SE8804629D0 - New therapeutically active compounds - Google Patents

New therapeutically active compounds

Info

Publication number
SE8804629D0
SE8804629D0 SE19888804629A SE8804629A SE8804629D0 SE 8804629 D0 SE8804629 D0 SE 8804629D0 SE 19888804629 A SE19888804629 A SE 19888804629A SE 8804629 A SE8804629 A SE 8804629A SE 8804629 D0 SE8804629 D0 SE 8804629D0
Authority
SE
Sweden
Prior art keywords
active compounds
therapeutically active
new therapeutically
compound
new
Prior art date
Application number
SE19888804629A
Other languages
English (en)
Swedish (sv)
Inventor
*Braendstroem A
Original Assignee
Ab Haessle
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ab Haessle filed Critical Ab Haessle
Priority to SE19888804629A priority Critical patent/SE8804629D0/xx
Publication of SE8804629D0 publication Critical patent/SE8804629D0/xx
Priority to AR89315705A priority patent/AR248136A1/es
Priority to EG62189A priority patent/EG19303A/xx
Priority to IE894048A priority patent/IE894048L/xx
Priority to EG61989A priority patent/EG19302A/xx
Priority to IE405089A priority patent/IE64199B1/en
Priority to PH39732A priority patent/PH27400A/en
Priority to GR890100833A priority patent/GR1000316B/el
Priority to IL9279989A priority patent/IL92799A/en
Priority to NZ231872A priority patent/NZ231872A/en
Priority to GR890100838A priority patent/GR1002252B/el
Priority to NZ231874A priority patent/NZ231874A/en
Priority to CA002005980A priority patent/CA2005980C/en
Priority to IL92798A priority patent/IL92798A0/xx
Priority to PH39731A priority patent/PH27446A/en
Priority to CA002005986A priority patent/CA2005986C/en
Priority to AT90901079T priority patent/ATE127799T1/de
Priority to DE68917937T priority patent/DE68917937T2/de
Priority to FI954768A priority patent/FI954768A0/fi
Priority to HU901084A priority patent/HU205926B/hu
Priority to KR1019900701827A priority patent/KR910700248A/ko
Priority to AU48175/90A priority patent/AU634741B2/en
Priority to US07/453,960 priority patent/US5025024A/en
Priority to RO147866A priority patent/RO110494B1/ro
Priority to AU48132/90A priority patent/AU639429B2/en
Priority to DE68924273T priority patent/DE68924273T2/de
Priority to JP2501536A priority patent/JP2793905B2/ja
Priority to PCT/SE1989/000740 priority patent/WO1990006925A1/en
Priority to SU894895789A priority patent/RU2073676C1/ru
Priority to ZA899795A priority patent/ZA899795B/xx
Priority to HU901095A priority patent/HUT57204A/hu
Priority to ZA899794A priority patent/ZA899794B/xx
Priority to EP90901073A priority patent/EP0449935B1/de
Priority to FI913035A priority patent/FI913035A0/fi
Priority to DD89335980A priority patent/DD296078A5/de
Priority to AT90901073T priority patent/ATE110723T1/de
Priority to PCT/SE1989/000739 priority patent/WO1990006924A1/en
Priority to US07/454,047 priority patent/US5008278A/en
Priority to JP2501537A priority patent/JP2793906B2/ja
Priority to DD89335981A priority patent/DD296079A5/de
Priority to HU901095A priority patent/HU205927B/hu
Priority to EP90901079A priority patent/EP0449940B1/de
Priority to FI913034A priority patent/FI913034A0/fi
Priority to YU242689A priority patent/YU46806B/sh
Priority to PT92649A priority patent/PT92649B/pt
Priority to PT92648A priority patent/PT92648B/pt
Priority to MYPI89001835A priority patent/MY129946A/en
Priority to CN89109589A priority patent/CN1028233C/zh
Priority to YU242789A priority patent/YU47338B/sh
Priority to CN89109587A priority patent/CN1028231C/zh
Priority to PL1989282922A priority patent/PL160767B1/pl
Priority to CS897343A priority patent/CS276361B6/cs
Priority to PL1989282923A priority patent/PL161150B1/pl
Priority to KR1019900701828A priority patent/KR910700249A/ko
Priority to US07/633,007 priority patent/US5039808A/en
Priority to BG094657A priority patent/BG60101B2/bg
Priority to BG094659A priority patent/BG60102B2/bg
Priority to NO912415A priority patent/NO178337C/no
Priority to NO912414A priority patent/NO178336C/no
Priority to DK122291A priority patent/DK170800B1/da
Priority to DK122191A priority patent/DK122191A/da
Priority to SU914895805A priority patent/RU2042673C1/ru
Priority to HR920831A priority patent/HRP920831A2/hr
Priority to LVP-93-691A priority patent/LV10267B/lv
Priority to LVP-93-860A priority patent/LV10187B/en
Priority to LTIP1726A priority patent/LT3914B/lt
Priority to LTIP1721A priority patent/LT3980B/lt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE19888804629A 1988-12-22 1988-12-22 New therapeutically active compounds SE8804629D0 (sv)

