JPS604162A - ビス〔４−（アミノフェノキシ）フェニル〕スルホンの精製法 - Google Patents

ビス〔４−（アミノフェノキシ）フェニル〕スルホンの精製法

Info

Publication number: JPS604162A
Authority: JP; Japan
Prior art keywords: sulfone; aminophenoxy; phenyl; bis; solution
Prior art date: 1983-06-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

JP11228483A

Other languages

English (en)

Japanese (ja)

Other versions

JPH0379341B2 (2

Inventor

Yukichi Morita

守田　諭吉

Kazuo Hamano

浜野　和夫

Eiji Ogata

栄治尾形

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Konishi Chemical Ind Co Ltd

Original Assignee

Konishi Chemical Ind Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-06-22

Filing date

1983-06-22

Publication date

1985-01-10

1983-06-22 Application filed by Konishi Chemical Ind Co Ltd filed Critical Konishi Chemical Ind Co Ltd

1983-06-22 Priority to JP11228483A priority Critical patent/JPS604162A/ja

1985-01-10 Publication of JPS604162A publication Critical patent/JPS604162A/ja

1991-12-18 Publication of JPH0379341B2 publication Critical patent/JPH0379341B2/ja

Status Granted legal-status Critical Current

Links

FJYCAYKHNVQCJW-UHFFFAOYSA-N 2-[4-[4-(2-aminophenoxy)phenyl]sulfonylphenoxy]aniline Chemical compound NC1=CC=CC=C1OC1=CC=C(S(=O)(=O)C=2C=CC(OC=3C(=CC=CC=3)N)=CC=2)C=C1 FJYCAYKHNVQCJW-UHFFFAOYSA-N 0.000 title claims abstract description 14
238000000746 purification Methods 0.000 title claims description 6
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims abstract description 20
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 11
150000003457 sulfones Chemical class 0.000 claims abstract description 8
238000010438 heat treatment Methods 0.000 claims abstract description 7
239000012535 impurity Substances 0.000 claims abstract description 6
IXCSERBJSXMMFS-UHFFFAOYSA-N hydrogen chloride Substances Cl.Cl IXCSERBJSXMMFS-UHFFFAOYSA-N 0.000 claims abstract description 3
229910000041 hydrogen chloride Inorganic materials 0.000 claims abstract description 3
OIJXXZFOLPVYOZ-UHFFFAOYSA-N 2-[4-[4-(2-aminophenoxy)phenyl]sulfonylphenoxy]aniline;hydrochloride Chemical compound Cl.NC1=CC=CC=C1OC1=CC=C(S(=O)(=O)C=2C=CC(OC=3C(=CC=CC=3)N)=CC=2)C=C1 OIJXXZFOLPVYOZ-UHFFFAOYSA-N 0.000 claims abstract 2
239000012043 crude product Substances 0.000 claims description 11
238000000034 method Methods 0.000 claims description 10
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 5
239000003513 alkali Substances 0.000 claims description 2
238000006386 neutralization reaction Methods 0.000 claims description 2
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract description 6
150000001875 compounds Chemical class 0.000 abstract description 4
239000002994 raw material Substances 0.000 abstract description 2
239000000243 solution Substances 0.000 abstract 3
239000007864 aqueous solution Substances 0.000 abstract 1
238000001816 cooling Methods 0.000 abstract 1
229920000642 polymer Polymers 0.000 abstract 1
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
KZTYYGOKRVBIMI-UHFFFAOYSA-N diphenyl sulfone Chemical compound C=1C=CC=CC=1S(=O)(=O)C1=CC=CC=C1 KZTYYGOKRVBIMI-UHFFFAOYSA-N 0.000 description 6
239000000047 product Substances 0.000 description 5
238000004519 manufacturing process Methods 0.000 description 4
238000002844 melting Methods 0.000 description 4
230000008018 melting Effects 0.000 description 4
