|
US5032516A
(en)
*
|
1985-10-25 |
1991-07-16 |
Phillips Petroleum Company |
Pichia pastoris alcohol oxidase II regulatory region
|
|
US4895800A
(en)
*
|
1985-11-26 |
1990-01-23 |
Phillips Petroleum Company |
Yeast production of hepatitis B surface antigen
|
|
IL89989A0
(en)
*
|
1988-04-25 |
1989-12-15 |
Phillips Petroleum Co |
Expression of human interleukin-2 in methylotrophic yeasts
|
|
IL90021A0
(en)
*
|
1988-04-25 |
1989-12-15 |
Phillips Petroleum Co |
Process for the production of interferon
|
|
IL89993A0
(en)
*
|
1988-04-25 |
1989-12-15 |
Phillips Petroleum Co |
Expression of the hiv 24kda gag protein in methylotrophic yeasts
|
|
IL89992A0
(en)
*
|
1988-04-25 |
1989-12-15 |
Phillips Petroleum Co |
Expression of human serum albumin in methylotrophic yeasts
|
|
IL89991A0
(en)
*
|
1988-04-25 |
1989-12-15 |
Phillips Petroleum Co |
Expression of hepatitis b pres2 protein in methylotrophic yeasts
|
|
AT390267B
(de)
*
|
1988-06-08 |
1990-04-10 |
Vogelbusch Gmbh |
Verfahren zum markieren und identifizieren von industriell eingesetzten mikroorganismen, vorzugsweise hefestaemmen
|
|
US5102789A
(en)
*
|
1989-03-15 |
1992-04-07 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Production of epideramal growth factor in pichia pastoris yeast cells
|
|
US5204252A
(en)
*
|
1989-02-08 |
1993-04-20 |
Henkel Research Corporation |
Candida tropicalis transformation system
|
|
DD297841A5
(de)
*
|
1989-02-13 |
1992-01-23 |
The Salk Institute Biotechnology/Industrial Associates,Us |
Herstellung von superoxiddismutase in pichia pastoris hefezellen
|
|
JPH0669365B2
(ja)
*
|
1989-05-22 |
1994-09-07 |
株式会社ミドリ十字 |
アルブミン遺伝子を含むプラスミド、形質転換体、形質転換体の製造方法、アルブミンの製造方法
|
|
CA2017176A1
(en)
*
|
1989-05-22 |
1990-11-22 |
Yoshitomi Pharmaceutical Industries Ltd. |
Albumin gene-containing plasmid, transformant carrying same, production of such transformant and production of albumin
|
|
US6440681B1
(en)
|
1990-04-03 |
2002-08-27 |
Merck & Co., Inc. |
Methods for identifying agonists and antagonists for human neuronal nicotinic acetylcholine receptors
|
|
US5369028A
(en)
*
|
1990-04-03 |
1994-11-29 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
DNA and mRNA encoding human neuronal nicotinic acetylcholine receptor compositions and cells transformed with same
|
|
US5258302A
(en)
*
|
1990-07-03 |
1993-11-02 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
DNA for expression of aprotinin in methylotrophic yeast cells
|
|
EP0548267A4
(en)
*
|
1990-09-04 |
1994-11-23 |
Salk Inst Biotech Ind |
Production of insulin-like growth factor-1 in methylotrophic yeast cells
|
|
US5612198A
(en)
*
|
1990-09-04 |
1997-03-18 |
The Salk Institute |
Production of insulin-like growth factor-1 in methylotrophic yeast cells
|
|
US5268273A
(en)
*
|
1990-12-14 |
1993-12-07 |
