MA30671B1 - Vaccins contre le paludisme - Google Patents

Vaccins contre le paludisme

Info

Publication number
MA30671B1
MA30671B1 MA31672A MA31672A MA30671B1 MA 30671 B1 MA30671 B1 MA 30671B1 MA 31672 A MA31672 A MA 31672A MA 31672 A MA31672 A MA 31672A MA 30671 B1 MA30671 B1 MA 30671B1
Authority
MA
Morocco
Prior art keywords
protein
particle
hepatitis
antigen
vaccines against
Prior art date
Application number
MA31672A
Other languages
English (en)
Inventor
Joseph D Cohen
Martine Marchand
Christian F Ockenhouse
Anjali Yadava
Original Assignee
Glaxosmithkline Biolog Sa
Us Army
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB0614254.1A external-priority patent/GB0614254D0/en
Priority claimed from GB0614476A external-priority patent/GB0614476D0/en
Priority claimed from GB0614473A external-priority patent/GB0614473D0/en
Priority claimed from GB0615115A external-priority patent/GB0615115D0/en
Application filed by Glaxosmithkline Biolog Sa, Us Army filed Critical Glaxosmithkline Biolog Sa
Publication of MA30671B1 publication Critical patent/MA30671B1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/29—Hepatitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6075—Viral proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne une particule lipoprotéique innovante, des procédés de préparation et de purification de celle-ci, son utilisation en médecine, en particulier pour la prévention des infections paludéennes, des compositions/vaccins contenant la particule ou des anticorps contre la particule protéique tels que des anticorps monoclonaux ou polyclonaux et leur utilisation, en particulier dans des buts thérapeutiques. L'invention concerne en particulier une particule protéique immunogène qui comprend les monomères suivants: (a) une protéine de fusion comprenant des séquences dérivées d'une protéine CS de P. vivax et de l'antigène S de l'hépatite B (CSV-S), et (b) une protéine de fusion comprenant des séquences dérivées d'une protéine CS de P. falciparum et de l'antigène S de l'hépatite B (RTS), et (c) facultativement l'antigène S dérivé de l'hépatite B.
MA31672A 2006-07-18 2009-02-27 Vaccins contre le paludisme MA30671B1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GBGB0614254.1A GB0614254D0 (en) 2006-07-18 2006-07-18 Vaccine
GB0614476A GB0614476D0 (en) 2006-07-20 2006-07-20 Vaccine
GB0614473A GB0614473D0 (en) 2006-07-20 2006-07-20 Vaccines
GB0615115A GB0615115D0 (en) 2006-07-28 2006-07-28 Vaccines

Publications (1)

Publication Number Publication Date
MA30671B1 true MA30671B1 (fr) 2009-08-03

Family

ID=38957130

Family Applications (2)

Application Number Title Priority Date Filing Date
MA31672A MA30671B1 (fr) 2006-07-18 2009-02-27 Vaccins contre le paludisme
MA31671A MA30670B1 (fr) 2006-07-18 2009-02-27 Vaccins contre le paludisme

Family Applications After (1)

Application Number Title Priority Date Filing Date
MA31671A MA30670B1 (fr) 2006-07-18 2009-02-27 Vaccins contre le paludisme

Country Status (22)

Country Link
US (2) US9592282B2 (fr)
EP (2) EP2040742B1 (fr)
JP (2) JP5222289B2 (fr)
KR (2) KR20090092752A (fr)
AR (1) AR061894A1 (fr)
AU (2) AU2007276217B2 (fr)
BR (2) BRPI0714326A2 (fr)
CA (2) CA2657279A1 (fr)
CO (2) CO6150187A2 (fr)
CR (2) CR10555A (fr)
EA (2) EA200900033A1 (fr)
ES (2) ES2437082T3 (fr)
IL (2) IL196410A0 (fr)
MA (2) MA30671B1 (fr)
MX (2) MX2009000655A (fr)
NO (2) NO20090178L (fr)
NZ (2) NZ574238A (fr)
PE (1) PE20080428A1 (fr)
SG (2) SG173377A1 (fr)
TW (1) TW200819462A (fr)
WO (2) WO2008009652A2 (fr)
ZA (1) ZA200900386B (fr)

