NO913232L - Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse. - Google Patents

Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse.

Info

Publication number
NO913232L
NO913232L NO91913232A NO913232A NO913232L NO 913232 L NO913232 L NO 913232L NO 91913232 A NO91913232 A NO 91913232A NO 913232 A NO913232 A NO 913232A NO 913232 L NO913232 L NO 913232L
Authority
NO
Norway
Prior art keywords
analogs
production
growth factor
derived growth
pdgf
Prior art date
Application number
NO91913232A
Other languages
English (en)
Norwegian (no)
Other versions
NO913232D0 (no
Inventor
Arlen Read Thomason
Original Assignee
Amgen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/454,794 external-priority patent/US5149792A/en
Application filed by Amgen Inc filed Critical Amgen Inc
Publication of NO913232D0 publication Critical patent/NO913232D0/no
Publication of NO913232L publication Critical patent/NO913232L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475Growth factors; Growth regulators
    • C07K14/49Platelet-derived growth factor [PDGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
NO91913232A 1989-12-19 1991-08-19 Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse. NO913232L (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US07/454,794 US5149792A (en) 1989-12-19 1989-12-19 Platelet-derived growth factor B chain analogs
US07/624,451 US5272064A (en) 1989-12-19 1990-12-13 DNA molecules encoding platelet-derived growth factor B chain analogs and method for expression thereof
PCT/US1990/007451 WO1991008761A1 (en) 1989-12-19 1990-12-17 Novel platelet-derived growth factor b chain analogs and method for homogeneous production thereof

Publications (2)

Publication Number Publication Date
NO913232D0 NO913232D0 (no) 1991-08-19
NO913232L true NO913232L (no) 1991-08-19

Family

ID=27037609

Family Applications (1)

Application Number Title Priority Date Filing Date
NO91913232A NO913232L (no) 1989-12-19 1991-08-19 Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse.

Country Status (17)