Phillips Petroleum Company |
Pichia pastoris acid phosphatase gene, gene regions, signal sequence and expression vectors comprising same
|
|
WO1992013951A1
(en)
*
|
1991-02-04 |
1992-08-20 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Production of human serum albumin in methylotrophic yeast cells
|
|
CA2063890C
(en)
*
|
1991-03-27 |
2007-03-13 |
Masami Miura |
Mutant aox2 promoter, microorganism carrying same, method of preparation thereof and production of heterologous protein using such microorganism
|
|
ATE220105T1
(de)
*
|
1991-04-01 |
2002-07-15 |
Merck & Co Inc |
Gene, die die proteolytische aktivitaet von pichia beeinflussen und deren verwendung
|
|
CA2058820C
(en)
*
|
1991-04-25 |
2003-07-15 |
Kotikanyad Sreekrishna |
Expression cassettes and vectors for the secretion of human serum albumin in pichia pastoris cells
|
|
US5330901A
(en)
*
|
1991-04-26 |
1994-07-19 |
Research Corporation Technologies, Inc. |
Expression of human serum albumin in Pichia pastoris
|
|
US5665600A
(en)
*
|
1991-09-18 |
1997-09-09 |
Research Corporation Technologies, Inc. |
Pichia pastoris linear plasmids and DNA fragments thereof
|
|
CZ225795A3
(en)
*
|
1993-03-03 |
1996-02-14 |
Du Pont |
Enzymatically active glycolate oxidase, process for preparing thereof, transformed methylotropic yeast, nucleic acid sequence and plasmid
|
|
CA2155330C
(en)
|
1993-03-08 |
2002-01-29 |
Kathryn J. Elliott |
Human neuronal nicotinic acetylcholine receptor compositions and methods employing same
|
|
US5849895A
(en)
|
1993-04-20 |
1998-12-15 |
Sibia Neurosciences, Inc. |
Human N-methyl-D-aspartate receptor subunits, nucleic acids encoding same and uses therefor
|
|
HUT73395A
(en)
*
|
1993-05-28 |
1996-07-29 |
Du Pont |
Process for preparing glyoxylic acid/dialkyl aminomethylphosphonate mixtures
|
|
US5521297A
(en)
|
1993-06-04 |
1996-05-28 |
Salk Institute Biotechnology/Industrial Associates |
Nucleic acids encoding human metabotropic glutamate receptors
|
|
US5912122A
(en)
|
1993-06-04 |
1999-06-15 |
Sibia Neurosciences, Inc. |
Nucleic acids encoding and method for detecting nucleic acid encoding human metabotropic glutamate receptor subtype mGluR6
|
|
US6001581A
(en)
|
1993-06-04 |
1999-12-14 |
Sibia Neurosciences, Inc. |
Cation-based bioassay using human metabotropic glutamate receptors
|
|
US6638905B2
(en)
*
|
1993-06-18 |
2003-10-28 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CFR receptor(s)
|
|
US6495343B1
(en)
|
1993-06-18 |
2002-12-17 |
The Salk Institute For Biological Studies |
Cloning and recombinant production of CRF receptor(s)
|
|
WO1995013299A1
(en)
*
|
1993-11-08 |
1995-05-18 |
The Salk Institute Biotechnology/Industrial Associates, Inc. |
Human neuronal nicotinic acetylcholine receptor compositions and methods employing same
|
|
