IT1304152B1 - Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato - Google Patents

Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato

Info

Publication number
IT1304152B1
IT1304152B1 IT1998MI002655A ITMI982655A IT1304152B1 IT 1304152 B1 IT1304152 B1 IT 1304152B1 IT 1998MI002655 A IT1998MI002655 A IT 1998MI002655A IT MI982655 A ITMI982655 A IT MI982655A IT 1304152 B1 IT1304152 B1 IT 1304152B1
Authority
IT
Italy
Prior art keywords
peptide
polylactic
preparation
glycolic acid
prolonged
Prior art date
Application number
IT1998MI002655A
Other languages
English (en)
Inventor
Alain Maquin
Patrice Mauriac
Pierre Marion
Original Assignee
Mediolanum Farmaceutici Srl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to IT1998MI002655A priority Critical patent/IT1304152B1/it
Application filed by Mediolanum Farmaceutici Srl filed Critical Mediolanum Farmaceutici Srl
Priority to BRPI9916053-6A priority patent/BR9916053B1/pt
Priority to EP99963398A priority patent/EP1137400B1/en
Priority to CNB998142417A priority patent/CN1149975C/zh
Priority to DE69912836T priority patent/DE69912836T2/de
Priority to CA002354034A priority patent/CA2354034C/en
Priority to US09/857,404 priority patent/US6620422B1/en
Priority to JP2000586303A priority patent/JP4607329B2/ja
Priority to KR1020017006407A priority patent/KR100676844B1/ko
Priority to ES99963398T priority patent/ES2211211T3/es
Priority to AU19711/00A priority patent/AU757898C/en
Priority to PT99963398T priority patent/PT1137400E/pt
Priority to PCT/EP1999/009536 priority patent/WO2000033809A1/en
Priority to DK99963398T priority patent/DK1137400T3/da
Priority to AT99963398T priority patent/ATE253893T1/de
Priority to TW088121636A priority patent/TW561053B/zh
Publication of ITMI982655A1 publication Critical patent/ITMI982655A1/it
Application granted granted Critical
Publication of IT1304152B1 publication Critical patent/IT1304152B1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
IT1998MI002655A 1998-12-10 1998-12-10 Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato IT1304152B1 (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT1998MI002655A IT1304152B1 (it) 1998-12-10 1998-12-10 Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato
AU19711/00A AU757898C (en) 1998-12-10 1999-12-06 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period
CNB998142417A CN1149975C (zh) 1998-12-10 1999-12-06 适合于制备具有延长释放期限的皮下植入物的含有一种肽和聚乳酸-乙醇酸的组合物
DE69912836T DE69912836T2 (de) 1998-12-10 1999-12-06 Zusammensetzungen enthaltend ein peptid und polymilch-glykolsäure geeignet für die herstellung von subkutanen implantaten mit verlängerter wirkstoffabgabe
CA002354034A CA2354034C (en) 1998-12-10 1999-12-06 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period
US09/857,404 US6620422B1 (en) 1998-12-10 1999-12-06 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period
JP2000586303A JP4607329B2 (ja) 1998-12-10 1999-12-06 放出時間が延長された皮下インプラントを製造するのに適したペプチドとポリ乳酸グリコール酸とを含む組成物
KR1020017006407A KR100676844B1 (ko) 1998-12-10 1999-12-06 방출 기간이 연장된 피하 삽입물을 제조하기에 적당한펩티드와 폴리락트산-글리콜산을 포함하는 조성물
BRPI9916053-6A BR9916053B1 (pt) 1998-12-10 1999-12-06 composições contendo um peptìdeo e um ácido glicólico poliláctico, adequadas para preparação de implantes subcutáneos com perìodo de liberação prolongado.
EP99963398A EP1137400B1 (en) 1998-12-10 1999-12-06 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period toff, verfahren zu seiner herstellung und anlage zur durchfuhrung des verfahrens
PT99963398T PT1137400E (pt) 1998-12-10 1999-12-06 Composicoes contendo um peptideo e um acido polilactico-glicolico apropriado para preparar implantes subscutaneos com um periodo de libertacao prolongado
PCT/EP1999/009536 WO2000033809A1 (en) 1998-12-10 1999-12-06 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extended release period
DK99963398T DK1137400T3 (da) 1998-12-10 1999-12-06 Præparater indeholdende et peptid og polymælkesyre-glycolsyre egnet til fremstilling af subkutane implantater med en forlænget frigivelsesperiode
AT99963398T ATE253893T1 (de) 1998-12-10 1999-12-06 Zusammensetzungen enthaltend ein peptid und polymilch-glykolsäure geeignet für die herstellung von subkutanen implantaten mit verlängerter wirkstoffabgabe
ES99963398T ES2211211T3 (es) 1998-12-10 1999-12-06 Composiciones que contienen un peptido y un acido polilactico-glicolico, adecuadas para preparar implantes subcutaneos con duracion prolongada de liberacion.
TW088121636A TW561053B (en) 1998-12-10 2000-03-08 Compositions containing a peptide and polylactic-glycolic acid suitable for preparing subcutaneous implants with an extender release period

