NO971136L - Aminoalkyl- og acylaminoalkyleter, fremgangsmåte for fremstilling derav og anvendelse som bradykinin-reseptor antagonister - Google Patents
Aminoalkyl- og acylaminoalkyleter, fremgangsmåte for fremstilling derav og anvendelse som bradykinin-reseptor antagonisterInfo
- Publication number
- NO971136L NO971136L NO971136A NO971136A NO971136L NO 971136 L NO971136 L NO 971136L NO 971136 A NO971136 A NO 971136A NO 971136 A NO971136 A NO 971136A NO 971136 L NO971136 L NO 971136L
- Authority
- NO
- Norway
- Prior art keywords
- aminoalkyl
- acylaminoalkyl
- ether
- preparation
- receptor antagonists
- Prior art date
Links
- -1 acylaminoalkyl ether Chemical compound 0.000 title abstract 3
- 125000004103 aminoalkyl group Chemical group 0.000 title abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 title abstract 2
- 229940122155 Bradykinin receptor antagonist Drugs 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 101710085045 B2 bradykinin receptor Proteins 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005741 alkyl alkenyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/24—Oxygen atoms attached in position 8
- C07D215/26—Alcohols; Ethers thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Quinoline Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19609827A DE19609827A1 (de) | 1996-03-13 | 1996-03-13 | Aminoalkyl- und Acylaminoalkylether, Verfahren zu deren Herstellung und ihre Verwendung als Bradykinin-Rezeptorantagonisten |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO971136D0 NO971136D0 (no) | 1997-03-12 |
| NO971136L true NO971136L (no) | 1997-09-15 |
Family
ID=7788139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO971136A NO971136L (no) | 1996-03-13 | 1997-03-12 | Aminoalkyl- og acylaminoalkyleter, fremgangsmåte for fremstilling derav og anvendelse som bradykinin-reseptor antagonister |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US6140341A (cs) |
| EP (1) | EP0795547B1 (cs) |
| JP (1) | JP4317597B2 (cs) |
| KR (1) | KR970065521A (cs) |
| AR (1) | AR006189A1 (cs) |
| AT (1) | ATE192738T1 (cs) |
| AU (1) | AU1621797A (cs) |
| BR (1) | BR9701267A (cs) |
| CA (1) | CA2199771A1 (cs) |
| CZ (1) | CZ76697A3 (cs) |
| DE (2) | DE19609827A1 (cs) |
| DK (1) | DK0795547T3 (cs) |
| ES (1) | ES2148858T3 (cs) |
| GR (1) | GR3033415T3 (cs) |
| HR (1) | HRP970138A2 (cs) |
| HU (1) | HUP9700566A1 (cs) |
| ID (1) | ID16217A (cs) |
| IL (1) | IL120427A0 (cs) |
| NO (1) | NO971136L (cs) |
| PL (1) | PL318923A1 (cs) |
| PT (1) | PT795547E (cs) |
| SI (1) | SI0795547T1 (cs) |
| SK (1) | SK32097A3 (cs) |
| TR (1) | TR199700184A2 (cs) |
| TW (1) | TW363891B (cs) |
| ZA (1) | ZA972129B (cs) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6376670B1 (en) | 1997-06-19 | 2002-04-23 | Sepracor Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| US6172084B1 (en) | 1997-06-19 | 2001-01-09 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| US6207679B1 (en) | 1997-06-19 | 2001-03-27 | Sepracor, Inc. | Antimicrobial agents uses and compositions related thereto |
| US6103905A (en) * | 1997-06-19 | 2000-08-15 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| EP1914236A1 (en) | 2002-04-10 | 2008-04-23 | Ortho-McNeil Pharmaceutical, Inc. | Novel heteroaryl alkylamide derivatives useful as bradykinin receptor modulators |
| ITMI20021247A1 (it) * | 2002-06-07 | 2003-12-09 | Menarini Ricerche Spa | Antagonisti basici non peptidici della bradichinina e loro impiego informulazioni farmaceutiche |
| TWI407960B (zh) | 2007-03-23 | 2013-09-11 | Jerini Ag | 小分子緩激肽ｂ２受體調節劑 |