EP0733059B1
(de)
*
|
1993-12-09 |
2000-09-13 |
Thomas Jefferson University |
Verbindungen und verfahren zur ortsspezifischen mutation in eukaryotischen zellen
|
|
US5866543A
(en)
*
|
1995-06-05 |
1999-02-02 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
US5945275A
(en)
*
|
1994-10-18 |
1999-08-31 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
AU711405B2
(en)
*
|
1994-10-18 |
1999-10-14 |
Dendreon Corporation |
Nematode-extracted serine protease inhibitors and anticoagulant proteins
|
|
US5863894A
(en)
*
|
1995-06-05 |
1999-01-26 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
US5866542A
(en)
*
|
1994-10-18 |
1999-02-02 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
US5872098A
(en)
*
|
1995-06-05 |
1999-02-16 |
Corvas International, Inc. |
Nematode-extracted anticoagulant protein
|
|
CA2202351A1
(en)
*
|
1994-10-18 |
1996-04-25 |
George Phillip Vlasuk |
Nematode-extracted serine protease inhibitors and anticoagulant proteins
|
|
EP0815209B2
(de)
|
1995-03-17 |
2015-02-25 |
Novozymes A/S |
Neue endoglukanase
|
|
US6485967B1
(en)
|
1995-06-07 |
2002-11-26 |
Merck & Co., Inc. |
Human neuronal nicotinic acetylcholine receptor α6 and β3 nucleic acid
|
|
WO1997014786A1
(en)
*
|
1995-10-18 |
1997-04-24 |
New York Blood Center, Inc. |
RECOMBINANT α-N-ACETYLGALACTOSAMINIDASE ENZYME
|
|
US6001597A
(en)
*
|
1995-11-09 |
1999-12-14 |
Zymogenetics, Inc. |
Compositions and methods for producing heterologous polypeptides in Pichia methanolica
|
|
JP2000500014A
(ja)
*
|
1995-11-09 |
2000-01-11 |
ザイモジェネティクス,インコーポレイティド |
ピヒア・メタノリカ中で異種ポリペプチドを生産するための組成物と方法
|
|
DE69717092T2
(de)
|
1996-03-01 |
2003-07-24 |
Novo Nordisk A/S, Bagsvaerd |
Gebrauch einer pharmazeutischen Zusammensetzung, enthaltend ein appetitzügelndes Peptid
|
|
US5731181A
(en)
*
|
1996-06-17 |
1998-03-24 |
Thomas Jefferson University |
Chimeric mutational vectors having non-natural nucleotides
|
|
UA75316C2
(uk)
|
1996-10-16 |
2006-04-17 |
Займодженетікс, Інк. |
Гомологи з фактором росту фібробласта
|
|
MX9605082A
(es)
|
1996-10-24 |
1998-04-30 |
Univ Autonoma De Nuevo Leon |
Levaduras metilotroficas modificadas geneticamente para la produccion y secrecion de hormona de crecimiento humano.
|
|
IL142164A0
(en)
|
1998-09-23 |
2002-03-10 |
Zymogenetics Inc |
Cytokine receptor zalpha11
|
|
AU764039B2
(en)
|
1998-12-07 |
2003-08-07 |
Zymogenetics Inc. |
Growth factor homolog ZVEGF3
|
|
US6780615B1
(en)
|
1998-12-31 |
2004-08-24 |
Genway Biotech Inc. |
Production of recombinant monellin using methylotrophic yeast expression system
|
|
US7833529B1
(en)
|
1999-01-07 |
2010-11-16 |
Zymogenetics, Inc. |
Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
|
|
DE60043626D1
(de)
|
1999-01-07 |
2010-02-11 |
Zymogenetics Inc |
Verfahren zur therapeutischen Verwendung von löslichen rezeptoren BR43X2
