LU90230I2 - Cerivastatine (INN) et ses sels et dérivés pharmaceutiquement acceptables (LIPOBAY ) - Google Patents

Cerivastatine (INN) et ses sels et dérivés pharmaceutiquement acceptables (LIPOBAY )

Info

Publication number
LU90230I2
LU90230I2 LU90230C LU90230C LU90230I2 LU 90230 I2 LU90230 I2 LU 90230I2 LU 90230 C LU90230 C LU 90230C LU 90230 C LU90230 C LU 90230C LU 90230 I2 LU90230 I2 LU 90230I2
Authority
LU
Luxembourg
Prior art keywords
lipobay
cerivastatin
inn
derivatives
pharmaceutically acceptable
Prior art date
Application number
LU90230C
Other languages
English (en)
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4040026A external-priority patent/DE4040026A1/de
Priority claimed from IT002125A external-priority patent/ITMI912125A1/it
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of LU90230I2 publication Critical patent/LU90230I2/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/26—Radicals substituted by halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/56—Amides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Valve Device For Special Equipments (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
LU90230C 1990-12-14 1998-03-18 Cerivastatine (INN) et ses sels et dérivés pharmaceutiquement acceptables (LIPOBAY ) LU90230I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4040026A DE4040026A1 (de) 1990-12-14 1990-12-14 Substituierte pyridyl-dihydroxy-heptensaeure und deren salze
IT002125A ITMI912125A1 (it) 1991-07-31 1991-07-31 Acidi piridil-diidrossi-eptenoici sostituiti e loro sali

Publications (1)

Publication Number Publication Date
LU90230I2 true LU90230I2 (fr) 1998-05-18

Family

ID=25899340

Family Applications (1)

Application Number Title Priority Date Filing Date
LU90230C LU90230I2 (fr) 1990-12-14 1998-03-18 Cerivastatine (INN) et ses sels et dérivés pharmaceutiquement acceptables (LIPOBAY )

Country Status (25)

Country Link
US (1) US5177080A (fr)
EP (1) EP0491226B1 (fr)
JP (1) JP2786363B2 (fr)
KR (1) KR100192625B1 (fr)
CN (3) CN1034073C (fr)
AT (1) ATE141261T1 (fr)
AU (1) AU652977B2 (fr)
CA (1) CA2057444C (fr)
CZ (1) CZ282642B6 (fr)
DE (1) DE59108081D1 (fr)
DK (1) DK0491226T3 (fr)
ES (1) ES2091852T3 (fr)
FI (1) FI101069B (fr)
GR (1) GR3020826T3 (fr)
HU (2) HU221293B1 (fr)
IE (1) IE75691B1 (fr)
IL (1) IL100327A (fr)
LU (1) LU90230I2 (fr)
MY (1) MY107492A (fr)
NL (1) NL970033I1 (fr)
NO (2) NO177140C (fr)
NZ (1) NZ240946A (fr)
PL (1) PL169757B1 (fr)
PT (1) PT99776B (fr)
SK (1) SK280115B6 (fr)

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PT87929B (pt) * 1987-07-10 1995-03-01 Hoechst Ag Processo para a preparacao de derivados de acido 3-desmetil-mevalonico e de composicoes farmaceuticas que os contem
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HUT61282A (en) 1992-12-28
NO177140B (no) 1995-04-18
CN1329888A (zh) 2002-01-09
NO177140C (no) 1995-07-26
NO1998025I1 (no) 1998-10-22
CS360291A3 (en) 1992-06-17
FI915854A0 (fi) 1991-12-12
NO914696L (no) 1992-06-15
HU221293B1 (en) 2002-09-28
CN1034073C (zh) 1997-02-19
NZ240946A (en) 1993-09-27
NL970033I1 (nl) 1997-10-01
DK0491226T3 (da) 1997-01-06
PT99776A (pt) 1992-11-30
EP0491226A1 (fr) 1992-06-24
IL100327A (en) 1995-12-08
HU211695A9 (en) 1995-12-28
CA2057444C (fr) 1998-05-26
CA2057444A1 (fr) 1992-06-15
US5177080A (en) 1993-01-05
CN1062350A (zh) 1992-07-01
MY107492A (en) 1995-12-30
KR100192625B1 (en) 2002-02-19
PL169757B1 (pl) 1996-08-30
AU652977B2 (en) 1994-09-15
IE75691B1 (en) 1997-09-10
IE914350A1 (en) 1992-06-17
JP2786363B2 (ja) 1998-08-13
CZ282642B6 (cs) 1997-08-13
NO914696D0 (no) 1991-11-29
PT99776B (pt) 1999-05-31
PL292764A1 (en) 1992-08-24
CN1113485A (zh) 1995-12-20
ATE141261T1 (de) 1996-08-15
FI915854A7 (fi) 1992-06-15
DE59108081D1 (de) 1996-09-19
KR920012035A (ko) 1992-07-25
EP0491226B1 (fr) 1996-08-14
AU8961591A (en) 1992-06-18
JPH04308573A (ja) 1992-10-30
ES2091852T3 (es) 1996-11-16
HK1004552A1 (en) 1998-11-27
HU913945D0 (en) 1992-02-28
FI101069B (fi) 1998-04-15
SK280115B6 (sk) 1999-08-06
GR3020826T3 (en) 1996-11-30
CN1092641C (zh) 2002-10-16

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