Priority Applications (67)

Application Number Priority Date Filing Date Title
SE19888804629A SE8804629D0 (sv) 1988-12-22 1988-12-22 New therapeutically active compounds
AR89315705A AR248136A1 (es) 1988-12-22 1989-12-18 Procedimiento e intermediarios para la preparacion de 5 5 5 5 5
EG62189A EG19303A (en) 1988-12-22 1989-12-18 Process for preparing of new therapeutically active compound
IE894048A IE894048L (en) 1988-12-22 1989-12-18 New therapeutically active compound and a process for its¹preparation
EG61989A EG19302A (en) 1988-12-22 1989-12-18 Compound with gastric acid inhibitory effect and process for its preparation
IE405089A IE64199B1 (en) 1988-12-22 1989-12-18 Compound with gastric acid inhibitory effect and process for its preparation
PH39732A PH27400A (en) 1988-12-22 1989-12-19 New therapeutically active compound and method of use thereof
GR890100833A GR1000316B (el) 1988-12-22 1989-12-19 Μεθοδος για την παρασκευη μιας ενωσης με γαστρικη ανασταλτικη δραση.
IL9279989A IL92799A (en) 1988-12-22 1989-12-19 Benzimidazole derivative, process for its preparation, and pharmaceutical compositions for inhibiting gastric acid secretion containing it
NZ231872A NZ231872A (en) 1988-12-22 1989-12-19 5-fluoro-2-(((4-cyclopropylmethoxy-2-pyridinyl)methyl)sulphinyl)-1h-benzimidazole, various pyridine intermediates and pharmaceutical compositions
GR890100838A GR1002252B (en) 1988-12-22 1989-12-19 A novel therapeutic active compound and preparation method therefore.
NZ231874A NZ231874A (en) 1988-12-22 1989-12-19 4-fluoro-2-(((4-methoxy-2-pyridinyl)methyl)sulphinyl)-1h-benzimidazole and pharmaceutical compositions
CA002005980A CA2005980C (en) 1988-12-22 1989-12-19 Benzimidazole derivative with gastric acid inhibitory effect and process for its preparation
IL92798A IL92798A0 (en) 1988-12-22 1989-12-19 Benzimidazole derivatives,process for their preparation and pharmaceutical compositions containing them
PH39731A PH27446A (en) 1988-12-22 1989-12-19 Compound with gastric acid inhibitory effect
CA002005986A CA2005986C (en) 1988-12-22 1989-12-19 Benzimidazole derivative with gastric acid inhibitory effect and process for its preparation
AT90901079T ATE127799T1 (de) 1988-12-22 1989-12-20 Therapeutisch aktive verbindung und verfahren zu deren herstellung.
DE68917937T DE68917937T2 (de) 1988-12-22 1989-12-20 Verbindungen mit magensäureinhibitorwirkung und verfahren zur herstellung.
FI954768A FI954768A0 (fi) 1988-12-22 1989-12-20 Välituotteina käyttökelpoiset 4-syklopropyylimetoksipyridiiniyhdisteet
HU901084A HU205926B (en) 1988-12-22 1989-12-20 Process for producing new, pharmaceutically active 5-fluoro-2- 4-/cyclopropyl-methoxy/-2-pyridinyl-methyl-sulfinyl-1h-benzimidazol and pharmaceutical compositions containing them
KR1019900701827A KR910700248A (ko) 1988-12-22 1989-12-20 위산 분비 억제 효과를 갖는 화합물 및 그의 제조 방법
AU48175/90A AU634741B2 (en) 1988-12-22 1989-12-20 Benzimidazole and (4-cyclopropyl methoxy pyridinyl) linked derivatives
US07/453,960 US5025024A (en) 1988-12-22 1989-12-20 Therapeutically active fluoro-substituted compound
RO147866A RO110494B1 (ro) 1988-12-22 1989-12-20 Compus de benzimidazol activ terapeutic, procedeu de preparare, intermediar pentru acesta si compozitie farmaceutica, continand compusul de benzimidazol