|
|
EP1881070B1
(de)
|
1999-03-09 |
2012-10-03 |
Zymogenetics, Inc. |
Menschliche Zytokine als Liganden des Z-Alpha-Rezeptors und Verwendungen davon
|
|
US7504253B2
(en)
*
|
1999-06-11 |
2009-03-17 |
The Burnham Institute For Medical Research |
Nucleic acid encoding proteins involved in protein degradation, products and methods related thereof
|
|
CA2378519C
(en)
|
1999-07-07 |
2011-01-25 |
Zymogenetics, Inc. |
Human cytokine receptor
|
|
DE60043944D1
(de)
|
1999-12-23 |
2010-04-15 |
Zymogenetics Inc |
Zytokin zcyt018
|
|
ATE473280T1
(de)
|
2000-05-11 |
2010-07-15 |
Zymogenetics Inc |
Zsig33-ähnliche peptide
|
|
CA2412239C
(en)
|
2000-06-26 |
2013-05-28 |
Zymogenetics, Inc. |
Cytokine receptor zcytor17
|
|
US7863020B2
(en)
|
2000-06-28 |
2011-01-04 |
Glycofi, Inc. |
Production of sialylated N-glycans in lower eukaryotes
|
|
US7598055B2
(en)
*
|
2000-06-28 |
2009-10-06 |
Glycofi, Inc. |
N-acetylglucosaminyltransferase III expression in lower eukaryotes
|
|
US8697394B2
(en)
*
|
2000-06-28 |
2014-04-15 |
Glycofi, Inc. |
Production of modified glycoproteins having multiple antennary structures
|
|
EP2322644A1
(de)
|
2000-06-28 |
2011-05-18 |
GlycoFi, Inc. |
Verfahren für die Herstellung modifizierter Glykoproteine
|
|
US7625756B2
(en)
|
2000-06-28 |
2009-12-01 |
GycoFi, Inc. |
Expression of class 2 mannosidase and class III mannosidase in lower eukaryotic cells
|
|
US7449308B2
(en)
|
2000-06-28 |
2008-11-11 |
Glycofi, Inc. |
Combinatorial DNA library for producing modified N-glycans in lower eukaryotes
|
|
US6927040B2
(en)
|
2000-06-30 |
2005-08-09 |
Zymogenetics, Inc. |
Interferon-like protein Zcyto21
|
|
EP2267135A3
(de)
|
2000-06-30 |
2011-09-14 |
Vib Vzw |
Modifikation der Proteinglycosylierung in Pichia Pastoris
|
|
US7009045B2
(en)
*
|
2000-07-14 |
2006-03-07 |
Archer-Daniels-Midland Company |
Transformation systems for flavinogenic yeast
|
|
EP1736545A3
(de)
|
2000-08-08 |
2007-03-28 |
ZymoGenetics, Inc. |
Lösliche Zcyctor 11 Cytokinrezeptoren
|
|
US20030012783A1
(en)
|
2001-02-20 |
2003-01-16 |
Wayne Kindsvogel |
Antibodies that bind both BCMA and TACI
|
|
MXPA03008590A
(es)
|
2001-03-22 |
2003-12-08 |
Novo Nordisk Healthcare Ag |
Derivados del factor vii de coagulacion.
|
|
US6699691B2
(en)
|
2001-04-05 |
2004-03-02 |
The Board Of Regents Of The University Of Nebraska |
Alcohol oxidase 1 regulatory nucleotide sequences for heterologous gene expression in yeast
|
|
BRPI0209933B8
(pt)
|
2001-05-24 |
2021-05-25 |
Zymogenetics Inc |
proteína de fusão, e, molécula de ácido nucleico
|
|
DK1451322T3
(da)
|
2001-11-05 |
2010-02-01 |
Zymogenetics Inc |
Il-21-antagonister
|
|
US7087418B2
(en)
*
|
2001-12-19 |
2006-08-08 |
Bristol-Myers Squibb Company |
Pichia pastoris formate dehydrogenase and uses therefor
|
|
