TR200101343T2 - Kansere karşı kullanılan maddeler olarak alkinil-ikame edilmiş kinolin-2-on türevleri - Google Patents

Kansere karşı kullanılan maddeler olarak alkinil-ikame edilmiş kinolin-2-on türevleri

Info

Publication number
TR200101343T2
TR200101343T2 TR2001/01343T TR200101343T TR200101343T2 TR 200101343 T2 TR200101343 T2 TR 200101343T2 TR 2001/01343 T TR2001/01343 T TR 2001/01343T TR 200101343 T TR200101343 T TR 200101343T TR 200101343 T2 TR200101343 T2 TR 200101343T2
Authority
TR
Turkey
Prior art keywords
compounds
alkynyl
derivatives
agents used
against cancer
Prior art date
Application number
TR2001/01343T
Other languages
English (en)
Inventor
Deborah La Greca Susan
Peter Lyssikatos Joseph
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of TR200101343T2 publication Critical patent/TR200101343T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Bu bulus formül (I) bilesimleri ve bunun ispençiyari olarak kabul edilebilir tuzlari, ön ilaçlari ve solvatlari ile ilgilidir ki söz konusu formülde R1,R2,R3,R4,R5,R6,R7,R8,R9,R10 ve R11 burada tarif edildigi gibidir.Yukarida bahsedilen formül (I) bilesimleri memelilerde kanser gibi hiperproliferatif hastaliklarin tedavisi için kullanislidir. Bulus ayrica formül (I) bilesimlerini ihtiva eden ispençiyari müstahzarlar ve memelilerde, böyle bir tedaviye ihtiyaç duyan memeliye formül (I) bilesimleri vererek kanser de dahil anormal hücre çogalmasini önleme etme yöntemleri ile de ilgilidir.
TR2001/01343T 1998-08-27 1999-08-06 Kansere karşı kullanılan maddeler olarak alkinil-ikame edilmiş kinolin-2-on türevleri TR200101343T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9814598P 1998-08-27 1998-08-27

Publications (1)

Publication Number Publication Date
TR200101343T2 true TR200101343T2 (tr) 2001-09-21

Family

ID=22267481

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/01343T TR200101343T2 (tr) 1998-08-27 1999-08-06 Kansere karşı kullanılan maddeler olarak alkinil-ikame edilmiş kinolin-2-on türevleri

Country Status (40)

Country Link
US (3) US6150377A (tr)
EP (1) EP1107963B1 (tr)
JP (1) JP3495706B2 (tr)
KR (1) KR20010072991A (tr)
CN (1) CN1314904A (tr)
AP (1) AP2001002079A0 (tr)
AT (1) ATE321037T1 (tr)
AU (1) AU4925499A (tr)
BG (1) BG105365A (tr)
BR (1) BRPI9913138B8 (tr)
CA (2) CA2578326C (tr)
CO (1) CO5130017A1 (tr)
CZ (1) CZ2001660A3 (tr)
DE (1) DE69930518T2 (tr)
DZ (1) DZ2880A1 (tr)
EA (1) EA200100135A1 (tr)
EE (1) EE200100118A (tr)
ES (1) ES2259237T3 (tr)
GE (1) GEP20033001B (tr)
GT (1) GT199900140A (tr)
HK (1) HK1039123A1 (tr)
HR (1) HRP20010142A2 (tr)
HU (1) HUP0103228A3 (tr)
ID (1) ID27562A (tr)
IL (1) IL141239A0 (tr)
IS (1) IS5818A (tr)
MA (1) MA26680A1 (tr)
NO (1) NO20010964L (tr)
NZ (1) NZ509372A (tr)
OA (1) OA11645A (tr)
PA (1) PA8480101A1 (tr)
PE (1) PE20000986A1 (tr)
PL (1) PL346426A1 (tr)
SK (1) SK2442001A3 (tr)
SV (1) SV1999000141A (tr)
TN (1) TNSN99162A1 (tr)
TR (1) TR200101343T2 (tr)
UY (1) UY25682A1 (tr)
WO (1) WO2000012499A1 (tr)
ZA (1) ZA200101173B (tr)

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Also Published As

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US6294552B1 (en) 2001-09-25
BG105365A (en) 2001-11-30
US6579887B2 (en) 2003-06-17
EE200100118A (et) 2002-06-17
DZ2880A1 (fr) 2003-12-15
NO20010964D0 (no) 2001-02-26
CN1314904A (zh) 2001-09-26
DE69930518D1 (de) 2006-05-11
HUP0103228A2 (hu) 2002-02-28
UY25682A1 (es) 2000-03-31
CO5130017A1 (es) 2002-02-27
HRP20010142A2 (en) 2002-02-28
EP1107963A1 (en) 2001-06-20
ES2259237T3 (es) 2006-09-16
HK1039123A1 (zh) 2002-04-12
DE69930518T2 (de) 2006-09-21
AU4925499A (en) 2000-03-21
GEP20033001B (en) 2003-06-25
CA2341690A1 (en) 2000-03-09
NO20010964L (no) 2001-04-26
PA8480101A1 (es) 2003-06-30
ZA200101173B (en) 2002-04-12
NZ509372A (en) 2003-08-29
SK2442001A3 (en) 2002-10-08
AP2001002079A0 (en) 2001-03-31
BR9913138A (pt) 2001-05-08
CA2341690C (en) 2007-04-17
US6150377A (en) 2000-11-21
CA2578326A1 (en) 2000-03-09
SV1999000141A (es) 2000-07-06
ATE321037T1 (de) 2006-04-15
GT199900140A (es) 2001-02-14
PE20000986A1 (es) 2000-09-30
BR9913138B1 (pt) 2013-11-05
JP3495706B2 (ja) 2004-02-09
IS5818A (is) 2001-01-19
CA2578326C (en) 2009-11-24
WO2000012499A1 (en) 2000-03-09
CZ2001660A3 (cs) 2002-05-15
IL141239A0 (en) 2002-03-10
BRPI9913138B8 (pt) 2016-05-17
OA11645A (en) 2004-11-16
EP1107963B1 (en) 2006-03-22
MA26680A1 (fr) 2004-12-20
KR20010072991A (ko) 2001-07-31
JP2002523504A (ja) 2002-07-30
ID27562A (id) 2001-04-12
PL346426A1 (en) 2002-02-11
TNSN99162A1 (fr) 2005-11-10
US20020128287A1 (en) 2002-09-12
EA200100135A1 (ru) 2001-08-27
HUP0103228A3 (en) 2003-01-28

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