ATE491788T1 - Proteasevarianten - Google Patents

Proteasevarianten

Info

Publication number
ATE491788T1
ATE491788T1 AT04762907T AT04762907T ATE491788T1 AT E491788 T1 ATE491788 T1 AT E491788T1 AT 04762907 T AT04762907 T AT 04762907T AT 04762907 T AT04762907 T AT 04762907T AT E491788 T1 ATE491788 T1 AT E491788T1
Authority
AT
Austria
Prior art keywords
variants
protease
relates
methods
well
Prior art date
Application number
AT04762907T
Other languages
English (en)
Inventor
Maria Leonardo De
Carsten Andersen
Lars Christensen
Soren Lassen
Peter Rahbek Ystergaard
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE491788T1 publication Critical patent/ATE491788T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/189—Enzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/11—Antisense
    • C12N2310/111—Antisense spanning the whole gene, or a large part of it

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Polymers & Plastics (AREA)
  • Mycology (AREA)
  • Food Science & Technology (AREA)
  • Animal Husbandry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Fodder In General (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Chemical Or Physical Treatment Of Fibers (AREA)
AT04762907T 2003-10-10 2004-10-08 Proteasevarianten ATE491788T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DKPA200301494 2003-10-10
DKPA200400333 2004-03-01
PCT/DK2004/000688 WO2005035747A1 (en) 2003-10-10 2004-10-08 Protease variants

Publications (1)

Publication Number Publication Date
ATE491788T1 true ATE491788T1 (de) 2011-01-15

Family

ID=34436496

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04762907T ATE491788T1 (de) 2003-10-10 2004-10-08 Proteasevarianten

Country Status (11)