AU48132/90A AU639429B2 (en) 1988-12-22 1989-12-20 Compound with gastric acid inhibitory effect and process for its preparation
DE68924273T DE68924273T2 (de) 1988-12-22 1989-12-20 Therapeutisch aktive verbindung und verfahren zu deren herstellung.
JP2501536A JP2793905B2 (ja) 1988-12-22 1989-12-20 胃酸抑制効果を有する化合物およびその製法
PCT/SE1989/000740 WO1990006925A1 (en) 1988-12-22 1989-12-20 New therapeutically active compound and a process for its preparation
SU894895789A RU2073676C1 (ru) 1988-12-22 1989-12-20 5-фтор-2-*01([(4-циклопропилметокси-2-пиридинил)метил] сульфинил*01)-1h-бензимидазол или его физиологически приемлемая соль, фармкомпозиция на его основе и промежуточные соединения
ZA899795A ZA899795B (en) 1988-12-22 1989-12-20 Compound with gastric acid inhibitory effect and process for its preparation
HU901095A HUT57204A (en) 1988-12-22 1989-12-20 Process for producing 4-fluoro-2-///4-methoxy-2-pyridinyl/-methyl/-sulfinyl/-1h-benzimidazol with gastric acid secration-diminishing activity and pharmaceutical compositions containing them
ZA899794A ZA899794B (en) 1988-12-22 1989-12-20 New therapeutically active compound and a process for its preparation
EP90901073A EP0449935B1 (de) 1988-12-22 1989-12-20 Verbindungen mit magensäureinhibitorwirkung und verfahren zur herstellung
FI913035A FI913035A0 (fi) 1988-12-22 1989-12-20 Ny terapeutiskt aktiv foerening och foerfarande foer dess framstaellning.
DD89335980A DD296078A5 (de) 1988-12-22 1989-12-20 Verfahren zur herstellung von benzimidazolen
AT90901073T ATE110723T1 (de) 1988-12-22 1989-12-20 Verbindungen mit magensäureinhibitorwirkung und verfahren zur herstellung.
PCT/SE1989/000739 WO1990006924A1 (en) 1988-12-22 1989-12-20 Compound with gastric acid inhibitory effect and process for its preparation
US07/454,047 US5008278A (en) 1988-12-22 1989-12-20 Therapeutically active compound and a process for its preparation
JP2501537A JP2793906B2 (ja) 1988-12-22 1989-12-20 治療上活性な新規化合物およびその製法
DD89335981A DD296079A5 (de) 1988-12-22 1989-12-20 Verfahren zur herstellung von benzimidazolen
HU901095A HU205927B (en) 1988-12-22 1989-12-20 Process for producing 4-fluoro-2-///4-methoxy-2-piridinyl/-sulfinyl/-1h-benzimidazol of acid secretion inhibiting activity and pharmaceutical compositions containing them
EP90901079A EP0449940B1 (de) 1988-12-22 1989-12-20 Therapeutisch aktive verbindung und verfahren zu deren herstellung
FI913034A FI913034A0 (fi) 1988-12-22 1989-12-20 Foerening med magsyrainhiberande effekt och foerfarande foer dess framstaellning.
YU242689A YU46806B (sh) 1988-12-22 1989-12-21 5-FLUORO-2-//(4-CIKLOPROPILMETOKSI-2-PIRINIDIL)METILSULFINIL/1h-BENZIMODAZOL I POSTUPAK ZA NJEGOVO DOBIJANJE
PT92649A PT92649B (pt) 1988-12-22 1989-12-21 Processo para a preparacao do 4-fluoro-2-< { (4-metoxi-2-piridinil)-metil}-sulfinil>-1h-benzimidazol e de composicoes farmaceuticas que o contem
PT92648A PT92648B (pt) 1988-12-22 1989-12-21 Processo para a preparacao do 5-fluoro-2-< { (4-ciclopropilmetoxi-2-piridinil)-metil}-sulfinil>-1h-benzimidazol e de composicoes farmaceuticas que o contem
MYPI89001835A MY129946A (en) 1988-12-22 1989-12-21 Compound with gastric acid inhibitory effect and process for its preparation.
CN89109589A CN1028233C (zh) 1988-12-22 1989-12-21 具有抑制胃酸作用的取代的苯并咪唑的制备方法
