ATE41677T1 - Verfahren zum exprimieren eines gens. - Google Patents

Verfahren zum exprimieren eines gens.

Info

Publication number
ATE41677T1
ATE41677T1 AT82112072T AT82112072T ATE41677T1 AT E41677 T1 ATE41677 T1 AT E41677T1 AT 82112072 T AT82112072 T AT 82112072T AT 82112072 T AT82112072 T AT 82112072T AT E41677 T1 ATE41677 T1 AT E41677T1
Authority
AT
Austria
Prior art keywords
gene
expressing
dna
culturing
foreign
Prior art date
Application number
AT82112072T
Other languages
English (en)
Inventor
Ryoichi Katsumata
Akio Ozaki
Toru Mizukami
Motoko Kageyama
Morimasa Yagisawa
Tamio Mizukami
Seiga Itoh
Tetsuo Oka
Akira Furuya
Original Assignee
Kyowa Hakko Kogyo Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=16613637&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE41677(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kyowa Hakko Kogyo Kk filed Critical Kyowa Hakko Kogyo Kk
Application granted granted Critical
Publication of ATE41677T1 publication Critical patent/ATE41677T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/77—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Corynebacterium; for Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT82112072T 1981-12-29 1982-12-28 Verfahren zum exprimieren eines gens. ATE41677T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP56211908A JPS58126789A (ja) 1981-12-29 1981-12-29 レースレオニンの製造法
EP82112072A EP0088166B2 (de) 1981-12-29 1982-12-28 Verfahren zum Exprimieren eines Gens

Publications (1)

Publication Number Publication Date
ATE41677T1 true ATE41677T1 (de) 1989-04-15

Family

ID=16613637

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82112072T ATE41677T1 (de) 1981-12-29 1982-12-28 Verfahren zum exprimieren eines gens.

Country Status (9)

