UA95464C2 - Pyridopyrazine derivatives and use thereof - Google Patents

Pyridopyrazine derivatives and use thereof

Info

Publication number
UA95464C2
UA95464C2 UAA200807895A UAA200807895A UA95464C2 UA 95464 C2 UA95464 C2 UA 95464C2 UA A200807895 A UAA200807895 A UA A200807895A UA A200807895 A UAA200807895 A UA A200807895A UA 95464 C2 UA95464 C2 UA 95464C2
Authority
UA
Ukraine
Prior art keywords
pyridopyrazine derivatives
pyridopyrazine
derivatives
mammals
enzymes
Prior art date
Application number
UAA200807895A
Other languages
English (en)
Ukrainian (uk)
Inventor
Ирена Сейпелт
Экхард КЛАУС
Экхард ГЮНТЕР
Тильманн ШУСТЕР
Михаэль ЧЕХ
Эммануэль Полимеропоулос
Original Assignee
Аэтерна Центарис Гмбх
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Аэтерна Центарис Гмбх filed Critical Аэтерна Центарис Гмбх
Publication of UA95464C2 publication Critical patent/UA95464C2/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
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    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Virology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Communicable Diseases (AREA)
  • Psychiatry (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)

Abstract

Данное изобретение касается производных пиридопиразина, которые пригодны для лечения или профилактики опосредованных или модулированных путями сигнальной трансдукции и/или ферментами физиологических и/или патофизиологических состояний у млекопитающих, в частности у человека.
UAA200807895A 2005-11-11 2006-10-11 Pyridopyrazine derivatives and use thereof UA95464C2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP05024692A EP1790342A1 (de) 2005-11-11 2005-11-11 Pyridopyrazin-Derivate und deren Verwendung als Modulatoren der Signaltransduktionswege

Publications (1)

Publication Number Publication Date
UA95464C2 true UA95464C2 (en) 2011-08-10

Family

ID=36424666

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200807895A UA95464C2 (en) 2005-11-11 2006-10-11 Pyridopyrazine derivatives and use thereof

Country Status (20)

Country Link
US (1) US8937068B2 (ru)
EP (2) EP1790342A1 (ru)
JP (1) JP5448450B2 (ru)
KR (1) KR101473662B1 (ru)
CN (1) CN101330918B (ru)
AR (1) AR056216A1 (ru)
AU (1) AU2006334721B2 (ru)
BR (1) BRPI0618451A2 (ru)
CA (1) CA2628186A1 (ru)
ES (1) ES2543962T3 (ru)
IL (1) IL191160A (ru)
NO (1) NO20082509L (ru)
NZ (1) NZ595879A (ru)
PL (1) PL1962854T3 (ru)
RU (1) RU2487713C2 (ru)
SG (1) SG10201401061XA (ru)
TW (1) TWI423973B (ru)
UA (1) UA95464C2 (ru)
WO (1) WO2007079999A2 (ru)
ZA (1) ZA200803867B (ru)

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KR20080068116A (ko) 2008-07-22
BRPI0618451A2 (pt) 2011-08-30
EP1962854B1 (de) 2015-05-06
RU2487713C2 (ru) 2013-07-20
US20070123494A1 (en) 2007-05-31
NZ595879A (en) 2013-07-26
WO2007079999A2 (de) 2007-07-19
EP1790342A1 (de) 2007-05-30
ZA200803867B (en) 2009-05-27
TWI423973B (zh) 2014-01-21
CN101330918A (zh) 2008-12-24
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US8937068B2 (en) 2015-01-20
JP2009515854A (ja) 2009-04-16
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IL191160A (en) 2016-03-31
IL191160A0 (en) 2008-12-29
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EP1962854A2 (de) 2008-09-03
JP5448450B2 (ja) 2014-03-19
CA2628186A1 (en) 2007-07-19
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AU2006334721B2 (en) 2011-08-11
PL1962854T3 (pl) 2015-10-30
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