Country Link
US (4) US7892808B2 (de)
EP (3) EP2284259A3 (de)
JP (2) JP2007509603A (de)
CN (1) CN1867668A (de)
AT (1) ATE491788T1 (de)
AU (1) AU2004279924B2 (de)
BR (1) BRPI0414959A (de)
CA (1) CA2539693A1 (de)
DE (1) DE602004030595D1 (de)
ES (1) ES2358092T3 (de)
WO (1) WO2005035747A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2291883T3 (es) * 2003-02-07 2008-03-01 Novozymes A/S Proteasas.
US20060236414A1 (en) * 2003-06-19 2006-10-19 Novozymes A/S Proteases and methods for producing them
EP2284259A3 (de) * 2003-10-10 2011-06-15 Novozymes A/S Proteasen
CA2586222A1 (en) 2004-05-24 2005-12-08 Novozymes A/S Enzymes for pharmaceutical use
CA2591858C (en) * 2004-06-21 2015-05-05 Novozymes A/S Proteases derived from norcardiopsis
EP2043454B1 (de) 2006-07-13 2016-05-04 DSM IP Assets B.V. Verwendung von bakteriellen amylasen in futter für rinder
CA2670731C (en) * 2006-12-22 2017-11-28 Novozymes A/S Method for producing a yeast extract
CN101889084A (zh) * 2007-12-04 2010-11-17 诺维信公司 供药学应用的蛋白酶变体
WO2009140481A1 (en) 2008-05-14 2009-11-19 Novozymes A/S Liquid detergent compositions
MX2011007101A (es) 2008-12-31 2011-08-04 Solae Llc Composiciones de hidrolizados proteicos que tienen capacidad mejorada para liberar colecistocinina (cck).
AU2011231563B2 (en) * 2010-03-26 2015-01-29 Novozymes A/S Thermostable phytase variants
AU2011319755B2 (en) 2010-10-27 2017-02-23 President And Fellows Of Harvard College Compositions of toehold primer duplexes and methods of use
US20130331315A1 (en) 2011-02-23 2013-12-12 Solae, Llc Protein Hydrolysate Compositions Having Enhanced CCK and GLP-1 Releasing Activity
ES2641039T3 (es) 2011-08-19 2017-11-07 Novozymes A/S Polipéptidos con actividad de proteasa
ES2628190T3 (es) 2011-09-22 2017-08-02 Novozymes A/S Polipéptidos con actividad de proteasa y polinucleótidos que codifican los mismos
AU2012360992B2 (en) 2011-12-28 2018-08-09 Novozymes A/S Polypeptides having protease activity
MX2014008764A (es) 2012-01-26 2014-08-27 Novozymes As Uso de polipeptidos que tienen actividad proteasa en alimentos para animales y detergentes.
BR112014031882A2 (pt) 2012-06-20 2017-08-01 Novozymes As uso de um polipeptídeo isolado, polipeptídeo, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira de expressão recombinante, métodos para produção de um polipeptídeo, para melhoria do valor nutricional de uma ração animal, e para o tratamento de proteínas, uso de pelo menos um polipeptídeo, aditivo de ração animal, ração animal, e, composição detergente
AU2013311668B2 (en) 2012-09-05 2019-02-28 Novozymes A/S Polypeptides having protease activity
US9872937B2 (en) 2012-09-19 2018-01-23 Microvascular Tissues, Inc. Compositions and methods for treating and preventing tissue injury and disease
US9551042B2 (en) 2012-12-21 2017-01-24 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
US9441215B2 (en) 2013-02-06 2016-09-13 Novozymes A/S Polypeptides having protease activity
EP3215615B1 (de) 2014-11-04 2025-05-21 Novozymes A/S Polypeptide mit serinproteaseaktivität und polynukleotide zur codierung davon und deren anwendung in futtermitteln
EP3974537A1 (de) * 2015-01-30 2022-03-30 President and Fellows of Harvard College Mikroskopfreie bildgebung
DE102016204814A1 (de) * 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Verbesserte Reinigungsleistung an Protein sensitiven Anschmutzungen
DE102016204815A1 (de) * 2016-03-23 2017-09-28 Henkel Ag & Co. Kgaa Proteasen mit verbesserte Enzymstabilität in Waschmittel
US11492661B2 (en) 2017-01-10 2022-11-08 President And Fellows Of Harvard College Multiplexed signal amplification
WO2018169780A1 (en) 2017-03-15 2018-09-20 Dupont Nutrition Biosciences Aps Methods of using an archaeal serine protease
EP3743525A4 (de) 2018-01-26 2021-09-29 President and Fellows of Harvard College Näherungsdetektionsverfahren und -zusammensetzungen
AU2019240244A1 (en) 2018-03-22 2020-11-19 President And Fellows Of Harvard College Methods and compositions for molecular authentication
CN110727780A (zh) * 2019-10-17 2020-01-24 福建天晴数码有限公司 一种相识文本自动扩展的系统及其方法
CN115074345B (zh) * 2021-03-10 2024-04-05 中国农业科学院农业资源与农业区划研究所 耐热β-1,4-内切木聚糖酶及其编码基因与应用
US20250311734A1 (en) 2022-05-14 2025-10-09 Novozymes A/S Compositions and Methods for Preventing, Treating, Suppressing and/or Eliminatting Phytopathogenic Infestations and Infections
CN115772531B (zh) * 2022-11-11 2024-11-12 吉林农业大学 一种果胶酸裂解酶基因突变体及其克隆方法和应用
CN116103264B (zh) * 2022-12-28 2025-05-09 厦门蓝湾科技有限公司 一种提高磷脂酶d合成ps活性的理性定向进化方法

