) *	2004-05-14	2007-02-28	Emisphere Tech Inc	Compuestos y composiciones para suministrar agentes activos.
US8143404B2 (en)	2004-09-13	2012-03-27	Ono Pharmaceutical Co., Ltd	Nitrogenous heterocylic derivative and medicine containing the same as an active ingredient
US7968539B2 (en)	2005-02-17	2011-06-28	State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Portland State University	Quinoline derivatives and uses thereof
EP1889622A4 (en)	2005-05-31	2009-12-23	Ono Pharmaceutical Co	SPIROPIPERIDINE COMPOUND AND MEDICINAL USE THEREOF
WO2007011292A1 (en) *	2005-07-21	2007-01-25	Astrazeneca Ab	N-benzyl-morpholine derivatives as modulators of the chemokine receptor
KR100743617B1 (ko) *	2005-08-25	2007-07-27	주식회사 알에스텍	고광학순도를 갖는 키랄 3-히드록시 피롤리딘 및 그유도체를 제조하는 방법
BRPI0616150A2 (pt) *	2005-09-22	2011-06-07	Sanofi Aventis	derivados de amino-alquil-amida como lìquidos receptores de ccr3
HUP0500877A2 (en) *	2005-09-22	2007-05-29	Sanofi Aventis	Amide derivatives as ccr3 receptor ligands, process for producing them, pharmaceutical compositions containing them and their use and intermediates
HUP0500879A2 (en) *	2005-09-22	2007-05-29	Sanofi Aventis	Amide derivatives as ccr3 receptor ligands, process for producing them, pharmaceutical compositions containing them and their use and intermediates
HUP0500886A2 (en) *	2005-09-23	2007-05-29	Sanofi Aventis	Amide derivatives as ccr3 receptor ligands, process for producing them, pharmaceutical compositions containing them and their use
EP2657235A1 (en)	2005-10-28	2013-10-30	Ono Pharmaceutical Co., Ltd.	Compound containing basic group and use thereof
WO2007058322A1 (ja)	2005-11-18	2007-05-24	Ono Pharmaceutical Co., Ltd.	塩基性基を含有する化合物およびその用途
CA2644368A1 (en)	2006-03-10	2007-09-20	Ono Pharmaceutical Co., Ltd.	Nitrogenated heterocyclic derivative, and pharmaceutical agent comprising the derivative as active ingredient
WO2007132846A1 (ja)	2006-05-16	2007-11-22	Ono Pharmaceutical Co., Ltd.	保護されていてもよい酸性基を含有する化合物およびその用途
JP5245827B2 (ja)	2006-07-31	2013-07-24	小野薬品工業株式会社	スピロ結合した環状基を含有する化合物およびその用途
WO2010129351A1 (en)	2009-04-28	2010-11-11	Schepens Eye Research Institute	Method to identify and treat age-related macular degeneration
CN101906060B (zh) *	2010-05-06	2012-07-04	爱斯医药科技(南京)有限公司	N-取代的3-氨甲基吡咯烷的制备方法

