DK0758231T3 - Farmaceutiske præparater på basis af derivater tilhørende taxanklassen - Google Patents

Farmaceutiske præparater på basis af derivater tilhørende taxanklassen

Info

Publication number: DK0758231T3
Authority: DK; Denmark
Prior art keywords: pharmaceutical preparations; preparations based; taxane class; derivatives belonging; docetaxel
Prior art date: 1994-04-25

Application number

DK95918046T

Other languages

English (en)

Inventor

Manfred Durr

Joerg-Christian Hager

Armin Wendel

Original Assignee

Aventis Pharma Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-04-25

Filing date

1995-04-24

Publication date

2001-09-24

1995-04-24 Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa

2001-09-24 Application granted granted Critical

2001-09-24 Publication of DK0758231T3 publication Critical patent/DK0758231T3/da

Links

239000000825 pharmaceutical preparation Substances 0.000 title 1
DKPFODGZWDEEBT-QFIAKTPHSA-N taxane Chemical class C([C@]1(C)CCC[C@@H](C)[C@H]1C1)C[C@H]2[C@H](C)CC[C@@H]1C2(C)C DKPFODGZWDEEBT-QFIAKTPHSA-N 0.000 title 1
ZDZOTLJHXYCWBA-VCVYQWHSSA-N N-debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol Chemical compound O([C@H]1[C@H]2[C@@](C([C@H](O)C3=C(C)[C@@H](OC(=O)[C@H](O)[C@@H](NC(=O)OC(C)(C)C)C=4C=CC=CC=4)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 ZDZOTLJHXYCWBA-VCVYQWHSSA-N 0.000 abstract 2
229960003668 docetaxel Drugs 0.000 abstract 2
150000003904 phospholipids Chemical class 0.000 abstract 2
238000002347 injection Methods 0.000 abstract 1
239000007924 injection Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biophysics (AREA)
Molecular Biology (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Dermatology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Epoxy Compounds (AREA)
Medicinal Preparation (AREA)

DK95918046T 1994-04-25 1995-04-24 Farmaceutiske præparater på basis af derivater tilhørende taxanklassen DK0758231T3 (da)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9404951A FR2718963B1 (fr)	1994-04-25	1994-04-25	Nouvelle composition pharmaceutique à base de taxoïdes.
PCT/FR1995/000532 WO1995028923A1 (fr)	1994-04-25	1995-04-24	Compositions pharmaceutiques a base de derives de la classe des taxanes

Publications (1)

Publication Number	Publication Date
DK0758231T3 true DK0758231T3 (da)	2001-09-24

Family

ID=9462475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DK95918046T DK0758231T3 (da)	1994-04-25	1995-04-24	Farmaceutiske præparater på basis af derivater tilhørende taxanklassen

Country Status (26)