Family Cites Families (143)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2723250A (en) * 1953-05-05 1955-11-08 Petrolite Corp Oxyalkylated derivatives of fusible acetylene-phenolic resins
GB1234445A (de) * 1967-10-03 1971-06-03
GB1296839A (de) 1969-05-29 1972-11-22
DE2004328C3 (de) 1970-01-30 1979-10-18 Nippon Kokan K.K., Tokio Bodenkonstruktion für eine Gas-Flüssigkeits-Kontaktierkolonne
US3823072A (en) * 1970-02-19 1974-07-09 M Hooreman Analysis of proteolytic enzymes
US3683069A (en) * 1970-02-19 1972-08-08 Michel Hooreman Enzymatic products which optimize the viscosity of mucuses and their applications
GB1372034A (en) 1970-12-31 1974-10-30 Unilever Ltd Detergent compositions
GB1483591A (en) 1973-07-23 1977-08-24 Novo Industri As Process for coating water soluble or water dispersible particles by means of the fluid bed technique
US3868448A (en) * 1973-12-07 1975-02-25 Grace W R & Co Method for bloat control
US3966971A (en) * 1975-01-02 1976-06-29 Grain Processing Corporation Separation of protein from vegetable sources
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
US4073884A (en) * 1976-09-27 1978-02-14 W. R. Grace & Co. Promotion of feed efficiency
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
DE3132936A1 (de) 1981-08-20 1983-03-03 Henkel KGaA, 4000 Düsseldorf "verfahren zur herstellung saurer protease und diese bildende mutanten der gattung rhizopus"
DD200432A1 (de) 1981-09-08 1983-05-04 Werner Fleck Verfahren zur herstellung eines proteolytischen enzym-praeparates
DE3149457A1 (de) * 1981-12-14 1983-06-23 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung saurer protease und diese bildende mutanten von pilzen der gattung aspergillus
NZ208612A (en) 1983-06-24 1991-09-25 Genentech Inc Method of producing "procaryotic carbonyl hydrolases" containing predetermined, site specific mutations
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
WO1987000859A1 (en) 1985-08-09 1987-02-12 Gist-Brocades N.V. Novel lipolytic enzymes and their use in detergent compositions
CA1295566C (en) 1987-07-21 1992-02-11 Robert T. Garvin Characterization and structure of genes for protease a and protease b from streptomyces griseus
EG18543A (en) 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
FR2600340A1 (fr) * 1986-06-20 1987-12-24 Hooremam Michel Procede de production d'un nouveau complexe proteolytique stimulant l'activite du pancreas et ses applications en zootechnie
EP0258068B1 (de) 1986-08-29 1994-08-31 Novo Nordisk A/S Enzymhaltiger Reinigungsmittelzusatz
NZ221627A (en) 1986-09-09 1993-04-28 Genencor Inc Preparation of enzymes, modifications, catalytic triads to alter ratios or transesterification/hydrolysis ratios
DK564086A (da) * 1986-11-25 1988-06-17 Novo Industri As Enzymatisk detergent-additiv
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
JPS6474992A (en) 1987-09-16 1989-03-20 Fuji Oil Co Ltd Dna sequence, plasmid and production of lipase
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体dna、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
JP2728531B2 (ja) 1988-03-24 1998-03-18 ノボ ノルディスク アクティーゼルスカブ セルラーゼ調製品
US5648263A (en) 1988-03-24 1997-07-15 Novo Nordisk A/S Methods for reducing the harshness of a cotton-containing fabric
JPH02255081A (ja) 1989-03-30 1990-10-15 Snow Brand Milk Prod Co Ltd プロテアーゼ生産菌、該菌体から産生したプロテアーゼ、及びその精製方法
DK316989D0 (da) 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
EP0509985B1 (de) 1990-01-11 1994-04-13 Novo Nordisk A/S Aus einem nocardiopsis-stamm stammendes bakteriolytisches enzym, seine herstellung und verwendung
IL97645A (en) 1990-03-23 1997-03-18 Gist Brocades Nv Production of enzymes in seeds and their use
