ZA953358B - New pharmaceutical composition based on taxoids - Google Patents

New pharmaceutical composition based on taxoids

Info

Publication number: ZA953358B
Authority: ZA; South Africa
Prior art keywords: pharmaceutical composition; taxoids; composition based; new pharmaceutical; docetaxel
Prior art date: 1994-04-25

Application number

ZA953358A

Other languages

English (en)

Inventor

Manfred Duerr

Joerg-Christain Hager

Armin Wendel

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-25

Filing date

1995-04-25

Publication date

1996-01-17

1995-04-25 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1996-01-17 Publication of ZA953358B publication Critical patent/ZA953358B/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title abstract 2
ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 2
229960003668 docetaxel Drugs 0.000 abstract 2
150000003904 phospholipids Chemical class 0.000 abstract 2
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Oil, Petroleum & Natural Gas (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Biophysics (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Medicinal Preparation (AREA)

ZA953358A 1994-04-25 1995-04-25 New pharmaceutical composition based on taxoids ZA953358B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR9404951A FR2718963B1 (fr)	1994-04-25	1994-04-25	Nouvelle composition pharmaceutique à base de taxoïdes.

Publications (1)

Publication Number	Publication Date
ZA953358B true ZA953358B (en)	1996-01-17

Family

ID=9462475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA953358A ZA953358B (en)	1994-04-25	1995-04-25	New pharmaceutical composition based on taxoids

Country Status (26)

Country	Link
US (1)	US5670536A (de)
EP (1)	EP0758231B1 (de)
JP (1)	JP3950993B2 (de)
KR (1)	KR100401119B1 (de)
CN (1)	CN1283243C (de)
AT (1)	ATE202931T1 (de)
AU (1)	AU691283B2 (de)
BR (1)	BR9507846A (de)
CZ (1)	CZ285720B6 (de)
DE (1)	DE69521693T2 (de)
DK (1)	DK0758231T3 (de)
ES (1)	ES2160163T3 (de)
FI (1)	FI118204B (de)
FR (1)	FR2718963B1 (de)
GE (1)	GEP20002069B (de)
GR (1)	GR3036211T3 (de)
HU (1)	HU225971B1 (de)
NO (1)	NO314745B1 (de)
NZ (1)	NZ285122A (de)
PL (1)	PL179623B1 (de)
PT (1)	PT758231E (de)
RU (1)	RU2157200C2 (de)
SK (1)	SK283255B6 (de)
TW (1)	TW416849B (de)
WO (1)	WO1995028923A1 (de)
ZA (1)	ZA953358B (de)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2698871B1 (fr)	1992-12-09	1995-02-24	Rhone Poulenc Rorer Sa	Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US6096331A (en) *	1993-02-22	2000-08-01	Vivorx Pharmaceuticals, Inc.	Methods and compositions useful for administration of chemotherapeutic agents
US5439686A (en) *	1993-02-22	1995-08-08	Vivorx Pharmaceuticals, Inc.	Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US6395770B1 (en)	1995-10-26	2002-05-28	Baker Norton Pharmaceuticals, Inc.	Method and compositions for administering taxanes orally to human patients
US6245805B1 (en)	1995-10-26	2001-06-12	Baker Norton Pharmaceuticals, Inc.	Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
BRPI9810945B8 (pt) *	1997-06-27	2021-05-25	Abraxis Bioscience Inc	formulações de agentes farmacológicos, métodos para sua preparação e métodos para uso das mesmas
US8853260B2 (en)	1997-06-27	2014-10-07	Abraxis Bioscience, Llc	Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
SK287775B6 (sk) *	1998-02-05	2011-09-05	Novartis Ag	Farmaceutická formulácia obsahujúca epothilon, infúzny roztok a použitie farmaceutickej formulácie
US6071952A (en) *	1998-12-02	2000-06-06	Mylan Pharmaceuticals, Inc.	Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
GB9920548D0 (en) *	1999-08-31	1999-11-03	Rhone Poulenc Rorer Sa	Treatment of hepatocellular carcinoma
RU2213746C1 (ru) *	2002-02-15	2003-10-10	Научно-исследовательский институт физико-химической медицины	Компонент, обеспечивающий поверхностно-активные свойства композиций - аналогов препаратов для заместительной сурфактантной терапии легочных заболеваний
DE10255285A1 (de) *	2002-11-26	2004-06-03	Mcs Micro Carrier Systems Gmbh	Selbst formende Phospholipid-Gele
US20050152979A1 (en) *	2003-09-05	2005-07-14	Cell Therapeutics, Inc.	Hydrophobic drug compositions containing reconstitution enhancer
US8557861B2 (en) *	2004-09-28	2013-10-15	Mast Therapeutics, Inc.	Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US7446126B2 (en) *	2004-10-08	2008-11-04	Indena S.P.A.	Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
TWI376239B (en) *	2006-02-01	2012-11-11	Andrew Xian Chen	Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
JP2010524919A (ja) *	2007-04-23	2010-07-22	サン、ファーマスーティカル、インダストリーズ、リミテッド	医薬組成物
EP1987813A1 (de) *	2007-05-04	2008-11-05	Pharmatex Italia Srl	Injizierbare pharmazeutische Formulierung aus Taxoiden in stabilen Liposomen
RU2370261C2 (ru) *	2007-08-03	2009-10-20	Закрытое Акционерное Общество "Биокад"	Стабильная эмульсия для парентерального введения плохо растворимых в воде соединений, обладающих противоопухолевой активностью, и способ ее получения
EP2205215A2 (de) *	2007-10-01	2010-07-14	Intas Pharmaceuticals Limited	Absolut ethanolfreie injizierbare docetaxelzusammensetzung
CN101971189A (zh) *	2007-11-07	2011-02-09	爱墨菲特有限公司	压痕泡沫数字扫描仪
RU2370258C2 (ru) *	2007-11-16	2009-10-20	Закрытое Акционерное Общество "Биокад"	Фармацевтическая композиция для парентеральной доставки в форме лиофилизата и способ ее получения
ES2344674B1 (es) *	2008-08-07	2011-06-29	Gp Pharm, S.A.	Composicion farmaceutica inyectable de taxanos.
US8541360B2 (en) *	2008-11-19	2013-09-24	Ben Venue Laboratories, Inc.	Parenteral formulations comprising sugar-based esters and ethers
WO2012156999A1 (en) *	2011-05-19	2012-11-22	Manu Chaudhary	Ready to use docetaxel formulation
ES2687705T3 (es)	2012-07-19	2018-10-26	Fujifilm Corporation	Composición líquida que contiene un principio activo a base de taxano, proceso de producción de la misma y preparación medicinal líquida
EA022182B1 (ru) *	2012-12-24	2015-11-30	Общество С Ограниченной Ответственностью "Технология Лекарств"	Способ получения липосомальной формы доцетаксела