Country Link
US (1) US5272064A (de)
EP (1) EP0458959B1 (de)
JP (1) JPH04504064A (de)
AT (1) ATE123949T1 (de)
AU (1) AU646014B2 (de)
CA (1) CA2032675A1 (de)
DE (1) DE69020335T2 (de)
DK (1) DK0458959T3 (de)
ES (1) ES2073735T3 (de)
FI (1) FI913892A7 (de)
GR (1) GR3017317T3 (de)
IE (1) IE904608A1 (de)
IL (1) IL96723A0 (de)
NO (1) NO913232L (de)
NZ (1) NZ236549A (de)
PT (1) PT96272A (de)
WO (1) WO1991008761A1 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07507055A (ja) * 1992-02-26 1995-08-03 アラーガン、インコーポレイテッド 眼の創傷の治癒における血小板誘導化成長因子の使用
IL105176A0 (en) * 1992-03-30 1993-07-08 Schering Corp Monomeric platelet-derived growth factor and prevention of stenosis or restenosis
CA2480121C (en) 2002-03-27 2012-02-28 Immunex Corporation Methods for increasing polypeptide production
US20040248796A1 (en) * 2003-02-04 2004-12-09 Kari Alitalo VEGF-B and PDGF modulation of stem cells
WO2011008904A1 (en) 2009-07-17 2011-01-20 Tabor Aaron T Compositions and methods for genetic modification of cells having cosmetic function to enhance cosmetic appearance
SG187198A1 (en) 2010-08-05 2013-03-28 Amgen Inc Dipeptides to enhance yield and viability from cell cultures
HUE042822T2 (hu) 2011-04-20 2019-07-29 Amgen Inc Automata befecskendezõ szerkezet
WO2012145682A1 (en) 2011-04-21 2012-10-26 Amgen Inc. A method for culturing mammalian cells to improve recombinant protein production
PT2837680T (pt) 2011-07-01 2020-04-17 Amgen Inc Cultura celular de mamífero
JP2014529473A (ja) 2011-09-02 2014-11-13 アムジエン・インコーポレーテツド 医薬製品および医薬製品の露光を分析する方法
AR089231A1 (es) 2011-12-15 2014-08-06 Amgen Inc Metodo de floculacion
US20150353542A1 (en) 2013-01-14 2015-12-10 Amgen Inc. Methods of using cell-cycle inhibitors to modulate one or more properties of a cell culture
SI3395423T1 (sl) 2013-03-14 2023-12-29 Amgen Inc. Odstranjevanje izluženega liganda za afinitetno čiščenje
TWI832345B (zh) 2013-03-14 2024-02-11 美商安美基公司 用於增加重組蛋白質之甘露糖含量之方法
TWI614041B (zh) 2013-03-15 2018-02-11 安美基公司 用於注射器之匣盒
US10646664B2 (en) 2013-03-15 2020-05-12 Amgen Inc. Body contour adaptable autoinjector device
JP6336564B2 (ja) 2013-03-15 2018-06-06 アムゲン・インコーポレーテッド 薬物カセット、自動注入器、および自動注入器システム
US9481901B2 (en) 2013-05-30 2016-11-01 Amgen Inc. Methods for increasing mannose content of recombinant proteins
RS66894B1 (sr) 2013-10-31 2025-07-31 Amgen Inc Upotreba monensina za regulaciju glikozilacije rekombinantnih proteina
BR122020004385B1 (pt) 2014-01-13 2022-10-04 Amgen Inc Método para aumentar o teor de glicoforma de alta manose de uma glicoproteína recombinante e método de produção de uma glicoproteína recombinante
US10106829B2 (en) 2014-01-29 2018-10-23 Amgen Inc. Overexpression of N-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
WO2015116315A1 (en) 2014-01-29 2015-08-06 Amgen Inc. Overexpression of n-glycosylation pathway regulators to modulate glycosylation of recombinant proteins
AU2015269365A1 (en) 2014-06-04 2016-12-15 Amgen Inc. Methods for harvesting mammalian cell cultures
US11275090B2 (en) 2014-11-19 2022-03-15 Amgen Inc. Quantitation of glycan moiety in recombinant glycoproteins
CA2969225C (en) 2014-12-01 2023-08-22 Amgen Inc. Process for manipulating the level of glycan content of a glycoprotein
MX2020005066A (es) 2017-11-16 2020-08-20 Amgen Inc Autoinyector con deteccion de detencion y punto final.
IL307155B2 (en) 2018-05-01 2025-11-01 Amgen Inc Antibodies with modulated glycan profiles
KR20220129006A (ko) 2020-01-15 2022-09-22 우시 바이올로직스 아일랜드 리미티드 배양 세포로부터 생산된 생체 물질을 연속적으로 수확하기 위한 장치 및 방법
WO2023079058A1 (en) 2021-11-05 2023-05-11 Yokogawa Insilico Biotechnology Gmbh Cell culture with reduced production of lactate
AU2022424002A1 (en) 2021-12-29 2024-06-13 Bristol-Myers Squibb Company Generation of landing pad cell lines

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4479896A (en) * 1981-12-11 1984-10-30 Antoniades Harry N Method for extraction localization and direct recovery of platelet derived growth factor
EP0487116B1 (de) * 1984-10-12 1999-12-29 ZymoGenetics, Inc. Von Blutplättchen abstammende biologisch aktive Analoga eines Wachstumsfaktors in eukaryotischen Zellen
US4769328A (en) * 1984-10-12 1988-09-06 Zymogenetics Inc. Expression of biologically active PDGF analogs in yeast
US4766073A (en) * 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4801542A (en) * 1984-10-12 1989-01-31 Zymogenetics, Inc. Expression of biologically active PDGF analogs in eucaryotic cells
EP0259632B1 (de) * 1986-08-13 1995-12-13 Zymogenetics, Inc. Expression von biologisch-aktiven PDGF-Analogen in eukaryotischen Zellen
DE3834079A1 (de) * 1988-10-06 1990-04-12 Biotechnolog Forschung Gmbh Wachstumstimulierendes pdgf-bb und dessen verwendung sowie ein verfahren zu seiner herstellung und der des monomeren
IL96682A0 (en) * 1989-12-15 1991-09-16 Amgen Inc Production of biologically active platelet-derived growth factor from high expression host cell systems