DK0528828T4 (da) 1990-04-14 1998-08-31 Genencor Internat Gmbh Alkaliske bacillus-lipaser, DNA-sekvenser, der koder herfor, og bacilli der producerer sådanne lipaser
CA2082279C (en) 1990-05-09 2007-09-04 Grethe Rasmussen Cellulase preparation comprising an endoglucanase enzyme
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
DK0548228T3 (da) 1990-09-13 1999-05-10 Novo Nordisk As Lipasevarianter
CA2095852C (en) 1990-12-05 2001-05-08 Uffe Lovborg Proteins with changed epitopes and methods for the production thereof
DK0563169T3 (da) 1990-12-21 1998-05-18 Novo Nordisk As Enzymmutanter med lille variation i molekylær ladning i et pH område
DE69133035T2 (de) 1991-01-16 2003-02-13 The Procter & Gamble Company, Cincinnati Kompakte Waschmittelzusammensetzungen mit hochaktiven Cellulasen
CA2063892A1 (en) 1991-03-29 1992-09-30 Susan A. Anderson Alpha-lytic protease cleaning compositions
AU666660B2 (en) 1991-04-30 1996-02-22 Procter & Gamble Company, The Built liquid detergents with boric-polyol complex to inhibit proteolytic enzyme
EP0511456A1 (de) 1991-04-30 1992-11-04 The Procter & Gamble Company Flüssiges Reinigungsmittel mit einem aromatischen Boratester zur Inhibierung des proteolytischen Enzyms
ES2090481T3 (es) 1991-05-01 1996-10-16 Unilever Nv Composiciones detergentes que contienen enzimas estabilizadas.
ES2121014T3 (es) 1991-05-01 1998-11-16 Novo Nordisk As Enzimas estabilizadas y composiciones detergentes.
US5646028A (en) * 1991-06-18 1997-07-08 The Clorox Company Alkaline serine protease streptomyces griseus var. alkaliphus having enhanced stability against urea or guanidine
US5811382A (en) * 1991-12-20 1998-09-22 Novo Nordisk A/S Detergent compositions
JP3396033B2 (ja) 1992-05-19 2003-04-14 塩野義製薬株式会社 新規プロテアーゼ
DK72992D0 (da) 1992-06-01 1992-06-01 Novo Nordisk As Enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
DK91192D0 (da) 1992-07-10 1992-07-10 Novo Nordisk As Protein
KR100294361B1 (ko) 1992-07-23 2001-09-17 피아 스타르 돌연변이체알파-아밀라제,세정제,접시세척제,및액화제
US5792641A (en) 1992-10-06 1998-08-11 Novo Nordisk A/S Cellulase variants and detergent compositions containing cellulase variants
HU219675B (hu) 1993-02-11 2001-06-28 Genencor International Inc. Oxidatívan stabil alfa-amiláz
DE69434242T2 (de) 1993-04-27 2006-01-12 Genencor International, Inc., Palo Alto Neuartige Lipasevarianten zur Verwendung in Reinigungsmitteln
DK81193D0 (da) 1993-07-06 1993-07-06 Novo Nordisk As Enzym
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
CA2173329C (en) 1993-10-08 2011-07-12 Henrik Bisgard-Frantzen Amylase variants
EP0724631A1 (de) 1993-10-13 1996-08-07 Novo Nordisk A/S H 2?o 2?-stabile peroxidasevarianten
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
AU1911995A (en) 1994-02-14 1995-08-29 Quaker Oats Company, The Animal food palatability improving composition and process
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
MX9603542A (es) 1994-02-22 1997-03-29 Novo Nordisk As Metodo para preparar una variante de una enzima lipolitica.
DE69536145D1 (de) 1994-03-08 2011-04-07 Novozymes As Neuartige alkalische Zellulasen
US5689054A (en) 1994-03-17 1997-11-18 The United States Of America As Represented By The Secretary Of Agriculture Low phytic acid mutants and selection thereof
CA2186592C (en) 1994-03-29 2008-02-19 Helle Outtrup Alkaline bacillus amylase
EP1142485B1 (de) 1994-04-22 2008-02-27 Novozymes A/S Verfahren zur Verbesserung von der Löslichkeit von pflanzlichen Proteinen
WO1995030744A2 (en) 1994-05-04 1995-11-16 Genencor International Inc. Lipases with improved surfactant resistance
AU2884595A (en) 1994-06-20 1996-01-15 Unilever Plc Modified pseudomonas lipases and their use
AU2884695A (en) 1994-06-23 1996-01-19 Unilever Plc Modified pseudomonas lipases and their use
