MA27932A1 - Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derives - Google Patents
Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derivesInfo
- Publication number
- MA27932A1 MA27932A1 MA28753A MA28753A MA27932A1 MA 27932 A1 MA27932 A1 MA 27932A1 MA 28753 A MA28753 A MA 28753A MA 28753 A MA28753 A MA 28753A MA 27932 A1 MA27932 A1 MA 27932A1
- Authority
- MA
- Morocco
- Prior art keywords
- derivatives
- production
- thiazole
- dioxide
- substituted benzoisothiazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Abstract
L'invention concerne des composés de formule (I), dans laquelle les radicaux ont la signification indiquée dans la description, ainsi que leurs sels physiologiquement tolérables Ces composés sont appropriés par exemple comme médicaments servant à faire baisser le taux de sucre dans le sang et servant à la prévention et au traitement du diabète.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10334309A DE10334309A1 (de) | 2003-07-28 | 2003-07-28 | Substituierte Thiazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MA27932A1 true MA27932A1 (fr) | 2006-06-01 |
Family
ID=34111694
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MA28753A MA27932A1 (fr) | 2003-07-28 | 2006-01-26 | Derives du dioxyde de benzoisothiazole/thiazole substitues, procede de production et utilisation desdits derives |
Country Status (37)
| Country | Link |
|---|---|
| EP (1) | EP1651644B1 (fr) |
| JP (1) | JP2007500145A (fr) |
| KR (1) | KR20060052886A (fr) |
| CN (1) | CN100413862C (fr) |
| AR (1) | AR045113A1 (fr) |
| AT (1) | ATE346065T1 (fr) |
| AU (1) | AU2004261370B2 (fr) |
| BR (1) | BRPI0412997A (fr) |
| CA (1) | CA2533673A1 (fr) |
| CR (1) | CR8202A (fr) |
| CY (1) | CY1105962T1 (fr) |
| DE (2) | DE10334309A1 (fr) |
| DK (1) | DK1651644T3 (fr) |
| EC (1) | ECSP066326A (fr) |
| ES (1) | ES2276319T3 (fr) |
| GT (1) | GT200400146A (fr) |
| IL (1) | IL173289A0 (fr) |
| JO (1) | JO2449B1 (fr) |
| MA (1) | MA27932A1 (fr) |
| MY (1) | MY141197A (fr) |
| NO (1) | NO20060908L (fr) |
| NZ (1) | NZ544975A (fr) |
| OA (1) | OA13198A (fr) |
| PA (1) | PA8607201A1 (fr) |
| PE (1) | PE20050326A1 (fr) |
| PL (1) | PL1651644T3 (fr) |
| PT (1) | PT1651644E (fr) |
| RS (1) | RS20060015A (fr) |
| RU (1) | RU2350613C2 (fr) |
| SA (1) | SA04250332B1 (fr) |
| SI (1) | SI1651644T1 (fr) |
| TN (1) | TNSN06030A1 (fr) |
| TW (1) | TW200524923A (fr) |
| UA (1) | UA83057C2 (fr) |
| UY (1) | UY28443A1 (fr) |
| WO (1) | WO2005012295A1 (fr) |
| ZA (1) | ZA200510378B (fr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE102004026532A1 (de) * | 2004-05-29 | 2006-01-05 | Sanofi-Aventis Deutschland Gmbh | Substituierte Oxazol-Benzoisothiazoldioxidderivate, Verfahren zu deren Herstellung und deren Verwendung |
| EP2402317B1 (fr) | 2006-03-31 | 2013-07-03 | Novartis AG | Inhibiteur de la DGAT |
| BRPI0715160A2 (pt) | 2006-08-08 | 2013-06-11 | Sanofi Aventis | imidazolidina-2,4-dionas substituÍdas por arilamimoaril-alquil-, processo para preparÁ-las, medicamentos compeendendo estes compostos, e seu uso |
| EP2025674A1 (fr) | 2007-08-15 | 2009-02-18 | sanofi-aventis | Tetrahydronaphthaline substituée, son procédé de fabrication et son utilisation en tant que médicament |
| WO2010003624A2 (fr) | 2008-07-09 | 2010-01-14 | Sanofi-Aventis | Composés hétérocycliques, leurs procédés de préparation, médicaments comprenant lesdits composés et leur utilisation |
