PL1999154T3 - Skonstruowane metodami inżynierii heterodimeryczne domeny białkowe - Google Patents

Skonstruowane metodami inżynierii heterodimeryczne domeny białkowe

Info

Publication number
PL1999154T3
PL1999154T3 PL07723539T PL07723539T PL1999154T3 PL 1999154 T3 PL1999154 T3 PL 1999154T3 PL 07723539 T PL07723539 T PL 07723539T PL 07723539 T PL07723539 T PL 07723539T PL 1999154 T3 PL1999154 T3 PL 1999154T3
Authority
PL
Poland
Prior art keywords
protein domains
heterodimeric protein
engineered heterodimeric
engineered
domains
Prior art date
Application number
PL07723539T
Other languages
English (en)
Inventor
Jonathan H Davis
James Stafford Huston
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of PL1999154T3 publication Critical patent/PL1999154T3/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/246—IL-2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/468—Immunoglobulins having two or more different antigen binding sites, e.g. multifunctional antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/524—CH2 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/52—Constant or Fc region; Isotype
    • C07K2317/526—CH3 domain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL07723539T 2006-03-24 2007-03-23 Skonstruowane metodami inżynierii heterodimeryczne domeny białkowe PL1999154T3 (pl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78547406P 2006-03-24 2006-03-24
EP20070723539 EP1999154B1 (en) 2006-03-24 2007-03-23 Engineered heterodimeric protein domains
PCT/EP2007/002590 WO2007110205A2 (en) 2006-03-24 2007-03-23 Engineered heterodimeric protein domains

Publications (1)

Publication Number Publication Date
PL1999154T3 true PL1999154T3 (pl) 2013-03-29

Family

ID=38541456

Family Applications (1)

Application Number Title Priority Date Filing Date
PL07723539T PL1999154T3 (pl) 2006-03-24 2007-03-23 Skonstruowane metodami inżynierii heterodimeryczne domeny białkowe

Country Status (13)

Country Link
US (4) US8871912B2 (pl)
EP (1) EP1999154B1 (pl)
JP (3) JP5474531B2 (pl)
AR (1) AR060070A1 (pl)
AU (1) AU2007229698B9 (pl)
CA (1) CA2646965C (pl)
DK (1) DK1999154T3 (pl)
ES (1) ES2395969T3 (pl)
IL (1) IL194145A (pl)
PL (1) PL1999154T3 (pl)
PT (1) PT1999154E (pl)
SI (1) SI1999154T1 (pl)
WO (1) WO2007110205A2 (pl)

Families Citing this family (644)

* Cited by examiner, † Cited by third party
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IL194145A (en) 2013-11-28
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