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MXPA04004876A (es) 2001-11-21 2004-07-30 Univ Pennsylvania Secuencias de acido nucleico y de aminoacido de adenovirus de simio, vectores que contienen los mismos y metodos de uso.
JP5222289B2 (ja) * 2006-07-18 2013-06-26 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム マラリア用ワクチン
CA2707245A1 (fr) * 2007-12-06 2009-06-11 Glaxosmithkline Biologicals S.A. Vaccin
AP2010005294A0 (en) 2007-12-24 2010-06-30 Glaxosmithkline Biolog Sa Vaccines for malaria
WO2010036293A1 (fr) * 2008-09-24 2010-04-01 The Johns Hokins University Vaccin contre le paludisme
EA019928B1 (ru) 2008-11-03 2014-07-30 Круселл Холланд Б.В. Способ получения аденовирусных векторов
US8784832B2 (en) 2011-08-19 2014-07-22 University Of South Florida (A Florida Non-Profit Corporation) Synthetic antigen based on the ligand domain of the Plasmodium vivax duffy binding protein
GB201116248D0 (en) 2011-09-20 2011-11-02 Glaxosmithkline Biolog Sa Liposome production using isopropanol
US9580482B2 (en) 2012-02-17 2017-02-28 Children's Medical Center Corporation Conformation-stabilized TRAP antigens
WO2014111733A1 (fr) * 2013-01-21 2014-07-24 Isis Innovation Limited Composition et ses applications
EP3213638A1 (fr) 2016-03-01 2017-09-06 Coöperatie Avebe U.A. Analogue de fromage vegan
GB201608821D0 (en) 2016-05-19 2016-07-06 Isis Innovation Vaccines
CA3045952A1 (fr) 2016-12-07 2018-06-14 Glaxosmithkline Biologicals Sa Nouveau procede
BR112019012843A2 (pt) * 2016-12-23 2019-12-17 The Walter And Eliza Hall Institute Of Medical Research teste de diagnóstico, e, aparelho, sistema e método para o diagnóstico de p. vivax ou p. ovale.

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Also Published As

Publication number Publication date
CO6150189A2 (es) 2010-04-20
CA2657353A1 (fr) 2008-01-24
NZ574238A (en) 2012-02-24
PE20080428A1 (es) 2008-05-15
AU2007276219A1 (en) 2008-01-24
US9364525B2 (en) 2016-06-14
WO2008009650A2 (fr) 2008-01-24
BRPI0715581A2 (pt) 2013-04-24
EP2040743A2 (fr) 2009-04-01
CA2657279A1 (fr) 2008-01-24
EP2040742B1 (fr) 2014-10-29
MA30670B1 (fr) 2009-08-03
ES2437082T3 (es) 2014-01-08
AU2007276217A1 (en) 2008-01-24
JP2009543846A (ja) 2009-12-10
IL196471A0 (en) 2011-08-01
JP2009543569A (ja) 2009-12-10
NO20090178L (no) 2009-02-09
MX2009000655A (es) 2009-07-02
TW200819462A (en) 2008-05-01
MX2009000650A (es) 2009-07-02
NZ574239A (en) 2011-12-22
BRPI0714326A2 (pt) 2013-05-07
SG173363A1 (en) 2011-08-29
JP5222289B2 (ja) 2013-06-26
US9592282B2 (en) 2017-03-14
CR10561A (es) 2009-04-29
WO2008009652A3 (fr) 2008-05-08
IL196410A0 (en) 2011-08-01
KR20090094213A (ko) 2009-09-04
ZA200900386B (en) 2014-03-26
AU2007276219B2 (en) 2013-10-03
AU2007276217B2 (en) 2013-08-29
WO2008009650A3 (fr) 2008-04-10
US20100062028A1 (en) 2010-03-11
KR20090092752A (ko) 2009-09-01
CO6150187A2 (es) 2010-04-20
EP2040743B1 (fr) 2013-10-02
EA200900033A1 (ru) 2009-12-30
US20100150998A1 (en) 2010-06-17
NO20090177L (no) 2009-02-16
AR061894A1 (es) 2008-10-01
ES2525732T3 (es) 2014-12-29
WO2008009652A2 (fr) 2008-01-24
AU2007276217A8 (en) 2009-02-26
CR10555A (es) 2009-04-29
EP2040742A2 (fr) 2009-04-01
SG173377A1 (en) 2011-08-29
JP5592110B2 (ja) 2014-09-17
EA200900032A1 (ru) 2011-02-28

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