MA29399B1 - Nouveaux ligands du recepteur h3 de l'histamine et leurs applications therapeutiques - Google Patents

Nouveaux ligands du recepteur h3 de l'histamine et leurs applications therapeutiques

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Publication number
MA29399B1
MA29399B1 MA30309A MA30309A MA29399B1 MA 29399 B1 MA29399 B1 MA 29399B1 MA 30309 A MA30309 A MA 30309A MA 30309 A MA30309 A MA 30309A MA 29399 B1 MA29399 B1 MA 29399B1
Authority
MA
Morocco
Prior art keywords
therapeutic applications
receptor ligands
novel histamine
novel
histamine
Prior art date
Application number
MA30309A
Other languages
English (en)
Inventor
Isabelle Bertrand
Marc Capet
Jeanne-Marie Lecomte
Nicolas Levoin
Xavier Ligneau
Olivia Poupardin-Olivier
Philippe Robert
Jean-Charles Schwartz
Olivier Labeeuw
Original Assignee
Bioprojet Soc Civ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP05290950A external-priority patent/EP1717234A1/fr
Application filed by Bioprojet Soc Civ filed Critical Bioprojet Soc Civ
Publication of MA29399B1 publication Critical patent/MA29399B1/fr

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    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
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    • C07D207/20—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Psychology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

LA PRÉSENTE INVENTION SE RAPPORTE À DE NOUVEAUX COMPOSÉS REPRÉSENTÉS PAR LA FORMULE (I), À LEUR PROCÉDÉ DE PRÉPARATION ET À LEUR UTILISATION THÉRAPEUTIQUE.
MA30309A 2005-04-29 2007-10-23 Nouveaux ligands du recepteur h3 de l'histamine et leurs applications therapeutiques MA29399B1 (fr)

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EP05290950A EP1717234A1 (fr) 2005-04-29 2005-04-29 Phenoxypropylpiperidines and -pyrrolidines et leur utilisation comme ligands du récepteur histaminique H3
US67824305P 2005-05-06 2005-05-06
EP05291793A EP1717235A3 (fr) 2005-04-29 2005-08-26 Phenoxypropylpiperidines and -pyrrolidines et leur utilisation comme ligands du récepteur histaminique H3

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AU (1) AU2006242950B2 (fr)
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CA (1) CA2606262C (fr)
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HU (1) HUE026549T2 (fr)
MA (1) MA29399B1 (fr)
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NZ (1) NZ562873A (fr)
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WO2006117609A3 (fr) 2007-03-22
NO20075624L (no) 2007-11-28
NO340728B1 (no) 2017-06-06
EP1717235A3 (fr) 2007-02-28
NZ562873A (en) 2011-03-31
SI1874746T1 (sl) 2016-03-31
EP1874746B1 (fr) 2015-11-18
CN101258138A (zh) 2008-09-03
HUE026549T2 (hu) 2016-06-28
EA019594B1 (ru) 2014-04-30
KR20080005997A (ko) 2008-01-15
CA2606262C (fr) 2013-08-20
TNSN07393A1 (fr) 2009-03-17
DK1874746T3 (en) 2016-02-15
AU2006242950B2 (en) 2013-01-10
BRPI0612957B8 (pt) 2021-05-25
US8076329B2 (en) 2011-12-13
CN101258138B (zh) 2013-06-12
JP5693814B2 (ja) 2015-04-01
EP1717235A2 (fr) 2006-11-02
JP2008539218A (ja) 2008-11-13
US20090111808A1 (en) 2009-04-30
SG162732A1 (en) 2010-07-29
WO2006117609A2 (fr) 2006-11-09
BRPI0612957B1 (pt) 2020-10-27
CA2606262A1 (fr) 2006-11-09
EP1874746A2 (fr) 2008-01-09
EA200702363A1 (ru) 2008-04-28
ES2563065T3 (es) 2016-03-10
PT1874746E (pt) 2016-03-22
AU2006242950A1 (en) 2006-11-09
KR101291575B1 (ko) 2013-08-08
PL1874746T3 (pl) 2016-06-30
MX2007013384A (es) 2008-01-21
BRPI0612957A2 (pt) 2010-12-07

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