ATE424458T1 - Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung - Google Patents

Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung

Info

Publication number
ATE424458T1
ATE424458T1 AT01946701T AT01946701T ATE424458T1 AT E424458 T1 ATE424458 T1 AT E424458T1 AT 01946701 T AT01946701 T AT 01946701T AT 01946701 T AT01946701 T AT 01946701T AT E424458 T1 ATE424458 T1 AT E424458T1
Authority
AT
Austria
Prior art keywords
polypeptides
present
methods
vegf
nucleic acids
Prior art date
Application number
AT01946701T
Other languages
English (en)
Inventor
Napoleone Ferrara
Colin Watanabe
William Wood
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/US2000/032678 external-priority patent/WO2001040466A2/en
Application filed by Genentech Inc filed Critical Genentech Inc
Application granted granted Critical
Publication of ATE424458T1 publication Critical patent/ATE424458T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A61K38/1858—Platelet-derived growth factor [PDGF]
    • A61K38/1866—Vascular endothelial growth factor [VEGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/475—Assays involving growth factors
    • G01N2333/515—Angiogenesic factors; Angiogenin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Reproductive Health (AREA)
  • Diabetes (AREA)
AT01946701T 2000-06-23 2001-06-22 Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung ATE424458T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US21363700P 2000-06-23 2000-06-23
US23097800P 2000-09-07 2000-09-07
PCT/US2000/032678 WO2001040466A2 (en) 1999-12-01 2000-12-01 Secreted and transmembrane polypeptides and nucleic acids encoding the same

Publications (1)

Publication Number Publication Date
ATE424458T1 true ATE424458T1 (de) 2009-03-15

Family

ID=26908256

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01946701T ATE424458T1 (de) 2000-06-23 2001-06-22 Eg-vegf nukleinsäuren und polypeptide und verfahren zur deren verwendung

Country Status (13)

Country Link
US (4) US20020172678A1 (de)
EP (2) EP2075334B1 (de)
JP (1) JP5081361B2 (de)
KR (1) KR100871735B1 (de)
CN (2) CN1449445B (de)
AT (1) ATE424458T1 (de)
AU (3) AU6871401A (de)
CA (1) CA2412612C (de)
DE (1) DE60137847D1 (de)
DK (1) DK1294876T3 (de)
ES (1) ES2323569T3 (de)
MX (1) MXPA03000150A (de)
WO (1) WO2002000711A2 (de)

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US7264801B2 (en) * 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US6485938B1 (en) * 1999-11-16 2002-11-26 Zymogenetics, Inc. Nucleic acid molecules that encodes human Zven1
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US20050271663A1 (en) * 2001-06-28 2005-12-08 Domantis Limited Compositions and methods for treating inflammatory disorders
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CA2481724A1 (en) 2002-04-15 2003-10-30 The Regents Of The University Of California Screening and therapeutic methods for treating circadian rhythm disorders
DE10229379A1 (de) * 2002-06-26 2004-01-29 Schering Ag EG-VEGF Rezeptor Antagonisten
US7696320B2 (en) 2004-08-24 2010-04-13 Domantis Limited Ligands that have binding specificity for VEGF and/or EGFR and methods of use therefor
US9321832B2 (en) * 2002-06-28 2016-04-26 Domantis Limited Ligand
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KR100781753B1 (ko) * 2006-05-24 2007-12-04 연세대학교 산학협력단 Ｄｋｋ2를 포함하는 혈관신생을 촉진시키는 방법
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WO2014201283A1 (en) * 2013-06-12 2014-12-18 The Regents Of The University Of California Methods for protecting ovarian function
JP6320040B2 (ja) * 2013-12-27 2018-05-09 国立大学法人福井大学 抗ｐｒｏｋ１抗体及び抗ｖｅｇｆ抗体併用による大腸癌の治療
JP2015127307A (ja) * 2013-12-27 2015-07-09 国立大学法人福井大学 抗ｐｒｏｋ１抗体による大腸癌の治療
WO2018111913A1 (en) * 2016-12-12 2018-06-21 Gi Dynamics, Inc. Methods for assessing treatment with a gastrointestinal implant
RU2662944C1 (ru) * 2017-02-17 2018-07-31 Общество с ограниченной ответственностью "Группа развития "АПЕКС" Средство для лечения состояний человеческого организма, связанных с уменьшением уровня экспрессии гена prok 1 и/или уменьшением количества белка прокинетицина 1 на основе генно-терапевтических субстанций с геном prok 1, способ получения и использования
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US7446168B2 (en) 2008-11-04
JP5081361B2 (ja) 2012-11-28
DE60137847D1 (de) 2009-04-16
AU2001268714B2 (en) 2006-09-21
KR20030011104A (ko) 2003-02-06
US20020172678A1 (en) 2002-11-21
KR100871735B1 (ko) 2008-12-03
US20070122412A1 (en) 2007-05-31
CN1449445A (zh) 2003-10-15
AU6871401A (en) 2002-01-08
US20100254999A1 (en) 2010-10-07
US8557238B2 (en) 2013-10-15
EP1294876B1 (de) 2009-03-04
AU2006252241B2 (en) 2010-03-04
MXPA03000150A (es) 2003-09-22
CN101269214A (zh) 2008-09-24
HK1059452A1 (en) 2004-07-02
JP2004511432A (ja) 2004-04-15
US7727536B2 (en) 2010-06-01
HK1132298A1 (en) 2010-02-19
ES2323569T3 (es) 2009-07-21
DK1294876T3 (da) 2009-06-02
CN1449445B (zh) 2012-07-18
AU2006252241A1 (en) 2007-01-25
EP2075334B1 (de) 2013-11-20
WO2002000711A2 (en) 2002-01-03
EP1294876A2 (de) 2003-03-26
US20050064522A1 (en) 2005-03-24
WO2002000711A3 (en) 2002-06-20
CN101269214B (zh) 2013-09-04
CA2412612A1 (en) 2002-01-03
EP2075334A1 (de) 2009-07-01
CA2412612C (en) 2013-04-30

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