YU242789A YU47338B (sh) 1988-12-22 1989-12-21 Novo jedinjenje 4-fluoro-2-// (4-metoksi-2-piridinil)metil-/sulfinil/- 1h-benzimidazol i postupak za njegovo dobijanje
CN89109587A CN1028231C (zh) 1988-12-22 1989-12-21 具有新治疗活性的取代的苯并咪唑的制备方法
PL1989282922A PL160767B1 (pl) 1988-12-22 1989-12-22 Sposób wytwarzania nowego 4-fluoro-2- [(4-metoksypirydynylo-2)metylosulfinylo]--1 H-benzimidazolu PL PL
CS897343A CS276361B6 (en) 1988-12-22 1989-12-22 4-fluoro-2-//(4-methoxy-2-pyridyl)methyl/sulfinyl/ -1h - benzimidazole, process for its production and a pharmaceutical comprising said compound as an active component
PL1989282923A PL161150B1 (en) 1988-12-22 1989-12-22 Method for manufacturing new 5-fluoro-2-((4-cyclopropylmethoxy-pyridinilo-2) methylsulphynyl)-1h-benzimidazole
KR1019900701828A KR910700249A (ko) 1988-12-22 1990-08-21 신규 치료학적 활성 화합물 및 그의 제조 방법
US07/633,007 US5039808A (en) 1988-12-22 1990-12-20 Therapeutically active cyclopropyl substituted compound
BG094657A BG60101B2 (bg) 1988-12-22 1991-06-19 Метод за получаване на 4-флуор-2-(((4-метокси-2- пиридинил)метил)тионил)-1н-бензимидазол
BG094659A BG60102B2 (bg) 1988-12-22 1991-06-19 Метод за получаване на 5-флуор-2(((4-циклопропил- метокси-2-пиридинил)метил)тионил)-1н-бензимидазол
NO912415A NO178337C (no) 1988-12-22 1991-06-20 Analogifremgangsmåte for fremstilling av terapeutisk aktiv 5-fluor-2[[(4-cyklopropyl-(metoksy-2-pyridinyl)metylÅsulfinylÅ-1H-benzimidazol og mellomprodukter
NO912414A NO178336C (no) 1988-12-22 1991-06-20 Analogifremgangsmåte for fremstilling av en terapeutisk aktiv benzimidazolforbindelse og mellomprodukter
DK122291A DK170800B1 (da) 1988-12-22 1991-06-21 Substitueret benzimidazolderivat og fysiologisk acceptable salte og optiske enantiomerer heraf samt fremgangsmåde til fremstilling af samme, farmaceutisk præparat indeholdende derivatet, anvendelse af derivatet til fremstilling af et lægemiddel til hæmning af mavesyresekretionen hos pattedyr og til behandling af inflammatoriske mave-tarmkanallidelser hos pattedyr samt intermediære forbindelser til
DK122191A DK122191A (da) 1988-12-22 1991-06-21 Benzimidazolderivat og fysiologisk acceptable salte heraf samt fremgangsmaade til fremstilling af samme
SU914895805A RU2042673C1 (ru) 1988-12-22 1991-06-21 4-фтор-2-{([(4-метокси -2- пиридинил) метил]сульфинил}) -1н-бензимидазол или его физиологически приемлемые соли, способ их получения, фармацевтическая композиция, 4-фтор-2-меркапто-1н- бензимидазол и 4-фтор-2-{([(4-метокси -2-пиридинил) метил]тио}) -1н-бензимидазол
HR920831A HRP920831A2 (en) 1988-12-22 1992-10-02 New therapeutically active compound and a process for the preparation eof
LVP-93-691A LV10267B (en) 1988-12-22 1993-06-28 Compound with gastric acid inhibitory effect and process for its preparation
LVP-93-860A LV10187B (en) 1988-12-22 1993-06-30 New therapeutically active compound and a process for its preparation
LTIP1726A LT3914B (en) 1988-12-22 1993-12-30 Compound with gastric acid inhibitory effect and process for its preparation
LTIP1721A LT3980B (en) 1988-12-22 1993-12-30 New therapeutically active compound and a process for its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE19888804629A SE8804629D0 (sv) 1988-12-22 1988-12-22 New therapeutically active compounds