KFZMGEQAYNKOFK-UHFFFAOYSA-N Isopropanol Chemical compound CC(C)O KFZMGEQAYNKOFK-UHFFFAOYSA-N 0.000 description 3
KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 description 3
238000001914 filtration Methods 0.000 description 3
238000004128 high performance liquid chromatography Methods 0.000 description 3
239000003960 organic solvent Substances 0.000 description 3
CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 2
230000000052 comparative effect Effects 0.000 description 2
238000004090 dissolution Methods 0.000 description 2
239000000706 filtrate Substances 0.000 description 2
239000002244 precipitate Substances 0.000 description 2
235000011121 sodium hydroxide Nutrition 0.000 description 2
238000003756 stirring Methods 0.000 description 2
239000000126 substance Substances 0.000 description 2
VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
CDAWCLOXVUBKRW-UHFFFAOYSA-N 2-aminophenol Chemical compound NC1=CC=CC=C1O CDAWCLOXVUBKRW-UHFFFAOYSA-N 0.000 description 1
QCQCHGYLTSGIGX-GHXANHINSA-N 4-[[(3ar,5ar,5br,7ar,9s,11ar,11br,13as)-5a,5b,8,8,11a-pentamethyl-3a-[(5-methylpyridine-3-carbonyl)amino]-2-oxo-1-propan-2-yl-4,5,6,7,7a,9,10,11,11b,12,13,13a-dodecahydro-3h-cyclopenta[a]chrysen-9-yl]oxy]-2,2-dimethyl-4-oxobutanoic acid Chemical compound N([C@@]12CC[C@@]3(C)[C@]4(C)CC[C@H]5C(C)(C)[C@@H](OC(=O)CC(C)(C)C(O)=O)CC[C@]5(C)[C@H]4CC[C@@H]3C1=C(C(C2)=O)C(C)C)C(=O)C1=CN=CC(C)=C1 QCQCHGYLTSGIGX-GHXANHINSA-N 0.000 description 1
VHUUQVKOLVNVRT-UHFFFAOYSA-N Ammonium hydroxide Chemical compound [NH4+].[OH-] VHUUQVKOLVNVRT-UHFFFAOYSA-N 0.000 description 1
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
-1 aminophenoxy Chemical group 0.000 description 1
235000011114 ammonium hydroxide Nutrition 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
238000004040 coloring Methods 0.000 description 1
230000000694 effects Effects 0.000 description 1
150000003840 hydrochlorides Chemical class 0.000 description 1
230000003472 neutralizing effect Effects 0.000 description 1
235000011118 potassium hydroxide Nutrition 0.000 description 1
238000001953 recrystallisation Methods 0.000 description 1
235000017550 sodium carbonate Nutrition 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
239000002904 solvent Substances 0.000 description 1

Landscapes

Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

JP11228483A 1983-06-22 1983-06-22 ビス〔４−（アミノフェノキシ）フェニル〕スルホンの精製法 Granted JPS604162A (ja)

Priority Applications (1)

Application Number	Priority Date	Filing Date	Title
JP11228483A JPS604162A (ja)	1983-06-22	1983-06-22	ビス〔４−（アミノフェノキシ）フェニル〕スルホンの精製法

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
JP11228483A JPS604162A (ja)	1983-06-22	1983-06-22	ビス〔４−（アミノフェノキシ）フェニル〕スルホンの精製法

Publications (2)

Publication Number	Publication Date
JPS604162A true JPS604162A (ja)	1985-01-10
JPH0379341B2 JPH0379341B2 (2)	1991-12-18

Family

ID=14582837

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP11228483A Granted JPS604162A (ja)	1983-06-22	1983-06-22	ビス〔４−（アミノフェノキシ）フェニル〕スルホンの精製法

Country Status (1)

Country	Link
JP (1)	JPS604162A (2)

1983
- 1983-06-22 JP JP11228483A patent/JPS604162A/ja active Granted

Also Published As

Publication number	Publication date
JPH0379341B2 (2)	1991-12-18

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