PL2457908T3 - Sposób wytwarzania związków przydatnych jako inhibitory SGLT - Google Patents

Sposób wytwarzania związków przydatnych jako inhibitory SGLT

Info

Publication number
PL2457908T3
PL2457908T3 PL12156039T PL12156039T PL2457908T3 PL 2457908 T3 PL2457908 T3 PL 2457908T3 PL 12156039 T PL12156039 T PL 12156039T PL 12156039 T PL12156039 T PL 12156039T PL 2457908 T3 PL2457908 T3 PL 2457908T3
Authority
PL
Poland
Prior art keywords
sglt
inhibitors
preparation
compounds useful
compounds
Prior art date
Application number
PL12156039T
Other languages
English (en)
Inventor
Walter Ferdinand Maria Filliers
Patrick Hubert J. Nieste
Masanori Hatsuda
Masahiko Yoshinaga
Mitsuhiro Yada
Christopher Teleha
Rudy Laurent Maria Broeckx
Original Assignee
Janssen Pharmaceutica N.V.
Mitsubishi Tanabe Pharma Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42106967&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2457908(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Janssen Pharmaceutica N.V., Mitsubishi Tanabe Pharma Corporation filed Critical Janssen Pharmaceutica N.V.
Publication of PL2457908T3 publication Critical patent/PL2457908T3/pl

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/381—Heterocyclic compounds having sulfur as a ring hetero atom having five-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/12—Radicals substituted by halogen atoms or nitro or nitroso radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Diabetes (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
PL12156039T 2008-10-17 2009-10-15 Sposób wytwarzania związków przydatnych jako inhibitory SGLT PL2457908T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10623108P 2008-10-17 2008-10-17
US10626008P 2008-10-17 2008-10-17
US12/578,934 US9056850B2 (en) 2008-10-17 2009-10-14 Process for the preparation of compounds useful as inhibitors of SGLT
EP12156039.5A EP2457908B8 (en) 2008-10-17 2009-10-15 Process for the Preparation of Compounds useful as inhibitors of SGLT

Publications (1)

Publication Number Publication Date
PL2457908T3 true PL2457908T3 (pl) 2017-08-31

Family

ID=42106967

Family Applications (3)

Application Number Title Priority Date Filing Date
PL12156035T PL2455374T3 (pl) 2008-10-17 2009-10-15 Sposób wytwarzania związków przydatnych jako inhibitory SGLT
PL12156039T PL2457908T3 (pl) 2008-10-17 2009-10-15 Sposób wytwarzania związków przydatnych jako inhibitory SGLT
PL09736928T PL2346888T3 (pl) 2008-10-17 2009-10-15 Sposób wytwarzania związków przydatnych jako inhibitory SGLT

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PL12156035T PL2455374T3 (pl) 2008-10-17 2009-10-15 Sposób wytwarzania związków przydatnych jako inhibitory SGLT

Family Applications After (1)

Application Number Title Priority Date Filing Date
PL09736928T PL2346888T3 (pl) 2008-10-17 2009-10-15 Sposób wytwarzania związków przydatnych jako inhibitory SGLT

Country Status (30)

Country Link
US (1) US9056850B2 (pl)
EP (3) EP2455374B1 (pl)
JP (3) JP6123111B2 (pl)
KR (2) KR101724598B1 (pl)
CN (3) CN105541814A (pl)
AR (1) AR073892A1 (pl)
AU (1) AU2009305413B2 (pl)
BR (1) BRPI0920356B1 (pl)
CA (2) CA2946212C (pl)
CL (1) CL2011000849A1 (pl)
CY (3) CY1113867T1 (pl)
DK (3) DK2346888T3 (pl)
EA (1) EA021373B1 (pl)
ES (3) ES2854598T3 (pl)
HK (1) HK1224289A1 (pl)
HR (3) HRP20130254T1 (pl)
HU (2) HUE052432T2 (pl)
IL (2) IL212270A0 (pl)
LT (2) LT2455374T (pl)
MX (1) MX2011004054A (pl)
NZ (1) NZ592204A (pl)
PL (3) PL2455374T3 (pl)
PT (3) PT2455374T (pl)
RS (3) RS55577B1 (pl)
SI (3) SI2346888T1 (pl)
SM (4) SMT202100072T1 (pl)
TW (3) TW201613905A (pl)
UA (1) UA107450C2 (pl)
WO (1) WO2010043682A2 (pl)
ZA (1) ZA201103587B (pl)

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JP5658751B2 (ja) 2009-07-10 2015-01-28 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプＪａｎｓｓｅｎ Ｐｈａｒｍａｃｅｕｔｉｃａ Ｎａａｍｌｏｚｅ Ｖｅｎｎｏｏｔｓｃｈａｐ １−（β−Ｄ−グルコピラノシル）−４−メチル−３−［５−（４−フルオロフェニル）−２−チエニルメチル］ベンゼンのための結晶化方法
WO2011047113A1 (en) * 2009-10-14 2011-04-21 Janssen Pharmaceutica Nv Process for the preparation of compounds useful as inhibitors of sglt2
US8163704B2 (en) 2009-10-20 2012-04-24 Novartis Ag Glycoside derivatives and uses thereof
NZ703128A (en) * 2010-05-11 2016-04-29 Janssen Pharmaceutica Nv Pharmaceutical formulations comprising 1 - (beta-d-glucopyranosyl) - 2 -thienylmethylbenzene derivatives as inhibitors of sglt
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WO2012140120A1 (en) 2011-04-13 2012-10-18 Janssen Pharmaceutica Nv Process for the preparation of compounds useful as inhibitors of sglt2
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CN104119324B (zh) * 2014-07-23 2016-03-30 齐鲁天和惠世制药有限公司 一种卡格列净的制备方法
CN104292209A (zh) * 2014-09-11 2015-01-21 浙江丽晶化学有限公司 一种制备2-(4-氟苯基)噻吩(化合物v)的新方法
CN104402946B (zh) * 2014-11-17 2018-01-02 连云港恒运药业有限公司 卡格列净中间体及其无定形的制备方法
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KR102932313B1 (ko) * 2019-02-15 2026-02-26 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 Nrf2 활성화제로서 히드록시피리드옥사제핀
CN110698468B (zh) * 2019-09-24 2020-11-03 杭州华东医药集团新药研究院有限公司 一种坎格列净的制备方法
CN111057049B (zh) * 2019-11-18 2021-06-01 杭州华东医药集团新药研究院有限公司 一种卡格列净半水化合物的制备方法
CN113943329A (zh) * 2020-07-16 2022-01-18 尚科生物医药（上海）有限公司 一种坎格列净中间体的非对映异构体的制备方法
WO2022107463A1 (ja) 2020-11-18 2022-05-27 株式会社トクヤマ ケトン誘導体の製造方法
CN112608299A (zh) * 2020-12-24 2021-04-06 山东铂源药业有限公司 一种4-(6-氨基吡啶-3-基)哌啶-1-甲酸叔丁酯的合成方法
CN113372326A (zh) * 2021-06-23 2021-09-10 江苏法安德医药科技有限公司 一种2-(4-氟苯基)噻吩的分离提纯方法
CN113429379A (zh) * 2021-06-28 2021-09-24 江苏法安德医药科技有限公司 一种lh-1801中间体及其制备方法和应用
JPWO2023080243A1 (pl) * 2021-11-08 2023-05-11
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