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3459757A (en) *	1965-10-22	1969-08-05	American Cyanamid Co	Imidazolidines
NZ186175A (en) *	1977-01-27	1980-03-05	Shionogi & Co	Meta-sulphonamidobenzamide derivatives
JPS59186969A (ja) *	1983-04-08	1984-10-23	Yoshitomi Pharmaceut Ind Ltd	ベンゾフラン−およびベンゾピランカルボキサミド誘導体
FI95572C (fi) *	1987-06-22	1996-02-26	Eisai Co Ltd	Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi
JPH01117860A (ja) *	1987-10-30	1989-05-10	Dainippon Pharmaceut Co Ltd	安息香酸アミド誘導体
JPH02104572A (ja) *	1988-10-13	1990-04-17	Dainippon Pharmaceut Co Ltd	安息香酸アミド誘導体
US5214055A (en) *	1990-05-18	1993-05-25	Adir Et Compagnie	Aminopiperidine 4-oxo-4H-chromen-2-yl compounds
FR2662162B1 (fr) *	1990-05-18	1995-01-20	Adir	Nouveaux derives de l'amino piperidine, de l'amino pyrrolidine et de l'amino perhydroazepine, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5254569A (en) *	1991-01-14	1993-10-19	The Du Pont Merck Pharmaceutical Company	(Amidomethyl)nitrogen heterocyclic analgesics
GB9113031D0 (en) *	1991-06-17	1991-08-07	Smithkline Beecham Plc	Compounds
FR2679906B1 (fr) *	1991-07-31	1995-01-20	Adir	Nouvelles (isoquinolein-5 yl) sulfonamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
WO1993003725A1 (en) *	1991-08-20	1993-03-04	Smithkline Beecham Plc	5-ht4 receptor antagonists
JPH06212757A (ja) *	1993-01-19	1994-08-02	Ribaa Kentetsu Kk	ソリ型運搬治具による折板屋根葺き工法
EP0742208A1 (en) *	1995-05-05	1996-11-13	Grelan Pharmaceutical Co., Ltd.	2-Ureido-benzamide derivatives
US5827875A (en) *	1996-05-10	1998-10-27	Bristol-Myers Squibb Company	Inhibitors of microsomal triglyceride transfer protein and method
EP0916668A4 (en) *	1996-07-29	2000-08-16	Banyu Pharma Co Ltd	CHEMOKIN RECEPTOR ANTAGONISTS
IL125658A0 (en) *	1997-08-18	1999-04-11	Hoffmann La Roche	Ccr-3 receptor antagonists
JPH11140276A (ja) *	1997-11-11	1999-05-25	Sumitomo Chem Co Ltd	多官能シアン酸エステル樹脂組成物および樹脂封止型半導体装置
SK285729B6 (sk) *	1997-11-18	2007-07-06	Teijin Pharma Limited	Zlúčenina derivátov cyklických amínov a jej použitie

1999
- 1999-11-11 IL IL14322699A patent/IL143226A0/xx unknown
- 1999-11-11 KR KR1020017006362A patent/KR20010086045A/ko not_active Ceased
- 1999-11-11 BR BR9915520-6A patent/BR9915520A/pt not_active IP Right Cessation
- 1999-11-11 CA CA002350903A patent/CA2350903A1/en not_active Abandoned
- 1999-11-11 ID IDW00200101080A patent/ID29067A/id unknown
- 1999-11-11 CN CNB99813287XA patent/CN1158256C/zh not_active Expired - Fee Related
- 1999-11-11 WO PCT/EP1999/008665 patent/WO2000031032A1/en not_active Ceased
- 1999-11-11 JP JP2000583860A patent/JP3593037B2/ja not_active Expired - Fee Related
- 1999-11-11 PL PL99348375A patent/PL348375A1/xx not_active Application Discontinuation
- 1999-11-11 CZ CZ20011760A patent/CZ20011760A3/cs unknown
- 1999-11-11 AU AU13825/00A patent/AU763960B2/en not_active Ceased
- 1999-11-11 TR TR2001/01398T patent/TR200101398T2/xx unknown
- 1999-11-11 EP EP99972623A patent/EP1131288A1/en not_active Withdrawn
- 1999-11-11 HU HU0104364A patent/HUP0104364A2/hu unknown
- 1999-11-16 PE PE1999001161A patent/PE20001403A1/es not_active Application Discontinuation
- 1999-11-17 GB GB9927227A patent/GB2343893B/en not_active Expired - Fee Related
- 1999-11-18 AR ARP990105860A patent/AR023707A1/es unknown
- 1999-11-18 CO CO99072639A patent/CO5140119A1/es unknown
- 1999-11-18 US US09/442,656 patent/US6166015A/en not_active Expired - Fee Related
- 1999-11-18 FR FR9914495A patent/FR2786185A1/fr not_active Withdrawn
- 1999-11-19 IT IT1999TO001009A patent/IT1307900B1/it active
- 1999-11-19 DE DE19955794A patent/DE19955794A1/de not_active Withdrawn
- 1999-11-19 UY UY25811A patent/UY25811A1/es unknown
- 1999-11-19 ES ES009902547A patent/ES2158814B1/es not_active Expired - Lifetime
2001
- 2001-05-15 ZA ZA200103942A patent/ZA200103942B/en unknown
- 2001-05-16 NO NO20012411A patent/NO20012411D0/no not_active Application Discontinuation
- 2001-05-17 MA MA26199A patent/MA26762A1/fr unknown