Publications (1)

Publication Number Publication Date
SE8804629D0 true SE8804629D0 (sv) 1988-12-22

Family

ID=20374310

Family Applications (1)

Application Number Title Priority Date Filing Date
SE19888804629A SE8804629D0 (sv) 1988-12-22 1988-12-22 New therapeutically active compounds

Country Status (32)

Country Link
US (2) US5008278A (de)
EP (1) EP0449940B1 (de)
JP (1) JP2793906B2 (de)
KR (1) KR910700249A (de)
CN (1) CN1028231C (de)
AR (1) AR248136A1 (de)
AT (1) ATE127799T1 (de)
AU (1) AU634741B2 (de)
BG (1) BG60102B2 (de)
CA (1) CA2005986C (de)
DD (2) DD296079A5 (de)
DE (1) DE68924273T2 (de)
DK (1) DK170800B1 (de)
EG (1) EG19303A (de)
FI (2) FI954768A0 (de)
GR (1) GR1002252B (de)
HR (1) HRP920831A2 (de)
HU (2) HU205926B (de)
IE (1) IE894048L (de)
IL (1) IL92798A0 (de)
LT (2) LT3980B (de)
LV (1) LV10187B (de)
NZ (1) NZ231872A (de)
PH (1) PH27400A (de)
PL (1) PL161150B1 (de)
PT (1) PT92648B (de)
RO (1) RO110494B1 (de)
RU (2) RU2073676C1 (de)
SE (1) SE8804629D0 (de)
WO (1) WO1990006925A1 (de)
YU (1) YU46806B (de)
ZA (2) ZA899795B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993006097A1 (en) * 1991-09-20 1993-04-01 Merck & Co., Inc. Novel process for the preparation of anti-ulcer agents
TNSN95063A1 (fr) * 1994-05-27 1996-02-06 Astra Ab Nouveaux benzimidazoles substitues
SE9402431D0 (sv) * 1994-07-08 1994-07-08 Astra Ab New tablet formulation
DK0723436T3 (da) * 1994-07-08 2001-11-26 Astrazeneca Ab Tabletteret flerenhedsdoseringsform
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
DE19758573C2 (de) * 1997-11-26 2001-03-01 Implex Hear Tech Ag Fixationselement für ein implantierbares Mikrofon
WO1999053918A1 (en) * 1998-04-20 1999-10-28 Eisai Co., Ltd. Stabilized compositions containing benzimidazole-type compounds
SE9900274D0 (sv) * 1999-01-28 1999-01-28 Astra Ab New compound
TWI243672B (en) 1999-06-01 2005-11-21 Astrazeneca Ab New use of compounds as antibacterial agents
RU2232159C2 (ru) * 1999-07-29 2004-07-10 Регентский Совет Университета Калифорнии Производные бензимидазола и фармацевтические композиции, содержащие пролекарство ингибитора протонного насоса
AU782538B2 (en) 1999-10-20 2005-08-04 Eisai Co. Ltd. Method for stabilizing benzimidazole compounds
SE0000774D0 (sv) 2000-03-08 2000-03-08 Astrazeneca Ab New formulation
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
SE0102993D0 (sv) 2001-09-07 2001-09-07 Astrazeneca Ab New self emulsifying drug delivery system
WO2003063840A2 (en) * 2002-01-25 2003-08-07 Santarus, Inc. Transmucosal delivery of proton pump inhibitors
CA2480358A1 (en) * 2002-03-26 2003-10-09 Dr. Reddy's Laboratories Limited Crystalline forms of rabeprazole sodium
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
WO2004073654A2 (en) * 2003-02-20 2004-09-02 Santarus, Inc. A novel formulation, omeprazole antacid complex-immediate release for rapid and sustained supression of gastric acid
US8993599B2 (en) * 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
CA2531564C (en) * 2003-07-18 2016-01-19 Santarus, Inc. Pharmaceutical composition for inhibiting acid secretion
MXPA06000524A (es) * 2003-07-18 2006-08-11 Santarus Inc Formulacion farmaceutica y metodo para tratar desordenes gastrointestinales provocados por acido.
CA2540308C (en) 2003-09-26 2013-08-06 Alza Corporation Drug coating providing high drug loading and methods for providing the same
US20070292498A1 (en) * 2003-11-05 2007-12-20 Warren Hall Combinations of proton pump inhibitors, sleep aids, buffers and pain relievers
