ATE232298T1 - Bioluminenztest für agonisten oder antagonisten eines kalzium-gekuppelten-rezeptors - Google Patents

Bioluminenztest für agonisten oder antagonisten eines kalzium-gekuppelten-rezeptors

Info

Publication number
ATE232298T1
ATE232298T1 AT99930956T AT99930956T ATE232298T1 AT E232298 T1 ATE232298 T1 AT E232298T1 AT 99930956 T AT99930956 T AT 99930956T AT 99930956 T AT99930956 T AT 99930956T AT E232298 T1 ATE232298 T1 AT E232298T1
Authority
AT
Austria
Prior art keywords
calcium
coupled receptor
bioluminence
agonists
antagonists
Prior art date
Application number
AT99930956T
Other languages
English (en)
Inventor
Vincent Dupriez
Michel Detheux
Marc Parmentier
Original Assignee
Euroscreen Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8237065&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE232298(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Euroscreen Sa filed Critical Euroscreen Sa
Application granted granted Critical
Publication of ATE232298T1 publication Critical patent/ATE232298T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT99930956T 1998-07-06 1999-07-06 Bioluminenztest für agonisten oder antagonisten eines kalzium-gekuppelten-rezeptors ATE232298T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP98870149 1998-07-06
PCT/BE1999/000087 WO2000002045A2 (en) 1998-07-06 1999-07-06 Bioluminescent assay for agonists or antagonists of a calcium-coupled receptor

Publications (1)

Publication Number Publication Date
ATE232298T1 true ATE232298T1 (de) 2003-02-15

Family

ID=8237065

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99930956T ATE232298T1 (de) 1998-07-06 1999-07-06 Bioluminenztest für agonisten oder antagonisten eines kalzium-gekuppelten-rezeptors

Country Status (9)