Country	Link
US (1)	US5670536A (da)
EP (1)	EP0758231B1 (da)
JP (1)	JP3950993B2 (da)
KR (1)	KR100401119B1 (da)
CN (1)	CN1283243C (da)
AT (1)	ATE202931T1 (da)
AU (1)	AU691283B2 (da)
BR (1)	BR9507846A (da)
CZ (1)	CZ285720B6 (da)
DE (1)	DE69521693T2 (da)
DK (1)	DK0758231T3 (da)
ES (1)	ES2160163T3 (da)
FI (1)	FI118204B (da)
FR (1)	FR2718963B1 (da)
GE (1)	GEP20002069B (da)
GR (1)	GR3036211T3 (da)
HU (1)	HU225971B1 (da)
NO (1)	NO314745B1 (da)
NZ (1)	NZ285122A (da)
PL (1)	PL179623B1 (da)
PT (1)	PT758231E (da)
RU (1)	RU2157200C2 (da)
SK (1)	SK283255B6 (da)
TW (1)	TW416849B (da)
WO (1)	WO1995028923A1 (da)
ZA (1)	ZA953358B (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2698871B1 (fr)	1992-12-09	1995-02-24	Rhone Poulenc Rorer Sa	Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5439686A (en) *	1993-02-22	1995-08-08	Vivorx Pharmaceuticals, Inc.	Methods for in vivo delivery of substantially water insoluble pharmacologically active agents and compositions useful therefor
US6096331A (en) *	1993-02-22	2000-08-01	Vivorx Pharmaceuticals, Inc.	Methods and compositions useful for administration of chemotherapeutic agents
US6245805B1 (en) *	1995-10-26	2001-06-12	Baker Norton Pharmaceuticals, Inc.	Method, compositions and kits for increasing the oral bioavailability of pharmaceutical agents
US6395770B1 (en)	1995-10-26	2002-05-28	Baker Norton Pharmaceuticals, Inc.	Method and compositions for administering taxanes orally to human patients
US8853260B2 (en)	1997-06-27	2014-10-07	Abraxis Bioscience, Llc	Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
ES2435944T3 (es) *	1997-06-27	2013-12-26	Abraxis Bioscience, Llc	Nuevas formulaciones de agentes farmacológicos, métodos para su preparación y métodos para su uso
MY125921A (en) *	1998-02-05	2006-08-30	Novartis Ag	Compositions containing organic compounds
US6071952A (en) *	1998-12-02	2000-06-06	Mylan Pharmaceuticals, Inc.	Stabilized injectable pharmaceutical compositions containing taxoid anti-neoplastic agents
GB9920548D0 (en) *	1999-08-31	1999-11-03	Rhone Poulenc Rorer Sa	Treatment of hepatocellular carcinoma
RU2213746C1 (ru) *	2002-02-15	2003-10-10	Научно-исследовательский институт физико-химической медицины	Компонент, обеспечивающий поверхностно-активные свойства композиций - аналогов препаратов для заместительной сурфактантной терапии легочных заболеваний
DE10255285A1 (de) *	2002-11-26	2004-06-03	Mcs Micro Carrier Systems Gmbh	Selbst formende Phospholipid-Gele
US20050152979A1 (en) *	2003-09-05	2005-07-14	Cell Therapeutics, Inc.	Hydrophobic drug compositions containing reconstitution enhancer
US8557861B2 (en) *	2004-09-28	2013-10-15	Mast Therapeutics, Inc.	Low oil emulsion compositions for delivering taxoids and other insoluble drugs
US7446126B2 (en) *	2004-10-08	2008-11-04	Indena S.P.A.	Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel
TWI376239B (en) *	2006-02-01	2012-11-11	Andrew Xian Chen	Vitamin e succinate stabilized pharmaceutical compositions, methods for the preparation and the use thereof
CA2683712A1 (en) *	2007-04-20	2009-01-15	Sun Pharmaceutical Industries Limited	Pharmaceutical compositions
EP1987813A1 (en) *	2007-05-04	2008-11-05	Pharmatex Italia Srl	Injectable pharmaceutical formulation of taxoids in stable liposomes
RU2370261C2 (ru) *	2007-08-03	2009-10-20	Закрытое Акционерное Общество "Биокад"	Стабильная эмульсия для парентерального введения плохо растворимых в воде соединений, обладающих противоопухолевой активностью, и способ ее получения
EP2205215A2 (en) *	2007-10-01	2010-07-14	Intas Pharmaceuticals Limited	Docetaxel injectable composition, being absolutely free of ethanol
CN101971189A (zh) *	2007-11-07	2011-02-09	爱墨菲特有限公司	压痕泡沫数字扫描仪
RU2370258C2 (ru) *	2007-11-16	2009-10-20	Закрытое Акционерное Общество "Биокад"	Фармацевтическая композиция для парентеральной доставки в форме лиофилизата и способ ее получения
ES2344674B1 (es) *	2008-08-07	2011-06-29	Gp Pharm, S.A.	Composicion farmaceutica inyectable de taxanos.
US8541360B2 (en) *	2008-11-19	2013-09-24	Ben Venue Laboratories, Inc.	Parenteral formulations comprising sugar-based esters and ethers
WO2012156999A1 (en) *	2011-05-19	2012-11-22	Manu Chaudhary	Ready to use docetaxel formulation
JP5847942B2 (ja)	2012-07-19	2016-01-27	富士フイルム株式会社	タキサン系活性成分含有液体組成物、その製造方法及び液体製剤
EA022182B1 (ru) *	2012-12-24	2015-11-30	Общество С Ограниченной Ответственностью "Технология Лекарств"	Способ получения липосомальной формы доцетаксела

