MC1984A1 - Derives de la purine - Google Patents

Derives de la purine

Info

Publication number
MC1984A1
MC1984A1 MC882013A MC2013A MC1984A1 MC 1984 A1 MC1984 A1 MC 1984A1 MC 882013 A MC882013 A MC 882013A MC 2013 A MC2013 A MC 2013A MC 1984 A1 MC1984 A1 MC 1984A1
Authority
MC
Monaco
Prior art keywords
purine
amino
trityl
fluoro
dideoxy
Prior art date
Application number
MC882013A
Other languages
English (en)
French (fr)
Inventor
Wilson Lambert Robert
Armstrong Martin Joseph
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878725466A external-priority patent/GB8725466D0/en
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of MC1984A1 publication Critical patent/MC1984A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
MC882013A 1987-10-30 1988-10-27 Derives de la purine MC1984A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878725466A GB8725466D0 (en) 1987-10-30 1987-10-30 Purine derivatives
GB888816612A GB8816612D0 (en) 1987-10-30 1988-06-13 Purine derivatives

Publications (1)

Publication Number Publication Date
MC1984A1 true MC1984A1 (fr) 1989-11-23

Family

ID=26292971

Family Applications (1)

Application Number Title Priority Date Filing Date
MC882013A MC1984A1 (fr) 1987-10-30 1988-10-27 Derives de la purine

Country Status (15)

Country Link
EP (1) EP0314011A3 (da)
JP (1) JPH01149797A (da)
CN (1) CN1038102A (da)
AU (1) AU2416088A (da)
CS (1) CS270249B2 (da)
DK (1) DK603788A (da)
FI (1) FI884954A7 (da)
HU (1) HU199502B (da)
IL (1) IL88138A0 (da)
MC (1) MC1984A1 (da)
NO (1) NO168037C (da)
NZ (1) NZ226672A (da)
PH (1) PH25577A (da)
PT (1) PT88891B (da)
YU (1) YU199688A (da)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5310732A (en) * 1986-02-03 1994-05-10 The Scripps Research Institute 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis
US5106837A (en) * 1988-03-16 1992-04-21 The Scripps Research Institute Adenosine derivatives with therapeutic activity
US4908440A (en) * 1987-11-12 1990-03-13 Bristol Myers Company 2',3'-dideoxy-2'-fluoroarabinopyrimidine nucleosides
US4997926A (en) * 1987-11-18 1991-03-05 Scripps Clinic And Research Foundation Deaminase-stable anti-retroviral 2-halo-2',3'-dideoxy
WO1989008658A1 (en) * 1988-03-16 1989-09-21 Scripps Clinic And Research Foundation Substituted adenine derivatives useful as therapeutic agents
NZ232912A (en) * 1989-03-17 1992-06-25 Oncogen Ltd Lp Synergistic composition of nucleoside derivatives for inhibiting hiv
US5034518A (en) * 1989-05-23 1991-07-23 Southern Research Institute 2-fluoro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl) adenine nucleosides
US5384310A (en) * 1989-05-23 1995-01-24 Southern Research Institute 2'-fluoro-2-haloarabinoadinosines and their pharmaceutical compositions
HU906976D0 (en) * 1989-11-13 1991-05-28 Bristol Myers Squibb Co Process for producing 2', 3'-didesoxy-2'-fluoarabinonucleoside analogues
AU3851601A (en) * 2000-02-18 2001-08-27 Southern Res Inst Methods for synthesizing 2-chloro-9-(2-deoxy-2-fluoro-beta-d-arabinofuranosyl)-9h- purin-6-amine
US6753322B2 (en) 2000-06-06 2004-06-22 Pfizer Inc 2-aminocarbonyl-9H-purine derivatives
US7528247B2 (en) 2001-08-02 2009-05-05 Genzyme Corporation Process for preparing purine nucleosides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340645C (en) * 1987-04-17 1999-07-13 Victor E. Marquez Acid stable dideoxynucleosides active against the cytopathic effects of human immunodeficiency virus

Also Published As

Publication number Publication date
NO884830L (no) 1989-05-02
HU199502B (en) 1990-02-28
FI884954A7 (fi) 1989-05-01
NZ226672A (en) 1991-07-26
NO884830D0 (no) 1988-10-28
NO168037B (no) 1991-09-30
EP0314011A3 (de) 1990-04-11
IL88138A0 (en) 1989-06-30
FI884954A0 (fi) 1988-10-27
CN1038102A (zh) 1989-12-20
YU199688A (en) 1990-04-30
NO168037C (no) 1992-01-08
CS705788A2 (en) 1989-10-13
HUT48270A (en) 1989-05-29
JPH01149797A (ja) 1989-06-12
DK603788A (da) 1989-05-01
DK603788D0 (da) 1988-10-28
CS270249B2 (en) 1990-06-13
PT88891B (pt) 1993-01-29
EP0314011A2 (de) 1989-05-03
PH25577A (en) 1991-08-08
AU2416088A (en) 1989-05-04

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