NO984740D0 - Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler - Google Patents

Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler

Info

Publication number
NO984740D0
NO984740D0 NO984740A NO984740A NO984740D0 NO 984740 D0 NO984740 D0 NO 984740D0 NO 984740 A NO984740 A NO 984740A NO 984740 A NO984740 A NO 984740A NO 984740 D0 NO984740 D0 NO 984740D0
Authority
NO
Norway
Prior art keywords
analgesics
acetylcholinesterase inhibitors
isatin derivatives
isatin
derivatives
Prior art date
Application number
NO984740A
Other languages
English (en)
Norwegian (no)
Other versions
NO984740L (no
Inventor
Stephen James Shimshock
Abdul Ezaz Mutlib
Susan Marie Chesson
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of NO984740L publication Critical patent/NO984740L/no
Publication of NO984740D0 publication Critical patent/NO984740D0/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
NO984740A 1996-04-12 1998-10-09 Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler NO984740D0 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US63187096A 1996-04-12 1996-04-12
PCT/US1997/003598 WO1997038993A1 (en) 1996-04-12 1997-03-07 Isatin derivatives as acetylcholinesterase inhibitors and analgesics

Publications (2)

Publication Number Publication Date
NO984740L NO984740L (no) 1998-10-09
NO984740D0 true NO984740D0 (no) 1998-10-09

Family

ID=24533114

Family Applications (1)

Application Number Title Priority Date Filing Date
NO984740A NO984740D0 (no) 1996-04-12 1998-10-09 Isatinderivater som acetylcholinesteraseinhibitorer og analgetiske midler

Country Status (19)

Country Link
EP (1) EP0892796B1 (da)
JP (1) JP4109718B2 (da)
KR (1) KR20000005379A (da)
CN (1) CN1215399A (da)
AR (1) AR006606A1 (da)
AT (1) ATE207483T1 (da)
BR (1) BR9708655A (da)
CA (1) CA2252039C (da)
DE (1) DE69707659T2 (da)
DK (1) DK0892796T3 (da)
ES (1) ES2165586T3 (da)
GR (1) GR3037006T3 (da)
HU (1) HUP9903473A3 (da)
IL (1) IL126308A0 (da)
NO (1) NO984740D0 (da)
PT (1) PT892796E (da)
TW (1) TW426678B (da)
WO (1) WO1997038993A1 (da)
ZA (1) ZA972990B (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6218383B1 (en) 1998-08-07 2001-04-17 Targacept, Inc. Pharmaceutical compositions for the prevention and treatment of central nervous system disorders
US8278345B2 (en) 2006-11-09 2012-10-02 Probiodrug Ag Inhibitors of glutaminyl cyclase
ATE554085T1 (de) 2006-11-30 2012-05-15 Probiodrug Ag Neue inhibitoren von glutaminylcyclase
JP5930573B2 (ja) 2007-03-01 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤の新規使用
EP2142514B1 (en) 2007-04-18 2014-12-24 Probiodrug AG Thiourea derivatives as glutaminyl cyclase inhibitors
JP5934645B2 (ja) 2009-09-11 2016-06-15 プロビオドルグ エージー グルタミニルシクラーゼ阻害剤としてのヘテロ環式誘導体
AU2011215870B2 (en) 2010-02-09 2016-01-28 The Johns Hopkins University Methods and compositions for improving cognitive function
CA2788656A1 (en) 2010-02-16 2011-08-25 Pfizer Inc. (r)-4-((4-((4-(tetrahydrofuran-3-yloxy)benzo[d]isoxazol-3-yloxy)methyl)piperidin-1-yl)methyl)tetrahydro-2h-pyran-4-ol, a partial agonist of 5-ht4 receptors
JP6026284B2 (ja) 2010-03-03 2016-11-16 プロビオドルグ エージー グルタミニルシクラーゼの阻害剤
NZ602312A (en) 2010-03-10 2014-02-28 Probiodrug Ag Heterocyclic inhibitors of glutaminyl cyclase (qc, ec 2.3.2.5)
WO2011131748A2 (en) 2010-04-21 2011-10-27 Probiodrug Ag Novel inhibitors
EP2686313B1 (en) 2011-03-16 2016-02-03 Probiodrug AG Benzimidazole derivatives as inhibitors of glutaminyl cyclase
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
PL2931276T3 (pl) 2012-12-13 2018-06-29 H. Lundbeck A/S Kompozycje zawierające wortioksetynę i donepezil
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
JP6433482B2 (ja) 2013-03-15 2018-12-05 エージンバイオ, インコーポレイテッド 認知機能を改善するための方法および組成物
US10537552B2 (en) 2015-05-05 2020-01-21 Carafe Drug Innovation, Llc Substituted 5-hydroxyoxindoles and their use as analgesics and fever reducers
WO2016191288A1 (en) 2015-05-22 2016-12-01 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
ES2812698T3 (es) 2017-09-29 2021-03-18 Probiodrug Ag Inhibidores de glutaminil ciclasa
WO2023081800A1 (en) * 2021-11-05 2023-05-11 The Regents Of The University Of California Alpha-2a adrenergic receptor modulators and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5296488A (en) * 1989-08-02 1994-03-22 Hoechst-Roussel Pharmaceuticals Inc. Method of using 2,3-dihydro-1-(pyridinylamino)-indoles as anticonvulsants and for the enhancement of memory
US5006537A (en) * 1989-08-02 1991-04-09 Hoechst-Roussel Pharmaceuticals, Inc. 1,3-dihydro-1-(pyridinylamino)-2H-indol-2-ones
US4994472A (en) * 1989-08-02 1991-02-19 Hoechst-Roussel Pharmaceuticals Incorporated 1-(pyridinylamino)-2-pyrrolidinones as pain relievers

Also Published As

Publication number Publication date
WO1997038993A1 (en) 1997-10-23
DE69707659T2 (de) 2002-05-08
CA2252039A1 (en) 1997-10-23
IL126308A0 (en) 1999-05-09
AU716997B2 (en) 2000-03-16
ZA972990B (en) 1997-11-03
NO984740L (no) 1998-10-09
EP0892796A1 (en) 1999-01-27
HUP9903473A3 (en) 2000-09-28
PT892796E (pt) 2002-03-28
JP2001508400A (ja) 2001-06-26
GR3037006T3 (en) 2002-01-31
AU2072597A (en) 1997-11-07
ES2165586T3 (es) 2002-03-16
EP0892796B1 (en) 2001-10-24
KR20000005379A (en) 2000-01-25
ATE207483T1 (de) 2001-11-15
DE69707659D1 (de) 2001-11-29
DK0892796T3 (da) 2001-11-19
TW426678B (en) 2001-03-21
JP4109718B2 (ja) 2008-07-02
BR9708655A (pt) 1999-08-03
AR006606A1 (es) 1999-09-08
HUP9903473A2 (hu) 2000-05-28
CA2252039C (en) 2002-12-24
CN1215399A (zh) 1999-04-28

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