Country Link
US (1) US6872538B1 (de)
EP (1) EP1145002B2 (de)
JP (1) JP3495987B2 (de)
AT (1) ATE232298T1 (de)
CA (1) CA2336929C (de)
DE (1) DE69905291T3 (de)
DK (1) DK1145002T4 (de)
ES (1) ES2192060T5 (de)
WO (1) WO2000002045A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6025154A (en) 1995-06-06 2000-02-15 Human Genome Sciences, Inc. Polynucleotides encoding human G-protein chemokine receptor HDGNR10
US6248542B1 (en) * 1997-12-09 2001-06-19 Massachusetts Institute Of Technology Optoelectronic sensor
DE10008373C2 (de) * 2000-02-23 2002-11-28 Helmut Adelsberger Verfahren und Vorrichtung zur Bestimmung der Ionenkanalaktivität
US8216797B2 (en) 2001-02-07 2012-07-10 Massachusetts Institute Of Technology Pathogen detection biosensor
ATE345497T1 (de) * 2001-02-07 2006-12-15 Massachusetts Inst Technology Optoelektronisches nachweissystem
US7422860B2 (en) 2001-02-07 2008-09-09 Massachusetts Institute Of Technology Optoelectronic detection system
US7175988B2 (en) 2001-02-09 2007-02-13 Human Genome Sciences, Inc. Human G-protein Chemokine Receptor (CCR5) HDGNR10
AU2002256694A1 (en) * 2001-03-20 2002-10-03 Euroscreen S.A. Screening, diagnostic and/or dosage method and device of an agonist and/or antagonist for a calcium-coupled receptor
GB0108143D0 (en) * 2001-03-31 2001-05-23 Univ Dundee High-throughput screen
US7393934B2 (en) 2001-12-21 2008-07-01 Human Genome Sciences, Inc. Human G-protein chemokine receptor (CCR5) HDGNR10
EP1463759B8 (de) 2002-01-07 2013-07-10 Euroscreen S.A. Ligand für den g-protein gekoppelten rezeptor gpr43 und seine verwendungen
CA2505316C (en) 2002-11-08 2014-08-05 Ablynx N.V. Single domain antibodies directed against tumour necrosis factor-alpha and uses therefor
WO2005044858A1 (en) 2003-11-07 2005-05-19 Ablynx N.V. Camelidae single domain antibodies vhh directed against epidermal growth factor receptor and uses therefor
GB0228139D0 (en) * 2002-12-03 2003-01-08 Kozlova Zwinderman Olga Fungal biosensor for contaminant detection
EP1587838B1 (de) 2003-01-10 2015-04-15 Ablynx N.V. Therapeutische polypeptide, deren homologe, deren fragmente und deren verwendung bei der modulierung der thrombozytenvermittelten aggregation
WO2005105841A2 (en) 2004-03-12 2005-11-10 Human Genome Sciences, Inc. Human g-protein chemokine receptor (ccr5) hdgnr10
ITMI20040598A1 (it) * 2004-03-26 2004-06-26 Carlotta Giorgi Metodo per la rilevazione di parametri intracellulari con sonde proteiche luminescenti per lo screening di molecole in grado di alterare detti parametri
CA2504920C (en) 2004-05-14 2014-04-01 Euroscreen S.A. Ligand for g-protein coupled receptor fprl2 and uses thereof
WO2006122787A1 (en) 2005-05-18 2006-11-23 Ablynx Nv Serum albumin binding proteins
ES2852423T3 (es) 2005-05-20 2021-09-13 Ablynx Nv NanobodiesTM mejorados para el tratamiento de trastornos mediados por agregación
WO2007100618A2 (en) * 2006-02-23 2007-09-07 Atto Bioscience Novel cell-based phosphodiesterase assays
US20080287371A1 (en) * 2007-05-17 2008-11-20 Tranzyme Pharma Inc. Macrocyclic antagonists of the motilin receptor for modulation of the migrating motor complex
CN102666574A (zh) * 2009-07-14 2012-09-12 Emd密理博公司 具有增加的钙亲和性及增强的生物发光的修饰的发光蛋白及其应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5422266A (en) 1984-12-31 1995-06-06 University Of Georgia Research Foundation, Inc. Recombinant DNA vectors capable of expressing apoaequorin
JPH01285196A (ja) 1988-05-11 1989-11-16 Chisso Corp 発光蛋白エクオリンの製造法
JPH02253162A (ja) † 1989-03-27 1990-10-11 Chisso Corp 特異的結合能を有する物質と結合したエクオリンを用いる検出法
DE68922971T2 (de) † 1988-12-06 1995-10-19 Chisso Corp Mit einem Protein mit spezifischer Bindungsaktivität fusioniertes Aequorin, seine Herstellung, Reinigung und Nachweismethode.
JPH03153700A (ja) † 1989-11-09 1991-07-01 Chisso Corp 物理吸着法により担体に固定化されたエクオリン活性を示す蛋白質
US5714666A (en) 1993-02-09 1998-02-03 Children's Hospital Of Philadelphia Measurement of intracellular calcium using bioluminescent apoaequorin expressed in mammalian cells
US5744320A (en) † 1995-06-07 1998-04-28 Promega Corporation Quenching reagents and assays for enzyme-mediated luminescence

Also Published As

Publication number Publication date
DK1145002T3 (da) 2003-05-05
DK1145002T4 (da) 2009-03-16
EP1145002B1 (de) 2003-02-05
EP1145002A2 (de) 2001-10-17
CA2336929C (en) 2005-10-04
DE69905291T2 (de) 2003-11-06
CA2336929A1 (en) 2000-01-13
DE69905291T3 (de) 2009-06-25
DE69905291D1 (de) 2003-03-13
ES2192060T5 (es) 2009-05-01
JP2002519699A (ja) 2002-07-02
EP1145002B2 (de) 2008-12-10
ES2192060T3 (es) 2003-09-16
WO2000002045A3 (en) 2001-11-08
JP3495987B2 (ja) 2004-02-09
US6872538B1 (en) 2005-03-29
WO2000002045A2 (en) 2000-01-13

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