ATE546443T1 - Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze - Google Patents

Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze

Info

Publication number: ATE546443T1
Authority: AT; Austria
Prior art keywords: benzothiophen; ethoxy; salts; producing; propionic acid
Prior art date: 2005-03-28

Application number

AT10002020T

Other languages

English (en)

Inventor

Akihito Saitoh

Yoshiaki Suzuki

Kenji Yonezawa

Mitsuhide Kawamura

Takahiko Kusanagi

Takashi Nakai

Original Assignee

Toyama Chemical Co Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-03-28

Filing date

2006-03-27

Publication date

2012-03-15

2006-03-27 Application filed by Toyama Chemical Co Ltd filed Critical Toyama Chemical Co Ltd

2012-03-15 Application granted granted Critical

2012-03-15 Publication of ATE546443T1 publication Critical patent/ATE546443T1/de

Links

238000000034 method Methods 0.000 title abstract 2
150000003839 salts Chemical class 0.000 title abstract 2
HQNACSFBDBYLJP-UHFFFAOYSA-N 1-[3-[2-(1-benzothiophen-5-yl)ethoxy]propyl]azetidin-3-ol Chemical compound C1C(O)CN1CCCOCCC1=CC=C(SC=C2)C2=C1 HQNACSFBDBYLJP-UHFFFAOYSA-N 0.000 abstract 1
GEZDICNOLPTCMD-UHFFFAOYSA-N 3-[2-(1-benzothiophen-5-yl)ethoxy]-1-(3-hydroxyazetidin-1-yl)propan-1-one Chemical compound C1C(O)CN1C(=O)CCOCCC1=CC=C(SC=C2)C2=C1 GEZDICNOLPTCMD-UHFFFAOYSA-N 0.000 abstract 1
239000012190 activator Substances 0.000 abstract 1
229910052783 alkali metal Inorganic materials 0.000 abstract 1
150000001340 alkali metals Chemical class 0.000 abstract 1
238000006722 reduction reaction Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/54—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
- C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D333/64—Oxygen atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Neurology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AT10002020T 2005-03-28 2006-03-27 Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze ATE546443T1 (de)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
JP2005090831		2005-03-28
JP2005174738		2005-06-15
JP2005206808		2005-07-15
JP2005230666		2005-08-09

Publications (1)

Publication Number	Publication Date
ATE546443T1 true ATE546443T1 (de)	2012-03-15

Family

ID=37053344

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT10007872T ATE557020T1 (de)	2005-03-28	2006-03-27	Alkyl-3-ä2-(benzoäbüthiophen-5-yl)-ethoxyü- propanoate als intermediate in der herstellung von azetidin-3-ol derivativen
AT10002020T ATE546443T1 (de)	2005-03-28	2006-03-27	Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT10007872T ATE557020T1 (de)	2005-03-28	2006-03-27	Alkyl-3-ä2-(benzoäbüthiophen-5-yl)-ethoxyü- propanoate als intermediate in der herstellung von azetidin-3-ol derivativen

Country Status (22)