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4534899A (en) *	1981-07-20	1985-08-13	Lipid Specialties, Inc.	Synthetic phospholipid compounds
US4507217A (en) *	1983-03-07	1985-03-26	Lipid Specialties, Inc.	Magnetic compositions and magnetic memory devices prepared therefrom
US5411947A (en) *	1989-06-28	1995-05-02	Vestar, Inc.	Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
EP0706373B1 (de) *	1992-03-23	2000-07-19	Georgetown University	In liposomen verkapseltes taxol und verwendungsverfahren
AU6833994A (en) *	1993-05-17	1994-12-12	Liposome Company, Inc., The	Incorporation of taxol into liposomes and gels
WO1994026253A1 (en) *	1993-05-19	1994-11-24	The Liposome Company, Inc.	Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
US5415869A (en) *	1993-11-12	1995-05-16	The Research Foundation Of State University Of New York	Taxol formulation

1994
- 1994-04-25 FR FR9404951A patent/FR2718963B1/fr not_active Expired - Lifetime
1995
- 1995-04-24 ES ES95918046T patent/ES2160163T3/es not_active Expired - Lifetime
- 1995-04-24 PL PL95316942A patent/PL179623B1/pl not_active IP Right Cessation
- 1995-04-24 JP JP52740795A patent/JP3950993B2/ja not_active Expired - Fee Related
- 1995-04-24 GE GEAP19953465A patent/GEP20002069B/en unknown
- 1995-04-24 CN CNB951927280A patent/CN1283243C/zh not_active Expired - Fee Related
- 1995-04-24 NZ NZ285122A patent/NZ285122A/en not_active IP Right Cessation
- 1995-04-24 AU AU24126/95A patent/AU691283B2/en not_active Ceased
- 1995-04-24 DK DK95918046T patent/DK0758231T3/da active
- 1995-04-24 PT PT95918046T patent/PT758231E/pt unknown
- 1995-04-24 HU HU9602942A patent/HU225971B1/hu not_active IP Right Cessation
- 1995-04-24 BR BR9507846A patent/BR9507846A/pt not_active IP Right Cessation
- 1995-04-24 AT AT95918046T patent/ATE202931T1/de active
- 1995-04-24 CZ CZ963093A patent/CZ285720B6/cs not_active IP Right Cessation
- 1995-04-24 KR KR1019960705981A patent/KR100401119B1/ko not_active Expired - Fee Related
- 1995-04-24 WO PCT/FR1995/000532 patent/WO1995028923A1/fr not_active Ceased
- 1995-04-24 DE DE69521693T patent/DE69521693T2/de not_active Expired - Lifetime
- 1995-04-24 EP EP95918046A patent/EP0758231B1/de not_active Expired - Lifetime
- 1995-04-24 SK SK1356-96A patent/SK283255B6/sk not_active IP Right Cessation
- 1995-04-24 TW TW084104022A patent/TW416849B/zh not_active IP Right Cessation
- 1995-04-24 RU RU96122523/14A patent/RU2157200C2/ru not_active IP Right Cessation
- 1995-04-25 ZA ZA953358A patent/ZA953358B/xx unknown
- 1995-04-25 US US08/428,261 patent/US5670536A/en not_active Expired - Lifetime
1996
- 1996-10-18 NO NO19964433A patent/NO314745B1/no not_active IP Right Cessation
- 1996-10-24 FI FI964285A patent/FI118204B/fi not_active IP Right Cessation
2001
- 2001-07-12 GR GR20010400339T patent/GR3036211T3/el unknown

