JPS61148181A - Ｆｒ―９００５０６物質およびその製造法 - Google Patents

Ｆｒ―９００５０６物質およびその製造法

Info

Publication number
JPS61148181A
JPS61148181A JP27204285A JP27204285A JPS61148181A JP S61148181 A JPS61148181 A JP S61148181A JP 27204285 A JP27204285 A JP 27204285A JP 27204285 A JP27204285 A JP 27204285A JP S61148181 A JPS61148181 A JP S61148181A
Authority
JP
Japan
Prior art keywords
group
formula
substance
hydroxy group
hydroxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP27204285A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0338276B2 (2
Inventor
Masakuni Okuhara
奥原　正国
Hirokazu Tanaka
田中　洋和
Toshio Goto
後藤　俊男
Toru Kino
亨 木野
Hiroshi Hatanaka
洋 畑中
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fujisawa Pharmaceutical Co Ltd
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of JPS61148181A publication Critical patent/JPS61148181A/ja
Publication of JPH0338276B2 publication Critical patent/JPH0338276B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP27204285A 1984-12-03 1985-12-03 Ｆｒ―９００５０６物質およびその製造法 Granted JPS61148181A (ja)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB8430455 1984-12-03
GB848430455A GB8430455D0 (en) 1984-12-03 1984-12-03 Fr-900506 substance
GB8502869 1985-02-05
GB8508420 1985-04-01

Related Child Applications (2)

Application Number Title Priority Date Filing Date
JP2204518A Division JPH0372483A (ja) 1984-12-03 1990-07-31 免疫抑制剤
JP2204519A Division JPH0720970B2 (ja) 1984-12-03 1990-07-31 トリシクロ化合物

Publications (2)

Publication Number Publication Date
JPS61148181A true JPS61148181A (ja) 1986-07-05
JPH0338276B2 JPH0338276B2 (2) 1991-06-10

Family

ID=10570610

Family Applications (1)

Application Number Title Priority Date Filing Date
JP27204285A Granted JPS61148181A (ja) 1984-12-03 1985-12-03 Ｆｒ―９００５０６物質およびその製造法

Country Status (3)

Country Link
JP (1) JPS61148181A (2)
GB (1) GB8430455D0 (2)
ZA (1) ZA858867B (2)

Cited By (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0192659A (ja) * 1987-06-05 1989-04-11 Fujisawa Pharmaceut Co Ltd 抗ｆｒ−９００５０６物質抗体、および高感度酵素免疫測定法
JPH0219320A (ja) * 1988-01-07 1990-01-23 Merck & Co Inc 新規免疫抑制剤
JPH0372484A (ja) * 1984-12-03 1991-03-27 Fujisawa Pharmaceut Co Ltd トリシクロ化合物
JPH03128320A (ja) * 1989-07-05 1991-05-31 Fujisawa Pharmaceut Co Ltd 水性外用液剤
JPH03209386A (ja) * 1989-11-13 1991-09-12 Merck & Co Inc 免疫抑制活性を有するアミノマクロライドおよび誘導体
JPH04503207A (ja) * 1988-11-21 1992-06-11 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー （アミノスルホニル）ピリジンカルボキシアミドの新規な水和物の製造方法
JPH04211012A (ja) * 1990-03-01 1992-08-03 Fujisawa Pharmaceut Co Ltd 溶液製剤
WO1993008802A1 (fr) * 1991-10-31 1993-05-13 Fujisawa Pharmaceutical Co., Ltd. Preparation de liposome contenant un compose tricyclique
JPH05155770A (ja) * 1990-11-08 1993-06-22 Fujisawa Pharmaceut Co Ltd 懸濁性組成物
JPH05247053A (ja) * 1991-05-13 1993-09-24 Merck & Co Inc 免疫抑制活性を有するｏ−アリール、ｏ−アルキル、ｏ−アルケニルおよびｏ−アルキニルマクロライド
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506
WO1994000430A1 (fr) * 1992-06-23 1994-01-06 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Delaminomycines, antibiotiques nouveaux presentant une activite immunosuppressive, et leur production
WO1994000438A1 (fr) * 1992-06-24 1994-01-06 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive de benzodiazepine
WO1994010981A1 (fr) * 1992-11-18 1994-05-26 Fujisawa Pharmaceutical Co., Ltd. Preparation pharmaceutique a action prolongee
WO1994028894A1 (fr) * 1993-06-08 1994-12-22 Fujisawa Pharmaceutical Co., Ltd. Lotion
WO1998046268A1 (fr) * 1997-04-11 1998-10-22 Fujisawa Pharmaceutical Co., Ltd. Composition medicamenteuse
JP2007527434A (ja) * 2005-01-05 2007-09-27 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 非晶質タクロリマス及びその調製
JP2007254483A (ja) * 2000-05-22 2007-10-04 Novartis Ag マクロライド類
WO2008026781A1 (en) 2006-08-31 2008-03-06 Astellas Pharma Inc. Reverse targeting lipid vesicle
JP2008518984A (ja) * 2004-11-03 2008-06-05 アンティビオーティコス エッセ．ピ．ア． タクロリムスの精製方法
JP2009502993A (ja) * 2005-08-05 2009-01-29 アンティビオーティコス エッセ．ピ．ア． 植物由来の担体上のタクロリムスの精製
WO2009054463A1 (ja) 2007-10-25 2009-04-30 Astellas Pharma Inc. 親油性ｉｌ－２産生抑制物質含有医薬組成物
WO2010041684A1 (ja) 2008-10-08 2010-04-15 高田製薬株式会社 タクロリムス外用剤