Country	Link
US (2)	US7951963B2 (de)
EP (4)	EP2210884B1 (de)
JP (1)	JP5031554B2 (de)
KR (2)	KR101337382B1 (de)
CN (1)	CN101151257B (de)
AT (2)	ATE557020T1 (de)
AU (1)	AU2006229271B2 (de)
BR (1)	BRPI0609496C8 (de)
CA (2)	CA2799659C (de)
CY (3)	CY1112956T1 (de)
DK (2)	DK2210884T3 (de)
ES (3)	ES2398934T3 (de)
IL (2)	IL186044A (de)
MX (1)	MX2007011938A (de)
NO (3)	NO340071B1 (de)
NZ (2)	NZ583580A (de)
PL (3)	PL2210884T3 (de)
PT (3)	PT2248809E (de)
SG (1)	SG155251A1 (de)
SI (3)	SI2248809T1 (de)
WO (1)	WO2006104088A1 (de)
ZA (1)	ZA200708262B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BRPI0213393B8 (pt)	2001-10-19	2021-05-25	Fujifilm Toyama Chemical Co Ltd	derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
SI2248809T1 (sl) *	2005-03-28	2012-09-28	Toyama Chemical Co Ltd	Alkil-3-(2-(benzo(b)tiofen-5-il)-etoksi)-propanoati kot vmesniki v proizvodnji derivatov azetidin-3-ola
JP4902247B2 (ja) *	2005-04-08	2012-03-21	富山化学工業株式会社	２−（１−ベンゾチオフェン−５−イル）エタノールの新規製造法およびその中間体
NZ571803A (en)	2006-04-07	2011-12-22	Vertex Pharma	Amide indole derivatives as modulators of ATP-binding cassette transporters
US7645789B2 (en)	2006-04-07	2010-01-12	Vertex Pharmaceuticals Incorporated	Indole derivatives as CFTR modulators
USRE50453E1 (en)	2006-04-07	2025-06-10	Vertex Pharmaceuticals Incorporated	Indole derivatives as CFTR modulators
US10022352B2 (en)	2006-04-07	2018-07-17	Vertex Pharmaceuticals Incorporated	Modulators of ATP-binding cassette transporters
CA2659835A1 (en) *	2006-08-04	2008-02-07	Toyama Chemical Co., Ltd.	Protein kinase c activity enhancer containing alkyl ether derivative or salt thereof
US8563573B2 (en)	2007-11-02	2013-10-22	Vertex Pharmaceuticals Incorporated	Azaindole derivatives as CFTR modulators
JP5763313B2 (ja) *	2009-09-03	2015-08-12	富山化学工業株式会社	２−（１−ベンゾチオフェン−５−イル）エタノールの製造法
JP5592205B2 (ja) *	2009-09-03	2014-09-17	富山化学工業株式会社	（１−ベンゾチオフェン−５−イル）酢酸またはその塩の製造法
US8802868B2 (en)	2010-03-25	2014-08-12	Vertex Pharmaceuticals Incorporated	Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
ES2608474T3 (es) *	2010-04-22	2017-04-11	Vertex Pharmaceuticals Incorporated	Proceso de producción de compuestos indol cycloalkylcarboxamido
JP6004307B2 (ja) *	2010-07-26	2016-10-05	富山化学工業株式会社	３−（２−（１−ベンゾチオフェン−５−イル）エトキシ）プロピオン酸の塩またはその水和物およびその製造法
WO2012116942A1 (de)	2011-03-02	2012-09-07	Bayer Cropscience Ag	Verfahren zur herstellung von aryl- und heteroarylessigsäure-derivaten
WO2013047786A1 (ja)	2011-09-30	2013-04-04	日本化成株式会社	重合性無機粒子分散剤、該重合性無機粒子分散剤を含む無機有機複合粒子、および無機有機樹脂複合材
BR112014020434B1 (pt) *	2012-02-22	2021-10-13	Fujifilm Toyama Chemical Co., Ltd.	Composição farmacêutica sólida
WO2014014841A1 (en)	2012-07-16	2014-01-23	Vertex Pharmaceuticals Incorporated	Pharmaceutical compositions of (r)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-n-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1h-indol-5-yl) cyclopropanecarboxamide and administration thereof
BR112016017747A2 (pt)	2014-01-31	2017-08-08	Toyama Chemical Co Ltd	Agente de intensificação de efeito de reabilitação pós lesão de nervo compreendendo derivados de éter de alquila ou sal do mesmo
ES2885181T3 (es)	2014-04-15	2021-12-13	Vertex Pharma	Composiciones farmacéuticas para el tratamiento de enfermedades mediadas por el regulador de la conductancia transmembrana de fibrosis quística
RU2733381C2 (ru)	2016-03-31	2020-10-01	Тояма Кемикал Ко., Лтд.	Способ получения 5-(бромметил)-1-бензотиофена