Country Link
EP (1) EP0088166B2 (de)
JP (1) JPS58126789A (de)
AT (1) ATE41677T1 (de)
AU (1) AU557228B2 (de)
CA (1) CA1202257A (de)
DE (2) DE3279568D1 (de)
ES (1) ES8404409A1 (de)
IL (1) IL67614A (de)
MX (1) MX174306B (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0691827B2 (ja) * 1981-12-17 1994-11-16 協和醗酵工業株式会社 新規ベクタ−プラスミド
JPS6066989A (ja) * 1983-09-24 1985-04-17 Kyowa Hakko Kogyo Co Ltd Ｌ−アルギニンの製造法
JPS59156294A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
EP0334391B1 (de) * 1983-02-17 1993-05-12 Kyowa Hakko Kogyo Co., Ltd. Verfahren zur Herstellung von L-Isoleucin
JPS59156292A (ja) * 1983-02-17 1984-09-05 Kyowa Hakko Kogyo Co Ltd トリプトフアンの製造法
JPH0732710B2 (ja) * 1983-05-28 1995-04-12 協和醗酵工業株式会社 フエニ−ルアラニンの製造法
JPH0783714B2 (ja) * 1983-08-29 1995-09-13 味の素株式会社 発酵法によるｌ―アミノ酸の製造法
JPS6062982A (ja) * 1983-09-14 1985-04-11 Ajinomoto Co Inc 組換えｄνａ，該組換えｄνａを有する細菌及び該細菌を用いるｌ−スレオニン又はｌ−イソロイシンの製造法
JPS6062983A (ja) * 1983-09-14 1985-04-11 Ajinomoto Co Inc 発酵法によるｌ―ヒスチジンの製造法
JPS6066984A (ja) * 1983-09-22 1985-04-17 Ajinomoto Co Inc 発酵法によるｌ−フェニルアラニンの製造法
JPS60210994A (ja) * 1984-04-06 1985-10-23 Kyowa Hakko Kogyo Co Ltd ヒスチジンの製造法
CA1277931C (en) * 1984-06-05 1990-12-18 Shimon Ulitzur Detection and/or identification of microorganisms in a test sample usingbioluminescence or other exogenous genetically-introduced marker
JPH06102029B2 (ja) * 1984-07-31 1994-12-14 味の素株式会社 Ｌ−トリプトフアンの製造法
GB2165546B (en) * 1984-08-21 1989-05-17 Asahi Chemical Ind A plasmid containing a gene for tetracycline resistance and dna fragments derived therefrom
JPH0746994B2 (ja) * 1984-10-04 1995-05-24 味の素株式会社 発酵法によるｌ−アミノ酸の製造法
JPH0655149B2 (ja) * 1985-03-12 1994-07-27 協和醗酵工業株式会社 Ｌ―リジンの製造法
JPS6236196A (ja) * 1985-04-15 1987-02-17 Ajinomoto Co Inc アラニンの製造法
JPS6255089A (ja) * 1985-05-10 1987-03-10 Asahi Chem Ind Co Ltd ホスホエノ−ルピルビン酸カルボキシラ−ゼ産生遺伝子を含むｄｎａ断片
DE204326T1 (de) * 1985-06-05 1987-07-02 Kyowa Hakko Kogyo Co., Ltd., Tokio/Tokyo Verfahren zur herstellung von l-threonin und l-isoleucin.
JPH06102028B2 (ja) * 1985-10-04 1994-12-14 協和醗酵工業株式会社 アミノ酸の製造法
FR2590592B1 (fr) * 1985-11-26 1989-12-22 Asahi Chemical Ind Fragment d'adn contenant un gene codant pour une enzyme catalysant une reaction dans le cycle tca et adn recombinant le contenant.
US4920054A (en) * 1986-07-25 1990-04-24 Allelix, Inc. Shuttle vectors from rhodococcus equi
JPS63273469A (ja) * 1986-12-13 1988-11-10 Kyowa Hakko Kogyo Co Ltd 乳糖資化性を有する新規微生物
WO1988009819A2 (en) * 1987-06-12 1988-12-15 Massachusetts Institute Of Technology C. glutamicum threonine biosynthetic pathway
US6649379B1 (en) 1987-06-12 2003-11-18 Massachusetts Institute Of Technology Method and deregulated enzyme for threonine production
US5153123A (en) * 1987-10-15 1992-10-06 Mitsubishi Petrochemical Co., Ltd. Method for producing l-threonine, and plasmid and microorganism employed in the same
DE3908201A1 (de) * 1989-03-14 1990-09-27 Degussa Verfahren zur fermentativen herstellung von l-lysin
FR2747131B1 (fr) * 1996-04-09 1998-06-26 Orsan Procede de production d'amino acide par fermentation de corynebacterie exprimant une activite trehalase
DE19912384A1 (de) * 1999-03-19 2000-09-21 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
DE19924364A1 (de) * 1999-05-27 2000-11-30 Degussa Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
US6586214B1 (en) 1999-09-15 2003-07-01 Degussa Ag Method for increasing the metabolic flux through the pentose phosphate cycle in coryneform bacteria by regulation of the phosphoglucose isomerase (pgi gene)
US7368266B2 (en) 2001-02-13 2008-05-06 Cj Corporation Method for L-threonine production
DK1831349T3 (da) 2004-12-06 2012-01-23 Sage Biosciences Inc Fremgangsmåde til dyrkning af bakterier til afgivelse af bioaktive forbindelser til tarmen af drøvtyggere

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2076853B (en) * 1980-04-17 1983-12-21 Ajinomoto Kk L-glutamic acid producing microorganisms
JPS56160997A (en) * 1980-05-16 1981-12-11 Ajinomoto Co Inc Preparation of l-lysine by fermenaition method
JPS56148296A (en) * 1980-04-17 1981-11-17 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation method
JPS56148295A (en) * 1980-04-17 1981-11-17 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation method
JPS57134500A (en) * 1981-02-12 1982-08-19 Kyowa Hakko Kogyo Co Ltd Plasmid pcg1
JPS57183799A (en) * 1981-04-17 1982-11-12 Kyowa Hakko Kogyo Co Ltd Novel plasmid
JPS57186496A (en) * 1981-05-11 1982-11-16 Ajinomoto Co Inc Preparation of l-threonine by fermentation
JPS58893A (ja) * 1981-06-25 1983-01-06 Ajinomoto Co Inc 発酵法によるｌ−イソロイシンの製造法
JPS5835197A (ja) * 1981-08-26 1983-03-01 Kyowa Hakko Kogyo Co Ltd プラスミドｐｃｇ２
JPS5867699A (ja) * 1981-10-16 1983-04-22 Ajinomoto Co Inc プラスミド
JPH0691827B2 (ja) * 1981-12-17 1994-11-16 協和醗酵工業株式会社 新規ベクタ−プラスミド
ES8406544A1 (es) * 1982-05-04 1984-07-16 Ajinomoto Kk Procedimiento para preparar un plasmido compuesto.

