CO6470876A2 - 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak. - Google Patents

3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak.

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Publication number
CO6470876A2
CO6470876A2 CO11169879A CO11169879A CO6470876A2 CO 6470876 A2 CO6470876 A2 CO 6470876A2 CO 11169879 A CO11169879 A CO 11169879A CO 11169879 A CO11169879 A CO 11169879A CO 6470876 A2 CO6470876 A2 CO 6470876A2
Authority
CO
Colombia
Prior art keywords
pirimidin
pirrolo
heptano
pirazol
octano
Prior art date
Application number
CO11169879A
Other languages
English (en)
Spanish (es)
Inventor
Yun-Long Li
James D Rodgers
Original Assignee
Incyte Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42246359&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO6470876(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Incyte Corp filed Critical Incyte Corp
Publication of CO6470876A2 publication Critical patent/CO6470876A2/es

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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/525—Isoalloxazines, e.g. riboflavins, vitamin B2
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    • A61P5/00—Drugs for disorders of the endocrine system
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

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CO11169879A 2009-05-22 2011-12-09 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak. CO6470876A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US18058209P 2009-05-22 2009-05-22

Publications (1)

Publication Number Publication Date
CO6470876A2 true CO6470876A2 (es) 2012-06-29

Family

ID=42246359

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11169879A CO6470876A2 (es) 2009-05-22 2011-12-09 3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il]octano- o heptano-nitrilo como inhibidores de jak.

Country Status (36)

Country Link
US (3) US8604043B2 (fr)
EP (2) EP2432472B1 (fr)
JP (2) JP6172939B2 (fr)
KR (1) KR20120030447A (fr)
CN (2) CN106967070A (fr)
AR (1) AR076920A1 (fr)
AU (1) AU2010249443B2 (fr)
BR (1) BRPI1012108B8 (fr)
CA (1) CA2761954C (fr)
CL (1) CL2011002955A1 (fr)
CO (1) CO6470876A2 (fr)
CR (1) CR20110621A (fr)
CY (1) CY1122425T1 (fr)
DK (1) DK2432472T3 (fr)
EA (1) EA020494B1 (fr)
EC (1) ECSP11011534A (fr)
ES (1) ES2761300T3 (fr)
HR (1) HRP20192203T1 (fr)
HU (1) HUE046493T2 (fr)
IL (1) IL216359A (fr)
LT (1) LT2432472T (fr)
ME (1) ME03556B (fr)
MX (1) MX2011012262A (fr)
MY (1) MY161416A (fr)
NZ (1) NZ596374A (fr)
PE (1) PE20120371A1 (fr)
PL (1) PL2432472T3 (fr)
PT (1) PT2432472T (fr)
RS (1) RS59632B1 (fr)
SG (2) SG176111A1 (fr)
SI (1) SI2432472T1 (fr)
SM (1) SMT201900698T1 (fr)
TW (1) TWI484962B (fr)
UA (1) UA106078C2 (fr)
WO (1) WO2010135621A1 (fr)
ZA (1) ZA201108541B (fr)

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TW201406761A (zh) 2012-05-18 2014-02-16 Incyte Corp 做爲ｊａｋ抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
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CN113384546A (zh) 2012-11-15 2021-09-14 因赛特公司 鲁索利替尼的缓释剂型
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WO2018189335A1 (fr) 2017-04-13 2018-10-18 INSERM (Institut National de la Santé et de la Recherche Médicale) Procédés de diagnostic et de traitement d'un adénocarcinome canalaire pancréatique
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HUE046493T2 (hu) 2020-03-30
TWI484962B (zh) 2015-05-21
US9623029B2 (en) 2017-04-18
AR076920A1 (es) 2011-07-20
US9216984B2 (en) 2015-12-22
WO2010135621A1 (fr) 2010-11-25
BRPI1012108A2 (pt) 2016-03-29
PT2432472T (pt) 2019-12-09
US20140073657A1 (en) 2014-03-13
US20160067253A1 (en) 2016-03-10
US8604043B2 (en) 2013-12-10
IL216359A (en) 2016-09-29
SG176111A1 (en) 2011-12-29
CR20110621A (es) 2012-02-09

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