BRPI0414313A - inibidores de citocinas - Google Patents

inibidores de citocinas

Info

Publication number
BRPI0414313A
BRPI0414313A BRPI0414313-2A BRPI0414313A BRPI0414313A BR PI0414313 A BRPI0414313 A BR PI0414313A BR PI0414313 A BRPI0414313 A BR PI0414313A BR PI0414313 A BRPI0414313 A BR PI0414313A
Authority
BR
Brazil
Prior art keywords
cytokine inhibitors
cytokine
usable
agents
inhibitors
Prior art date
Application number
BRPI0414313-2A
Other languages
English (en)
Inventor
Erik Boman
Susana C Ceide
Russell Dahl
Nancy G J Delaet
Justin Ernst
Antonio G Montalban
Jeffrey D Kahl
Christopher Larson
Stephen Miller
Hiroshi Nakanishi
Edward Roberts
Eddine Saiah
Robert Sullivan
Zhijun Wang
Original Assignee
Kemia Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kemia Inc filed Critical Kemia Inc
Publication of BRPI0414313A publication Critical patent/BRPI0414313A/pt

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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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Abstract

"INIBIDORES DE CITOCINAS". A presente invenção provê compostos de baixo peso molecular utilizáveis como inibidores de citocinas, e composições dos mesmos. Particularmente, os compostos da invenção são utilizáveis como agentes antiinflamatórios. São ainda providos métodos para a preparação destes agentes e seu uso na prevenção ou tratamento de condições mediadas por citocinas, como artrite.
BRPI0414313-2A 2003-09-11 2004-09-10 inibidores de citocinas BRPI0414313A (pt)

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US50256903P 2003-09-11 2003-09-11
US53123403P 2003-12-18 2003-12-18
US57570404P 2004-05-28 2004-05-28
US58501204P 2004-07-02 2004-07-02
PCT/US2004/029372 WO2005023761A2 (en) 2003-09-11 2004-09-10 Cytokine inhibitors

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US7749999B2 (en) 2010-07-06
AU2004270733B2 (en) 2011-05-19
EP1670787A2 (en) 2006-06-21
US7919617B2 (en) 2011-04-05
WO2005023761A2 (en) 2005-03-17
WO2005023761A3 (en) 2005-07-14
US20100273797A1 (en) 2010-10-28
US20050107399A1 (en) 2005-05-19
AU2004270733A1 (en) 2005-03-17
EP1670787A4 (en) 2009-04-22
JP2007505127A (ja) 2007-03-08
MXPA06002853A (es) 2006-06-14
SG146624A1 (en) 2008-10-30
US20100093735A1 (en) 2010-04-15
EP1670787B1 (en) 2012-05-30
US20100093734A1 (en) 2010-04-15
CN102060806A (zh) 2011-05-18
IL174010A0 (en) 2006-08-01
US7897599B2 (en) 2011-03-01
JP4895811B2 (ja) 2012-03-14
CA2538820A1 (en) 2005-03-17

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