GR3036211T3 - Taxane class derivative based pharmaceutical compositions - Google Patents
Taxane class derivative based pharmaceutical compositionsInfo
- Publication number
- GR3036211T3 GR3036211T3 GR20010400339T GR20010400339T GR3036211T3 GR 3036211 T3 GR3036211 T3 GR 3036211T3 GR 20010400339 T GR20010400339 T GR 20010400339T GR 20010400339 T GR20010400339 T GR 20010400339T GR 3036211 T3 GR3036211 T3 GR 3036211T3
- Authority
- GR
- Greece
- Prior art keywords
- pharmaceutical compositions
- based pharmaceutical
- derivative based
- taxane class
- class derivative
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
- ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 2
- 229960003668 docetaxel Drugs 0.000 abstract 2
- 150000003904 phospholipids Chemical class 0.000 abstract 2
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9404951A FR2718963B1 (fr) | 1994-04-25 | 1994-04-25 | Nouvelle composition pharmaceutique à base de taxoïdes. |
| PCT/FR1995/000532 WO1995028923A1 (fr) | 1994-04-25 | 1995-04-24 | Compositions pharmaceutiques a base de derives de la classe des taxanes |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GR3036211T3 true GR3036211T3 (en) | 2001-10-31 |
Family
ID=9462475
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GR20010400339T GR3036211T3 (en) | 1994-04-25 | 2001-07-12 | Taxane class derivative based pharmaceutical compositions |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US5670536A (el) |
| EP (1) | EP0758231B1 (el) |
| JP (1) | JP3950993B2 (el) |
| KR (1) | KR100401119B1 (el) |
| CN (1) | CN1283243C (el) |
| AT (1) | ATE202931T1 (el) |
| AU (1) | AU691283B2 (el) |
| BR (1) | BR9507846A (el) |
| CZ (1) | CZ285720B6 (el) |
| DE (1) | DE69521693T2 (el) |
| DK (1) | DK0758231T3 (el) |
| ES (1) | ES2160163T3 (el) |
| FI (1) | FI118204B (el) |
| FR (1) | FR2718963B1 (el) |
| GE (1) | GEP20002069B (el) |
| GR (1) | GR3036211T3 (el) |
| HU (1) | HU225971B1 (el) |
| NO (1) | NO314745B1 (el) |
| NZ (1) | NZ285122A (el) |
| PL (1) | PL179623B1 (el) |
| PT (1) | PT758231E (el) |
| RU (1) | RU2157200C2 (el) |
| SK (1) | SK283255B6 (el) |
| TW (1) | TW416849B (el) |
| WO (1) | WO1995028923A1 (el) |
| ZA (1) | ZA953358B (el) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2698871B1 (fr) | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
| US6096331A (en) * | 1993-02-22 | 2000-08-01 | Vivorx Pharmaceuticals, Inc. | Methods and compositions useful for administration of chemotherapeutic agents |
| US5439686A (en) * | 1993-02-22 | 1995-08-08 | Vivorx Pharmaceuticals, Inc. | Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor |
| US6395770B1 (en) | 1995-10-26 | 2002-05-28 | Baker Norton Pharmaceuticals, Inc. | Method and compositions for administering taxanes orally to human patients |
| US6245805B1 (en) | 1995-10-26 | 2001-06-12 | Baker Norton Pharmaceuticals, Inc. | Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents |
| BRPI9810945B8 (pt) * | 1997-06-27 | 2021-05-25 | Abraxis Bioscience Inc | formulações de agentes farmacológicos, métodos para sua preparação e métodos para uso das mesmas |
| US8853260B2 (en) | 1997-06-27 | 2014-10-07 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
| SK287775B6 (sk) * | 1998-02-05 | 2011-09-05 | Novartis Ag | Farmaceutická formulácia obsahujúca epothilon, infúzny roztok a použitie farmaceutickej formulácie |
| US6071952A (en) * | 1998-12-02 | 2000-06-06 | Mylan Pharmaceuticals, Inc. | Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents |
| GB9920548D0 (en) * | 1999-08-31 | 1999-11-03 | Rhone Poulenc Rorer Sa | Treatment of hepatocellular carcinoma |
| RU2213746C1 (ru) * | 2002-02-15 | 2003-10-10 | Научно-исследовательский институт физико-химической медицины | Компонент, обеспечивающий поверхностно-активные свойства композиций - аналогов препаратов для заместительной сурфактантной терапии легочных заболеваний |
| DE10255285A1 (de) * | 2002-11-26 | 2004-06-03 | Mcs Micro Carrier Systems Gmbh | Selbst formende Phospholipid-Gele |
| US20050152979A1 (en) * | 2003-09-05 | 2005-07-14 | Cell Therapeutics, Inc. | Hydrophobic drug compositions containing reconstitution enhancer |
| US8557861B2 (en) * | 2004-09-28 | 2013-10-15 | Mast Therapeutics, Inc. | Low oil emulsion compositions for delivering taxoids and other insoluble drugs |
| US7446126B2 (en) * | 2004-10-08 | 2008-11-04 | Indena S.P.A. | Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel |
| TWI376239B (en) * | 2006-02-01 | 2012-11-11 | Andrew Xian Chen | Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof |
| JP2010524919A (ja) * | 2007-04-23 | 2010-07-22 | サン、ファーマスーティカル、インダストリーズ、リミテッド | 医薬組成物 |
