ATE521594T1 - Verfahren zur herstellung von chinolin-3- carbonsäureverbindungen - Google Patents
Verfahren zur herstellung von chinolin-3- carbonsäureverbindungenInfo
- Publication number
- ATE521594T1 ATE521594T1 AT02700735T AT02700735T ATE521594T1 AT E521594 T1 ATE521594 T1 AT E521594T1 AT 02700735 T AT02700735 T AT 02700735T AT 02700735 T AT02700735 T AT 02700735T AT E521594 T1 ATE521594 T1 AT E521594T1
- Authority
- AT
- Austria
- Prior art keywords
- branched
- alkyl group
- carboxylic acid
- formula
- acid compounds
- Prior art date
Links
- DJXNJVFEFSWHLY-UHFFFAOYSA-N quinoline-3-carboxylic acid Chemical class C1=CC=CC2=CC(C(=O)O)=CN=C21 DJXNJVFEFSWHLY-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- 125000004400 (C1-C12) alkyl group Chemical group 0.000 abstract 3
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 125000005913 (C3-C6) cycloalkyl group Chemical group 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- 239000003377 acid catalyst Substances 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- GSEZYWGNEACOIW-UHFFFAOYSA-N bis(2-aminophenyl)methanone Chemical compound NC1=CC=CC=C1C(=O)C1=CC=CC=C1N GSEZYWGNEACOIW-UHFFFAOYSA-N 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- -1 keto ester Chemical class 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2001058243 | 2001-03-02 | ||
| PCT/JP2002/001645 WO2002070488A1 (en) | 2001-03-02 | 2002-02-25 | Process for producing quinoline-3-carboxylic acid compound |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE521594T1 true ATE521594T1 (de) | 2011-09-15 |
Family
ID=18917994
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02700735T ATE521594T1 (de) | 2001-03-02 | 2002-02-25 | Verfahren zur herstellung von chinolin-3- carbonsäureverbindungen |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US6852862B2 (de) |
| EP (1) | EP1375487B1 (de) |
| JP (1) | JP4300457B2 (de) |
| KR (1) | KR100835031B1 (de) |
| CN (1) | CN1234691C (de) |
| AT (1) | ATE521594T1 (de) |
| AU (1) | AU2002233708B2 (de) |
| CA (1) | CA2439663C (de) |
| TW (1) | TWI233928B (de) |
| WO (1) | WO2002070488A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006088246A1 (ja) * | 2005-02-18 | 2006-08-24 | Takeda Pharmaceutical Company Limited | Ｇｐｒ３４受容体機能調節剤 |
| US9603848B2 (en) | 2007-06-08 | 2017-03-28 | Senomyx, Inc. | Modulation of chemosensory receptors and ligands associated therewith |
| ES2915065T3 (es) | 2008-07-31 | 2022-06-20 | Firmenich Incorporated | Procedimientos para hacer potenciadores del sabor dulce |
| WO2010014813A2 (en) | 2008-07-31 | 2010-02-04 | Senomyx, Inc. | Compositions comrpising sweetness enhancers and methods of making them |
| WO2012021837A2 (en) * | 2010-08-12 | 2012-02-16 | Senomyx, Inc. | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer |
| BR112015002380B1 (pt) | 2012-08-06 | 2021-09-28 | Firmenich Incorporated | Composto, composições ingeríveis, processos para aumentar o sabor doce de composição e formulação flavorizante concentrada |
| JO3155B1 (ar) | 2013-02-19 | 2017-09-20 | Senomyx Inc | معدِّل نكهة حلوة |
| CN103467373B (zh) * | 2013-09-05 | 2015-07-08 | 南京欧信医药技术有限公司 | 一种喹啉类化合物的合成方法 |
| BR112021002261A2 (pt) | 2018-08-07 | 2021-05-04 | Firmenich Incorporated | 2,2-dióxidos de 4-amino-1h-benzo[c][1,2,6]tiadiazina 5-substituídos e formulações e usos dos mesmos |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5753675A (en) * | 1989-03-03 | 1998-05-19 | Novartis Pharmaceuticals Corporation | Quinoline analogs of mevalonolactone and derivatives thereof |
| TW205037B (de) * | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
| JPH06340658A (ja) * | 1993-04-08 | 1994-12-13 | Kyowa Hakko Kogyo Co Ltd | ベンゾイミダゾール誘導体 |
| JPH0769890A (ja) * | 1993-06-29 | 1995-03-14 | Takeda Chem Ind Ltd | キノリンまたはキナゾリン誘導体を含んでなる医薬組成物 |
| ATE188377T1 (de) * | 1993-06-29 | 2000-01-15 | Takeda Chemical Industries Ltd | Chinoline oder chinazolin-derivate und deren verwendung zur herstellung eines medikaments für die behandlung von osteoporose |
| EP0749426A1 (de) * | 1994-03-08 | 1996-12-27 | Takeda Chemical Industries, Ltd. | Chinolin- oder chinazolinderivate als entzündunshemmende mitteln, insbesondere zur behandlung von arthritis |
-
2002
- 2002-02-25 US US10/468,350 patent/US6852862B2/en not_active Expired - Fee Related
- 2002-02-25 JP JP2002569808A patent/JP4300457B2/ja not_active Expired - Fee Related
- 2002-02-25 AU AU2002233708A patent/AU2002233708B2/en not_active Ceased
- 2002-02-25 CA CA2439663A patent/CA2439663C/en not_active Expired - Fee Related
- 2002-02-25 WO PCT/JP2002/001645 patent/WO2002070488A1/ja not_active Ceased
- 2002-02-25 KR KR1020037011495A patent/KR100835031B1/ko not_active Expired - Fee Related
- 2002-02-25 EP EP02700735A patent/EP1375487B1/de not_active Expired - Lifetime
- 2002-02-25 AT AT02700735T patent/ATE521594T1/de not_active IP Right Cessation
- 2002-02-25 CN CNB028058925A patent/CN1234691C/zh not_active Expired - Fee Related
- 2002-03-01 TW TW091103838A patent/TWI233928B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| KR100835031B1 (ko) | 2008-06-03 |
| EP1375487A1 (de) | 2004-01-02 |
| CN1494531A (zh) | 2004-05-05 |
| EP1375487A4 (de) | 2005-03-02 |
| KR20030082947A (ko) | 2003-10-23 |
| US6852862B2 (en) | 2005-02-08 |
| CA2439663C (en) | 2012-04-03 |
| WO2002070488A1 (en) | 2002-09-12 |
| JP4300457B2 (ja) | 2009-07-22 |
| TWI233928B (en) | 2005-06-11 |
| US20040073034A1 (en) | 2004-04-15 |
| JPWO2002070488A1 (ja) | 2004-09-24 |
| CA2439663A1 (en) | 2002-09-12 |
| EP1375487B1 (de) | 2011-08-24 |
| AU2002233708B2 (en) | 2007-02-08 |
| CN1234691C (zh) | 2006-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |