PL366141A1 - Kompleksy litowe N-(1-hydroksymetylo-2,3-dihydroksypropylo)-1-4-7-trikarboksymetylo-1,4,7,10-tetraazacyklododekanu, ich wytwarzanie i zastosowanie - Google Patents

Kompleksy litowe N-(1-hydroksymetylo-2,3-dihydroksypropylo)-1-4-7-trikarboksymetylo-1,4,7,10-tetraazacyklododekanu, ich wytwarzanie i zastosowanie

Info

Publication number
PL366141A1
PL366141A1 PL01366141A PL36614101A PL366141A1 PL 366141 A1 PL366141 A1 PL 366141A1 PL 01366141 A PL01366141 A PL 01366141A PL 36614101 A PL36614101 A PL 36614101A PL 366141 A1 PL366141 A1 PL 366141A1
Authority
PL
Poland
Prior art keywords
triscarboxymethyl
tetraazacyclododecane
dihydroxypropyl
hydroxymethyl
production
Prior art date
Application number
PL01366141A
Other languages
English (en)
Other versions
PL204181B1 (pl
Inventor
Johannes Platzek
Peter Blaszkiewicz
Orlin Petrov
Holger Hoffmann
Original Assignee
Schering Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Aktiengesellschaft filed Critical Schering Aktiengesellschaft
Publication of PL366141A1 publication Critical patent/PL366141A1/pl
Publication of PL204181B1 publication Critical patent/PL204181B1/pl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F1/00—Compounds containing elements of Groups 1 or 11 of the Periodic Table
    • C07F1/02—Lithium compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PL366141A 2000-12-15 2001-12-05 Kompleksy litowe N-(1-hydroksymetylo-2,3-dihydroksypropylo)-1,4,7-trikarboksymetylo-1,4,7,10-tetraazacyklododekanu, sposób ich wytwarzania i zastosowanie PL204181B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10064467A DE10064467C2 (de) 2000-12-15 2000-12-15 Lithium-Komplexe von N-(1-Hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecan, deren Herstellung und Verwendung
PCT/EP2001/014283 WO2002048119A2 (de) 2000-12-15 2001-12-05 Lithium-komplexe von n-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecan, deren herstellung und verwendung

Publications (2)

Publication Number Publication Date
PL366141A1 true PL366141A1 (pl) 2005-01-24
PL204181B1 PL204181B1 (pl) 2009-12-31

Family

ID=7668584

Family Applications (1)

Application Number Title Priority Date Filing Date
PL366141A PL204181B1 (pl) 2000-12-15 2001-12-05 Kompleksy litowe N-(1-hydroksymetylo-2,3-dihydroksypropylo)-1,4,7-trikarboksymetylo-1,4,7,10-tetraazacyklododekanu, sposób ich wytwarzania i zastosowanie

Country Status (34)