Also Published As

Publication number	Publication date
GEP20002069B (en)	2000-05-10
CZ309396A3 (en)	1997-01-15
SK283255B6 (sk)	2003-04-01
NO964433D0 (no)	1996-10-18
CN1283243C (zh)	2006-11-08
FI118204B (fi)	2007-08-31
DE69521693D1 (de)	2001-08-16
FR2718963B1 (fr)	1996-05-24
DK0758231T3 (da)	2001-09-24
AU2412695A (en)	1995-11-16
ATE202931T1 (de)	2001-07-15
PT758231E (pt)	2001-11-30
PL179623B1 (pl)	2000-10-31
SK135696A3 (en)	1997-05-07
FR2718963A1 (fr)	1995-10-27
HU225971B1 (en)	2008-01-28
FI964285L (fi)	1996-10-24
BR9507846A (pt)	1997-09-16
ES2160163T3 (es)	2001-11-01
KR100401119B1 (ko)	2004-03-19
JPH09512261A (ja)	1997-12-09
EP0758231B1 (de)	2001-07-11
NO314745B1 (no)	2003-05-19
KR970702033A (ko)	1997-05-13
NZ285122A (en)	1998-06-26
JP3950993B2 (ja)	2007-08-01
RU2157200C2 (ru)	2000-10-10
FI964285A0 (fi)	1996-10-24
GR3036211T3 (en)	2001-10-31
EP0758231A1 (de)	1997-02-19
NO964433L (no)	1996-10-18
AU691283B2 (en)	1998-05-14
CN1146722A (zh)	1997-04-02
HUT75513A (en)	1997-05-28
TW416849B (en)	2001-01-01
DE69521693T2 (de)	2002-05-02
PL316942A1 (en)	1997-02-17
CZ285720B6 (cs)	1999-10-13
US5670536A (en)	1997-09-23
HU9602942D0 (en)	1996-12-30
WO1995028923A1 (fr)	1995-11-02

Publication	Publication Date	Title
ZA953358B (en)	1996-01-17	New pharmaceutical composition based on taxoids
MX9306924A (es)	1994-05-31	Composiciones antitumorales que contienen derivados de taxano.
ATE257386T1 (de)	2004-01-15	Pharmazeutische zusammensetzungen enthaltend eine mischung von selbstvernetzter und nichtselbstvernetzter hyaluronsäure zur behandlung von arthropathien
ATE314844T1 (de)	2006-02-15	Verfahren und zusammensetzungen zur verabreichung von taxanen
ATE324907T1 (de)	2006-06-15	Verbindung und arzneizusammensetzung zur verabreichung von wirkstoffen
PT977564E (pt)	2005-08-31	Forscolina para promocao da massa corporal magra
HUP0301405A2 (hu)	2003-08-28	Fokozott oldékonyságú gyógyhatású komponenseket tartalmazó készítmények
TR200002299T2 (tr)	2000-11-21	Epotilon kompozisyonları.
DK0839026T3 (da)	2002-01-21	Micellære polyether-blokcopolymerkompositioner til målretning af biologiske midler
DE69307977D1 (de)	1997-03-20	Stabilisierte Derivate von Vitamin D2 und D3 enthaltende pharmazeutische Zusammensetzungen
AR021370A1 (es)	2002-07-17	Composiciones farmaceuticas inyectables estabilizadas que contienen agentes anti-neoplasicos taxoides
IL109613A0 (en)	1994-08-26	Inclusion complexes of taxol or taxotere or taxus extract formed with cyclodextrins, their preparation and use
UA74388C2 (uk)	2005-12-15	Фармацевтичні композиції тизоксаніду і нітазоксаніду
DK0917460T3 (da)	2002-03-25	Cyclosporin-formulering
ATE297217T1 (de)	2005-06-15	Zusammensetzung zur vorbeugung und behandlung von transplantatabstossung
ATE241376T1 (de)	2003-06-15	Zusammensetzungen, die dolastatin-15-analoge in kombination mit taxane und dessen derivaten enthalten
ATE75619T1 (de)	1992-05-15	Bestaendige therapeutische zusammensetzungen, basierend auf hydrophobem pflanzlichem oel und verfahren zu ihrer herstellung.
MX9604984A (es)	1998-02-28	Composiciones farmaceuticas a base de derivados de la clase de los taxanos.
ES2179667T3 (es)	2003-01-16	Nuevas formulaciones inyectables que contienen ramoplanina.
JPS5758630A (en)	1982-04-08	Interferon inducer
UA36813A (uk)	2001-04-16	Збір для лікування серцевих неврозів, стресових станів, гіпертонічної хвороби, радіофобії (лон-5)