ATE401390T1
(de)
|
2002-01-18 |
2008-08-15 |
Zymogenetics Inc |
Zytokin (zcytor17-ligand)
|
|
AU2003280410B8
(en)
|
2002-01-18 |
2009-04-23 |
Zymogenetics, Inc. |
Cytokine receptor zcytor17 multimers
|
|
US20060088834A1
(en)
*
|
2002-04-15 |
2006-04-27 |
Gretchen Bain |
Matrix analysis of gene expression in cells (magec)
|
|
EP2295455A1
(de)
|
2002-04-19 |
2011-03-16 |
ZymoGenetics, L.L.C. |
Cytokinrezeptor
|
|
IL165717A0
(en)
|
2002-06-26 |
2006-01-15 |
Flanders Interuniversity Inst |
A strain of methylotrophic yeast for producing proteins
|
|
ATE494367T1
(de)
*
|
2002-12-18 |
2011-01-15 |
Hoffmann La Roche |
Rekombinante desoxyribonuclease i aus rinder- pankreas mit hoher spezifischer aktivität
|
|
DE60319333D1
(de)
*
|
2002-12-20 |
2008-04-10 |
Roche Diagnostics Gmbh |
Hitzelabile Desoxyribonuklease I-Varianten
|
|
US7332299B2
(en)
*
|
2003-02-20 |
2008-02-19 |
Glycofi, Inc. |
Endomannosidases in the modification of glycoproteins in eukaryotes
|
|
EP1460425A1
(de)
*
|
2003-03-17 |
2004-09-22 |
Boehringer Mannheim Gmbh |
Entglykosilierte Enzymen für Konjugaten
|
|
EP1927600A1
(de)
|
2003-08-07 |
2008-06-04 |
Zymogenetics, Inc. |
Homogene Präparate von IL-28 und IL-29
|
|
ES2381110T3
(es)
|
2003-09-09 |
2012-05-23 |
Novo Nordisk Health Care Ag |
Polipéptidos de factor VII de coagulación
|
|
ATE455849T1
(de)
*
|
2003-12-05 |
2010-02-15 |
Hoffmann La Roche |
Rekombinante carboxypeptidase b und ihre aufreinigung
|
|
US20070281332A1
(en)
|
2004-02-13 |
2007-12-06 |
Allan Svendsen |
Protease Variants
|
|
ATE517914T1
(de)
|
2004-03-08 |
2011-08-15 |
Zymogenetics Inc |
Dimere fusionsproteine und materialien und verfahren zu deren herstellung
|
|
CA2574564C
(en)
|
2004-07-29 |
2013-04-16 |
Zymogenetics, Inc. |
Use of il-28 and il-29 to treat cancer and autoimmune disorders
|
|
CN101001951B
(zh)
|
2004-08-02 |
2011-06-15 |
巴斯福植物科学有限公司 |
分离转录终止序列的方法
|
|
EP2192132A3
(de)
|
2005-02-08 |
2010-08-18 |
ZymoGenetics, Inc. |
Anti-il-20-, Anti-il-22- und Anti-il-22ra-Antikörper und Bindungspartner sowie Verwendungsverfahren bei Entzündungen
|
|
AU2006237329B2
(en)
|
2005-04-18 |
2012-04-12 |
Novo Nordisk A/S |
IL-21 variants
|
|
EP3214095B1
(de)
|
2005-05-12 |
2019-12-11 |
ZymoGenetics, Inc. |
Zusammensetzungen und verfahren zur modulation von immunsystemreaktionen
|
|
US7393667B2
(en)
*
|
2005-05-31 |
2008-07-01 |
Bristol-Myers Squibb Company |
Stereoselective reduction process for the preparation of pyrrolotriazine compounds
|
|
AU2006278229B2
(en)
*
|
2005-08-09 |
2011-10-27 |
Ares Trading S.A. |
Methods for treating B-cell malignancies using TACI-Ig fusion molecule
|
|
EP1922079A2
(de)
|
2005-08-09 |
2008-05-21 |
ZymoGenetics, Inc. |
Verfahren zur behandlung und prävention abnormaler zellproliferation mittels taci-fusionsmolekülen
|
|
CN102660614A