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA844616B (en)	1983-06-20	1986-02-26	Merck & Co Inc	2-sulfamoylbenzo(b)thiophene derivatives for the treatment of elevated intraocular pressure
NZ208444A (en)	1983-06-20	1987-08-31	Merck & Co Inc	2-thiophene derivatives and pharmaceutical compositions
US4668697A (en) *	1983-10-31	1987-05-26	Merck & Co., Inc.	Elevated intraocular pressure lowering benzo-[b]-thiophene-2-sulfonamide derivatives, compositions, and method of use therefor
CH673100A5 (de)	1987-08-10	1990-02-15	Josef Paul Huser
JPH04182463A (ja)	1990-11-17	1992-06-30	Sumitomo Seika Chem Co Ltd	ハロゲノチオフェノール類およびその誘導体の製造方法
JPH05140086A (ja)	1991-09-26	1993-06-08	Sumitomo Seika Chem Co Ltd	ハロゲノチオフエノールの製造方法および精製方法
JPH05178816A (ja)	1991-12-28	1993-07-20	Sumitomo Seika Chem Co Ltd	ハロゲノチオフェノールの製造方法
JP2641363B2 (ja)	1992-04-22	1997-08-13	三共株式会社	新規なフェネチルアルコール及びその製法
GB9404775D0 (en)	1994-03-11	1994-04-27	Payne P P Ltd	Improvements in or relating to article tagging
JPH08143533A (ja)	1994-11-24	1996-06-04	Sumitomo Seika Chem Co Ltd	ハロチオフェノール類の製造方法
JPH1043967A (ja)	1996-08-06	1998-02-17	Calsonic Corp	カシメ装置
AU6519798A (en)	1997-03-31	1998-10-22	Toyama Chemical Co. Ltd.	Process for producing 2-(benzo{b}thiophen-5-yl)-2-hydroxyacetic acid derivatives, optically active compounds thereof, or salts of both
GB9706574D0 (en)	1997-04-01	1997-05-21	Zeneca Ltd	Cyano substituted cycloalkanes
JPH1112238A (ja)	1997-06-23	1999-01-19	Kao Corp	１−（β−ヒドロキシエチル）−２，５−ジアミノベンゼン又はその塩の製造法
JPH1143455A (ja)	1997-07-25	1999-02-16	Mitsubishi Chem Corp	ハロゲン化アルコールの製造方法
AU1506499A (en)	1997-12-12	1999-07-05	Toyama Chemical Co. Ltd.	Alkyl ether derivatives or salts thereof and calcium antagonists containing the same
EP0993105B1 (de)	1998-10-07	2003-01-08	STMicroelectronics S.r.l.	Leistungsübertragungssteueurung in Sperrwandler durch lastabhängige Austastmodulation
JP4182463B2 (ja)	2000-07-19	2008-11-19	富士電機デバイステクノロジー株式会社	磁気ディスク評価装置およびその方法
WO2002100850A1 (en)	2001-06-08	2002-12-19	Kuraray Co., Ltd.	Processes for preparation of heterocyclic compounds
BRPI0213393B8 (pt) *	2001-10-19	2021-05-25	Fujifilm Toyama Chemical Co Ltd	derivados de éter alquílico, ou um de seus sais, processo para produzir um derivado de éter alquílico, derivado de alquil-amida, ou um de seus sais, e, composição farmacêutica
ES2391273T3 (es) *	2003-04-17	2012-11-23	Toyama Chemical Co., Ltd.	Agente preventivo/curativo para enfermedades del nervio retiniano que contiene derivados de éter alquílico o sus sales
JP2005012291A (ja)	2003-06-17	2005-01-13	National Institute Of Information & Communication Technology	Ｔｖ会議用モバイル動画通信端末
US20050032873A1 (en) *	2003-07-30	2005-02-10	Wyeth	3-Amino chroman and 2-amino tetralin derivatives
WO2005019200A2 (en) *	2003-08-14	2005-03-03	Icos Corporation	Aryl piperidine derivatives as vla-1 integrin antagonists and uses thereof
SI2248809T1 (sl)	2005-03-28	2012-09-28	Toyama Chemical Co Ltd	Alkil-3-(2-(benzo(b)tiofen-5-il)-etoksi)-propanoati kot vmesniki v proizvodnji derivatov azetidin-3-ola
CA2648898C (en)	2006-04-26	2015-01-20	Toyama Chemical Co., Ltd.	Neurogenesis inducer or neuropathy therapeutic agent comprising alkyl ether derivative or salt thereof