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2601869A1 (en) 2005-08-12 2007-02-22 Astellas Pharma Inc. Method for identifying target protein of agent and method for screening therapeutic agent for diabetes using target protein
EP2871188B1 (en) 2012-07-06 2017-04-19 Godo Shusei Co., Ltd. Method for separating cyclic macrolide compound

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0372484A (ja) * 1984-12-03 1991-03-27 Fujisawa Pharmaceut Co Ltd トリシクロ化合物
JPH0192659A (ja) * 1987-06-05 1989-04-11 Fujisawa Pharmaceut Co Ltd 抗ｆｒ−９００５０６物質抗体、および高感度酵素免疫測定法
JPH0219320A (ja) * 1988-01-07 1990-01-23 Merck & Co Inc 新規免疫抑制剤
JPH04503207A (ja) * 1988-11-21 1992-06-11 イー・アイ・デユポン・ドウ・ヌムール・アンド・カンパニー （アミノスルホニル）ピリジンカルボキシアミドの新規な水和物の製造方法
JPH03128320A (ja) * 1989-07-05 1991-05-31 Fujisawa Pharmaceut Co Ltd 水性外用液剤
JPH03209386A (ja) * 1989-11-13 1991-09-12 Merck & Co Inc 免疫抑制活性を有するアミノマクロライドおよび誘導体
JPH04211012A (ja) * 1990-03-01 1992-08-03 Fujisawa Pharmaceut Co Ltd 溶液製剤
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506
JPH05155770A (ja) * 1990-11-08 1993-06-22 Fujisawa Pharmaceut Co Ltd 懸濁性組成物
US5368865A (en) * 1990-11-08 1994-11-29 Fujisawa Pharmaceutical Co., Ltd. Suspendible composition and process for preparing the same
JPH05247053A (ja) * 1991-05-13 1993-09-24 Merck & Co Inc 免疫抑制活性を有するｏ−アリール、ｏ−アルキル、ｏ−アルケニルおよびｏ−アルキニルマクロライド
WO1993008802A1 (fr) * 1991-10-31 1993-05-13 Fujisawa Pharmaceutical Co., Ltd. Preparation de liposome contenant un compose tricyclique
WO1994000430A1 (fr) * 1992-06-23 1994-01-06 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Delaminomycines, antibiotiques nouveaux presentant une activite immunosuppressive, et leur production
WO1994000438A1 (fr) * 1992-06-24 1994-01-06 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive de benzodiazepine
WO1994010981A1 (fr) * 1992-11-18 1994-05-26 Fujisawa Pharmaceutical Co., Ltd. Preparation pharmaceutique a action prolongee
WO1994028894A1 (fr) * 1993-06-08 1994-12-22 Fujisawa Pharmaceutical Co., Ltd. Lotion
AU684286B2 (en) * 1993-06-08 1997-12-11 Astellas Pharma Inc. Lotion
WO1998046268A1 (fr) * 1997-04-11 1998-10-22 Fujisawa Pharmaceutical Co., Ltd. Composition medicamenteuse
JP2007254483A (ja) * 2000-05-22 2007-10-04 Novartis Ag マクロライド類
JP2008518984A (ja) * 2004-11-03 2008-06-05 アンティビオーティコス エッセ．ピ．ア． タクロリムスの精製方法
JP2007527434A (ja) * 2005-01-05 2007-09-27 テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ 非晶質タクロリマス及びその調製
JP2009502993A (ja) * 2005-08-05 2009-01-29 アンティビオーティコス エッセ．ピ．ア． 植物由来の担体上のタクロリムスの精製
WO2008026781A1 (en) 2006-08-31 2008-03-06 Astellas Pharma Inc. Reverse targeting lipid vesicle
EP2457589A1 (en) 2006-08-31 2012-05-30 Astellas Pharma Inc. Reverse targeting lipid vesicle
WO2009054463A1 (ja) 2007-10-25 2009-04-30 Astellas Pharma Inc. 親油性ｉｌ－２産生抑制物質含有医薬組成物
WO2010041684A1 (ja) 2008-10-08 2010-04-15 高田製薬株式会社 タクロリムス外用剤

Also Published As

Publication number Publication date
ZA858867B (en) 1986-09-24
GB8430455D0 (en) 1985-01-09
JPH0338276B2 (2) 1991-06-10

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