Also Published As

Publication number Publication date
EP0088166B1 (de) 1989-03-22
CA1202257A (en) 1986-03-25
JPS58126789A (ja) 1983-07-28
AU9191982A (en) 1983-07-07
AU557228B2 (en) 1986-12-11
ES518665A0 (es) 1984-04-16
IL67614A (en) 1990-11-29
ES8404409A1 (es) 1984-04-16
EP0088166B2 (de) 1997-06-25
EP0088166A3 (en) 1984-04-25
MX174306B (es) 1994-05-04
IL67614A0 (en) 1983-05-15
JPH0138475B2 (de) 1989-08-14
EP0088166A2 (de) 1983-09-14
DE88166T1 (de) 1984-03-15
DE3279568D1 (en) 1989-04-27

Similar Documents

Publication Publication Date Title
ATE41677T1 (de) Verfahren zum exprimieren eines gens.
IL55890A (en) Method and means for polypeptide production involving expression of a heterologous gene,and as products therefrom recombinant microbial cloning vehicles containing said gene
ES518348A0 (es) Un plasmido vector recombinante.
FI810722A7 (fi) Menetelmä ja vektoriorganismi, joiden avulla kloonattujen heterologisten geenien tuotteita voidaan valmistaasuuria määriä valvotuissa olosuhteissa Bacillus subtiliksessa.
DE3768431D1 (de) Waessrige schreibfluessigkeiten sowie ein verfahren zu deren herstellung.
DE3484689D1 (de) Die verwendung des gal 1 hefe-promotors.
SE8100713L (sv) Fermentationsforfarande
FR2444713A1 (fr) Procede de production d'un adn comprenant le genome du virus de l'hepatite b et vecteur le comportant
ATE44047T1 (de) Verfahren zur herstellung von interferonen.
ATE177786T1 (de) Herstellungsverfahren für ein plasmid mit fähigkeiten zu expression und prozessierung nach translation eines retroviralen gens, so erhaltenes plasmid und dessen expressionsprodukt
SE7400547L (de)
PT83968A (de) Verfahren zur verbesserung des expression von eukaryontenprotein
ATE118817T1 (de) Verfahren zur herstellung von xbai- restriktionsendonuklease und -methylase.
ATE16943T1 (de) Rekombinanter bakteriophage fuer heterologe klonierung von bazillus-mikroorganismen und verfahren zu seiner herstellung.
ATE106448T1 (de) Verfahren zur herstellung von hinpi- restriktionsendonuklease und -methylase.
BE899661A (fr) Procede d'augmentation de la production d'antibiotique par recombinaison genetique in vivo.
ATE103329T1 (de) Verfahren zur herstellung von hgiairestriktionsendonuklease und -methylase.
DE3877012D1 (de) Verfahren zur regulierten expression eines fremdgens durch kontrolle der kulturtemperatur und ein prozess, dadurch ein fremdgenprodukt herzustellen.
ATE101647T1 (de) Verfahren zur herstellung von aseirestriktionsendonuklease und -methylase.
ES444374A1 (es) Un metodo para producir acido 1(+)-tartarico.
ATE15582T1 (de) Verfahren zum herstellen von rohpoekelware.
ATE60802T1 (de) Mikrobiologisches verfahren zur herstellung von menschlichem lysozym.
KR880010118A (ko) 배지의 당분농도 제어에 의한 외래유전자 발현 제어 방법 및 그에 따른 외래유전자 산물의 생산방법
EP0133550A3 (en) Process for producing arphamenine in high yield
DK240284A (da) Plasmider med betinget ukontrolleret replikationsopfoersel