(zh)
|
2005-08-16 |
2012-09-12 |
诺沃-诺迪斯克有限公司 |
制备成熟胰岛素多肽的方法
|
|
JP5690047B2
(ja)
|
2005-09-14 |
2015-03-25 |
ノボ ノルディスク ヘルス ケア アーゲー |
ヒト凝固第vii因子ポリペプチド
|
|
CA2621344C
(en)
*
|
2005-09-14 |
2014-12-16 |
Sanofi-Aventis Deutschland Gmbh |
Cleavage of precursors of insulins by a variant of trypsin
|
|
US7855279B2
(en)
|
2005-09-27 |
2010-12-21 |
Amunix Operating, Inc. |
Unstructured recombinant polymers and uses thereof
|
|
EA015351B1
(ru)
|
2005-09-28 |
2011-06-30 |
Займодженетикс, Инк. |
Антагонисты il-17a и il-17f и способы их применения
|
|
JP2009537563A
(ja)
*
|
2006-05-15 |
2009-10-29 |
アレス トレーディング ソシエテ アノニム |
Taci融合分子を使用する自己免疫疾患を治療するための方法
|
|
EP2069502B1
(de)
|
2006-09-27 |
2014-02-26 |
Novo Nordisk A/S |
Verfahren zur herstellung gereifter insulinpolypeptide
|
|
WO2008120107A2
(en)
|
2007-04-03 |
2008-10-09 |
Oxyrane (Uk) Limited |
Glycosylation of molecules
|
|
US20100240597A1
(en)
|
2007-06-15 |
2010-09-23 |
Arkansas State University |
Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same
|
|
KR101700711B1
(ko)
|
2007-11-21 |
2017-01-31 |
로스킬드 유니베르시테트 |
얼음-결합 활성을 포함하는 폴리펩티드
|
|
CN101952309A
(zh)
*
|
2007-12-21 |
2011-01-19 |
Ifxa有限公司 |
蛋白酶抑制剂
|
|
AU2009207645B2
(en)
*
|
2008-01-25 |
2014-11-13 |
Aarhus Universitet |
Selective exosite inhibition of PAPP-A activity against IGFBP-4
|
|
JP5647009B2
(ja)
*
|
2008-03-03 |
2014-12-24 |
アッヴィ・インコーポレイテッド |
酵母を形質転換するための方法
|
|
WO2009120922A2
(en)
|
2008-03-27 |
2009-10-01 |
Zymogenetics, Inc. |
Compositions and methods for inhibiting pdgfrbeta and vegf-a
|
|
WO2009139349A1
(ja)
*
|
2008-05-14 |
2009-11-19 |
Bio-energy株式会社 |
酵母細胞に遺伝子を導入する方法およびそのためのベクター
|
|
JP2011526154A
(ja)
|
2008-06-27 |
2011-10-06 |
ザイモジェネティクス, インコーポレイテッド |
可溶性ハイブリッドFcγレセプターおよび関連する方法
|
|
US20110275535A1
(en)
|
2008-12-16 |
2011-11-10 |
Novartis Ag |
Yeast Display Systems
|
|
CA2748314C
(en)
|
2009-02-03 |
2018-10-02 |
Amunix Operating Inc. |
Extended recombinant polypeptides and compositions comprising same
|
|
EP2406282A1
(de)
|
2009-03-11 |
2012-01-18 |
Novo Nordisk A/S |
Interleukin-21-varianten mit antagonistischer bindung an den il-21-rezeptor
|
|
US20120282285A1
(en)
|
2009-07-17 |
2012-11-08 |
Rigshospitalet |
Masp isoforms as inhibitors of complement activation
|
|
AU2010290131C1
(en)
|
2009-08-24 |
2015-12-03 |
Amunix Operating Inc. |
Coagulation factor VII compositions and methods of making and using same
|
|
US9598682B2
(en)
|
2009-09-29 |
2017-03-21 |
Vib Vzw |
Hydrolysis of mannose-1-phospho-6-mannose linkage to phospho-6-mannose
|
|
US20130053550A1
(en)
|
2009-11-19 |
2013-02-28 |
Oxyrane Uk Limited |
Yeast strains producing mammalian-like complex n-glycans
|
|
US8815541B2
(en)
|
2009-11-25 |
2014-08-26 |
Novo Nordisk A/S |
Method for making polypeptides
|
|
ES2583259T3
(es)
|
2009-12-01 |