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4534899A (en) *	1981-07-20	1985-08-13	Lipid Specialties, Inc.	Synthetic phospholipid compounds
US4507217A (en) *	1983-03-07	1985-03-26	Lipid Specialties, Inc.	Magnetic compositions and magnetic memory devices prepared therefrom
US5411947A (en) *	1989-06-28	1995-05-02	Vestar, Inc.	Method of converting a drug to an orally available form by covalently bonding a lipid to the drug
DE69329073T2 (de) *	1992-03-23	2001-01-18	Georgetown University, Washington	In liposomen verkapseltes taxol und verwendungsverfahren
WO1994026254A1 (en) *	1993-05-17	1994-11-24	The Liposome Company, Inc.	Incorporation of taxol into liposomes and gels
AU6832794A (en) *	1993-05-19	1994-12-12	Liposome Company, Inc., The	Liposome having a multicomponent bilayer which contains a bioactive agent as an integral component of the bilayer
US5415869A (en) *	1993-11-12	1995-05-16	The Research Foundation Of State University Of New York	Taxol formulation

1994
- 1994-04-25 FR FR9404951A patent/FR2718963B1/fr not_active Expired - Lifetime
1995
- 1995-04-24 BR BR9507846A patent/BR9507846A/pt not_active IP Right Cessation
- 1995-04-24 HU HU9602942A patent/HU225971B1/hu not_active IP Right Cessation
- 1995-04-24 AT AT95918046T patent/ATE202931T1/de active
- 1995-04-24 SK SK1356-96A patent/SK283255B6/sk not_active IP Right Cessation
- 1995-04-24 DK DK95918046T patent/DK0758231T3/da active
- 1995-04-24 CN CNB951927280A patent/CN1283243C/zh not_active Expired - Fee Related
- 1995-04-24 DE DE69521693T patent/DE69521693T2/de not_active Expired - Lifetime
- 1995-04-24 GE GEAP19953465A patent/GEP20002069B/en unknown
- 1995-04-24 WO PCT/FR1995/000532 patent/WO1995028923A1/fr not_active Ceased
- 1995-04-24 CZ CZ963093A patent/CZ285720B6/cs not_active IP Right Cessation
- 1995-04-24 KR KR1019960705981A patent/KR100401119B1/ko not_active Expired - Fee Related
- 1995-04-24 RU RU96122523/14A patent/RU2157200C2/ru not_active IP Right Cessation
- 1995-04-24 AU AU24126/95A patent/AU691283B2/en not_active Ceased
- 1995-04-24 ES ES95918046T patent/ES2160163T3/es not_active Expired - Lifetime
- 1995-04-24 TW TW084104022A patent/TW416849B/zh not_active IP Right Cessation
- 1995-04-24 JP JP52740795A patent/JP3950993B2/ja not_active Expired - Fee Related
- 1995-04-24 NZ NZ285122A patent/NZ285122A/en not_active IP Right Cessation
- 1995-04-24 PT PT95918046T patent/PT758231E/pt unknown
- 1995-04-24 EP EP95918046A patent/EP0758231B1/fr not_active Expired - Lifetime
- 1995-04-24 PL PL95316942A patent/PL179623B1/pl not_active IP Right Cessation
- 1995-04-25 US US08/428,261 patent/US5670536A/en not_active Expired - Lifetime
- 1995-04-25 ZA ZA953358A patent/ZA953358B/xx unknown
1996
- 1996-10-18 NO NO19964433A patent/NO314745B1/no not_active IP Right Cessation
- 1996-10-24 FI FI964285A patent/FI118204B/fi not_active IP Right Cessation
2001
- 2001-07-12 GR GR20010400339T patent/GR3036211T3/el unknown

Also Published As

Publication number	Publication date
CZ309396A3 (en)	1997-01-15
ES2160163T3 (es)	2001-11-01
KR100401119B1 (ko)	2004-03-19
PT758231E (pt)	2001-11-30
NO314745B1 (no)	2003-05-19
JP3950993B2 (ja)	2007-08-01
DE69521693T2 (de)	2002-05-02
NO964433D0 (no)	1996-10-18
US5670536A (en)	1997-09-23
HU225971B1 (en)	2008-01-28
EP0758231B1 (fr)	2001-07-11
PL179623B1 (pl)	2000-10-31
HUT75513A (en)	1997-05-28
GR3036211T3 (en)	2001-10-31
HU9602942D0 (en)	1996-12-30
JPH09512261A (ja)	1997-12-09
CZ285720B6 (cs)	1999-10-13
DE69521693D1 (de)	2001-08-16
FR2718963A1 (fr)	1995-10-27
ATE202931T1 (de)	2001-07-15
GEP20002069B (en)	2000-05-10
RU2157200C2 (ru)	2000-10-10
BR9507846A (pt)	1997-09-16
PL316942A1 (en)	1997-02-17
SK283255B6 (sk)	2003-04-01
FR2718963B1 (fr)	1996-05-24
NO964433L (no)	1996-10-18
FI964285L (fi)	1996-10-24
AU2412695A (en)	1995-11-16
CN1283243C (zh)	2006-11-08
FI964285A0 (fi)	1996-10-24
CN1146722A (zh)	1997-04-02
AU691283B2 (en)	1998-05-14
EP0758231A1 (fr)	1997-02-19
SK135696A3 (en)	1997-05-07
FI118204B (fi)	2007-08-31
TW416849B (en)	2001-01-01
WO1995028923A1 (fr)	1995-11-02
NZ285122A (en)	1998-06-26
ZA953358B (en)	1996-01-17
KR970702033A (ko)	1997-05-13