2006
- 2006-03-27 SI SI200631383T patent/SI2248809T1/sl unknown
- 2006-03-27 EP EP10002020A patent/EP2210884B1/de not_active Expired - Lifetime
- 2006-03-27 SI SI200631324T patent/SI2210884T1/sl unknown
- 2006-03-27 PT PT10007872T patent/PT2248809E/pt unknown
- 2006-03-27 KR KR1020127032936A patent/KR101337382B1/ko not_active Expired - Lifetime
- 2006-03-27 ES ES11002265T patent/ES2398934T3/es not_active Expired - Lifetime
- 2006-03-27 ES ES10007872T patent/ES2384312T3/es not_active Expired - Lifetime
- 2006-03-27 DK DK10002020.5T patent/DK2210884T3/da active
- 2006-03-27 BR BRPI0609496A patent/BRPI0609496C8/pt active IP Right Grant
- 2006-03-27 AT AT10007872T patent/ATE557020T1/de active
- 2006-03-27 PT PT10002020T patent/PT2210884E/pt unknown
- 2006-03-27 ZA ZA200708262A patent/ZA200708262B/xx unknown
- 2006-03-27 US US11/909,809 patent/US7951963B2/en active Active
- 2006-03-27 CA CA2799659A patent/CA2799659C/en not_active Expired - Lifetime
- 2006-03-27 AU AU2006229271A patent/AU2006229271B2/en not_active Expired
- 2006-03-27 EP EP11002265A patent/EP2348022B1/de not_active Expired - Lifetime
- 2006-03-27 NZ NZ583580A patent/NZ583580A/en not_active IP Right Cessation
- 2006-03-27 AT AT10002020T patent/ATE546443T1/de active
- 2006-03-27 KR KR1020077024039A patent/KR101283930B1/ko not_active Expired - Lifetime
- 2006-03-27 JP JP2007510482A patent/JP5031554B2/ja not_active Expired - Lifetime
- 2006-03-27 ES ES10002020T patent/ES2380443T3/es not_active Expired - Lifetime
- 2006-03-27 SI SI200631556T patent/SI2348022T1/sl unknown
- 2006-03-27 EP EP10007872A patent/EP2248809B1/de not_active Expired - Lifetime
- 2006-03-27 DK DK10007872.4T patent/DK2248809T3/da active
- 2006-03-27 NZ NZ561672A patent/NZ561672A/en not_active IP Right Cessation
- 2006-03-27 PL PL10002020T patent/PL2210884T3/pl unknown
- 2006-03-27 PT PT110022654T patent/PT2348022E/pt unknown
- 2006-03-27 CA CA2600381A patent/CA2600381C/en not_active Expired - Lifetime
- 2006-03-27 MX MX2007011938A patent/MX2007011938A/es active IP Right Grant
- 2006-03-27 PL PL10007872T patent/PL2248809T3/pl unknown
- 2006-03-27 CN CN2006800102653A patent/CN101151257B/zh not_active Expired - Lifetime
- 2006-03-27 PL PL11002265T patent/PL2348022T3/pl unknown
- 2006-03-27 WO PCT/JP2006/306127 patent/WO2006104088A1/ja not_active Ceased
- 2006-03-27 SG SG200905724-1A patent/SG155251A1/en unknown
- 2006-03-27 EP EP06730075A patent/EP1864978A4/de not_active Withdrawn
2007
- 2007-09-12 NO NO20074618A patent/NO340071B1/no unknown
- 2007-09-18 IL IL186044A patent/IL186044A/en active IP Right Grant
2011
- 2011-01-06 US US12/985,616 patent/US8273902B2/en not_active Expired - Lifetime
- 2011-07-21 IL IL214245A patent/IL214245A/en active IP Right Grant
2012
- 2012-05-08 CY CY20121100434T patent/CY1112956T1/el unknown
- 2012-06-27 CY CY20121100566T patent/CY1112885T1/el unknown
2013
- 2013-01-25 CY CY20131100075T patent/CY1113571T1/el unknown
2016
- 2016-09-07 NO NO20161419A patent/NO340420B1/no unknown
- 2016-09-07 NO NO20161418A patent/NO340366B1/no unknown