2016-09-20 |
Novo Nordisk A/S |
Nuevas liasas alfa-amidantes de peptidil alfa-hidroxiglicina
|
|
CA2791841C
(en)
|
2010-03-05 |
2023-01-03 |
Rigshospitalet |
Chimeric inhibitor molecules of complement activation
|
|
US8822642B2
(en)
|
2010-06-09 |
2014-09-02 |
Zymogenetics, Inc. |
Dimeric fusion proteins and related compositions and methods
|
|
WO2012042387A2
(en)
|
2010-09-29 |
2012-04-05 |
Oxyrane Uk Limited |
De-mannosylation of phosphorylated n-glycans
|
|
US9347050B2
(en)
|
2010-09-29 |
2016-05-24 |
Oxyrane Uk Limited |
Mannosidases capable of uncapping mannose-1-phospho-6-mannose linkages and demannosylating phosphorylated N-glycans and methods of facilitating mammalian cellular uptake of glycoproteins
|
|
BR112014015933A2
(pt)
|
2011-12-30 |
2019-09-24 |
Oxyrane Uk Ltd |
métodos e materiais para reduzir a degradação das proteínas recombinantes
|
|
SG10201606285YA
(en)
|
2012-02-01 |
2016-09-29 |
Synthetic Genomics Inc |
Materials and methods for the synthesis of error-minimized nucleic acid molecules
|
|
AU2013217986B2
(en)
|
2012-02-09 |
2017-04-27 |
Var2 Pharmaceuticals Aps |
Targeting of chondroitin sulfate glycans
|
|
BR112014020694A2
(pt)
|
2012-02-15 |
2018-05-08 |
Amunix Operating Inc. |
proteína de fusão do fator viii compreendendo polipeptídeo do fator viii fusionado a polipeptí-deo recombinante estendido (xten) e seu método de fabricação, ácido nucleico, vetores, célula hospedeira, bem como composição farmacêutica e seu uso no tratamento de coagulopatia, episódio de hemorragia e hemofilia a
|
|
CA2864126A1
(en)
|
2012-02-15 |
2013-08-22 |
Biogen Idec Ma Inc. |
Recombinant factor viii proteins
|
|
EP3628326B1
(de)
|
2012-03-15 |
2024-02-28 |
Oxyrane UK Limited |
Verfahren und materialien zur behandlung von morbus pompe
|
|
KR101958234B1
(ko)
*
|
2012-05-09 |
2019-03-14 |
엘지이노텍 주식회사 |
보이스 코일 모터
|
|
CN104704118A
(zh)
|
2012-10-15 |
2015-06-10 |
诺和诺德保健Ag(股份有限公司) |
凝血因子vii多肽
|
|
US20190040368A1
(en)
|
2013-03-05 |
2019-02-07 |
Oxyrane Uk Limited |
Production of catalytically active type i sulfatase
|
|
EP2976352B1
(de)
|
2013-03-21 |
2021-08-18 |
Evonik Operations GmbH |
Reinigung von tripelhelikalen proteinen
|
|
JP2016521701A
(ja)
|
2013-06-07 |
2016-07-25 |
ノヴォ ノルディスク アー/エス |
成熟インスリンポリペプチドを作製するための方法
|
|
WO2014202089A2
(en)
|
2013-06-18 |
2014-12-24 |
Roskilde Universitet |
Variants of anti-freeze polypeptides
|
|
US10548953B2
(en)
|
2013-08-14 |
2020-02-04 |
Bioverativ Therapeutics Inc. |
Factor VIII-XTEN fusions and uses thereof
|
|
AU2014317807B2
(en)
|
2013-09-09 |
2019-02-21 |
Evonik Operations Gmbh |
Modified bacterial collagen-like proteins
|
|
ES2897639T3
(es)
*
|
2014-07-30 |
2022-03-02 |
Daiichi Sankyo Co Ltd |
Método para la producción secretora de alto nivel mejorada de proteínas
|
|
BR112018002150A2
(pt)
|