US8815916B2 (en) * 2004-05-25 2014-08-26 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8906940B2 (en) * 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
RU2325960C2 (ru) * 2005-09-22 2008-06-10 Белорусский Национальный Технический Университет Способ получения товарной продукции на литейно-прокатном комплексе металлургического мини-завода
PL2046334T3 (pl) 2006-07-25 2015-02-27 Vecta Ltd Kompozycje i sposoby hamowania wydzielania kwasów żołądkowych z wykorzystaniem pochodnych małych kwasów dikarboksylowych w połączeniu z PPI
US20090092658A1 (en) * 2007-10-05 2009-04-09 Santarus, Inc. Novel formulations of proton pump inhibitors and methods of using these formulations
US9220698B2 (en) 2008-09-09 2015-12-29 Pozen Inc. Method for delivering a pharmaceutical composition to patient in need thereof
KR20120030106A (ko) 2009-06-25 2012-03-27 아스트라제네카 아베 Ｎｓａｉｄ-연관된 궤양의 발생 위험이 있는 환자의 치료 방법
US20120294937A1 (en) 2009-12-29 2012-11-22 Novartis Ag New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080500A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
EP2601947A1 (de) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Kombinationspräparat mit fester Dosierung zur Behandlung von Erkrankungen einhergehend mit Helicobacter pylori
EP2797600A4 (de) 2011-12-28 2015-09-16 Pozen Inc Verbesserte zusammensetzungen und verfahren zur abgabe von omeprazol und acetylsalicylsäure

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US428098A (en) 1890-05-20 Electric railway
US727150A (en) 1902-06-18 1903-05-05 Peter Paul Keller Adjustable hanger for incandescent lamps.
SE418966B (sv) * 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) * 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (de) * 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) * 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) * 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) * 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
DE3215503A1 (de) 1982-04-26 1983-11-03 Zängl GmbH, 8000 München Elektrisch beheiztes schneidgeraet
SE8301182D0 (sv) * 1983-03-04 1983-03-04 Haessle Ab Novel compounds
HU195220B (en) * 1983-05-03 1988-04-28 Byk Gulden Lomberg Chem Fqb Process for production of new fluor-alkoxi-benzimidasole-derivatives and medical compositions containig them
JPS6150978A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
JPS6150979A (ja) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd ピリジン誘導体およびその製造法
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
US4738975A (en) * 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
JPS6261978A (ja) * 1985-09-12 1987-03-18 Otsuka Pharmaceut Co Ltd ５−フルオロ−１ｈ−ベンズイミダゾ−ル誘導体
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
JPS62201884A (ja) * 1986-02-28 1987-09-05 Tokyo Tanabe Co Ltd ベンズイミダゾール誘導体及びその製造法
FI90544C (fi) * 1986-11-13 1994-02-25 Eisai Co Ltd Menetelmä lääkeaineina käyttökelpoisten 2-pyridin-2-yyli-metyylitio- ja sulfinyyli-1H-bensimidatsolijohdannaisten valmistamiseksi
NZ234564A (en) * 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
FI96860C (fi) * 1987-06-17 1996-09-10 Eisai Co Ltd Analogiamenetelmä lääkeaineena käytettävän pyridiinijohdannaisen valmistamiseksi
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
DK171989B1 (da) * 1987-08-04 1997-09-08 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af 2-(2-pyridylmethylsulfinyl)-benzimidazoler
JPH0676323B2 (ja) * 1987-08-28 1994-09-28 東京田辺製薬株式会社 抗潰瘍剤