Also Published As

Publication number	Publication date
CY1112885T1 (el)	2016-04-13
NZ583580A (en)	2010-10-29
CN101151257A (zh)	2008-03-26
CA2600381A1 (en)	2006-10-05
CA2799659A1 (en)	2006-10-05
JP5031554B2 (ja)	2012-09-19
PT2210884E (pt)	2012-04-10
EP2248809A1 (de)	2010-11-10
US20090069576A1 (en)	2009-03-12
WO2006104088A1 (ja)	2006-10-05
NO340071B1 (no)	2017-03-06
CY1112956T1 (el)	2016-04-13
EP1864978A4 (de)	2009-07-01
EP2348022A1 (de)	2011-07-27
ES2384312T3 (es)	2012-07-03
EP1864978A1 (de)	2007-12-12
SI2248809T1 (sl)	2012-09-28
KR20130010090A (ko)	2013-01-25
NO340366B1 (no)	2017-04-10
PL2348022T3 (pl)	2013-06-28
NZ561672A (en)	2010-04-30
IL186044A (en)	2013-12-31
EP2248809B1 (de)	2012-05-09
KR101337382B1 (ko)	2013-12-06
BRPI0609496C1 (pt)	2021-05-11
PL2248809T3 (pl)	2012-10-31
JPWO2006104088A1 (ja)	2008-09-04
MX2007011938A (es)	2008-03-14
ATE557020T1 (de)	2012-05-15
NO340420B1 (no)	2017-04-18
US7951963B2 (en)	2011-05-31
IL186044A0 (en)	2008-02-09
EP2210884A3 (de)	2010-09-22
KR101283930B1 (ko)	2013-07-16
DK2210884T3 (da)	2012-03-26
EP2348022B1 (de)	2013-01-09
NO20161419A1 (no)	2016-06-07
SI2210884T1 (sl)	2012-06-29
EP2210884A2 (de)	2010-07-28
CA2600381C (en)	2013-11-12
CY1113571T1 (el)	2016-06-22
BRPI0609496C8 (pt)	2021-05-25
US20110098484A1 (en)	2011-04-28
CA2799659C (en)	2014-12-02
DK2248809T3 (da)	2012-06-18
BRPI0609496A2 (pt)	2011-10-18
ES2380443T3 (es)	2012-05-11
EP2210884B1 (de)	2012-02-22
ZA200708262B (en)	2009-01-28
AU2006229271A1 (en)	2006-10-05
PL2210884T3 (pl)	2012-07-31
KR20080008334A (ko)	2008-01-23
PT2348022E (pt)	2013-02-13
SI2348022T1 (sl)	2013-05-31
NO20074618L (no)	2007-10-25
IL214245A (en)	2014-12-31
PT2248809E (pt)	2012-07-02
NO20161418A1 (no)	2007-10-25
IL214245A0 (en)	2011-08-31
ES2398934T3 (es)	2013-03-22
BRPI0609496B1 (pt)	2020-11-24
SG155251A1 (en)	2009-09-30
CN101151257B (zh)	2012-07-18
AU2006229271B2 (en)	2012-02-09
US8273902B2 (en)	2012-09-25

Publication	Publication Date	Title
ATE546443T1 (de)	2012-03-15	Prozess zur herstellung von 1-(3-(2-(1- benzothiophen-5-yl)-ethoxy)propionsäure sowie deren salze
DE602007006921D1 (de)	2010-07-15	Verfahren zur herstellung von zellstoff und daraus hergestellte artikel
WO2006076611A3 (en)	2007-03-01	Production of metal nanoparticles
MY149879A (en)	2013-10-31	Process for producing acrylic acid, apparatus for producing acrylic acid, and composition for producing acrylic acid
ATE486857T1 (de)	2010-11-15	Verfahren zur herstellung von telmisartan
EP1950208A4 (de)	2009-07-22	Verfahren zur herstellung von 6,6-dimethyl-3-oxabicyclo[3.1.0]hexan-2-on
BRPI0503815A (pt)	2006-04-18	processo para produção de mercaptoorganil (alcoxissilano)
EP1721895A4 (de)	2008-02-27	Verfahren zur herstellung von cumenhydroperoxid
ATE446374T1 (de)	2009-11-15	Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
ATE526299T1 (de)	2011-10-15	Verfahren zur synthese von ethynylcyclopropan
ATE489355T1 (de)	2010-12-15	Mandelsäurederivate und deren herstellung
TW200512185A (en)	2005-04-01	Chemical process
EP2000453A4 (de)	2014-03-12	Verfahren zur herstellung von alkohol durch verwendung von kohlendioxid als rohstoff
ATE424465T1 (de)	2009-03-15	Verfahren zur herstellung von citronellal
DE602005013007D1 (de)	2009-04-09	Verfahren zur herstellung von lactonen
ATE446960T1 (de)	2009-11-15	Verfahren zur herstellung von ziprasidone
DE602004001462D1 (de)	2006-08-17	Verfahren zur weinherstellung mit mazeration durch mikrowellen
DE502007003366D1 (de)	2010-05-12	Verfahren zur herstellung eines produktes mit polymermatrix, daraus bestehende implantate sowie deren verwendung
ATE499337T1 (de)	2011-03-15	Verfahren zur herstellung von 2,2,3- trimethylcyclopent-3-enecarbaldehyd (campholytisches aldehyd)
ATE415386T1 (de)	2008-12-15	Verfahren zur herstellung von 4-hydroxyalkylamino-2-nitro-anisolen
CN106750890A (zh)	2017-05-31	一种用于深度钻孔控制的pcb板盖板
ATE430735T1 (de)	2009-05-15	Verfahren zur herstellung von 10,11-dihydro-10- hydroxy-5-h-dibenzäb,füazepin-5-carbonsäureamid
ATE407064T1 (de)	2008-09-15	Verfahren zur herstellung einer fälschungssicheren verpackung und nach diesem verfahren hergestellte verpackung