JPS604199B2 - アニリン系ジペプチド誘導体の製造法 - Google Patents

アニリン系ジペプチド誘導体の製造法

Info

Publication number
JPS604199B2
JPS604199B2 JP49090565A JP9056574A JPS604199B2 JP S604199 B2 JPS604199 B2 JP S604199B2 JP 49090565 A JP49090565 A JP 49090565A JP 9056574 A JP9056574 A JP 9056574A JP S604199 B2 JPS604199 B2 JP S604199B2
Authority
JP
Japan
Prior art keywords
group
acid
formula
hydrogen
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP49090565A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5126853A (fr
Inventor
健太郎 平井
暉之 石破
和幸 笹倉
裕彦 杉本
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP49090565A priority Critical patent/JPS604199B2/ja
Priority to ZA00754877A priority patent/ZA754877B/xx
Priority to CA000232782A priority patent/CA1181065A/fr
Priority to NLAANVRAGE7509258,A priority patent/NL175789C/xx
Priority to ES440032A priority patent/ES440032A1/es
Priority to AR259900A priority patent/AR213076A1/es
Priority to DK356475A priority patent/DK155088C/da
Priority to CH1020275A priority patent/CH617668A5/de
Priority to MX000859U priority patent/MX3332E/es
Priority to SE7508829A priority patent/SE427030B/xx
Priority to HU75SI1485A priority patent/HU176016B/hu
Priority to GB32916/75A priority patent/GB1511669A/en
Priority to DD187724A priority patent/DD119213A5/xx
Priority to FR7524559A priority patent/FR2281131A1/fr
Priority to BE158997A priority patent/BE832190A/fr
Priority to AU83734/75A priority patent/AU491928B2/en
Priority to DE2535171A priority patent/DE2535171C3/de
Publication of JPS5126853A publication Critical patent/JPS5126853A/ja
Priority to US05/716,265 priority patent/US4076702A/en
Priority to US05/716,266 priority patent/US4076703A/en
Priority to US05/716,268 priority patent/US4076705A/en
Priority to US05/716,267 priority patent/US4076704A/en
Priority to ES455504A priority patent/ES455504A1/es
Priority to ES455505A priority patent/ES455505A1/es
Priority to ES455506A priority patent/ES455506A1/es
Priority to ES455507A priority patent/ES455507A1/es
Priority to US05/775,646 priority patent/US4240957A/en
Priority to AR270151A priority patent/AR213453A1/es
Priority to AR270152A priority patent/AR215035A1/es
Priority to AR270154A priority patent/AR219307A1/es
Priority to AR270153A priority patent/AR220325A1/es
Priority to US05/867,605 priority patent/US4154727A/en
Priority to CH461779A priority patent/CH627438A5/de
Priority to CH461879A priority patent/CH627439A5/de
Priority to CH827079A priority patent/CH627440A5/de
Priority to CA339,232A priority patent/CA1091652A/fr
Publication of JPS604199B2 publication Critical patent/JPS604199B2/ja
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06017—Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026—Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP49090565A 1974-08-06 1974-08-06 アニリン系ジペプチド誘導体の製造法 Expired JPS604199B2 (ja)

Priority Applications (35)