| WO2010068601A1 (fr) | 2008-12-08 | 2010-06-17 | Sanofi-Aventis | Hydrate de fluoroglycoside hétéroaromatique cristallin, ses procédés de fabrication, ses procédés d'utilisation et compositions pharmaceutiques le contenant |
| DK2470552T3 (en) | 2009-08-26 | 2014-02-17 | Sanofi Sa | NOVEL, CRYSTALLINE, heteroaromatic FLUORGLYCOSIDHYDRATER, MEDICINES COVERING THESE COMPOUNDS AND THEIR USE |
| WO2011107494A1 (fr) | 2010-03-03 | 2011-09-09 | Sanofi | Nouveaux dérivés aromatiques de glycoside, médicaments contenants ces composés, et leur utilisation |
| US8933024B2 (en) | 2010-06-18 | 2015-01-13 | Sanofi | Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases |
| US8530413B2 (en) | 2010-06-21 | 2013-09-10 | Sanofi | Heterocyclically substituted methoxyphenyl derivatives with an oxo group, processes for preparation thereof and use thereof as medicaments |
| TW201215387A (en) | 2010-07-05 | 2012-04-16 | Sanofi Aventis | Spirocyclically substituted 1,3-propane dioxide derivatives, processes for preparation thereof and use thereof as a medicament |
| TW201221505A (en) | 2010-07-05 | 2012-06-01 | Sanofi Sa | Aryloxyalkylene-substituted hydroxyphenylhexynoic acids, process for preparation thereof and use thereof as a medicament |
| TW201215388A (en) | 2010-07-05 | 2012-04-16 | Sanofi Sa | (2-aryloxyacetylamino)phenylpropionic acid derivatives, processes for preparation thereof and use thereof as medicaments |
| WO2012120054A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés oxathiazine di- et tri-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
| EP2683704B1 (fr) | 2011-03-08 | 2014-12-17 | Sanofi | Dérivés oxathiazine ramifiés, procédé pour leur préparation, utilisation en tant que médicament, agents pharmaceutiques contenant ces dérivés et leur utilisation |
| US8809325B2 (en) | 2011-03-08 | 2014-08-19 | Sanofi | Benzyl-oxathiazine derivatives substituted with adamantane and noradamantane, medicaments containing said compounds and use thereof |
| EP2683703B1 (fr) | 2011-03-08 | 2015-05-27 | Sanofi | Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, agent pharmaceutique contenant ces composés et leur utilisation |
| WO2012120056A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés oxathiazine tétra-substitués, procédé pour leur préparation, utilisation en tant que médicament, agent pharmaceutique contenant ces dérivés et utilisation |
| WO2012120058A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Dérivés d'oxathiazine substitués par des groupes benzyle ou hétérométhylène, leur procédé de production, leur utilisation comme médicament ainsi que produits pharmaceutiques les contenant et leur utilisation |
| WO2012120050A1 (fr) | 2011-03-08 | 2012-09-13 | Sanofi | Nouveaux dérivés phényl-oxathiazine substitués, procédé pour leur préparation, médicaments contenant ces composés et leur utilisation |
| US8710050B2 (en) | 2011-03-08 | 2014-04-29 | Sanofi | Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof |
| EP2766349B1 (fr) | 2011-03-08 | 2016-06-01 | Sanofi | Dérivés d'oxathiazine substitués par des carbocycles ou des hétérocycles, leur procédé de préparation, médicaments contenant ces composés et leur utilisation |
| WO2013037390A1 (fr) | 2011-09-12 | 2013-03-21 | Sanofi | Dérivés amides d'acide 6-(4-hydroxyphényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