Also Published As

Publication number Publication date
LTIP1726A (en) 1995-07-25
HRP920831A2 (en) 1995-12-31
FI954768A7 (fi) 1995-10-06
PT92648A (pt) 1990-06-29
RU2073676C1 (ru) 1997-02-20
DK170800B1 (da) 1996-01-22
LV10187A (lv) 1994-10-20
CN1028231C (zh) 1995-04-19
RU2042673C1 (ru) 1995-08-27
RO110494B1 (ro) 1996-01-30
AR248136A1 (es) 1995-06-30
US5008278A (en) 1991-04-16
GR1002252B (en) 1996-04-23
FI954768L (fi) 1995-10-06
JP2793906B2 (ja) 1998-09-03
PH27400A (en) 1993-06-21
YU46806B (sh) 1994-06-10
AU634741B2 (en) 1993-03-04
ZA899794B (en) 1990-08-29
YU242689A (en) 1991-04-30
LT3914B (en) 1996-04-25
GR890100838A (el) 1991-03-15
US5039808A (en) 1991-08-13
CA2005986A1 (en) 1990-06-22
ATE127799T1 (de) 1995-09-15
FI913035A7 (fi) 1991-06-20
CA2005986C (en) 1999-08-03
WO1990006925A1 (en) 1990-06-28
FI913035A0 (fi) 1991-06-20
IE894048L (en) 1990-06-22
HUT57202A (en) 1991-11-28
HU205926B (en) 1992-07-28
PT92648B (pt) 1995-09-12
EP0449940B1 (de) 1995-09-13
LTIP1721A (en) 1995-07-25
HU901084D0 (en) 1991-09-30
DK122291A (da) 1991-06-24
LV10187B (en) 1995-04-20
ZA899795B (en) 1990-08-29
DD296078A5 (de) 1991-11-21
LT3980B (en) 1996-06-25
IL92798A0 (en) 1990-09-17
PL161150B1 (en) 1993-05-31
DK122291D0 (da) 1991-06-21
DD296079A5 (de) 1991-11-21
DE68924273T2 (de) 1996-02-15
KR910700249A (ko) 1991-03-14
BG60102B2 (bg) 1993-10-29
JPH04502461A (ja) 1992-05-07
FI954768A0 (fi) 1995-10-06
AU4817590A (en) 1990-07-10
EG19303A (en) 1994-11-30
NZ231872A (en) 1992-03-26
DE68924273D1 (de) 1995-10-19
CN1043713A (zh) 1990-07-11
HU205927B (en) 1992-07-28
EP0449940A1 (de) 1991-10-09

Similar Documents

Publication Publication Date Title
SE8804629D0 (sv) New therapeutically active compounds
FI872864A0 (fi) Menetelmä farmaseuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
KR890700125A (ko) 신규 벤즈이미다졸 유도체, 그 제조방법 및 이 화합물을 함유하는 제약 조성물
SE8300736D0 (sv) Novel pharmacologically active compounds
SE8804628D0 (sv) New compounds
FI913034A0 (fi) Foerening med magsyrainhiberande effekt och foerfarande foer dess framstaellning.
CO4940448A1 (es) Modificacion a cristal de una sustancia de medicamento
JO1679B1 (en) A new, therapeutically active compound and method for preparing it
JO1653B1 (en) The current benzimidazole is a therapeutically active method for preparing it
JO1664B1 (en) The compound has the effect of immobilizing gastric acid and the process of preparing it
SE8704049D0 (sv) Novel pharmacological compounds