2015-08-03 |
2018-09-18 |
Bioverativ Therapeutics Inc |
proteínas de fusão do fator ix e métodos de fabricação e uso das mesmas
|
|
WO2017044424A1
(en)
|
2015-09-08 |
2017-03-16 |
Theripion, Inc. |
Apoa-1 fusion polypeptides and related compositions and methods
|
|
EP3352760B1
(de)
|
2015-09-21 |
2026-03-11 |
Aptevo Research and Development LLC |
Cd3-bindende polypeptide
|
|
IL319473A
(en)
|
2016-12-02 |
2025-05-01 |
Bioverativ Therapeutics Inc |
Methods for treating hemophilic arthritis using chimeric blood clotting factors
|
|
WO2018136163A2
(en)
|
2016-12-09 |
2018-07-26 |
Theripion, Inc. |
Tandem apoa-1 fusion polypeptides
|
|
EP3556856A4
(de)
*
|
2016-12-15 |
2020-06-24 |
Kaneka Corporation |
Neuartige wirtszelle und herstellungsverfahren für zielprotein unter verwendung davon
|
|
SG11202000503QA
(en)
|
2017-07-20 |
2020-02-27 |
Aptevo Res & Development Llc |
Antigen binding proteins binding to 5t4 and 4-1bb and related compositions and methods
|
|
BR112020012364A2
(pt)
|
2017-12-20 |
2020-11-24 |
Harbour Biomed (Shanghai) Co., Ltd |
anticorpos de ligação a ctla-4 e usos dos mesmos
|
|
US10150801B1
(en)
|
2017-12-27 |
2018-12-11 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
EP3732190B1
(de)
|
2017-12-27 |
2025-08-06 |
Imunami Laboratories Pte. Ltd. |
Rekombinante polypeptide und verfahren zur verwendung davon
|
|
DE202019005554U1
(de)
*
|
2018-03-06 |
2021-01-18 |
Joywell Foods, Inc. |
Rekombinant exprimierte geschmacksmodifizierende Polypeptide und Präparate und Formulierungen, die diese enthalten
|
|
BR112020022164A2
(pt)
|
2018-05-18 |
2021-02-02 |
Bioverativ Therapeutics Inc. |
métodos de tratamento de hemofilia a
|
|
US20210278406A1
(en)
|
2018-07-13 |
2021-09-09 |
Varct Diagnostic Aps |
Isolation of circulating cells of fetal origin using recombinant malaria protein var2csa
|
|
CN111378585B
(zh)
|
2018-12-28 |
2023-06-16 |
丰益(上海)生物技术研发中心有限公司 |
用于表达外源基因的毕赤酵母突变株
|
|
AU2020252241B2
(en)
*
|
2019-04-01 |
2024-03-21 |
Universität Für Bodenkultur Wien |
Mut- methylotrophic yeast
|
|
WO2021040610A1
(en)
|
2019-08-26 |
2021-03-04 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
US10675332B1
(en)
|
2019-08-26 |
2020-06-09 |
Imunami Laboratories Pte. Ltd. |
Recombinant polypeptides and methods of use thereof
|
|
EP4168034B1
(de)
|
2020-06-22 |
2025-11-26 |
Imunami Laboratories Pte. Ltd. |
Rekombinantes alpha-a-crystallin und kombinationen zur verwendung bei der behandlung von krebs
|
|
US12180521B2
(en)
|
2021-02-19 |
2024-12-31 |
Theripion, Inc. |
Paraoxonase fusion polypeptides and related compositions and methods
|
|
CN120584137A
(zh)
|
2023-01-06 |
2025-09-02 |
阿帕特夫研究和发展有限公司 |
双特异性pd-l1和cd40结合分子以及其用途
|
|
WO2024259220A1
(en)
|
2023-06-15 |
2024-12-19 |
Theripion, Inc. |
Pon3 and evolved pon1 fusion polypeptides
|