Publication	Publication Date	Title
NO964433D0 (no)	1996-10-18	Farmasöytiske preparater på basis av derivater av taxanklassen
MX9306924A (es)	1994-05-31	Composiciones antitumorales que contienen derivados de taxano.
DK0977562T3 (da)	2006-05-01	Fremgangsmåder og sammensætninger til indgivelse af taxaner
DE69727158D1 (de)	2004-02-12	Pharmazeutische zusammensetzungen enthaltend eine mischung von selbstvernetzter und nichtselbstvernetzter hyaluronsäure zur behandlung von arthropathien
TR200002299T2 (tr)	2000-11-21	Epotilon kompozisyonları.
HRP20020787B1 (hr)	2012-06-30	Postupak liječenja upotrebom kompleksa ligand-imunogen
DE60138222D1 (de)	2009-05-14	Modulierung von il-2 und il-15 vermittelten t zellantworten
DK0993831T3 (da)	2008-03-25	Forbindelser og præparater til tilförsel af aktive stoffer
FI971776A0 (fi)	1997-04-25	Yhdisteet ja koostumukset aktiivisten aineiden antamiseksi
NO307205B1 (no)	2000-02-28	Preparater basert på virkestoffer fra taxanklassen samt perfusjonspreparater inneholdende disse
SV2004001556A (es)	2004-03-08	Preparaciones acidas de insulina con establidad mejorada
HUP0301405A2 (hu)	2003-08-28	Fokozott oldékonyságú gyógyhatású komponenseket tartalmazó készítmények
HRP20040354B1 (en)	2012-10-31	Novel cyclosporin analog microemulsion preconcentrates
BR0008590A (pt)	2001-10-30	Agente de entrega polimérico, composição, formade unidade de dosagem, método para administrarum agente biologicamente ativo a um animalnecessitando o agente, método para preparar umacomposição; e composto
BR9810495A (pt)	2000-09-12	Composição farmacêutica
ATE148630T1 (de)	1997-02-15	Stabilisierte derivate von vitamin d2 und d3 enthaltende pharmazeutische zusammensetzungen
AR021370A1 (es)	2002-07-17	Composiciones farmaceuticas inyectables estabilizadas que contienen agentes anti-neoplasicos taxoides
DK0698018T3 (da)	2003-02-10	Inklusionskomplekser af Taxol eller Taxotere eller Taxus-ekstrakt dannet med cyclodextriner, deres fremstilling og anvendelse
EE200200087A (et)	2003-04-15	Kompositsioon hepatotsellulaarse kartsinoomi raviks
UA48958C2 (uk)	2002-09-16	9-o-оксимові похідні еритроміцину а та фармацевтична композиція на їх основі
EP1051966A3 (de)	2001-01-10	Kosmetische und/oder pharmazeutische Zubereitungen mit einem Gehalt an Alkyl- und/oder Alkenyloligoglykosiden, Fettsäurepartialglyceriden, Esterquats und hydroxyalkylertem Guar als Verdickungsmittel
DK1061938T3 (da)	2002-02-11	Orale sammensætninger med cytotoksiske proteiner i lav dosis
DK1100463T3 (da)	2003-01-20	Injicerbare formuleringer indeholdende ramoplanin
DE3778826D1 (de)	1992-06-11	Bestaendige therapeutische zusammensetzungen, basierend auf hydrophobem pflanzlichem oel und verfahren zu ihrer herstellung.
MX9604984A (es)	1998-02-28	Composiciones farmaceuticas a base de derivados de la clase de los taxanos.