| EP1987813A1 (en) * | 2007-05-04 | 2008-11-05 | Pharmatex Italia Srl | Injectable pharmaceutical formulation of taxoids in stable liposomes |
| RU2370261C2 (ru) * | 2007-08-03 | 2009-10-20 | Закрытое Акционерное Общество "Биокад" | Стабильная эмульсия для парентерального введения плохо растворимых в воде соединений, обладающих противоопухолевой активностью, и способ ее получения |
| EP2205215A2 (en) * | 2007-10-01 | 2010-07-14 | Intas Pharmaceuticals Limited | Docetaxel injectable composition, being absolutely free of ethanol |
| CN101971189A (zh) * | 2007-11-07 | 2011-02-09 | 爱墨菲特有限公司 | 压痕泡沫数字扫描仪 |
| RU2370258C2 (ru) * | 2007-11-16 | 2009-10-20 | Закрытое Акционерное Общество "Биокад" | Фармацевтическая композиция для парентеральной доставки в форме лиофилизата и способ ее получения |
| ES2344674B1 (es) * | 2008-08-07 | 2011-06-29 | Gp Pharm, S.A. | Composicion farmaceutica inyectable de taxanos. |
| US8541360B2 (en) * | 2008-11-19 | 2013-09-24 | Ben Venue Laboratories, Inc. | Parenteral formulations comprising sugar-based esters and ethers |
| WO2012156999A1 (en) * | 2011-05-19 | 2012-11-22 | Manu Chaudhary | Ready to use docetaxel formulation |
| ES2687705T3 (es) | 2012-07-19 | 2018-10-26 | Fujifilm Corporation | Composición líquida que contiene un principio activo a base de taxano, proceso de producción de la misma y preparación medicinal líquida |
| EA022182B1 (ru) * | 2012-12-24 | 2015-11-30 | Общество С Ограниченной Ответственностью "Технология Лекарств" | Способ получения липосомальной формы доцетаксела |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4534899A (en) * | 1981-07-20 | 1985-08-13 | Lipid Specialties, Inc. | Synthetic phospholipid compounds |
| US4507217A (en) * | 1983-03-07 | 1985-03-26 | Lipid Specialties, Inc. | Magnetic compositions and magnetic memory devices prepared therefrom |
| US5411947A (en) * | 1989-06-28 | 1995-05-02 | Vestar, Inc. | Method of converting a drug to an orally available form by covalently bonding a lipid to the drug |
| EP0706373B1 (en) * | 1992-03-23 | 2000-07-19 | Georgetown University | Liposome encapsulated taxol and a method of using the same |
| AU6833994A (en) * | 1993-05-17 | 1994-12-12 | Liposome Company, Inc., The | Incorporation of taxol into liposomes and gels |
| WO1994026253A1 (en) * | 1993-05-19 | 1994-11-24 | The Liposome Company, Inc. | Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer |
| US5415869A (en) * | 1993-11-12 | 1995-05-16 | The Research Foundation Of State University Of New York | Taxol formulation |
-
1994
- 1994-04-25 FR FR9404951A patent/FR2718963B1/fr not_active Expired - Lifetime
-
1995
- 1995-04-24 ES ES95918046T patent/ES2160163T3/es not_active Expired - Lifetime
- 1995-04-24 PL PL95316942A patent/PL179623B1/pl not_active IP Right Cessation
- 1995-04-24 JP JP52740795A patent/JP3950993B2/ja not_active Expired - Fee Related
- 1995-04-24 GE GEAP19953465A patent/GEP20002069B/en unknown
- 1995-04-24 CN CNB951927280A patent/CN1283243C/zh not_active Expired - Fee Related
- 1995-04-24 NZ NZ285122A patent/NZ285122A/en not_active IP Right Cessation
- 1995-04-24 AU AU24126/95A patent/AU691283B2/en not_active Ceased
- 1995-04-24 DK DK95918046T patent/DK0758231T3/da active
- 1995-04-24 PT PT95918046T patent/PT758231E/pt unknown
- 1995-04-24 HU HU9602942A patent/HU225971B1/hu not_active IP Right Cessation
- 1995-04-24 BR BR9507846A patent/BR9507846A/pt not_active IP Right Cessation
- 1995-04-24 AT AT95918046T patent/ATE202931T1/de active
- 1995-04-24 CZ CZ963093A patent/CZ285720B6/cs not_active IP Right Cessation
- 1995-04-24 KR KR1019960705981A patent/KR100401119B1/ko not_active Expired - Fee Related
- 1995-04-24 WO PCT/FR1995/000532 patent/WO1995028923A1/fr not_active Ceased
- 1995-04-24 DE DE69521693T patent/DE69521693T2/de not_active Expired - Lifetime
- 1995-04-24 EP EP95918046A patent/EP0758231B1/fr not_active Expired - Lifetime
- 1995-04-24 SK SK1356-96A patent/SK283255B6/sk not_active IP Right Cessation
- 1995-04-24 TW TW084104022A patent/TW416849B/zh not_active IP Right Cessation
- 1995-04-24 RU RU96122523/14A patent/RU2157200C2/ru not_active IP Right Cessation
- 1995-04-25 ZA ZA953358A patent/ZA953358B/xx unknown
- 1995-04-25 US US08/428,261 patent/US5670536A/en not_active Expired - Lifetime
-
1996
- 1996-10-18 NO NO19964433A patent/NO314745B1/no not_active IP Right Cessation
- 1996-10-24 FI FI964285A patent/FI118204B/fi not_active IP Right Cessation
-
2001
- 2001-07-12 GR GR20010400339T patent/GR3036211T3/el unknown
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