| MY156662A (en) * | 2007-11-01 | 2016-03-15 | Acucela Inc | Amine derivative compounds for treating ophthalmic diseases and disorders |
| AR113839A1 (es) | 2017-11-24 | 2020-06-17 | Pharvaris B V | Antagonistas del receptor b2 de bradiquinina |
| AR118983A1 (es) | 2019-05-23 | 2021-11-17 | Pharvaris Gmbh | Antagonistas cíclicos del receptor b2 de bradiquinina |
| UY38706A (es) | 2019-05-23 | 2020-12-31 | Pharvaris Gmbh | Antagonistas cíclicos del receptor b2 de bradiquinina |
| MA61123B1 (fr) | 2021-08-05 | 2024-06-28 | Pharvaris Gmbh | Composition à base de lipides pour l'administration par voie orale d'antagonistes des récepteurs b2 de la bradykinine |
| ES3062067T3 (en) | 2022-03-25 | 2026-04-08 | Pharvaris Gmbh | Solid composition comprising solubilised bradykinin b2-receptor antagonists |
| US20250268887A1 (en) | 2022-03-25 | 2025-08-28 | Pharvaris Gmbh | Therapeutic uses of bradykinin b2-receptor antagonists |
| TW202345810A (zh) | 2022-03-25 | 2023-12-01 | 瑞士商帕法瑞斯有限責任公司 | 包含緩激肽ｂ２受體拮抗劑之固態延長釋放組成物 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5216165A (en) * | 1990-10-03 | 1993-06-01 | American Home Products Corporation | N-substituted aminoquinolines as analgesic agents |
| US5288725A (en) * | 1992-10-15 | 1994-02-22 | Merck & Co., Inc. | Pyrroloquinoline Bradykinin antagonist |
| AU680870B2 (en) * | 1993-04-28 | 1997-08-14 | Astellas Pharma Inc. | New heterocyclic compounds |
| US6756388B1 (en) * | 1993-10-12 | 2004-06-29 | Pfizer Inc. | Benzothiophenes and related compounds as estrogen agonists |
| ES2218554T3 (es) * | 1994-10-27 | 2004-11-16 | Fujisawa Pharmaceutical Co., Ltd. | Piridopirimidonas, quinolinas y n-heterociclos condensados que son antagonistas de bradiquinina. |
| FR2735128B1 (fr) * | 1995-06-07 | 1997-07-25 | Fournier Ind & Sante | Nouveaux composes de benzenesulfonamide, leur procede de preparation et utilisation en therapeutique. |
| FR2737892B1 (fr) * | 1995-08-17 | 1997-10-24 | Fournier Ind & Sante | Nouveaux composes de benzenesulfonamide, procede de preparation et utilisation en therapeutique |
-
1996
- 1996-03-13 DE DE19609827A patent/DE19609827A1/de not_active Withdrawn
-
1997
- 1997-02-27 DE DE59701617T patent/DE59701617D1/de not_active Expired - Lifetime
- 1997-02-27 ES ES97103163T patent/ES2148858T3/es not_active Expired - Lifetime
- 1997-02-27 PT PT97103163T patent/PT795547E/pt unknown
- 1997-02-27 AT AT97103163T patent/ATE192738T1/de not_active IP Right Cessation
- 1997-02-27 DK DK97103163T patent/DK0795547T3/da active
- 1997-02-27 SI SI9730063T patent/SI0795547T1/xx unknown
- 1997-02-27 EP EP97103163A patent/EP0795547B1/de not_active Expired - Lifetime
- 1997-03-10 ID IDP970758A patent/ID16217A/id unknown
- 1997-03-11 SK SK320-97A patent/SK32097A3/sk unknown
- 1997-03-11 AU AU16217/97A patent/AU1621797A/en not_active Abandoned
- 1997-03-11 TW TW086102960A patent/TW363891B/zh active
- 1997-03-11 AR ARP970100968A patent/AR006189A1/es unknown
- 1997-03-11 HU HU9700566A patent/HUP9700566A1/hu unknown
- 1997-03-11 TR TR97/00184A patent/TR199700184A2/xx unknown
- 1997-03-12 NO NO971136A patent/NO971136L/no unknown
- 1997-03-12 HR HR19609827.0A patent/HRP970138A2/xx not_active Application Discontinuation
- 1997-03-12 CZ CZ97766A patent/CZ76697A3/cs unknown
- 1997-03-12 KR KR1019970008175A patent/KR970065521A/ko not_active Withdrawn
- 1997-03-12 PL PL97318923A patent/PL318923A1/xx unknown
- 1997-03-12 CA CA002199771A patent/CA2199771A1/en not_active Abandoned
- 1997-03-12 BR BR9701267A patent/BR9701267A/pt unknown
- 1997-03-12 IL IL12042797A patent/IL120427A0/xx unknown
- 1997-03-12 US US08/820,321 patent/US6140341A/en not_active Expired - Fee Related
- 1997-03-12 ZA ZA9702129A patent/ZA972129B/xx unknown