Also Published As

Publication number	Publication date
JP2002530374A (ja)	2002-09-17
ZA200103942B (en)	2002-08-15
CN1331677A (zh)	2002-01-16
KR20010086045A (ko)	2001-09-07
BR9915520A (pt)	2001-07-17
EP1131288A1 (en)	2001-09-12
NO20012411L (no)	2001-05-16
GB2343893A (en)	2000-05-24
ID29067A (id)	2001-07-26
US6166015A (en)	2000-12-26
IT1307900B1 (it)	2001-11-19
CZ20011760A3 (cs)	2001-12-12
ITTO991009A1 (it)	2001-05-19
PE20001403A1 (es)	2000-12-15
AU1382500A (en)	2000-06-13
JP3593037B2 (ja)	2004-11-24
CA2350903A1 (en)	2000-06-02
AU763960B2 (en)	2003-08-07
NO20012411D0 (no)	2001-05-16
DE19955794A1 (de)	2000-05-31
AR023707A1 (es)	2002-09-04
GB9927227D0 (en)	2000-01-12
ITTO991009A0 (it)	1999-11-19
FR2786185A1 (fr)	2000-05-26
TR200101398T2 (tr)	2001-09-21
PL348375A1 (en)	2002-05-20
MA26762A1 (fr)	2004-12-20
ES2158814B1 (es)	2002-03-16
CO5140119A1 (es)	2002-03-22
GB2343893B (en)	2002-01-09
HUP0104364A2 (hu)	2002-04-29
ES2158814A1 (es)	2001-09-01
WO2000031032A1 (en)	2000-06-02
CN1158256C (zh)	2004-07-21
UY25811A1 (es)	2001-07-31

Publication	Publication Date	Title
IL143226A0 (en)	2002-04-21	Pyrrolidine derivatives-ccr-3 receptor antagonists
GB2343891B (en)	2001-05-30	4-Aroyl-piperidine CCR-3 receptor antagonists
HU9603525D0 (en)	1997-02-28	Vironectin receptor antagonists
EP1105389A4 (en)	2001-10-17	INTEGRIN RECEPTOR ANTAGONISTS
EP0912175A4 (en)	1999-09-08	FIBRINOGENIC RECEPTOR ANTAGONISTS
GB9927228D0 (en)	2000-01-12	CCR-3 receptor antagonists II
SG80041A1 (en)	2001-04-17	Muscarinic receptor antagonists
EP0885213A4 (en)	1999-04-28	FIBRINOGEN RECEPTOR ANTAGONISTS
IL135797A0 (en)	2001-05-20	Thrombin receptor antagonists
IL140249A0 (en)	2002-02-10	Muscarinic antagonists
GB9826359D0 (en)	1999-01-27	Novel receptors
IL146151A0 (en)	2002-07-25	Human-g-protein receptor
GB9820014D0 (en)	1998-11-04	Receptor antagonists and uses thereof
EP1084142A4 (en)	2005-01-19	GPR35A RECEIVER
EP1047424A4 (en)	2002-05-22	IL-8 RECEPTOR ANTAGONISTS
EP1039903A4 (en)	2001-12-05	INTERLEUKIN-8 RECEPTOR ANTAGONISTS
GB9819420D0 (en)	1998-10-28	Novel receptor
EP1131335A4 (en)	2002-07-31	7TM RECEPTOR HLWAR77
GB0026327D0 (en)	2000-12-13	Thrombin receptor antagonists
EP1083909A4 (en)	2002-01-02	hCEPR RECEPTOR
EP1109565A4 (en)	2004-05-19	GABAB1AA RECEPTOR
GB9811283D0 (en)	1998-07-22	Vironectin receptor antagonists
IL140983A0 (en)	2002-02-10	Il-8 receptor antagonists
GB9708766D0 (en)	1997-06-25	Fibrinogen receptor antagonist
GB9825849D0 (en)	1999-01-20	Receptor