Application Number Priority Date Filing Date Title
JP49090565A JPS604199B2 (ja) 1974-08-06 1974-08-06 アニリン系ジペプチド誘導体の製造法
ZA00754877A ZA754877B (en) 1974-08-06 1975-07-29 Dipeptide derivatives and their production
CA000232782A CA1181065A (fr) 1974-08-06 1975-07-31 Derives de dipeptide et methode de production
NLAANVRAGE7509258,A NL175789C (nl) 1974-08-06 1975-08-04 Werkwijze voor het bereiden van een farmaceutisch preparaat met kalmerende werking en werkwijze voor het bereiden van geneeskrachtige aminozuur-aniliden.
CH1020275A CH617668A5 (fr) 1974-08-06 1975-08-05
AR259900A AR213076A1 (es) 1974-08-06 1975-08-05 Procedimiento para la produccion de derivados de la glicilglicilanilida sustituida
DK356475A DK155088C (da) 1974-08-06 1975-08-05 Analogifremgangsmaade til fremstilling af benzophenonsubstituerede dipeptidderivater eller syreadditionssalte deraf
ES440032A ES440032A1 (es) 1974-08-06 1975-08-05 Procedimiento para preparar derivados de dipeptido.
MX000859U MX3332E (es) 1974-08-06 1975-08-05 Procedimiento para la preparacion de derivados de dipeptido
SE7508829A SE427030B (sv) 1974-08-06 1975-08-05 Forfarande for framstellning av bensofenonderivat med antikonvulsiv verkan
HU75SI1485A HU176016B (en) 1974-08-06 1975-08-05 Process for producing dipeptide derivatives
GB32916/75A GB1511669A (en) 1974-08-06 1975-08-06 Dipeptide derivatives and their production
DD187724A DD119213A5 (fr) 1974-08-06 1975-08-06
FR7524559A FR2281131A1 (fr) 1974-08-06 1975-08-06 Derives de dipeptide et leur preparation
BE158997A BE832190A (fr) 1974-08-06 1975-08-06 Derives dipeptidiques et leur production
AU83734/75A AU491928B2 (en) 1974-08-06 1975-08-06 Dipeptide derivatives and their production
DE2535171A DE2535171C3 (de) 1974-08-06 1975-08-06 Benzophenon-Derivate und diese Verbindungen enthaltende Arzneimittel
US05/716,265 US4076702A (en) 1974-08-06 1976-08-20 Dipeptide derivatives and their production
US05/716,267 US4076704A (en) 1974-08-06 1976-08-20 Dipeptide derivatives and their production
US05/716,266 US4076703A (en) 1974-08-06 1976-08-20 Dipeptide derivatives and their production
US05/716,268 US4076705A (en) 1974-08-06 1976-08-20 Dipeptide derivatives and their production
ES455504A ES455504A1 (es) 1974-08-06 1977-01-31 Procedimiento para preparar derivados de dipeptido.
ES455505A ES455505A1 (es) 1974-08-06 1977-01-31 Procedimiento para preparar derivados de dipeptido.
ES455506A ES455506A1 (es) 1974-08-06 1977-01-31 Procedimiento para preparar derivados de dipeptido.
ES455507A ES455507A1 (es) 1974-08-06 1977-01-31 Procedimiento para preparar derivados de dipeptido.
US05/775,646 US4240957A (en) 1974-08-06 1977-03-07 Dipeptide derivatives and their production
AR270153A AR220325A1 (es) 1974-08-06 1977-11-28 Procedimiento para la preparacion de derivados de la glicil-glicil-2-benzoil-5-haloanilida y sus sales
AR270151A AR213453A1 (es) 1974-08-06 1977-11-28 Procedimiento para la preparacion de derivados de la glicilglicilanilida sustituida
AR270152A AR215035A1 (es) 1974-08-06 1977-11-28 Procedimiento para la preparacion de derivados de 2-benzoil-n-alquilo(c1-c6)-n-a-(glicil)glicinanilida
AR270154A AR219307A1 (es) 1974-08-06 1977-11-28 Procedimiento para la preparacion de derivados de 2-benxoil-n alpha-glicil-glicil o n alpha-a-fenilalanilglicilanilida
US05/867,605 US4154727A (en) 1974-08-06 1978-01-06 Dipeptide derivatives and their production
CH461779A CH627438A5 (de) 1974-08-06 1979-05-17 Verfahren zur herstellung von dipeptid-derivaten.
CH461879A CH627439A5 (de) 1974-08-06 1979-05-17 Verfahren zur herstellung von dipeptid-derivaten.
CH827079A CH627440A5 (de) 1974-08-06 1979-09-12 Verfahren zur herstellung von dipeptid-derivaten.
CA339,232A CA1091652A (fr) 1974-08-06 1979-11-06 Derives dipeptidiques et procede de production

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP49090565A JPS604199B2 (ja) 1974-08-06 1974-08-06 アニリン系ジペプチド誘導体の製造法

Publications (2)

Publication Number Publication Date
JPS5126853A JPS5126853A (fr) 1976-03-05
JPS604199B2 true JPS604199B2 (ja) 1985-02-01

Family

ID=14001941

Family Applications (1)

Application Number Title Priority Date Filing Date
JP49090565A Expired JPS604199B2 (ja) 1974-08-06 1974-08-06 アニリン系ジペプチド誘導体の製造法

Country Status (3)

Country Link
JP (1) JPS604199B2 (fr)
BE (1) BE832190A (fr)
ZA (1) ZA754877B (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109678751A (zh) * 2019-01-07 2019-04-26 广州同隽医药科技有限公司 一种含有二苯甲烷结构的化合物

Also Published As

Publication number Publication date
BE832190A (fr) 1975-12-01
ZA754877B (en) 1976-07-28
JPS5126853A (fr) 1976-03-05

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