ATE362550T1 - Verfahren zur identifizierung von hiv rt- dimerisation-inhibitoren - Google Patents

Verfahren zur identifizierung von hiv rt- dimerisation-inhibitoren

Info

Publication number
ATE362550T1
ATE362550T1 AT02750730T AT02750730T ATE362550T1 AT E362550 T1 ATE362550 T1 AT E362550T1 AT 02750730 T AT02750730 T AT 02750730T AT 02750730 T AT02750730 T AT 02750730T AT E362550 T1 ATE362550 T1 AT E362550T1
Authority
AT
Austria
Prior art keywords
subunits
complex
measuring
test compound
hiv
Prior art date
Application number
AT02750730T
Other languages
English (en)
Inventor
Nicolas Sluis-Cremer
Michael Parniak
Alex Pelletier
Original Assignee
Boehringer Ingelheim Ca Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Ca Ltd filed Critical Boehringer Ingelheim Ca Ltd
Application granted granted Critical
Publication of ATE362550T1 publication Critical patent/ATE362550T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/48Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving transferase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/91Transferases (2.)
    • G01N2333/912Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • G01N2333/91205Phosphotransferases in general
    • G01N2333/91245Nucleotidyltransferases (2.7.7)
    • G01N2333/9125Nucleotidyltransferases (2.7.7) with a definite EC number (2.7.7.-)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value
    • G01N2500/02Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT02750730T 2001-07-27 2002-07-26 Verfahren zur identifizierung von hiv rt- dimerisation-inhibitoren ATE362550T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30788301P 2001-07-27 2001-07-27

Publications (1)

Publication Number Publication Date
ATE362550T1 true ATE362550T1 (de) 2007-06-15

Family

ID=23191565

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02750730T ATE362550T1 (de) 2001-07-27 2002-07-26 Verfahren zur identifizierung von hiv rt- dimerisation-inhibitoren

Country Status (10)

Country Link
US (1) US6811970B2 (de)
EP (1) EP1415006B1 (de)
JP (1) JP4409287B2 (de)
AT (1) ATE362550T1 (de)
AU (1) AU2002355761A1 (de)
CA (1) CA2450871C (de)
DE (1) DE60220168T2 (de)
DK (1) DK1415006T3 (de)
ES (1) ES2284893T3 (de)
WO (1) WO2003012127A2 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008156720A1 (en) * 2007-06-14 2008-12-24 Monogram Biosciences, Inc. Electrophoretic tag-based in vitro assay to quantify dimerization of p66 and p51 subunits of hiv-1 reverse transcriptase (rt)
JP2016052799A (ja) * 2016-01-21 2016-04-14 大日本印刷株式会社 生体分子印刷物、及びその製造方法
US11614445B2 (en) 2016-06-09 2023-03-28 Radiometer Turku Oy Background blockers for binding assays

Also Published As

Publication number Publication date
US20030087379A1 (en) 2003-05-08
DK1415006T3 (da) 2007-09-10
AU2002355761A1 (en) 2003-02-17
DE60220168T2 (de) 2008-01-17
CA2450871C (en) 2010-09-07
EP1415006A2 (de) 2004-05-06
US6811970B2 (en) 2004-11-02
ES2284893T3 (es) 2007-11-16
JP2004535832A (ja) 2004-12-02
EP1415006B1 (de) 2007-05-16
JP4409287B2 (ja) 2010-02-03
DE60220168D1 (de) 2007-06-28
CA2450871A1 (en) 2003-02-13
WO2003012127A2 (en) 2003-02-13
WO2003012127A3 (en) 2003-10-16

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