NO155290C - Analogifremgangsmaate til fremstilling av terapeutisk virksomme sulfonylurinstoffderivater. - Google Patents

Analogifremgangsmaate til fremstilling av terapeutisk virksomme sulfonylurinstoffderivater.

Info

Publication number
NO155290C
NO155290C NO803855A NO803855A NO155290C NO 155290 C NO155290 C NO 155290C NO 803855 A NO803855 A NO 803855A NO 803855 A NO803855 A NO 803855A NO 155290 C NO155290 C NO 155290C
Authority
NO
Norway
Prior art keywords
sulphonylurine
ingredients
preparation
therapeutically effective
analogue procedure
Prior art date
Application number
NO803855A
Other languages
English (en)
Norwegian (no)
Other versions
NO155290B (no
NO803855L (no
Inventor
Rudi Weyer
Volker Hitzel
Karl Geisen
Guenter Regitz
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO803855L publication Critical patent/NO803855L/no
Publication of NO155290B publication Critical patent/NO155290B/no
Publication of NO155290C publication Critical patent/NO155290C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/27—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36—Oxygen or sulfur atoms
    • C07D207/38—2-Pyrrolones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D211/74—Oxygen atoms
    • C07D211/76—Oxygen atoms attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D223/08—Oxygen atoms
    • C07D223/10—Oxygen atoms attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO803855A 1979-12-19 1980-12-18 Analogifremgangsmaate til fremstilling av terapeutisk virksomme sulfonylurinstoffderivater. NO155290C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792951135 DE2951135A1 (de) 1979-12-19 1979-12-19 Sulfonylharnstoffe, verfahren zu ihrer herstellung, pharmazeutische praeparate auf basis dieser verbindungen und ihre verwendung

Publications (3)

Publication Number Publication Date
NO803855L NO803855L (no) 1981-06-22
NO155290B NO155290B (no) 1986-12-01
NO155290C true NO155290C (no) 1987-03-11

Family

ID=6088937

Family Applications (2)

Application Number Title Priority Date Filing Date
NO803855A NO155290C (no) 1979-12-19 1980-12-18 Analogifremgangsmaate til fremstilling av terapeutisk virksomme sulfonylurinstoffderivater.
NO1996009C NO1996009I1 (no) 1979-12-19 1996-07-30 Glimepiride

Family Applications After (1)

Application Number Title Priority Date Filing Date
NO1996009C NO1996009I1 (no) 1979-12-19 1996-07-30 Glimepiride

Country Status (21)

Country Link
US (1) US4379785A (fr)
EP (1) EP0031058B1 (fr)
JP (1) JPS56108762A (fr)
AR (3) AR240922A1 (fr)
AT (1) ATE6934T1 (fr)
AU (1) AU538129B2 (fr)
CA (1) CA1167033A (fr)
DE (2) DE2951135A1 (fr)
DK (1) DK156434C (fr)
ES (6) ES8200665A1 (fr)
FI (1) FI75338C (fr)
GR (1) GR72534B (fr)
HU (1) HU184943B (fr)
IE (1) IE50635B1 (fr)
IL (1) IL61733A (fr)
LU (1) LU90244I2 (fr)
MX (4) MX174496B (fr)
NL (1) NL950026I2 (fr)
NO (2) NO155290C (fr)
PT (1) PT72226B (fr)
ZA (1) ZA807911B (fr)

Families Citing this family (111)

* Cited by examiner, † Cited by third party
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US4985417A (en) * 1989-05-02 1991-01-15 Trager Seymour F Treatment of glaucoma
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DE4344957A1 (de) * 1993-12-30 1995-07-06 Hoechst Ag Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Herstellungsverfahren und Verwendungsmöglichkeiten pharmazeutischer Präparate auf Basis dieser Verbindungen
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DK540280A (da) 1981-06-20
IE50635B1 (en) 1986-05-28
HU184943B (en) 1984-11-28
NO155290B (no) 1986-12-01
FI75338B (fi) 1988-02-29
JPH0139424B2 (fr) 1989-08-21
ES498227A0 (es) 1982-02-01
EP0031058A1 (fr) 1981-07-01
NL950026I1 (fr) 1996-01-02
MX8352A (es) 1993-11-01
IL61733A (en) 1985-05-31
ES497661A0 (es) 1981-11-01
JPS56108762A (en) 1981-08-28
AR231131A1 (es) 1984-09-28
DE2951135A1 (de) 1981-06-25
PT72226B (de) 1982-03-26
AU538129B2 (en) 1984-08-02
ES498224A0 (es) 1982-02-01
MX174496B (es) 1994-05-19
AR240922A1 (es) 1991-03-27
AU6552380A (en) 1981-06-25
IE802676L (en) 1981-06-19
ZA807911B (en) 1981-12-30
FI803937L (fi) 1981-06-20
ES8202542A1 (es) 1982-02-01
ES8200665A1 (es) 1981-11-01
ES8202798A1 (es) 1982-03-01
LU90244I2 (fr) 1998-07-20
ES8202543A1 (es) 1982-02-01
ES498228A0 (es) 1982-02-01
ES8202799A1 (es) 1982-03-01
EP0031058B1 (fr) 1984-04-04
DK156434B (da) 1989-08-21
AR240922A2 (es) 1991-03-27
NO803855L (no) 1981-06-22
ES498225A0 (es) 1982-03-01
DK156434C (da) 1990-01-22
PT72226A (de) 1981-01-01
IL61733A0 (en) 1981-01-30
ES498226A0 (es) 1982-03-01
ES8202541A1 (es) 1982-02-01
DE3067390D1 (en) 1984-05-10
MX8254A (es) 1993-04-01
AR230989A1 (es) 1984-08-31
GR72534B (fr) 1983-11-17
NO1996009I1 (no) 1996-07-30
US4379785A (en) 1983-04-12
ATE6934T1 (de) 1984-04-15
MX6926E (es) 1986-12-01
NL950026I2 (nl) 1997-01-06
FI75338C (fi) 1988-06-09
CA1167033A (fr) 1984-05-08

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