Country Link
US (1) US6894151B2 (pl)
EP (1) EP1343770B1 (pl)
JP (1) JP4399163B2 (pl)
KR (1) KR100869627B1 (pl)
CN (1) CN1229357C (pl)
AR (1) AR035609A1 (pl)
AT (1) ATE430737T1 (pl)
AU (2) AU3165902A (pl)
BG (1) BG66117B1 (pl)
BR (1) BR0116219A (pl)
CA (1) CA2431976C (pl)
CY (1) CY1109280T1 (pl)
CZ (1) CZ304573B6 (pl)
DE (2) DE10064467C2 (pl)
DK (1) DK1343770T3 (pl)
EC (1) ECSP034676A (pl)
EE (1) EE05245B1 (pl)
ES (1) ES2325982T3 (pl)
HR (1) HRP20030576B1 (pl)
HU (1) HU229657B1 (pl)
IL (1) IL156432A0 (pl)
ME (1) ME00157B (pl)
MX (1) MXPA03005240A (pl)
NO (1) NO324864B1 (pl)
NZ (1) NZ526478A (pl)
PL (1) PL204181B1 (pl)
PT (1) PT1343770E (pl)
RS (1) RS51862B (pl)
RU (1) RU2003120513A (pl)
SK (1) SK287424B6 (pl)
TW (1) TWI302531B (pl)
UY (1) UY27056A1 (pl)
WO (1) WO2002048119A2 (pl)
ZA (1) ZA200305421B (pl)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007521254A (ja) * 2003-06-25 2007-08-02 ゲルベ 診断画像用化合物
FR2867473B1 (fr) 2004-03-12 2006-06-23 Guerbet Sa Compose de porphyrines et utilisation a haut champ en irm
CN101090739B (zh) * 2004-07-02 2012-10-10 伯拉考成像股份公司 磁共振成像中用作高弛豫造影剂配体的1，4-二（羧甲基）氨基-6-甲基-全氢-1，4-二氮杂*（aazta)衍生物
CA2645668A1 (en) 2006-03-14 2007-09-20 Mallinckrodt Inc. Metal complexes of tetraazamacrocycle derivatives
US7777029B2 (en) * 2006-05-02 2010-08-17 San Diego State University (Sdsu) Foundation Bifunctional chelators for sequestering lanthanides
DE102009053252B3 (de) * 2009-11-09 2011-09-01 Bayer Schering Pharma Aktiengesellschaft Gadobutrolherstellung mittels keramischer Membran
WO2011054480A1 (de) * 2009-11-09 2011-05-12 Bayer Schering Pharma Aktiengesellschaft Gadobutrolherstellung mittels keramischer membran
DE102009057274B4 (de) 2009-12-02 2011-09-01 Bayer Schering Pharma Aktiengesellschaft Gadobutrolherstellung mittels Trioxobicyclo-octan
DE102010013833A1 (de) 2010-03-29 2011-09-29 Bayer Schering Pharma Aktiengesellschaft Herstellung von Gadobutrol mittels Dimethylformamiddimethylacetal
DE102010023105A1 (de) 2010-06-04 2011-12-08 Bayer Schering Pharma Aktiengesellschaft Gadobutrolherstellung im Eintopfverfahren mittels DMF-acetal und N-Methylimidazol
KR20200059319A (ko) 2011-04-21 2020-05-28 바이엘 인텔렉쳐 프로퍼티 게엠베하 고순도 가도부트롤의 제조
CN106543094A (zh) * 2016-11-04 2017-03-29 嘉实（湖南）医药科技有限公司 高纯度钆布醇的制备方法
KR101971435B1 (ko) * 2017-08-29 2019-04-24 주식회사 엔지켐생명과학 가도부트롤 중간체 및 이를 이용한 가도부트롤의 제조 방법
KR102033964B1 (ko) * 2018-01-19 2019-10-18 주식회사 엔지켐생명과학 가도테리돌 중간체 및 이를 이용한 가도테리돌 제조방법
CN111039885B (zh) * 2019-12-06 2021-03-05 广州康瑞泰药业有限公司 一种制备高纯度考布曲钙的方法
KR20210112910A (ko) * 2020-03-06 2021-09-15 주식회사 엔지켐생명과학 가도부트롤 주사제 제조를 위한 부형제인 칼코부트롤의 제조 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4009119A1 (de) * 1990-03-19 1991-09-26 Schering Ag 1,4,7,10-tetraazacyclododecan-butyltriole, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel
DE19724186C2 (de) * 1997-06-02 2002-07-18 Schering Ag Verfahren zur Mono- und 1,7-Bis-N-ß-Hydroxyalkylierung von Cyclen und die entsprechenden N-ß-Hydroxyalkyl-1,4,7,10-tetraazacyclododecan-Li-Salz-Komplexe