| EP2567959B1 (fr) | 2011-09-12 | 2014-04-16 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxy-phényl)-3-styryl-1h-pyrazolo[3,4-b]pyridine-4-carboxylique en tant qu'inhibiteurs de kinase |
| WO2013045413A1 (fr) | 2011-09-27 | 2013-04-04 | Sanofi | Dérivés d'amide d'acide 6-(4-hydroxyphényl)-3-alkyl-1h-pyrazolo[3,4-b] pyridine-4-carboxylique utilisés comme inhibiteurs de kinase |
| AU2019318209B2 (en) | 2018-08-10 | 2025-09-25 | Diapin Therapeutics, Llc | Tri-peptides and treatment of metabolic, cardiovascular and inflammatory disorders |
| WO2025017207A1 (fr) * | 2023-07-20 | 2025-01-23 | Cemm - Forschungszentrum Für Molekulare Medizin Gmbh | Inhibiteurs de smndc1 et leur utilisation thérapeutique |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3539584A (en) * | 1967-11-14 | 1970-11-10 | Colgate Palmolive Co | 5-substituted-2,1-benzisothiazolines |
| JPH04128276A (ja) * | 1990-09-19 | 1992-04-28 | Pfizer Pharmaceut Co Ltd | アミノベンゾサルタム誘導体およびその用途 |
| ATE184005T1 (de) * | 1995-06-02 | 1999-09-15 | Synthelabo | Oxazolidinone derivate, ihre herstellung und ihre therapeutische verwendung |
| CO5190696A1 (es) * | 1999-06-16 | 2002-08-29 | Smithkline Beecham Corp | Antagonistas de los receptores il-8 |
| DE10038709A1 (de) * | 2000-08-09 | 2002-02-28 | Aventis Pharma Gmbh | Substituierte und unsubstituierte Benzooxathiazole sowie daraus abgeleitete Verbindungen |
-
2003
- 2003-07-28 DE DE10334309A patent/DE10334309A1/de not_active Withdrawn
-
2004
- 2004-06-14 JO JO200481A patent/JO2449B1/en active
- 2004-07-13 PE PE2004000664A patent/PE20050326A1/es not_active Application Discontinuation
- 2004-07-15 RU RU2006106231/04A patent/RU2350613C2/ru not_active IP Right Cessation
- 2004-07-15 RS YUP-2006/0015A patent/RS20060015A/sr unknown
- 2004-07-15 PA PA20048607201A patent/PA8607201A1/es unknown
- 2004-07-15 SI SI200430126T patent/SI1651644T1/sl unknown
- 2004-07-15 JP JP2006521446A patent/JP2007500145A/ja not_active Abandoned
- 2004-07-15 AT AT04741034T patent/ATE346065T1/de not_active IP Right Cessation
- 2004-07-15 WO PCT/EP2004/007847 patent/WO2005012295A1/fr not_active Ceased
- 2004-07-15 PT PT04741034T patent/PT1651644E/pt unknown
- 2004-07-15 DK DK04741034T patent/DK1651644T3/da active
- 2004-07-15 KR KR1020067001721A patent/KR20060052886A/ko not_active Ceased
- 2004-07-15 CA CA002533673A patent/CA2533673A1/fr not_active Abandoned
- 2004-07-15 PL PL04741034T patent/PL1651644T3/pl unknown
- 2004-07-15 BR BRPI0412997-0A patent/BRPI0412997A/pt not_active IP Right Cessation
- 2004-07-15 NZ NZ544975A patent/NZ544975A/en unknown
- 2004-07-15 ES ES04741034T patent/ES2276319T3/es not_active Expired - Lifetime
- 2004-07-15 CN CNB2004800220877A patent/CN100413862C/zh not_active Expired - Fee Related
- 2004-07-15 UA UAA200602134A patent/UA83057C2/ru unknown
- 2004-07-15 AU AU2004261370A patent/AU2004261370B2/en not_active Ceased
- 2004-07-15 EP EP04741034A patent/EP1651644B1/fr not_active Expired - Lifetime
- 2004-07-15 OA OA1200600026A patent/OA13198A/en unknown
- 2004-07-15 DE DE502004002117T patent/DE502004002117D1/de not_active Expired - Lifetime
- 2004-07-23 GT GT200400146A patent/GT200400146A/es unknown
- 2004-07-26 AR ARP040102644A patent/AR045113A1/es not_active Application Discontinuation
- 2004-07-26 TW TW093122232A patent/TW200524923A/zh unknown
- 2004-07-27 MY MYPI20043005A patent/MY141197A/en unknown
- 2004-07-28 UY UY28443A patent/UY28443A1/es unknown