DE4422198C2 (de) 1994-06-24 1997-08-28 Audi Ag Verfahren zum Steuern der elektrischen Beheizung eines Katalysators
GB9416841D0 (en) 1994-08-19 1994-10-12 Finnfeeds Int Ltd An enzyme feed additive and animal feed including it
US5919691A (en) 1994-10-06 1999-07-06 Novo Nordisk A/S Enzyme and enzyme preparation with endoglucanase activity
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
CN1167503A (zh) 1994-10-26 1997-12-10 诺沃挪第克公司 一种具有脂解活性的酶
AU3924095A (en) 1994-11-24 1996-06-17 Novo Nordisk A/S A process for producing polypeptides with reduced allergenicity
AU697440B2 (en) 1994-12-07 1998-10-08 Novozymes A/S Polypeptide with reduced allergenicity
US5877403A (en) * 1994-12-30 1999-03-02 Seminis Vegetable Seeds, Inc. Papaya ringspot virus protease gene
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
CN1182451A (zh) 1995-03-17 1998-05-20 诺沃挪第克公司 新的内切葡聚糖酶
EP0839186B1 (de) 1995-07-14 2004-11-10 Novozymes A/S Modifiziertes enzym mit lipolytischer aktivität
JP4068142B2 (ja) 1995-08-11 2008-03-26 ノボザイムス アクティーゼルスカブ 新規の脂肪分解酵素
DK0843725T3 (da) 1995-08-11 2002-08-12 Novozymes As Fremgangmåde til fremstilling af polypeptidvarianter
DK1396A (de) 1996-01-09 1996-01-09 Novo Nordisk As
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
AU3938997A (en) 1996-08-26 1998-03-19 Novo Nordisk A/S A novel endoglucanase
BR9711479B1 (pt) 1996-09-17 2009-08-11 variante de celulase tendo uma resistência aumentada a tensìdeo de ánion.
AU730286B2 (en) 1996-10-08 2001-03-01 Novo Nordisk A/S Diaminobenzoic acid derivatives as dye precursors
US5705379A (en) * 1996-10-23 1998-01-06 Cornell Research Foundation, Inc. Nucleotide sequences encoding a thermostable alkaline protease
EP0948606B1 (de) 1996-12-20 2000-08-02 Novo Nordisk A/S Peniophora phytase
JP2002510963A (ja) 1997-01-10 2002-04-09 ノボザイムス アクティーゼルスカブ スキンケア用酵素修飾体
JP2001511162A (ja) 1997-02-06 2001-08-07 ノボ ノルディスク アクティーゼルスカブ 付加され、そして/又は除去された付着基を有するポリペプチド−ポリマー結合体
DK0996718T3 (da) 1997-03-18 2009-04-06 Novozymes As Fremgangsmåde til konstruktion af et bibliotek ved anvendelse af DNA-shuffling
NZ337910A (en) 1997-03-18 2001-10-26 Novo Nordisk As Shuffling of heterologous DNA sequences using conserved regions
FI972521A7 (fi) 1997-06-13 1998-12-14 Cultor Oy Menetelmä ravinnollisen tuotteen valmistamiseksi ja näin valmistettu tuote
WO1999000489A1 (en) 1997-06-25 1999-01-07 Novo Nordisk A/S A modified polypeptide
EP1002061A1 (de) 1997-07-04 2000-05-24 Novo Nordisk A/S Varianten der 6 endo-1,4-beta-glukanase und diese enthaldende reinigungszusammensetzungen
NZ330940A (en) 1997-07-24 2000-02-28 F Production of consensus phytases from fungal origin using computer programmes
US6835550B1 (en) 1998-04-15 2004-12-28 Genencor International, Inc. Mutant proteins having lower allergenic response in humans and methods for constructing, identifying and producing such proteins
CN1323345A (zh) 1998-10-13 2001-11-21 诺沃奇梅兹有限公司 具有降低的免疫应答的修饰多肽
ATE365210T1 (de) 1998-10-30 2007-07-15 Novozymes As Glykosylierte proteine mit reduzierter allergenität
JP2003500003A (ja) 1998-10-30 2003-01-07 ノボザイムス アクティーゼルスカブ 低いアレルゲン性のタンパク質変異型
ES2532606T3 (es) 1999-03-31 2015-03-30 Novozymes A/S Polipéptidos con actividad de alfa-amilasa alcalina y ácidos nucleicos que los codifican
AU4095800A (en) 1999-04-23 2000-11-10 University Of Guelph Transgenic animals expressing salivary proteins
KR20020077421A (ko) 2000-02-08 2002-10-11 에프. 호프만-라 로슈 아게 동물 사료에서 산-안정성 서브틸리신 프로테아제의 사용
US6855548B2 (en) * 2000-02-08 2005-02-15 F. Hoffman-La Roche Ag Use of acid-stable proteases in animal feed
US6960462B2 (en) * 2000-02-08 2005-11-01 Dsm Ip Assets B.V Use of acid-stable subtilisin proteases in animal feed
EP1263942B1 (de) 2000-03-08 2013-11-06 Novozymes A/S Varianten mit veränderten eigenschaften