Also Published As

Publication number Publication date
SK7292003A3 (en) 2003-11-04
DE10064467A1 (de) 2002-07-11
AU2002231659B2 (en) 2007-07-05
EE200300282A (et) 2003-10-15
DE10064467C2 (de) 2002-10-31
BG107901A (bg) 2004-06-30
BG66117B1 (bg) 2011-05-31
US20020128472A1 (en) 2002-09-12
TWI302531B (en) 2008-11-01
RU2003120513A (ru) 2004-12-27
CN1481371A (zh) 2004-03-10
HRP20030576A2 (en) 2005-06-30
EE05245B1 (et) 2009-12-15
WO2002048119A2 (de) 2002-06-20
NO20032523L (no) 2003-06-04
NO324864B1 (no) 2007-12-17
MEP15708A (en) 2010-06-10
AU3165902A (en) 2002-06-24
US6894151B2 (en) 2005-05-17
CA2431976A1 (en) 2002-06-20
UY27056A1 (es) 2002-07-31
IL156432A0 (en) 2004-01-04
ATE430737T1 (de) 2009-05-15
CN1229357C (zh) 2005-11-30
WO2002048119A3 (de) 2002-11-07
NO20032523D0 (no) 2003-06-04
KR100869627B1 (ko) 2008-11-21
NZ526478A (en) 2006-04-28
ECSP034676A (es) 2003-08-29
HU229657B1 (en) 2014-03-28
HUP0302563A2 (hu) 2003-12-29
HUP0302563A3 (en) 2011-04-28
SK287424B6 (sk) 2010-09-07
BR0116219A (pt) 2006-02-21
ES2325982T3 (es) 2009-09-28
EP1343770B1 (de) 2009-05-06
JP2004515545A (ja) 2004-05-27
AR035609A1 (es) 2004-06-16
YU48103A (sh) 2006-05-25
KR20030077555A (ko) 2003-10-01
RS51862B (sr) 2012-02-29
DK1343770T3 (da) 2009-08-10
CY1109280T1 (el) 2014-07-02
CZ20031641A3 (cs) 2003-09-17
CZ304573B6 (cs) 2014-07-16
HRP20030576B1 (en) 2011-09-30
JP4399163B2 (ja) 2010-01-13
PT1343770E (pt) 2009-07-20
CA2431976C (en) 2010-04-13
MXPA03005240A (es) 2003-09-25
EP1343770A2 (de) 2003-09-17
PL204181B1 (pl) 2009-12-31
HK1064098A1 (en) 2005-01-21
DE50114889D1 (de) 2009-06-18
ZA200305421B (en) 2004-08-27
ME00157B (me) 2010-10-10

Similar Documents

Publication Publication Date Title
AU3165902A (en) Lithium complexes of n-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane, production and use thereof
AU2002231659A1 (en) Lithium complexes of N-(1-hydroxymethyl-2,3-dihydroxypropyl)-1,4,7-triscarboxymethyl-1,4,7,10-tetraazacyclododecane, production and use thereof
AU2465401A (en) Catechins and green tea extract for the treatment of amyloidosis in alzheimer's disease and other amyloidoses
HUP0300924A3 (en) Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
HUP0301764A3 (en) Fungicidal heterocyclic aromatic amides and their compositions, methods of use and preparation
AP2003002764A0 (en) New thiadiazoles and oxadiazoles and their use as phosphodiesterase-7- inhibitors
AU6692701A (en) 3'-prodrugs of 2'-deoxy-beta-L-nucleosides
PL356769A1 (pl) Nowe związki heterocykliczne oraz ich sole i ich zastosowanie medyczne
GB0003254D0 (en) Heterocyclic compounds and their therapeutic use
PL367676A1 (pl) Nowe pochodne heterocykliczne i ich zastosowanie w medycynie
IL152072A0 (en) New derivatives of 1,2,3,4-tetrahydroisoquinoline, their preparation process and their use as fungicides
AU7402201A (en) Use of substituted 1-amino-5-phenylpentane-3-ol and/or 1-amino-6-phenylhexane-3-ol compounds as medicaments
HUP0100318A3 (en) Salicyli denaminoalcohol derivatives, their chiral copper complexes, their preparations and use of the latter
AU7570201A (en) Phenylethylamine derivatives and their use in the treatment of melanoma
PL359808A1 (pl) Podstawione aryloketony i ich zastosowanie jako środków chwastobójczych
HRP20020971A2 (en) 4,5-dihydro-thiazo-2-ylamine derivatives and their use as no-inhibitors
FI20001348A0 (fi) Kaasukirnu
PL351589A1 (en) Use of n-substituted heterocyclylalkylamines as herbicides and novel n-substituted thienylalkylamines
ES1044914Y (es) "bolsa perfeccionada"
HU0000068V0 (en) Modified orthesis of two parts
GB0018376D0 (en) Phenylethylamine derivatives and their use in the treatment of melanoma
GB0027574D0 (en) Phenylethylamine derivatives and their use in the treatment of melanoma
AUPQ961500A0 (en) N-containing heterocyclic compounds and their use
AU141359S (en) Bridge player's accessory
FI20011305A0 (fi) Kaasukirnu