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT1998MI002655A IT1304152B1 (it) 1998-12-10 1998-12-10 Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato

Publications (2)

Publication Number Publication Date
ITMI982655A1 ITMI982655A1 (it) 2000-06-10
IT1304152B1 true IT1304152B1 (it) 2001-03-08

Family

ID=11381206

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1998MI002655A IT1304152B1 (it) 1998-12-10 1998-12-10 Composizioni comprendenti un peptide ed acido polilattico-glicolicoatte alla preparazione di impianti sottocutanei aventi un prolungato

Country Status (16)

Country Link
US (1) US6620422B1 (it)
EP (1) EP1137400B1 (it)
JP (1) JP4607329B2 (it)
KR (1) KR100676844B1 (it)
CN (1) CN1149975C (it)
AT (1) ATE253893T1 (it)
AU (1) AU757898C (it)
BR (1) BR9916053B1 (it)
CA (1) CA2354034C (it)
DE (1) DE69912836T2 (it)
DK (1) DK1137400T3 (it)
ES (1) ES2211211T3 (it)
IT (1) IT1304152B1 (it)
PT (1) PT1137400E (it)
TW (1) TW561053B (it)
WO (1) WO2000033809A1 (it)

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ITMI20061545A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Particelle in grado di rilasciare il principio attivo per un periodo prolungato di tempo
ITMI20061538A1 (it) * 2006-08-02 2008-02-03 Mediolanum Pharmaceuticals Ltd Impianti sottocutanei in grado di rilasciare il principio attivo per un periodo prolungato di tempo
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Also Published As

Publication number Publication date
DE69912836D1 (de) 2003-12-18
BR9916053A (pt) 2001-09-04
DE69912836T2 (de) 2004-11-11
ITMI982655A1 (it) 2000-06-10
ES2211211T3 (es) 2004-07-01
DK1137400T3 (da) 2004-03-22
KR100676844B1 (ko) 2007-01-31
CN1149975C (zh) 2004-05-19
CA2354034C (en) 2009-01-27
PT1137400E (pt) 2004-03-31
EP1137400A1 (en) 2001-10-04
AU757898B2 (en) 2003-03-13
CN1329485A (zh) 2002-01-02
BR9916053B1 (pt) 2011-04-19
AU757898C (en) 2003-12-18
JP4607329B2 (ja) 2011-01-05
AU1971100A (en) 2000-06-26
EP1137400B1 (en) 2003-11-12
KR20010082310A (ko) 2001-08-29
CA2354034A1 (en) 2000-06-15
TW561053B (en) 2003-11-11
ATE253893T1 (de) 2003-11-15
JP2002531486A (ja) 2002-09-24
WO2000033809A1 (en) 2000-06-15
US6620422B1 (en) 2003-09-16

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