- 1997-03-12 JP JP05783497A patent/JP4317597B2/ja not_active Expired - Fee Related
-
2000
- 2000-05-16 GR GR20000401105T patent/GR3033415T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| AU1621797A (en) | 1997-09-18 |
| DE59701617D1 (de) | 2000-06-15 |
| ZA972129B (en) | 1997-09-15 |
| EP0795547A1 (de) | 1997-09-17 |
| ATE192738T1 (de) | 2000-05-15 |
| TW363891B (en) | 1999-07-11 |
| CZ76697A3 (en) | 1997-10-15 |
| JP4317597B2 (ja) | 2009-08-19 |
| KR970065521A (ko) | 1997-10-13 |
| TR199700184A2 (xx) | 1997-10-21 |
| PL318923A1 (en) | 1997-09-15 |
| HRP970138A2 (en) | 1998-04-30 |
| MX9701857A (es) | 1997-09-30 |
| HU9700566D0 (en) | 1997-04-28 |
| DE19609827A1 (de) | 1997-09-18 |
| ID16217A (id) | 1997-09-11 |
| PT795547E (pt) | 2000-10-31 |
| DK0795547T3 (da) | 2000-09-18 |
| EP0795547B1 (de) | 2000-05-10 |
| GR3033415T3 (en) | 2000-09-29 |
| SI0795547T1 (en) | 2000-10-31 |
| BR9701267A (pt) | 1999-01-12 |
| AR006189A1 (es) | 1999-08-11 |
| JPH101472A (ja) | 1998-01-06 |
| US6140341A (en) | 2000-10-31 |
| HUP9700566A1 (hu) | 2000-08-28 |
| CA2199771A1 (en) | 1997-09-13 |
| IL120427A0 (en) | 1997-07-13 |
| NO971136D0 (no) | 1997-03-12 |
| SK32097A3 (en) | 1998-01-14 |
| ES2148858T3 (es) | 2000-10-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO971136L (no) | Aminoalkyl- og acylaminoalkyleter, fremgangsmåte for fremstilling derav og anvendelse som bradykinin-reseptor antagonister | |
| HRP20000182B1 (en) | Processes and intermediates for preparing anti-cancer compounds | |
| EA200001135A1 (ru) | Способ получения изоксазолин-3-ил-ацилбензолов | |
| NO20054300L (no) | Prosess for fremstilling av fenetylaminderivater | |
| PT80942A (fr) | Procede de preparation de nouveaux derives du pyrrole | |
| PL378201A1 (pl) | Sposób farmaceutyczny oraz związki wytwarzane tym sposobem | |
| NO990335L (no) | Arylsykloalkankarboksylestere, anvendelse derav, farmas°ytiske sammensetninger og fremstilling | |
| NZ201514A (en) | 1-phenyl-2-substituted aminocarbonyl indole compounds and pharmaceutical compositions | |
| CA1055032A (en) | Process for the preparation of thieno (3,2-c) pyridine and thieno (2,3-c) pyridine | |
| ES8606228A1 (es) | Un procedimiento para separar los antipodas opticos de 1-pi-ridil-alquil-4-aril-piperazinas | |
| NO960441L (no) | Benzopyraner og farmasöytiske forbindelser inneholdende dem | |
| EA200200611A1 (ru) | Новые тетрагидропиридины, способ их получения и содержащие их фармацевтические композиции | |
| DE3468104D1 (en) | New aryloxypropanolamine derivatives, process for the preparation thereof, pharmaceutical compositions and therapeutic use | |
| Atkins et al. | Pseudohalogen chemistry. XI. Some aspects of the chemistry of α-thiocyanato-β-dicarbonyl compounds | |
| El‐Deen | Use of 3–(2′‐formyl‐1′‐chlorovinyl) coumarin in the syntheses of pyrazol, salicylaldazine and pyrimidine derivatives | |
| ES8400743A1 (es) | "procedimiento para la preparacion de compuestos de 1-fenilindazol-3-ona". | |
| CA2263268A1 (en) | Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers | |
| Tasaka et al. | Synthesis of 2‐phenylimidazo [2, 1‐b] benzothiazole derivatives as modulators of multidrug resistance for tumor cells | |
| Tamura et al. | Mono‐N‐amino salt of benzodiazines and naphthyridines | |
| SU640663A3 (ru) | Способ получени производных нитрохиназолинона | |
| Wang et al. | A Novel Synthesis of Thieno [2, 3-C] pyrazole | |
| CA1193255A (en) | Benzylazone derivatives | |
| SE8502973D0 (sv) | Framstellning av aminderivat | |
| JPS5470277A (en) | Hydroxyindole derivatives | |
| US3239526A (en) | 3-phenyl-4-aminocinnolines |