Also Published As

Publication number Publication date
AU7153491A (en) 1991-07-18
EP0458959A4 (en) 1993-06-16
NO913232D0 (no) 1991-08-19
FI913892A0 (fi) 1991-08-16
PT96272A (pt) 1991-09-30
AU646014B2 (en) 1994-02-03
ATE123949T1 (de) 1995-07-15
NZ236549A (en) 1993-03-26
DE69020335T2 (de) 1995-11-02
GR3017317T3 (en) 1995-12-31
DE69020335D1 (de) 1995-07-27
US5272064A (en) 1993-12-21
JPH04504064A (ja) 1992-07-23
WO1991008761A1 (en) 1991-06-27
EP0458959B1 (de) 1995-06-21
IE904608A1 (en) 1991-06-19
ES2073735T3 (es) 1995-08-16
FI913892A7 (fi) 1991-08-16
EP0458959A1 (de) 1991-12-04
IL96723A0 (en) 1991-09-16
DK0458959T3 (da) 1995-08-14
CA2032675A1 (en) 1991-06-20

Similar Documents

Publication Publication Date Title
NO913232L (no) Nye blodplatederiverte vekstfaktor-b-kjedeanaloger og metode for homogen produksjon av disse.
ATE84312T1 (de) Expression, in eukaryotischen zellen, von biologisch aktiven analoga eines wachstumsfaktors, abstammend von blutplaettchen.
Fambrough et al. On the similarity of plant and animal histones
DE69125810T2 (de) Verfahren zur enzymatischen herstellung von basischen fibroblasten-wachstumsfaktors
BR8102164A (pt) Processo para sintetizar, dentro de um hospedeiro bacteriano e secretar, atraves da membrana do hospedeiro, uma proteina ou polipeptideo slecionada, bem como veiculo de clonagem e hospedeiro transformado como ultimo
DE122004000009I2 (de) Methode zur Herstellung von menschlichen Wachstumshormonen
ATE117023T1 (de) Verfahren zur herstellung eines physiologisch aktiven peptids mit einem cysteinrest.
ES2093717T3 (es) Mutante de hirudina, su produccion, anticoagulante, vector secretor, microorganismo transformado por el indicado vector y produccion de un producto a partir de dicho microorganismo.
AU7681687A (en) Expression of platelet-derived growth factor and analogues
ES2059854T3 (es) Nuevo polipeptido y su produccion.
BG47040A3 (en) Method for preparing of a- 21978 with cyclic peptidic derivatives
DE69027466D1 (de) Achromobacter-Protease-I-Gen sowie Genprodukt
EP0544293B1 (de) Verfahren zur gentechnologischen Herstellung von biologisch aktivem beta-NGF
DK595187D0 (da) Minactivin og fremgangsmaade til fremstilling deraf
US4308204A (en) Process for preparing the third component of the complement from human blood plasma
US20190077842A1 (en) Method For Producing A Recombinant Protein With Reduced Impurities
Suenaga et al. Further studies on the chemical cleavage of an N-terminal extra methionine from recombinant methionylated proteins
CN109295041A (zh) 具有舍雷肽酶活性的多肽及其制备方法
Fuchs et al. Studies of the effects of ethylene on yeast alcohol dehydrogenase activity
CN120737189A (zh) 具备三螺旋结构的重组型胶原蛋白及其制备方法和应用
JPS6485094A (en) Novel physiologically active polypeptide
Shaar et al. 4885163 Topical use of IGF-II for wound healing
Clark et al. 4868119 Hematopoietic growth factors
Jaye et al. 4868113 Recombinant DNA vector encoding human endothelial cell growth factor
SI8111622B (sl) Interferoni in postopek za njihovo pridobivanje