- 2004-10-11 SA SA04250332A patent/SA04250332B1/ar unknown
-
2005
- 2005-12-21 ZA ZA200510378A patent/ZA200510378B/xx unknown
-
2006
- 2006-01-18 CR CR8202A patent/CR8202A/es not_active Application Discontinuation
- 2006-01-22 IL IL173289A patent/IL173289A0/en unknown
- 2006-01-26 EC EC2006006326A patent/ECSP066326A/es unknown
- 2006-01-26 MA MA28753A patent/MA27932A1/fr unknown
- 2006-01-27 TN TNP2006000030A patent/TNSN06030A1/en unknown
- 2006-02-24 NO NO20060908A patent/NO20060908L/no not_active Application Discontinuation
-
2007
- 2007-01-29 CY CY20071100112T patent/CY1105962T1/el unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| MA31979B1 (fr) | (cyclopropylphenyl) phenyloxamides, leur procede de production et leur utilisation comme medicament | |
| MXPA03011083A (es) | Compuestos de sulfonamida sustituida, procedimiento para su preparacion, y su uso como medicamento para el tratamiento de trastornos del sistema nervioso central. obesidad y diabetes tipo ii. | |
| MA27134A1 (fr) | Derives diarylcycloalkyle, leur procede de preparation et leur utilisation en tant qu'activateurs des ppar | |
| TNSN07022A1 (fr) | Derives de pyridine | |
| NO20055680L (no) | Heksahydropyridoisokinoliner som DPP-IV-inhibitorer | |
| MA31710B1 (fr) | (carboxylalkylenephenyl)phényloxamides, procédés pour la production de ceux-ci et utilisation de ceux-ci en tant que medicament | |
| MA29685B1 (fr) | Composes spiroheterocycliques et leurs utilisations en tant qu'agents therapeutiques | |
| MA27559A1 (fr) | Nouveaux derives de fluorglycoside aromatiques, produits pharmaceutiques contenant ces composes et leur utilisation | |
| MA27654A1 (fr) | DERIVES HEXAHYDROPYRAZINO [1,2-a]-4,7-DIONE SUBSTITUES, METHODE POUR LEUR PRODUCTION ET LEUR UTILISATION EN TANT QUE MEDICAMENTS | |
| MA31894B1 (fr) | Composes organiques | |
| JO2449B1 (en) | Thiosol derivatives - benziazothiazole dioxide, methods of preparation and use. | |
| TNSN04211A1 (fr) | Phenylacetamides substitues et leurs utilisation en tant qu'activateurs de la glucokinase | |
| MA27734A1 (fr) | DERIVES HEXAHYDROPYRAZINO [1,2-a]PYRIMIDINE-4,7-DIONE SUBSTITUES SUR L'AZOTE, METHODE POUR LEUR PRODUCTION ET LEUR UTILISATION EN TANT QUE MEDICAMENTS | |
| MA30911B1 (fr) | Nouveaux derives de sulfonamide en tant qu'antagonistes de bradykinine | |
| MA27097A1 (fr) | Aza-arylpiperazines | |
| MA30402B1 (fr) | Acides carboxyliques substitues par des phenylamino-benzoxazoles, leur procede de production et leur utilisation comme medicaments | |
| MA29926B1 (fr) | Derives de pyrazine | |
| MA30089B1 (fr) | (arylsulfonyl)-pyrasolopiperidines | |
| NO20055649L (no) | Substituert dihydrokinazolin med antiviale egenskaper | |
| SE0403006D0 (sv) | New compounds | |
| MA30609B1 (fr) | Imidazolidine-2,4-diones arylaminoaryl-alkyl-substituees, leur procede de synthese, les medicaments comprenant ces composes, et leurs applications. | |
| MA27093A1 (fr) | Derives de sulfonamides, leur preparation et leur application comme medicaments. | |
| MA30405B1 (fr) | Derives de 4-benzylphtalazinone substitues en 2 en tant qu'antagonistes des histamines hl et h3 | |
| MA27751A1 (fr) | 4-phényltétrahydroisoquinolines substituées, procédé de production de ces composés, utilisation de ces composés en tant que médicaments et médicament contenant de tels composés | |
| IS8485A (is) | Notkun á setnum 2-amínótetralínum í fyrirbyggjandi meðferð á Parkinsons-veiki |