CA2406621A1 (en) 2000-04-28 2001-11-08 Novozymes A/S Protein variants having modified immunogenicity
EP1389217B1 (de) 2001-05-04 2008-05-21 Novozymes A/S Antimikrobielles polypeptid
US7630836B2 (en) * 2001-05-30 2009-12-08 The Kitasato Institute Polynucleotides
DE60215534T2 (de) 2001-11-20 2007-09-20 Novozymes A/S Antimikrobielle polypeptide aus pseudoplectania nigrella
AU2002349297A1 (en) 2001-12-03 2003-06-17 Kobenhavns Amt Statin-like compounds
JP4137526B2 (ja) 2002-01-23 2008-08-20 Toto株式会社 ケラチナーゼおよびその製造法
JP4114046B2 (ja) 2002-07-12 2008-07-09 川村通商株式会社 酵素脱毛処理剤および酵素脱毛法
DK175871B1 (da) 2003-01-10 2005-05-02 Pedershaab Concrete Technologi Fremgangsmåde samt apparat til fremstilling af betonrör
WO2004070106A1 (ja) * 2003-02-06 2004-08-19 Daiwa Kasei K.K. 獣毛繊維の防縮加工法
WO2004072279A2 (en) * 2003-02-07 2004-08-26 Novozymes A/S Proteases
ES2291883T3 (es) * 2003-02-07 2008-03-01 Novozymes A/S Proteasas.
US20060236414A1 (en) * 2003-06-19 2006-10-19 Novozymes A/S Proteases and methods for producing them
DE602004027376D1 (de) 2003-06-19 2010-07-08 Novozymes As Proteasen
WO2004111223A1 (en) 2003-06-19 2004-12-23 Novozymes A/S Proteases
WO2004111222A1 (en) 2003-06-19 2004-12-23 Novozymes A/S Proteases
DK1639105T4 (da) * 2003-06-19 2012-12-10 Novozymes As Proteases
CN1836035B (zh) * 2003-06-19 2013-03-20 诺维信公司 改进的蛋白酶及其制备方法
US7208310B2 (en) * 2003-06-19 2007-04-24 Novozymes A/S Proteases
BRPI0413833A (pt) * 2003-09-11 2006-10-24 Novozymes As célula hospedeira microbiana recombinante, construção de ácido nucleico, método para produzir uma enzima e/ou um agente antimicrobiano, produto de fusão, aditivo e composição de ração animal, animal não humano transgênico ou produtos ou elementos deste, usos do produto de fusão, da co-expressão de um agente antimicrobiano e uma enzima, e de um peptìdeo de proteção, e, método para identificar um peptìdeo de proteção
EP2284259A3 (de) * 2003-10-10 2011-06-15 Novozymes A/S Proteasen
CA2586222A1 (en) 2004-05-24 2005-12-08 Novozymes A/S Enzymes for pharmaceutical use
CA2591858C (en) * 2004-06-21 2015-05-05 Novozymes A/S Proteases derived from norcardiopsis
CN101010424A (zh) 2004-06-21 2007-08-01 诺维信公司 生产异源蛋白酶的改进方法
US8420070B2 (en) * 2006-05-22 2013-04-16 Westham Ltd. Controlling sugar feeding insects
CA2670731C (en) * 2006-12-22 2017-11-28 Novozymes A/S Method for producing a yeast extract
US7618801B2 (en) * 2007-10-30 2009-11-17 Danison US Inc. Streptomyces protease
CN101889084A (zh) * 2007-12-04 2010-11-17 诺维信公司 供药学应用的蛋白酶变体
NZ589029A (en) * 2008-06-03 2011-09-30 Novozymes As Method for producing a wheat protein hydrolysate
DK2300606T3 (da) * 2008-06-03 2012-04-16 Novozymes As Fremgangsmåde til fremstilling af et kaseinhydrolysat
CN102387710A (zh) * 2008-06-20 2012-03-21 索莱有限责任公司 在酸性条件下稳定的蛋白质水解产物组合物
US20100093633A1 (en) * 2008-10-10 2010-04-15 Novozymes A/S Polypeptides having antimicrobial activity
CA2773686C (en) * 2009-04-02 2018-01-16 Novozymes A/S Process for making a milk-based protein hydrolysate

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AU2004279924A1 (en) 2005-04-21
US20130189732A1 (en) 2013-07-25
US8772011B2 (en) 2014-07-08
US20140255550A1 (en) 2014-09-11
US20110097445A1 (en) 2011-04-28
CA2539693A1 (en) 2005-04-21
CN1867668A (zh) 2006-11-22
US7892808B2 (en) 2011-02-22
US8377677B2 (en) 2013-02-19
EP2308966A1 (de) 2011-04-13
US9131711B2 (en) 2015-09-15
EP1673451A1 (de) 2006-06-28
JP2012095666A (ja) 2012-05-24
US20090047387A1 (en) 2009-02-19
EP2284259A3 (de) 2011-06-15
DE602004030595D1 (de) 2011-01-27
EP1673451B1 (de) 2010-12-15
WO2005035747A1 (en) 2005-04-21
BRPI0414959A (pt) 2006-11-07
JP2007509603A (ja) 2007-04-19
EP2284259A2 (de) 2011-02-16

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